PT - JOURNAL ARTICLE AU - Elder, John T. AU - Shellenberger, M. Kent TI - ANTAGONISM OF LYSERGIC ACID DIETHYLAMIDE (LSD)-INDUCED HYPERTHERMIA DP - 1962 Jun 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 293--297 VI - 136 IP - 3 4099 - http://jpet.aspetjournals.org/content/136/3/293.short 4100 - http://jpet.aspetjournals.org/content/136/3/293.full SO - J Pharmacol Exp Ther1962 Jun 01; 136 AB - The pyretogenic response to LSD was prevented by 60-minute pretreatment with PBA. Reserpine given 24 hours before LSD and guanethidine 18.5 hours prior to LSD produced the most effective attenuation of the response. Reserpine given immediately before LSD caused an increased response to LSD, probably by increasing the metabolic rate. Hexamethonium had no effect upon the LSD response.