PT  - JOURNAL ARTICLE
AU  - F. A. Purdy
AU  - B. A. Westfall
TI  - BARBITURATES AS SPINAL ANESTHETICS
DP  - 1956 Nov 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 318--321
VI  - 118
IP  - 3
4099  - http://jpet.aspetjournals.org/content/118/3/318.short
4100  - http://jpet.aspetjournals.org/content/118/3/318.full
SO  - J Pharmacol Exp Ther1956 Nov 01; 118
AB  - Four barbiturates, namely, pentobarbital, secobarbital, barbital, and thiopental (0.05 ml. of 5 per cent/kgm.), have been used as spinal anesthetics in dogs. These compounds produced complete spinal block persisting approximately the same length of time as resulted from the same volume of 2 per cent procaine solution. No undesirable side effects, either during or after the anesthesia, were observed. It is suggested that these compounds should not be used intrathecally in man for complications have been reported following spinal anesthesia with barbiturates in man.