PT  - JOURNAL ARTICLE
AU  - R. B. PARKER
AU  - C. GOLDFINE
TI  - STOICHIOMETRY OF THE DRUG-NICOTINIC RECEPTOR INTERACTION
DP  - 1973 Jun 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 649--652
VI  - 185
IP  - 3
4099  - http://jpet.aspetjournals.org/content/185/3/649.short
4100  - http://jpet.aspetjournals.org/content/185/3/649.full
SO  - J Pharmacol Exp Ther1973 Jun 01; 185
AB  - Appropriate estimation of drug-receptor dissociation constants with pharmacological techniques depends upon the stoichiometry of the reaction involved. The data presented in this paper suggest that both stimulant drugs and competitive antagonists interact on a one-to-one basis with the nicotinic receptor of the guinea-pig lumbrical muscle. © 1973 by The Williams & Wilkins Co.