RT Journal Article
SR Electronic
T1 EVALUATION OF BORON COMPOUNDS FOR USE IN NEUTRON CAPTURE THERAPY OF BRAIN TUMORS. I. ANIMAL INVESTIGATIONS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 117
OP 122
VO 134
IS 1
A1 A. H. Soloway
A1 R. L. Wright
A1 J. R. Messer
YR 1961
UL http://jpet.aspetjournals.org/content/134/1/117.abstract
AB Ten organic boron compounds and boric acid have been evaluated in mice for toxicity. Tumor: brain boron ratios have been studied in animals with subcutaneous transplanted gliomas. Two of the more promising compounds, 3-amino-4-carboxybenzeneboronic acid and m-boronosuccinanilic acid have been studied in cats by both intravenous and intracarotid injection. Tissue concentrations have been determined.