TY - JOUR T1 - PREVENTION OF PULMONARY EMPHYSEMA IN RATS BY PROGESTERONE JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 197 LP - 204 VL - 161 IS - 2 AU - Haruo Ito AU - Domingo M. Aviado Y1 - 1968/06/01 UR - http://jpet.aspetjournals.org/content/161/2/197.abstract N2 - Pulmonary emphysema was induced experimentally by tracheal ligation and intratracheal injection of phytohemagglutinin. The functional consequences consisted of elevated functional residual capacity, increase in pulmonary resistance and impaired minute volume response to inhalation of low oxygen mixture. Daily injections of progesterone for 7 weeks prevented the appearance of experimental emphysema. © 1968 by The Williams & Wilkins Company ER -