PT  - JOURNAL ARTICLE
AU  - Buzard, James A.
AU  - Conklin, John D.
AU  - O'Keefe, Eugene
AU  - Paul, Mary F.
TI  - STUDIES ON THE ABSORPTION, DISTRIBUTION AND ELIMINATION OF NITROFURANTOIN IN THE RAT
DP  - 1961 Jan 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 38--43
VI  - 131
IP  - 1
4099  - http://jpet.aspetjournals.org/content/131/1/38.short
4100  - http://jpet.aspetjournals.org/content/131/1/38.full
SO  - J Pharmacol Exp Ther1961 Jan 01; 131
AB  - The studies reported indicate that nitrofurantoin is rapidly absorbed in the rat. It has been shown that the small intestine is the chief site of absorption. Experiments in which rats have been subjected to various surgical procedures confirm that urinary excretion of nitrofurantoin is the primary route of disposal and suggest that the remainder of the drug is rapidly catabolized by body tissues.