RT Journal Article SR Electronic T1 ADRENERGIC RECEPTIVE MECHANISM OF CANINE ILEUM JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 146 OP 149 VO 127 IS 2 A1 Raymond P. Ahlquist A1 Bernard Levy YR 1959 UL http://jpet.aspetjournals.org/content/127/2/146.abstract AB The intestinal inhibitory effect of phenylephrine in the dog is blocked by small doses of the alpha adrenergic blocking agents such as Dibozane. The intestinal inhibitory effect of isoproterenol is blocked by small doses of its dichloro analog, DCI. The effect of epinephrinc on the canine ileum is usually not blocked by either kind of blocking agent alone, but is blocked by a combination of the two. It is, therefore, concluded that in terms of our concept of the adrenergic receptive mechanism the canine ileum has both alpha and beta receptors, and that both receptors subserve relaxation or inhibition.