RT Journal Article
SR Electronic
T1 BARBITURATES AS SPINAL ANESTHETICS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 318
OP 321
VO 118
IS 3
A1 F. A. Purdy
A1 B. A. Westfall
YR 1956
UL http://jpet.aspetjournals.org/content/118/3/318.abstract
AB Four barbiturates, namely, pentobarbital, secobarbital, barbital, and thiopental (0.05 ml. of 5 per cent/kgm.), have been used as spinal anesthetics in dogs. These compounds produced complete spinal block persisting approximately the same length of time as resulted from the same volume of 2 per cent procaine solution. No undesirable side effects, either during or after the anesthesia, were observed. It is suggested that these compounds should not be used intrathecally in man for complications have been reported following spinal anesthesia with barbiturates in man.