RT Journal Article
SR Electronic
T1 ISOLATION OF AN EPOXIDE METABOLITE FROM FAT TISSUES OF DOGS FED HEPTACHLOR
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 259
OP 265
VO 107
IS 3
A1 Davidow, Bernard
A1 Radomski, Jack L.
YR 1953
UL http://jpet.aspetjournals.org/content/107/3/259.abstract
AB 1. A metabolically altered derivative is stored in the fat of dogs fed heptachlor. 2. Countercurrent distribution and adsorption chromatography were used to isolate 76 mgm. of metabolite from 350 gm. of fat. 3. The metabolite has been identified as the epoxide of heptachlor. 4. The existence of a new pathway of biological oxidation, namely, epoxidation, has been demonstrated.