JPET -- Table of Contents (323 [3])

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December 2007; 323 (3)   [Index by Author] [Cover Caption]

       PERSPECTIVES IN PHARMACOLOGY

       BEHAVIORAL PHARMACOLOGY

       CARDIOVASCULAR

       CELLULAR AND MOLECULAR

       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

       METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

       NEUROPHARMACOLOGY

       TOXICOLOGY

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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |

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PERSPECTIVES IN PHARMACOLOGY:

M. Joyeux-Faure: Cellular Protection by Erythropoietin: New Therapeutic Implications?
J Pharmacol Exp Ther 2007 323: 759-762. Published online August 23, 2007; 10.1124/jpet.107.127357 [Abstract] [Full Text] [PDF]

BEHAVIORAL PHARMACOLOGY:

Y. Zhao, G. R. Valdez, É. M. Fekete, J. E. Rivier, W. W. Vale, K. C. Rice, F. Weiss, and E. P. Zorrilla: Subtype-Selective Corticotropin-Releasing Factor Receptor Agonists Exert Contrasting, but Not Opposite, Effects on Anxiety-Related Behavior in Rats
J Pharmacol Exp Ther 2007 323: 846-854. Published online September 12, 2007; 10.1124/jpet.107.123208 [Abstract] [Full Text] [PDF] [Data Supplement]

CARDIOVASCULAR:

Anna Tavridou, Loukas Kaklamanis, Apostolos Papalois, Angeliki P. Kourounakis, Eleni A. Rekka, Panos N. Kourounakis, Avgui Charalambous, and Vangelis G. Manolopoulos: EP2306 [2-(4-Biphenyl)-4-methyl-octahydro-1,4-benzoxazin-2-ol, hydrobromide], A Novel Squalene Synthase Inhibitor, Reduces Atherosclerosis in the Cholesterol-Fed Rabbit
J Pharmacol Exp Ther 2007 323: 794-804. Published online September 5, 2007; 10.1124/jpet.107.126375 [Abstract] [Full Text] [PDF]

Mahmood Khan, Iyyapu K. Mohan, Vijay Kumar Kutala, Damodar Kumbala, and Periannan Kuppusamy: Cardioprotection by Sulfaphenazole, a Cytochrome P450 Inhibitor: Mitigation of Ischemia-Reperfusion Injury by Scavenging of Reactive Oxygen Species
J Pharmacol Exp Ther 2007 323: 813-821. Published online September 14, 2007; 10.1124/jpet.107.129486 [Abstract] [Full Text] [PDF]

G. J. Rodrigues, C. B. Restini, C. N. Lunardi, J. E. Moreira, R. G. Lima, R. S. da Silva, and L. M. Bendhack: Caveolae Dysfunction Contributes to Impaired Relaxation Induced by Nitric Oxide Donor in Aorta from Renal Hypertensive Rats
J Pharmacol Exp Ther 2007 323: 831-837. Published online September 4, 2007; 10.1124/jpet.107.127241 [Abstract] [Full Text] [PDF]

Chiari Kojima, Akio Kawakami, Takashi Takei, Kosaku Nitta, and Masayuki Yoshida: Angiotensin-Converting Enzyme Inhibitor Attenuates Monocyte Adhesion to Vascular Endothelium through Modulation of Intracellular Zinc
J Pharmacol Exp Ther 2007 323: 855-860. Published online September 18, 2007; 10.1124/jpet.107.127944 [Abstract] [Full Text] [PDF] [Data Supplement]

Shirley Wee, Jason N. Peart, and John P. Headrick: P2 Purinoceptor-Mediated Cardioprotection in Ischemic-Reperfused Mouse Heart
J Pharmacol Exp Ther 2007 323: 861-867. Published online September 12, 2007; 10.1124/jpet.107.125815 [Abstract] [Full Text] [PDF]

Brett Burstein, Ange Maguy, Robert Clément, Hugues Gosselin, Francine Poulin, Nathalie Ethier, Jean-Claude Tardif, Terence E. Hébert, Angelino Calderone, and Stanley Nattel: Effects of Resveratrol (trans-3,5,4'-Trihydroxystilbene) Treatment on Cardiac Remodeling following Myocardial Infarction
J Pharmacol Exp Ther 2007 323: 916-923. Published online September 17, 2007; 10.1124/jpet.107.127548 [Abstract] [Full Text] [PDF]

Emilie Carrier, Isabelle Brochu, Artur J. de Brum-Fernandes, and Pedro D'Orléans-Juste: The Inducible Nitric-Oxide Synthase Modulates Endothelin-1-Dependent Release of Prostacyclin and Inhibition of Platelet Aggregation ex Vivo in the Mouse
J Pharmacol Exp Ther 2007 323: 972-978. Published online September 20, 2007; 10.1124/jpet.107.125690 [Abstract] [Full Text] [PDF]

CELLULAR AND MOLECULAR:

Robert T. Kinobe, Yanbin Ji, Jason Z. Vlahakis, Roberto Motterlini, James F. Brien, Walter A. Szarek, and Kanji Nakatsu: Effectiveness of Novel Imidazole-Dioxolane Heme Oxygenase Inhibitors in Renal Proximal Tubule Epithelial Cells
J Pharmacol Exp Ther 2007 323: 763-770. Published online August 30, 2007; 10.1124/jpet.107.119800 [Abstract] [Full Text] [PDF]

Kayla C. De Lorme, Marianne K.O. Grant, Meredith J. Noetzel, Sonya B. Polson, and Esam E. El-Fakahany: Long-Term Changes in the Muscarinic M₁ Receptor Induced by Instantaneous Formation of Wash-Resistant Xanomeline-Receptor Complex
J Pharmacol Exp Ther 2007 323: 868-876. Published online September 12, 2007; 10.1124/jpet.107.129940 [Abstract] [Full Text] [PDF]

Gerold Bongers, Kathleen M. Krueger, Thomas R. Miller, John L. Baranowski, Brian R. Estvander, David G. Witte, Marina I. Strakhova, Peter van Meer, Remko A. Bakker, Marlon D. Cowart, Arthur A. Hancock, Timothy A. Esbenshade, and Rob Leurs: An 80-Amino Acid Deletion in the Third Intracellular Loop of a Naturally Occurring Human Histamine H₃ Isoform Confers Pharmacological Differences and Constitutive Activity
J Pharmacol Exp Ther 2007 323: 888-898. Published online September 12, 2007; 10.1124/jpet.107.127639 [Abstract] [Full Text] [PDF]

Mingxiang Liao, Michael K. Pabarcus, YongQiang Wang, Colleen Hefner, David A. Maltby, Katalin F. Medzihradszky, Saida Patricia Salas-Castillo, James Yan, Jacquelyn J. Maher, and Maria Almira Correia: Impaired Dexamethasone-Mediated Induction of Tryptophan 2,3-Dioxygenase in Heme-Deficient Rat Hepatocytes: Translational Control by a Hepatic eIF2 ${alpha}$ Kinase, the Heme-Regulated Inhibitor
J Pharmacol Exp Ther 2007 323: 979-989. Published online August 29, 2007; 10.1124/jpet.107.124602 [Abstract] [Full Text] [PDF] [Data Supplement]

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Raquel Horrillo, Anna Planagumà, Ana González-Périz, Natàlia Ferré, Esther Titos, Rosa Miquel, Marta López-Parra, Jaime L. Masferrer, Vicente Arroyo, and Joan Clària: Comparative Protection against Liver Inflammation and Fibrosis by a Selective Cyclooxygenase-2 Inhibitor and a Nonredox-Type 5-Lipoxygenase Inhibitor
J Pharmacol Exp Ther 2007 323: 778-786. Published online August 31, 2007; 10.1124/jpet.107.128264 [Abstract] [Full Text] [PDF]

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:

Masashi Kitazawa, Yasushi Ohizumi, Yuichi Oike, Takanori Hishinuma, and Seiichi Hashimoto: Angiopoietin-Related Growth Factor Suppresses Gluconeogenesis through the Akt/Forkhead Box Class O1-Dependent Pathway in Hepatocytes
J Pharmacol Exp Ther 2007 323: 787-793. Published online September 5, 2007; 10.1124/jpet.107.127530 [Abstract] [Full Text] [PDF]

Jatinder K. Lamba, Kristine Crews, Stanley Pounds, Erin G. Schuetz, Jessica Gresham, Varsha Gandhi, William Plunkett, Jeffrey Rubnitz, and Raul Ribeiro: Pharmacogenetics of Deoxycytidine Kinase: Identification and Characterization of Novel Genetic Variants
J Pharmacol Exp Ther 2007 323: 935-945. Published online September 12, 2007; 10.1124/jpet.107.128595 [Abstract] [Full Text] [PDF]

NEUROPHARMACOLOGY:

Cameron S. McPherson, Travis Featherby, Elena Krstew, and J. Lawrence Andrew: Quantification of Phosphorylated cAMP-Response Element-Binding Protein Expression throughout the Brain of Amphetamine-Sensitized Rats: Activation of Hypothalamic Orexin A-Containing Neurons
J Pharmacol Exp Ther 2007 323: 805-812. Published online September 18, 2007; 10.1124/jpet.107.125732 [Abstract] [Full Text] [PDF]

Bruno P. Imbimbo, Elda Del Giudice, Davide Colavito, Antonello D'Arrigo, Maurizio Dalle Carbonare, Gino Villetti, Fabrizio Facchinetti, Roberta Volta, Vladimiro Pietrini, Maria F. Baroc, Lutgarde Serneels, Bart De Strooper, and Alberta Leon: 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic Acid (CHF5074), a Novel ${gamma}$ -Secretase Modulator, Reduces Brain $beta$ -Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease without Causing Peripheral Toxicity
J Pharmacol Exp Ther 2007 323: 822-830. Published online September 25, 2007; 10.1124/jpet.107.129007 [Abstract] [Full Text] [PDF]

Allison T. Knoll, Edward G. Meloni, James B. Thomas, F. Ivy Carroll, and William A. Carlezon, Jr.: Anxiolytic-Like Effects of ${kappa}$ -Opioid Receptor Antagonists in Models of Unlearned and Learned Fear in Rats
J Pharmacol Exp Ther 2007 323: 838-845. Published online September 6, 2007; 10.1124/jpet.107.127415 [Abstract] [Full Text] [PDF]

Yi-Chin Lin, Hao-Wei Uang, Rong-Jyh Lin, Ing-Jun Chen, and Yi-Ching Lo: Neuroprotective Effects of Glyceryl Nonivamide against Microglia-Like Cells and 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Human Dopaminergic Neuroblastoma Cells
J Pharmacol Exp Ther 2007 323: 877-887. Published online September 12, 2007; 10.1124/jpet.107.125955 [Abstract] [Full Text] [PDF]

Laura S. Stone, Kelley F. Kitto, James C. Eisenach, Carolyn A. Fairbanks, and George L. Wilcox: ST91 [2-(2,6-Diethylphenylamino)-2-imidazoline Hydrochloride]-Mediated Spinal Antinociception and Synergy with Opioids Persists in the Absence of Functional ${alpha}$ -2A- or ${alpha}$ -2C-Adrenergic Receptors
J Pharmacol Exp Ther 2007 323: 899-906. Published online September 13, 2007; 10.1124/jpet.107.125526 [Abstract] [Full Text] [PDF]

Ryan F. Yoshimura, Derk J. Hogenkamp, Wen Y. Li, Minhtam B. Tran, James D. Belluzzi, Edward R. Whittemore, Frances M. Leslie, and Kelvin W. Gee: Negative Allosteric Modulation of Nicotinic Acetylcholine Receptors Blocks Nicotine Self-Administration in Rats
J Pharmacol Exp Ther 2007 323: 907-915. Published online September 14, 2007; 10.1124/jpet.107.128751 [Abstract] [Full Text] [PDF]

Anni-Maija Linden, Cristina Sandu, M. Isabel Aller, Olga Y. Vekovischeva, Per H. Rosenberg, William Wisden, and Esa R. Korpi: TASK-3 Knockout Mice Exhibit Exaggerated Nocturnal Activity, Impairments in Cognitive Functions, and Reduced Sensitivity to Inhalation Anesthetics
J Pharmacol Exp Ther 2007 323: 924-934. Published online September 17, 2007; 10.1124/jpet.107.129544 [Abstract] [Full Text] [PDF]

Noelia Cañas, Teresa Valero, Mercedes Villarroya, Eulàlia Montell, Josep Vergés, Antonio G. García, and Manuela G. López: Chondroitin Sulfate Protects SH-SY5Y Cells from Oxidative Stress by Inducing Heme Oxygenase-1 via Phosphatidylinositol 3-Kinase/Akt
J Pharmacol Exp Ther 2007 323: 946-953. Published online September 20, 2007; 10.1124/jpet.107.123505 [Abstract] [Full Text] [PDF]

Magí Farré, Sergio Abanades, Pere N. Roset, Ana M. Peiró, Marta Torrens, Bryan O'Mathúna, Mireia Segura, and Rafael de la Torre: Pharmacological Interaction between 3,4-Methylenedioxymethamphetamine (Ecstasy) and Paroxetine: Pharmacological Effects and Pharmacokinetics
J Pharmacol Exp Ther 2007 323: 954-962. Published online September 21, 2007; 10.1124/jpet.107.129056 [Abstract] [Full Text] [PDF]

Hong-Mei Zhang, Hong-Yi Zhou, Shao-Rui Chen, Dinesh Gautam, Jürgen Wess, and Hui-Lin Pan: Control of Glycinergic Input to Spinal Dorsal Horn Neurons by Distinct Muscarinic Receptor Subtypes Revealed Using Knockout Mice
J Pharmacol Exp Ther 2007 323: 963-971. Published online September 18, 2007; 10.1124/jpet.107.127795 [Abstract] [Full Text] [PDF]

Khalid Benamar, Menachem Yondorf, Veronica T. Barreto, Ellen B. Geller, and Martin W. Adler: Deletion of µ-Opioid Receptor in Mice Alters the Development of Acute Neuroinflammation
J Pharmacol Exp Ther 2007 323: 990-994. Published online September 26, 2007; 10.1124/jpet.107.129973 [Abstract] [Full Text] [PDF]

TOXICOLOGY:

Farah D. Khan, Piyush M. Vyas, Anthony A. Gaspari, and Craig K. Svensson: Effect of Arylhydroxylamine Metabolites of Sulfamethoxazole and Dapsone on Stress Signal Expression in Human Keratinocytes
J Pharmacol Exp Ther 2007 323: 771-777. Published online August 31, 2007; 10.1124/jpet.107.126615 [Abstract] [Full Text] [PDF]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Cover Caption:

About the cover: Chronic treatment with CHF5074 in the diet (375 ppm) for 17 weeks does not induce abnormal histological changes in main peripheral organs of aged Tg2576 mice. See the article by Imbimbo et al. on page 822 of this issue.