RT Journal Article
SR Electronic
T1 PHARMACOLOGY OF THE RETICULO-ENDOTHELIAL SYSTEM. 1. BLOCKADE BY POLYVINYLPYRROLIDONE (PVP) AS MEASURED WITH RADIO-CHROMIC PHOSPHATE IN THE RABBIT
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 148
OP 152
VO 118
IS 2
A1 Weikel, John H.
A1 Lusky, Lehman M.
YR 1956
UL http://jpet.aspetjournals.org/content/118/2/148.abstract
AB The correlation between polyvinylpyrrolidone storage in the reticulo-endothelial system and functional activity of that system has been examined using radioactive chromic phosphate. Polyvinylpyrrolidone was shown to depress the rate of phagocytosis of the colloid. It also caused a change in the distribution of the chromic phosphate among the organs of the reticuloendothelial system with more taken up by the lungs and less by the spleens of those animals treated with polyvinylpyrrolidone.