TY - JOUR T1 - EVALUATION OF BORON COMPOUNDS FOR USE IN NEUTRON CAPTURE THERAPY OF BRAIN TUMORS. I. ANIMAL INVESTIGATIONS JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 117 LP - 122 VL - 134 IS - 1 AU - A. H. Soloway AU - R. L. Wright AU - J. R. Messer Y1 - 1961/10/01 UR - http://jpet.aspetjournals.org/content/134/1/117.abstract N2 - Ten organic boron compounds and boric acid have been evaluated in mice for toxicity. Tumor: brain boron ratios have been studied in animals with subcutaneous transplanted gliomas. Two of the more promising compounds, 3-amino-4-carboxybenzeneboronic acid and m-boronosuccinanilic acid have been studied in cats by both intravenous and intracarotid injection. Tissue concentrations have been determined. ER -