PERSPECTIVES IN PHARMACOLOGY:

Evgeny Krynetskiy and Patrick McDonnell

Building Individualized Medicine: Prevention of Adverse Reactions to Warfarin Therapy
J Pharmacol Exp Ther 2007 322: 427-434. Published online May 11, 2007; 10.1124/jpet.106.117952 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Lawrence P. Carter, Roland R. Griffiths, Patricia E. Suess, John H. Casada, Christopher L. Wallace, and John D. Roache

Relative Abuse Liability of Indiplon and Triazolam in Humans: A Comparison of Psychomotor, Subjective, and Cognitive Effects
J Pharmacol Exp Ther 2007 322: 749-759. Published online May 14, 2007; 10.1124/jpet.107.119693 [Abstract] [Full Text] [PDF]  

Donna M. Platt, James K. Rowlett, and Roger D. Spealman

Noradrenergic Mechanisms in Cocaine-Induced Reinstatement of Drug Seeking in Squirrel Monkeys
J Pharmacol Exp Ther 2007 322: 894-902. Published online May 15, 2007; 10.1124/jpet.107.121806 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Marta L. Capone, Stefania Tacconelli, Maria G. Sciulli, Paola Anzellotti, Luigia Di Francesco, Gabriele Merciaro, Patrizia Di Gregorio, and Paola Patrignani

Human Pharmacology of Naproxen Sodium
J Pharmacol Exp Ther 2007 322: 453-460. Published online May 1, 2007; 10.1124/jpet.107.122283 [Abstract] [Full Text] [PDF]  

Stephen J. Peterson, Daniel Husney, Adam L. Kruger, Rafal Olszanecki, Francesca Ricci, Luigi F. Rodella, Alessandra Stacchiotti, Rita Rezzani, John A. McClung, Wilbert S. Aronow, Susumu Ikehara, and Nader G. Abraham

Long-Term Treatment with the Apolipoprotein A1 Mimetic Peptide Increases Antioxidants and Vascular Repair in Type I Diabetic Rats
J Pharmacol Exp Ther 2007 322: 514-520. Published online May 8, 2007; 10.1124/jpet.107.119479 [Abstract] [Full Text] [PDF]  

Katsuya Hirano, Namie Nomoto, Mayumi Hirano, Fumi Momota, Akiko Hanada, and Hideo Kanaide

Distinct Ca²⁺ Requirement for NO Production between Proteinase-Activated Receptor 1 and 4 (PAR₁ and PAR₄) in Vascular Endothelial Cells
J Pharmacol Exp Ther 2007 322: 668-677. Published online May 9, 2007; 10.1124/jpet.107.121038 [Abstract] [Full Text] [PDF]  

Rita C. Tostes, Fernanda R. C. Giachini, Fernando S. Carneiro, Romulo Leite, Edward W. Inscho, and R. Clinton Webb

Determination of Adenosine Effects and Adenosine Receptors in Murine Corpus Cavernosum
J Pharmacol Exp Ther 2007 322: 678-685. Published online May 9, 2007; 10.1124/jpet.107.122705 [Abstract] [Full Text] [PDF]  

Matthew L. Bilodeau and Heidi E. Hamm

Regulation of Protease-Activated Receptor (PAR) 1 and PAR4 Signaling in Human Platelets by Compartmentalized Cyclic Nucleotide Actions
J Pharmacol Exp Ther 2007 322: 778-788. Published online May 24, 2007; 10.1124/jpet.107.121830 [Abstract] [Full Text] [PDF] [Data Supplement]   

Danielle Ianzer, Robson Augusto Souza Santos, Gisele Maia Etelvino, Carlos Henrique Xavier, Jerusa de Almeida Santos, Elizabeth Pereira Mendes, Leonor Tapias Machado, Benedito Carlos Prezoto, Vincent Dive, and Antônio Carlos Martins de Camargo

Do the Cardiovascular Effects of Angiotensin-Converting Enzyme (ACE) I Involve ACE-Independent Mechanisms? New Insights from Proline-Rich Peptides of Bothrops jararaca
J Pharmacol Exp Ther 2007 322: 795-805. Published online May 2, 2007; 10.1124/jpet.107.120873 [Abstract] [Full Text] [PDF]  

Katja Steinkamp-Fenske, Larissa Bollinger, Hui Xu, Ying Yao, Sven Horke, Ulrich Förstermann, and Huige Li

Reciprocal Regulation of Endothelial Nitric-Oxide Synthase and NADPH Oxidase by Betulinic Acid in Human Endothelial Cells
J Pharmacol Exp Ther 2007 322: 836-842. Published online May 11, 2007; 10.1124/jpet.107.123356 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

York-Fong Cheung, Zhengyan Kan, Philip Garrett-Engele, Irene Gall, Hannah Murdoch, George S. Baillie, Luiz Miguel Camargo, Jason M. Johnson, Miles D. Houslay, and John C. Castle

PDE4B5, a Novel, Super-Short, Brain-Specific cAMP Phosphodiesterase-4 Variant Whose Isoform-Specifying N-Terminal Region Is Identical to That of cAMP Phosphodiesterase-4D6 (PDE4D6)
J Pharmacol Exp Ther 2007 322: 600-609. Published online May 22, 2007; 10.1124/jpet.107.122218 [Abstract] [Full Text] [PDF]  

Alexandra Zahradníková, Igor Minarovic, and Ivan Zahradník

Competitive and Cooperative Effects of Bay K8644 on the L-Type Calcium Channel Current Inhibition by Calcium Channel Antagonists
J Pharmacol Exp Ther 2007 322: 638-645. Published online May 2, 2007; 10.1124/jpet.107.122176 [Abstract] [Full Text] [PDF] [Data Supplement]   

Lori Badura, Terri Swanson, Wendy Adamowicz, Jessica Adams, Julie Cianfrogna, Katherine Fisher, Janice Holland, Robin Kleiman, Frederick Nelson, Linda Reynolds, Kristin St. Germain, Eric Schaeffer, Barbara Tate, and Jeffrey Sprouse

An Inhibitor of Casein Kinase I Induces Phase Delays in Circadian Rhythms under Free-Running and Entrained Conditions
J Pharmacol Exp Ther 2007 322: 730-738. Published online May 14, 2007; 10.1124/jpet.107.122846 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Natalya M. Kogan, Michael Schlesinger, Maximilian Peters, Gergana Marincheva, Ronen Beeri, and Raphael Mechoulam

A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study
J Pharmacol Exp Ther 2007 322: 646-653. Published online May 3, 2007; 10.1124/jpet.107.120865 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Marcus Winkler, Damian Stephan, Susanne Bieger, Petra Kühner, Felix Wolff, and Ulrich Quast

Testing the Bipartite Model of the Sulfonylurea Receptor Binding Site: Binding of A-, B-, and A + B-Site Ligands
J Pharmacol Exp Ther 2007 322: 701-708. Published online May 10, 2007; 10.1124/jpet.107.123224 [Abstract] [Full Text] [PDF]  

Naoko Misaki, Xia Mao, Yu-Fung Lin, Sechiko Suga, Guo-Hui Li, Qiang Liu, Yongchang Chang, Hai Wang, Makoto Wakui, and Jie Wu

Iptakalim, a Vascular ATP-Sensitive Potassium (K_ATP) Channel Opener, Closes Rat Pancreatic -Cell K_ATP Channels and Increases Insulin Release
J Pharmacol Exp Ther 2007 322: 871-878. Published online May 23, 2007; 10.1124/jpet.107.121129 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Luca Antonioli, Matteo Fornai, Rocchina Colucci, Narcisa Ghisu, Federico Da Settimo, Gianfranco Natale, Olga Kastsiuchenka, Emiliano Duranti, Agostino Virdis, Cristina Vassalle, Concettina La Motta, Laura Mugnaini, Maria Cristina Breschi, Corrado Blandizzi, and Mario Del Taca

Inhibition of Adenosine Deaminase Attenuates Inflammation in Experimental Colitis
J Pharmacol Exp Ther 2007 322: 435-442. Published online May 8, 2007; 10.1124/jpet.107.122762 [Abstract] [Full Text] [PDF]  

Zivar Yousefipour, Hantz Hercule, Luan Truong, Adebayo Oyekan, and Mohammad Newaz

Ciglitazone, a Peroxisome Proliferator-Activated Receptor Inducer, Ameliorates Renal Preglomerular Production and Activity of Angiotensin II and Thromboxane A₂ in Glycerol-Induced Acute Renal Failure
J Pharmacol Exp Ther 2007 322: 461-468. Published online May 9, 2007; 10.1124/jpet.107.122473 [Abstract] [Full Text] [PDF]  

Yasuhiro Nakai, Katsuhisa Inoue, Naoki Abe, Mai Hatakeyama, Kin-ya Ohta, Masaki Otagiri, Yayoi Hayashi, and Hiroaki Yuasa

Functional Characterization of Human Proton-Coupled Folate Transporter/Heme Carrier Protein 1 Heterologously Expressed in Mammalian Cells as a Folate Transporter
J Pharmacol Exp Ther 2007 322: 469-476. Published online May 2, 2007; 10.1124/jpet.107.122606 [Abstract] [Full Text] [PDF]  

Huiling Liu and Jerry M. Farley, Sr.

Prostaglandin E₂ Enhances Acetylcholine-Induced, Ca²⁺-Dependent Ionic Currents in Swine Tracheal Mucous Gland Cells
J Pharmacol Exp Ther 2007 322: 501-513. Published online May 4, 2007; 10.1124/jpet.107.120154 [Abstract] [Full Text] [PDF]  

Shi-Lin Du, Hong Pan, Wei-Yue Lu, Jian Wang, Jian Wu, and Ji-Yao Wang

Cyclic Arg-Gly-Asp Peptide-Labeled Liposomes for Targeting Drug Therapy of Hepatic Fibrosis in Rats
J Pharmacol Exp Ther 2007 322: 560-568. Published online May 17, 2007; 10.1124/jpet.107.122481 [Abstract] [Full Text] [PDF]  

Shingo Sakamoto, Hiroyuki Kusuhara, Kenji Miyata, Hiroyuki Shimaoka, Takushi Kanazu, Yumiko Matsuo, Kohji Nomura, Noboru Okamura, Seijiro Hara, Kazutoshi Horie, Takahiko Baba, and Yuichi Sugiyama

Glucuronidation Converting Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) to a Potent Apical Sodium-Dependent Bile Acid Transporter Inhibitor, Resulting in a Hypocholesterolemic Action
J Pharmacol Exp Ther 2007 322: 610-618. Published online April 30, 2007; 10.1124/jpet.106.116426 [Abstract] [Full Text] [PDF]  

Frederick J. Ehlert, Simon Ahn, Kirk J. Pak, Grace J. Park, Marline S. Sangnil, John A. Tran, and Minoru Matsui

Neuronally Released Acetylcholine Acts on the M₂ Muscarinic Receptor to Oppose the Relaxant Effect of Isoproterenol on Cholinergic Contractions in Mouse Urinary Bladder
J Pharmacol Exp Ther 2007 322: 631-637. Published online May 1, 2007; 10.1124/jpet.107.121756 [Abstract] [Full Text] [PDF]  

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA:

Waldemar Gonsiorek, Xuedong Fan, David Hesk, James Fossetta, Hongchen Qiu, James Jakway, Motasim Billah, Michael Dwyer, Jianhua Chao, Gregory Deno, Art Taveras, Daniel J. Lundell, and R. William Hipkin

Pharmacological Characterization of Sch527123, a Potent Allosteric CXCR1/CXCR2 Antagonist
J Pharmacol Exp Ther 2007 322: 477-485. Published online May 11, 2007; 10.1124/jpet.106.118927 [Abstract] [Full Text] [PDF]  

Richard W. Chapman, Michael Minnicozzi, Chander S. Celly, Jonathan E. Phillips, Ted T. Kung, R. William Hipkin, Xuedong Fan, Diane Rindgen, Gregory Deno, Richard Bond, Waldemar Gonsiorek, Motasim M. Billah, Jay S. Fine, and John A. Hey

A Novel, Orally Active CXCR1/2 Receptor Antagonist, Sch527123, Inhibits Neutrophil Recruitment, Mucus Production, and Goblet Cell Hyperplasia in Animal Models of Pulmonary Inflammation
J Pharmacol Exp Ther 2007 322: 486-493. Published online May 11, 2007; 10.1124/jpet.106.119040 [Abstract] [Full Text] [PDF]  

Naoki Kobayashi, Hitomi Kobayashi, Leo Gu, Thomas Malefyt, and Teruna J. Siahaan

Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor
J Pharmacol Exp Ther 2007 322: 879-886. Published online May 23, 2007; 10.1124/jpet.107.123257 [Abstract] [Full Text] [PDF] [Data Supplement]   

Karen Santora, Cordelia Rasa, Denise Visco, Bernard G. Steinetz, and Carol A. Bagnell

Antiarthritic Effects of Relaxin, in Combination with Estrogen, in Rat Adjuvant-Induced Arthritis
J Pharmacol Exp Ther 2007 322: 887-893. Published online May 25, 2007; 10.1124/jpet.107.122903 [Abstract] [Full Text] [PDF]  

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:

Yuan Ji, Irene Moon, Jelena Zlatkovic, Oreste E. Salavaggione, Bianca A. Thomae, Bruce W. Eckloff, Eric D. Wieben, Daniel J. Schaid, and Richard M. Weinshilboum

Human Hydroxysteroid Sulfotransferase SULT2B1 Pharmacogenomics: Gene Sequence Variation and Functional Genomics
J Pharmacol Exp Ther 2007 322: 529-540. Published online May 11, 2007; 10.1124/jpet.107.122895 [Abstract] [Full Text] [PDF] [Data Supplement]   

Ying Chen, Shuzhong Zhang, Marco Sorani, and Kathleen M. Giacomini

Transport of Paraquat by Human Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Family
J Pharmacol Exp Ther 2007 322: 695-700. Published online May 10, 2007; 10.1124/jpet.107.123554 [Abstract] [Full Text] [PDF]  

Gabor Kottra and Hannelore Daniel

Flavonoid Glycosides Are Not Transported by the Human Na⁺/Glucose Transporter When Expressed in Xenopus laevis Oocytes, but Effectively Inhibit Electrogenic Glucose Uptake
J Pharmacol Exp Ther 2007 322: 829-835. Published online May 10, 2007; 10.1124/jpet.107.124040 [Abstract] [Full Text] [PDF]  

Hao Sun, William J. Ehlhardt, Palaniappan Kulanthaivel, Diane L. Lanza, Christopher A. Reilly, and Garold S. Yost

Dehydrogenation of Indoline by Cytochrome P450 Enzymes: A Novel "Aromatase" Process
J Pharmacol Exp Ther 2007 322: 843-851. Published online May 14, 2007; 10.1124/jpet.107.121723 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Laxmikant S. Deshpande, David D. Limbrick, Jr., Sompong Sombati, and Robert J. DeLorenzo

Activation of a Novel Injury-Induced Calcium-Permeable Channel That Plays a Key Role in Causing Extended Neuronal Depolarization and Initiating Neuronal Death in Excitotoxic Neuronal Injury
J Pharmacol Exp Ther 2007 322: 443-452. Published online May 4, 2007; 10.1124/jpet.107.123182 [Abstract] [Full Text] [PDF]  

Irina Katz, Jinsook Kim, Karen Gale, and Alexei Kondratyev

Effects of Lamotrigine Alone and in Combination with MK-801, Phenobarbital, or Phenytoin on Cell Death in the Neonatal Rat Brain
J Pharmacol Exp Ther 2007 322: 494-500. Published online May 4, 2007; 10.1124/jpet.107.123133 [Abstract] [Full Text] [PDF]  

Christine L. Keogh, Shan Ping Yu, and Ling Wei

The Effect of Recombinant Human Erythropoietin on Neurovasculature Repair after Focal Ischemic Stroke in Neonatal Rats
J Pharmacol Exp Ther 2007 322: 521-528. Published online May 9, 2007; 10.1124/jpet.107.121392 [Abstract] [Full Text] [PDF]  

Karunya K. Kandimalla, Thomas M. Wengenack, Geoffry L. Curran, Emily J. Gilles, and Joseph F. Poduslo

Pharmacokinetics and Amyloid Plaque Targeting Ability of a Novel Peptide-Based Magnetic Resonance Contrast Agent in Wild-Type and Alzheimer's Disease Transgenic Mice
J Pharmacol Exp Ther 2007 322: 541-549. Published online May 15, 2007; 10.1124/jpet.107.119883 [Abstract] [Full Text] [PDF]  

Marcel Gehlhaus, Nina Schmitt, Benedikt Volk, and Ralf P. Meyer

Antiepileptic Drugs Affect Neuronal Androgen Signaling via a Cytochrome P450-Dependent Pathway
J Pharmacol Exp Ther 2007 322: 550-559. Published online May 15, 2007; 10.1124/jpet.107.120303 [Abstract] [Full Text] [PDF]  

Jun Song, Guofu Shen, L. John Greenfield, Jr., and Elizabeth I. Tietz

Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing -Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptors in Hippocampal CA1 Neurons
J Pharmacol Exp Ther 2007 322: 569-581. Published online May 17, 2007; 10.1124/jpet.107.121798 [Abstract] [Full Text] [PDF] [Data Supplement]   

Takuya Nakayama, Naoaki Harada, Miki Asano, Norikazu Nomura, Takayuki Saito, Akira Mishima, and Kenji Okajima

Atrial Natriuretic Peptide Reduces Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Enhancing Sensory Neuron Activation
J Pharmacol Exp Ther 2007 322: 582-590. Published online May 23, 2007; 10.1124/jpet.107.120725 [Abstract] [Full Text] [PDF]  

Silvia Lorrio, Mónica Sobrado, Esperanza Arias, José M. Roda, Antonio G. García, and Manuela G. López

Galantamine Postischemia Provides Neuroprotection and Memory Recovery against Transient Global Cerebral Ischemia in Gerbils
J Pharmacol Exp Ther 2007 322: 591-599. Published online May 25, 2007; 10.1124/jpet.107.122747 [Abstract] [Full Text] [PDF]  

Jon E. Hawkinson, Balazs G. Szoke, Albert W. Garofalo, Dennis S. Hom, Hongbing Zhang, Mark Dreyer, Juri Y. Fukuda, Linda Chen, Bhushan Samant, Stellanie Simmonds, Karla P. Zeitz, Angie Wadsworth, Anna Liao, Raymond A. Chavez, Wes Zmolek, Lany Ruslim, Michael P. Bova, Ryan Holcomb, Eduardo R. Butelman, Mei-Chuan Ko, and Annika B. Malmberg

Pharmacological, Pharmacokinetic, and Primate Analgesic Efficacy Profile of the Novel Bradykinin B₁ Receptor Antagonist ELN441958
J Pharmacol Exp Ther 2007 322: 619-630. Published online April 30, 2007; 10.1124/jpet.107.120352 [Abstract] [Full Text] [PDF]  

Nai-Jiang Liu, Hans von Gizycki, and Alan R. Gintzler

Sexually Dimorphic Recruitment of Spinal Opioid Analgesic Pathways by the Spinal Application of Morphine
J Pharmacol Exp Ther 2007 322: 654-660. Published online May 8, 2007; 10.1124/jpet.107.123620 [Abstract] [Full Text] [PDF]  

Susan P. Hume, Anne R. Lingford-Hughes, Valerie Nataf, Ella Hirani, Rabia Ahmad, Andrew N. Davies, and David J. Nutt

Low Sensitivity of the Positron Emission Tomography Ligand [¹¹C]Diprenorphine to Agonist Opiates
J Pharmacol Exp Ther 2007 322: 661-667. Published online May 8, 2007; 10.1124/jpet.107.121749 [Abstract] [Full Text] [PDF]  

Kazunari Nakao, Akio Murase, Hiroyuki Ohshiro, Takako Okumura, Kana Taniguchi, Yoko Murata, Masatoshi Masuda, Tomoki Kato, Yoshiyuki Okumura, and Junji Takada

CJ-023,423, a Novel, Potent and Selective Prostaglandin EP₄ Receptor Antagonist with Antihyperalgesic Properties
J Pharmacol Exp Ther 2007 322: 686-694. Published online May 10, 2007; 10.1124/jpet.107.122010 [Abstract] [Full Text] [PDF]  

Thierry Bordet, Bruno Buisson, Magali Michaud, Cyrille Drouot, Pascale Galéa, Pierre Delaage, Natalia P. Akentieva, Alex S. Evers, Douglas F. Covey, Mariano A. Ostuni, Jean-Jacques Lacapère, Charbel Massaad, Michael Schumacher, Esther-Marie Steidl, Delphine Maux, Michel Delaage, Christopher E. Henderson, and Rebecca M. Pruss

Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
J Pharmacol Exp Ther 2007 322: 709-720. Published online May 11, 2007; 10.1124/jpet.107.123000 [Abstract] [Full Text] [PDF] [Data Supplement]   

Michela Giustizieri, Maria Letizia Cucchiaroni, Ezia Guatteo, Giorgio Bernardi, Nicola B. Mercuri, and Nicola Berretta

Memantine Inhibits ATP-Dependent K⁺ Conductances in Dopamine Neurons of the Rat Substantia Nigra Pars Compacta
J Pharmacol Exp Ther 2007 322: 721-729. Published online May 11, 2007; 10.1124/jpet.107.122036 [Abstract] [Full Text] [PDF]  

Ahmed A. Othman, Amy Hauck Newman, and Natalie D. Eddington

Applicability of the Dopamine and Rate Hypotheses in Explaining the Differences in Behavioral Pharmacology of the Chloro-Benztropine Analogs: Studies Conducted Using Intracerebral Microdialysis and Population Pharmacodynamic Modeling
J Pharmacol Exp Ther 2007 322: 760-769. Published online May 22, 2007; 10.1124/jpet.107.123315 [Abstract] [Full Text] [PDF]  

Wei V. Zhang, Iqbal Ramzan, and Michael Murray

Impaired Microsomal Oxidation of the Atypical Antipsychotic Agent Clozapine in Hepatic Steatosis
J Pharmacol Exp Ther 2007 322: 770-777. Published online May 23, 2007; 10.1124/jpet.107.124024 [Abstract] [Full Text] [PDF]  

Sean D. McKenna, Georg Feger, Christie Kelton, Meijia Yang, Vittoria Ardissone, Rocco Cirillo, Pierre-Alain Vitte, Xuliang Jiang, and Robert K. Campbell

Tumor Necrosis Factor (TNF)-Soluble High-Affinity Receptor Complex as a TNF Antagonist
J Pharmacol Exp Ther 2007 322: 822-828. Published online May 10, 2007; 10.1124/jpet.107.119875 [Abstract] [Full Text] [PDF]  

Luis R. Gardell, Kimberly E. Vanover, Linda Pounds, Robert W. Johnson, Richard Barido, Gary T. Anderson, Isaac Veinbergs, Agnete Dyssegaard, Per Brunmark, Ali Tabatabaei, Robert E. Davis, Mark R. Brann, Uli Hacksell, and Douglas W. Bonhaus

ACP-103, a 5-Hydroxytryptamine 2A Receptor Inverse Agonist, Improves the Antipsychotic Efficacy and Side-Effect Profile of Haloperidol and Risperidone in Experimental Models
J Pharmacol Exp Ther 2007 322: 862-870. Published online May 22, 2007; 10.1124/jpet.107.121715 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

C. Thetford Smothers and John J. Woodward

Pharmacological Characterization of Glycine-Activated Currents in HEK 293 Cells Expressing N-Methyl-D-aspartate NR1 and NR3 Subunits
J Pharmacol Exp Ther 2007 322: 739-748. Published online May 14, 2007; 10.1124/jpet.107.123836 [Abstract] [Full Text] [PDF]  

Leela Cherian, J. Clay Goodman, and Claudia Robertson

Neuroprotection with Erythropoietin Administration Following Controlled Cortical Impact Injury in Rats
J Pharmacol Exp Ther 2007 322: 789-794. Published online April 30, 2007; 10.1124/jpet.107.119628 [Abstract] [Full Text] [PDF]  

Xi-Chun Zhang, Andrew M. Strassman, Rami Burstein, and Dan Levy

Sensitization and Activation of Intracranial Meningeal Nociceptors by Mast Cell Mediators
J Pharmacol Exp Ther 2007 322: 806-812. Published online May 4, 2007; 10.1124/jpet.107.123745 [Abstract] [Full Text] [PDF]  

Kenneth T. Sykes, Stephanie R. White, Robert W. Hurley, Hirokazu Mizoguchi, Leon F. Tseng, and Donna L. Hammond

Mechanisms Responsible for the Enhanced Antinociceptive Effects of µ-Opioid Receptor Agonists in the Rostral Ventromedial Medulla of Male Rats with Persistent Inflammatory Pain
J Pharmacol Exp Ther 2007 322: 813-821. Published online May 9, 2007; 10.1124/jpet.107.121954 [Abstract] [Full Text] [PDF]  

Xiaomin Deng, James P. Luyendyk, Wei Zou, Jingtao Lu, Ernst Malle, Patricia E. Ganey, and Robert A. Roth

Neutrophil Interaction with the Hemostatic System Contributes to Liver Injury in Rats Cotreated with Lipopolysaccharide and Ranitidine
J Pharmacol Exp Ther 2007 322: 852-861. Published online May 15, 2007; 10.1124/jpet.107.122069 [Abstract] [Full Text] [PDF]  

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