PT  - JOURNAL ARTICLE
AU  - Walter Lovenberg
AU  - Robert J. Levine
AU  - Albert Sjoerdsma
TI  - A SENSITIVE ASSAY OF MONOAMINE OXIDASE ACTIVITY <em>IN VITRO:</em> APPLICATION TO HEART AND SYMPATHETIC GANGLIA
DP  - 1962 Jan 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 7--10
VI  - 135
IP  - 1
4099  - http://jpet.aspetjournals.org/content/135/1/7.short
4100  - http://jpet.aspetjournals.org/content/135/1/7.full
SO  - J Pharmacol Exp Ther1962 Jan 01; 135
AB  - A sensitive method of measuring monoamine oxidase in vitro based on the rate of indoleacetic acid formation from tryptamine is described. The method is particularly suited for studies on organs with low levels of enzyme activity, e.g., dog heart, or on small samples of tissue, such as a sympathetic ganglion. Correlation of the biochemical and pharmacologic effects of MAO inhibitors in such loci will thereby be facilitated.