PT - JOURNAL ARTICLE AU - Georg E. Cronheim AU - I. M. Toekes TI - THE EFFECT OF 2-DIMETHYLAMINOETHANOL (DEANOL) ON ANAPHYLACTOID EDEMA IN RATS DP - 1959 Oct 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 167--170 VI - 127 IP - 2 4099 - http://jpet.aspetjournals.org/content/127/2/167.short 4100 - http://jpet.aspetjournals.org/content/127/2/167.full SO - J Pharmacol Exp Ther1959 Oct 01; 127 AB - 2-Dimethylaminoethanol (deanol) had an inhibitory action on the anaphylactoid edema produced in rat paws by subplantar injection of eggwhite, serotonin, formaldehyde or histamine. The effect could be demonstrated acutely by intraperitoneal injection and, after a time lag, also by chronic oral administration. Presence of the adrenals was not required. The drug was ineffective in the cotton pellet granuloma type of inflammatory reaction.