PT - JOURNAL ARTICLE AU - Shore, P. A. AU - Pletscher, Alfred AU - Tomich, E. G. AU - Kuntzman, Ronald AU - Brodie, B. B. TI - RELEASE OF BLOOD PLATELET SEROTONIN BY RESERPINE AND LACK OF EFFECT ON BLEEDING TIME DP - 1956 Jun 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 232--236 VI - 117 IP - 2 4099 - http://jpet.aspetjournals.org/content/117/2/232.short 4100 - http://jpet.aspetjournals.org/content/117/2/232.full SO - J Pharmacol Exp Ther1956 Jun 01; 117 AB - The administration of reserpine to rabbits, rats or guinea pigs causes the liberation of serotonin from blood platelets without causing their disruption. The loss of over 90 per cent of platelet serotonin has no significant effect on bleeding time. It is improbable, therefore, that serotonin participates in the mechanism of hemostasis.