PT  - JOURNAL ARTICLE
AU  - Matthews, Richard J.
AU  - Roberts, Barbara J.
TI  - THE EFFECT OF <em>GAMMA</em>-AMINOBUTYRIC ACID ON SYNAPTIC TRANSMISSION IN AUTONOMIC GANGLIA
DP  - 1961 Apr 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 19--22
VI  - 132
IP  - 1
4099  - http://jpet.aspetjournals.org/content/132/1/19.short
4100  - http://jpet.aspetjournals.org/content/132/1/19.full
SO  - J Pharmacol Exp Ther1961 Apr 01; 132
AB  - Gamma-aminobutyric acid (GABA) has been shown to have weak depressant activity on synaptic transmission in the inferior mesenteric ganglion of the decerebrate cat. High doses (100 µg/kg) administered intra arterially were necessary to elicit a depression. The sensitivity of the preparations varied widely and tachyphylaxis was observed in some experiments. No effect could be obtained in the superior cervical ganglion.