RT Journal Article SR Electronic T1 EFFECT OF MORPHINE ON THE SUBJECTIVE RESPONSE OF HUNGER IN NORMAL SUBJECTS JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 63 OP 69 VO 126 IS 1 A1 G. M. Smith A1 H. K. Beecher YR 1959 UL http://jpet.aspetjournals.org/content/126/1/63.abstract AB Eighty-five nonaddict, nonpatient, adult male college and graduate students received the "standard" clinical dose of 10 mg of morphine phosphate per 70 kg of body weight and 1 ml of saline subcutaneously. The several conditions under which medications were given and the methods of obtaining and evaluating various types of subjective hunger response and one type of objective hunger response have been discussed. It is concluded that, in comparison with a placebo, morphine does not reduce the hunger responses studied in the majority of nonpatient, nonaddict subjects and that although it produces a statistically significant group effect in a large sample of subjects (n = 85), this effect is weak in comparison with other subjective responses produced by morphine. © 1959 by The Williams & Wilkins Co.