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November 2006; 319 (2)   [Index by Author]  [Cover Caption]
      Down PERSPECTIVES IN PHARMACOLOGY
      Down BEHAVIORAL PHARMACOLOGY
      Down CARDIOVASCULAR
      Down CELLULAR AND MOLECULAR
      Down CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
      Down ENDOCRINE AND DIABETES
      Down GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
      Down INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA
      Down METABOLISM, TRANSPORT, AND PHARMACOGENOMICS
      Down NEUROPHARMACOLOGY
      Down TOXICOLOGY
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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |
To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

PERSPECTIVES IN PHARMACOLOGY:Back

S. S. Negus, T. W. Vanderah, M. R. Brandt, E. J. Bilsky, L. Becerra, and D. Borsook
Preclinical Assessment of Candidate Analgesic Drugs: Recent Advances and Future Challenges
J Pharmacol Exp Ther 2006 319: 507-514. Published online June 2, 2006; 10.1124/jpet.106.106377 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:Back

Howard C. Becker and Alicia M. Baros
Effect of Duration and Pattern of Chronic Ethanol Exposure on Tolerance to the Discriminative Stimulus Effects of Ethanol in C57BL/6J Mice
J Pharmacol Exp Ther 2006 319: 871-878. Published online August 16, 2006; 10.1124/jpet.106.108795 [Abstract] [Full Text] [PDF]  

Nathalie Turle-Lorenzo, Béatrice Maurin, Carole Puma, Claire Chezaubernard, Philippe Morain, Christelle Baunez, André Nieoullon, and Marianne Amalric
The Dopamine Agonist Piribedil with L-DOPA Improves Attentional Dysfunction: Relevance for Parkinson's Disease
J Pharmacol Exp Ther 2006 319: 914-923. Published online August 18, 2006; 10.1124/jpet.106.109207 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:Back

Sandra Donnini, Raffaella Solito, Antonio Giachetti, Harris J. Granger, Marina Ziche, and Lucia Morbidelli
Fibroblast Growth Factor-2 Mediates Angiotensin-Converting Enzyme Inhibitor-Induced Angiogenesis in Coronary Endothelium
J Pharmacol Exp Ther 2006 319: 515-522. Published online July 25, 2006; 10.1124/jpet.106.108803 [Abstract] [Full Text] [PDF]  

Anastasia Pyriochou, Dimitris Beis, Vasiliki Koika, Christos Potytarchou, Evangelia Papadimitriou, Zongmin Zhou, and Andreas Papapetropoulos
Soluble Guanylyl Cyclase Activation Promotes Angiogenesis
J Pharmacol Exp Ther 2006 319: 663-671. Published online August 29, 2006; 10.1124/jpet.106.108878 [Abstract] [Full Text] [PDF] [Data Supplement]   

Beatriz Pozo-Navas, Heike Stessel, Gerald Wölkart, and Friedrich Brunner
Role of Myocardial Nitric Oxide in Diabetic Ischemia-Reperfusion Dysfunction: Studies in Mice with Myocyte-Specific Overexpression of Endothelial Nitric-Oxide Synthase
J Pharmacol Exp Ther 2006 319: 729-738. Published online July 20, 2006; 10.1124/jpet.106.107854 [Abstract] [Full Text] [PDF]  

Christopher K. Taylor, D. David Smith, Martin Hulce, and Peter W. Abel
Pharmacological Characterization of Novel {alpha}-Calcitonin Gene-Related Peptide (CGRP) Receptor Peptide Antagonists That Are Selective for Human CGRP Receptors
J Pharmacol Exp Ther 2006 319: 749-757. Published online July 27, 2006; 10.1124/jpet.106.108316 [Abstract] [Full Text] [PDF]  

Ruslan Tiniakov and Karie E. Scrogin
The Serotonin 5-Hydroxytryptaphan1A Receptor Agonist, (+)8-Hydroxy-2-(di-n-propylamino)-tetralin, Stimulates Sympathetic-Dependent Increases in Venous Tone during Hypovolemic Shock
J Pharmacol Exp Ther 2006 319: 776-782. Published online August 2, 2006; 10.1124/jpet.106.108944 [Abstract] [Full Text] [PDF]  

Javier Angulo, Pedro Cuevas, Argentina Fernández, Antonio Allona, Ignacio Moncada, Antonio Martín-Morales, José María La Fuente, and Iñigo Sáenz de Tejada
Enhanced Thromboxane Receptor-Mediated Responses and Impaired Endothelium-Dependent Relaxation in Human Corpus Cavernosum from Diabetic Impotent Men: Role of Protein Kinase C Activity
J Pharmacol Exp Ther 2006 319: 783-789. Published online August 3, 2006; 10.1124/jpet.106.108597 [Abstract] [Full Text] [PDF]  

Joachim R. Ehrlich, Christin Hoche, Pierre Coutu, Christiane Metz-Weidmann, Werner Dittrich, Stefan H. Hohnloser, Stanley Nattel, and Heinz Gögelein
Properties of a Time-Dependent Potassium Current in Pig Atrium: Evidence for a Role of Kv1.5 in Repolarization
J Pharmacol Exp Ther 2006 319: 898-906. Published online August 17, 2006; 10.1124/jpet.106.110080 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:Back

Chien-Lun Chen, Jennifer Sung, Michael Cohen, Wasim H. Chowdhury, Markus D. Sachs, Ying Li, Yegappan Lakshmanan, Benjamin Y. M. Yung, Shawn E. Lupold, and Ronald Rodriguez
Valproic Acid Inhibits Invasiveness in Bladder Cancer but Not in Prostate Cancer Cells
J Pharmacol Exp Ther 2006 319: 533-542. Published online July 25, 2006; 10.1124/jpet.106.106658 [Abstract] [Full Text] [PDF]  

Virginia Probin, Yong Wang, Aiping Bai, and Daohong Zhou
Busulfan Selectively Induces Cellular Senescence but Not Apoptosis in WI38 Fibroblasts via a p53-Independent but Extracellular Signal-Regulated Kinase-p38 Mitogen-Activated Protein Kinase-Dependent Mechanism
J Pharmacol Exp Ther 2006 319: 551-560. Published online August 1, 2006; 10.1124/jpet.106.107771 [Abstract] [Full Text] [PDF]  

JangJa Hong, Yasuhiro Nakano, Aya Yokomakura, Kenji Ishihara, Soonjoo Kim, Young-Sook Kang, and Kazuo Ohuchi
Nitric Oxide Production by the Vacuolar-Type (H+)-ATPase Inhibitors Bafilomycin A1 and Concanamycin A and Its Possible Role in Apoptosis in RAW 264.7 Cells
J Pharmacol Exp Ther 2006 319: 672-681. Published online August 8, 2006; 10.1124/jpet.106.109280 [Abstract] [Full Text] [PDF]  

Terry Kenakin, Stephen Jenkinson, and Christian Watson
Determining the Potency and Molecular Mechanism of Action of Insurmountable Antagonists
J Pharmacol Exp Ther 2006 319: 710-723. Published online July 20, 2006; 10.1124/jpet.106.107375 [Abstract] [Full Text] [PDF]  

Supriya A. Bavadekar, Guoyi Ma, Suni M. Mustafa, Bob M. Moore, Duane D. Miller, and Dennis R. Feller
Tethered Yohimbine Analogs as Selective Human {alpha}2C-Adrenergic Receptor Ligands
J Pharmacol Exp Ther 2006 319: 739-748. Published online July 27, 2006; 10.1124/jpet.106.105981 [Abstract] [Full Text] [PDF]  

Vicenta Salvador-Recatala, Yonjung Kim, Elena Zaks-Makhina, and Edwin S. Levitan
Voltage-Gated K+ Channel Block by Catechol Derivatives: Defining Nonselective and Selective Pharmacophores
J Pharmacol Exp Ther 2006 319: 758-764. Published online July 31, 2006; 10.1124/jpet.106.107607 [Abstract] [Full Text] [PDF]  

Yong Chen, Chongguang Chen, Yulin Wang, and Lee-Yuan Liu-Chen
Ligands Regulate Cell Surface Level of the Human {kappa} Opioid Receptor by Activation-Induced Down-Regulation and Pharmacological Chaperone-Mediated Enhancement: Differential Effects of Nonpeptide and Peptide Agonists
J Pharmacol Exp Ther 2006 319: 765-775. Published online August 1, 2006; 10.1124/jpet.106.107987 [Abstract] [Full Text] [PDF]  

Rodolfo Bianchini, Giuseppe Nocentini, Ludovic Tibor Krausz, Katia Fettucciari, Stefano Coaccioli, Simona Ronchetti, and Carlo Riccardi
Modulation of Pro- and Antiapoptotic Molecules in Double-Positive (CD4+CD8+) Thymocytes following Dexamethasone Treatment
J Pharmacol Exp Ther 2006 319: 887-897. Published online August 16, 2006; 10.1124/jpet.106.108480 [Abstract] [Full Text] [PDF] [Data Supplement] [Erratum]   

Haoyu Zeng, Irina M. Lozinskaya, Zuojun Lin, Robert N. Willette, David P. Brooks, and Xiaoping Xu
Mallotoxin Is a Novel Human Ether-a-go-go-Related Gene (hERG) Potassium Channel Activator
J Pharmacol Exp Ther 2006 319: 957-962. Published online August 23, 2006; 10.1124/jpet.106.110593 [Abstract] [Full Text] [PDF]  

Anne M. Heacock, Daniel J. Foster, and Stephen K. Fisher
Prostanoid Receptors Regulate the Volume-Sensitive Efflux of Osmolytes from Murine Fibroblasts via a Cyclic AMP-Dependent Mechanism
J Pharmacol Exp Ther 2006 319: 963-971. Published online August 25, 2006; 10.1124/jpet.106.109496 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:Back

Pål K. Selbo, Anette Weyergang, Anette Bonsted, Stephen G. Bown, and Kristian Berg
Photochemical Internalization of Therapeutic Macromolecular Agents: A Novel Strategy to Kill Multidrug-Resistant Cancer Cells
J Pharmacol Exp Ther 2006 319: 604-612. Published online August 10, 2006; 10.1124/jpet.106.109165 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:Back

H. Alec Ross, Petra J. van Gurp, Jacques J. Willemsen, Jacques W. M. Lenders, Cees J. Tack, and Fred C. G. J. Sweep
Transport within the Interstitial Space, Rather Than Membrane Permeability, Determines Norepinephrine Recovery in Microdialysis
J Pharmacol Exp Ther 2006 319: 840-846. Published online August 10, 2006; 10.1124/jpet.106.109710 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:Back

Carolin Daniel, Heinfried H. Radeke, Nico A. Sartory, Nadine Zahn, Ulrich Zuegel, Andreas Steinmeyer, and Jürgen Stein
The New Low Calcemic Vitamin D Analog 22-Ene-25-Oxa-Vitamin D Prominently Ameliorates T Helper Cell Type 1-Mediated Colitis in Mice
J Pharmacol Exp Ther 2006 319: 622-631. Published online August 16, 2006; 10.1124/jpet.106.107599 [Abstract] [Full Text] [PDF]  

Hayato Kurata, Toshihide Fujii, Hidenobu Tsutsui, Tomoaki Katayama, Mamoru Ohkita, Masanori Takaoka, Nobuo Tsuruoka, Yoshinobu Kiso, Yukihiro Ohno, Yoshihide Fujisawa, Takatoshi Shokoji, Akira Nishiyama, Youichi Abe, and Yasuo Matsumura
Renoprotective Effects of l-Carnosine on Ischemia/Reperfusion-Induced Renal Injury in Rats
J Pharmacol Exp Ther 2006 319: 640-647. Published online August 17, 2006; 10.1124/jpet.106.110122 [Abstract] [Full Text] [PDF]  

Paola Nieri, Cinzia Martinelli, Corrado Blandizzi, Nunzia Bernardini, Rosamiria Greco, Chiara Ippolito, Mario Del Tacca, and Maria Cristina Breschi
Role of Cyclooxygenase Isoforms and Nitric-Oxide Synthase in the Modulation of Tracheal Motor Responsiveness in Normal and Antigen-Sensitized Guinea Pigs
J Pharmacol Exp Ther 2006 319: 648-656. Published online August 22, 2006; 10.1124/jpet.106.102475 [Abstract] [Full Text] [PDF]  

Pedro J. Gomez-Pinilla, Cristina Camello-Almaraz, Rosario Moreno, Pedro J. Camello, and María J. Pozo
Melatonin Treatment Reverts Age-Related Changes in Guinea Pig Gallbladder Neuromuscular Transmission and Contractility
J Pharmacol Exp Ther 2006 319: 847-856. Published online August 11, 2006; 10.1124/jpet.106.109256 [Abstract] [Full Text] [PDF]  

Samuel A. Mantey, Nieves Gonzalez, Michael Schumann, Tapas K. Pradhan, Lin Shen, David H. Coy, and Robert T. Jensen
Identification of Bombesin Receptor Subtype-Specific Ligands: Effect of N-Methyl Scanning, Truncation, Substitution, and Evaluation of Putative Reported Selective Ligands
J Pharmacol Exp Ther 2006 319: 980-989. Published online August 30, 2006; 10.1124/jpet.106.107011 [Abstract] [Full Text] [PDF]  

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA:Back

Sum Yee Leung, Akio Niimi, Alistair Noble, Timothy Oates, Alison S. Williams, Satyanarayana Medicherla, Andrew A. Protter, and Kian Fan Chung
Effect of Transforming Growth Factor-beta Receptor I Kinase Inhibitor 2,4-Disubstituted Pteridine (SD-208) in Chronic Allergic Airway Inflammation and Remodeling
J Pharmacol Exp Ther 2006 319: 586-594. Published online August 3, 2006; 10.1124/jpet.106.109314 [Abstract] [Full Text] [PDF]  

Yun-Feng Fu, Yi-Na Zhu, Jia Ni, Xiang-Gen Zhong, Wei Tang, Yu-Dan Re, Li-Ping Shi, Jin Wan, Yi-Fu Yang, Chong Yuan, Fa-Jun Nan, Brian R. Lawson, and Jian-Ping Zuo
A Reversible S-Adenosyl-L-Homocysteine Hydrolase Inhibitor Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting T Cell Activation
J Pharmacol Exp Ther 2006 319: 799-808. Published online August 16, 2006; 10.1124/jpet.106.107185 [Abstract] [Full Text] [PDF] [Data Supplement]   

Soledad Negrotto, Elisa Malaver, María Eugenia Alvarez, Natalia Pacienza, Lina Paola D'Atri, Roberto Gabriel Pozner, Ricardo Martín Gómez, and Mirta Schattner
Aspirin and Salicylate Suppress Polymorphonuclear Apoptosis Delay Mediated by Proinflammatory Stimuli
J Pharmacol Exp Ther 2006 319: 972-979. Published online August 25, 2006; 10.1124/jpet.106.109389 [Abstract] [Full Text] [PDF]  

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:Back

Andrea Gaedigk, Darren W. Baker, Rheem A. Totah, Roger Gaedigk, Robin E. Pearce, Carrie A. Vyhlidal, Darryl C. Zeldin, and J. Steven Leeder
Variability of CYP2J2 Expression in Human Fetal Tissues
J Pharmacol Exp Ther 2006 319: 523-532. Published online July 25, 2006; 10.1124/jpet.106.109215 [Abstract] [Full Text] [PDF]  

Elisabet Gullberg, Åsa V. Keita, Sa'ad Y. Salim, Margaretha Andersson, Karin D. Caldwell, Johan D. Söderholm, and Per Artursson
Identification of Cell Adhesion Molecules in the Human Follicle-Associated Epithelium That Improve Nanoparticle Uptake into the Peyer's Patches
J Pharmacol Exp Ther 2006 319: 632-639. Published online August 16, 2006; 10.1124/jpet.106.107847 [Abstract] [Full Text] [PDF]  

Stefan Heckl and Ulrich Vogel
Nuclear Trafficking of a Gadolinium Conjugate in Nude Mice Xenografted with Human LN-229 Glioma
J Pharmacol Exp Ther 2006 319: 657-662. Published online August 22, 2006; 10.1124/jpet.106.109868 [Abstract] [Full Text] [PDF] [Data Supplement]   

Masahiro Itoh, Miki Nakajima, Eriko Higashi, Ryoko Yoshida, Kiyoshi Nagata, Yasushi Yamazoe, and Tsuyoshi Yokoi
Induction of Human CYP2A6 Is Mediated by the Pregnane X Receptor with Peroxisome Proliferator-Activated Receptor-{gamma} Coactivator 1{alpha}
J Pharmacol Exp Ther 2006 319: 693-702. Published online July 20, 2006; 10.1124/jpet.106.107573 [Abstract] [Full Text] [PDF]  

Jennifer A. Loehle, Valerie Cornish, Larissa Wakefield, Mark A. Doll, Jason R. Neale, Yu Zang, Edith Sim, and David W. Hein
N-Acetyltransferase (Nat) 1 and 2 Expression in Nat2 Knockout Mice
J Pharmacol Exp Ther 2006 319: 724-728. Published online July 20, 2006; 10.1124/jpet.106.108662 [Abstract] [Full Text] [PDF]  

Antonin Libra, Cristina Fernetti, Vito Lorusso, Massimo Visigalli, Pier Lucio Anelli, Frantisek Staud, Claudio Tiribelli, and Lorella Pascolo
Molecular Determinants in the Transport of a Bile Acid-Derived Diagnostic Agent in Tumoral and Nontumoral Cell Lines of Human Liver
J Pharmacol Exp Ther 2006 319: 809-817. Published online August 8, 2006; 10.1124/jpet.106.106591 [Abstract] [Full Text] [PDF]  

Huadong Sun, Lichuan Liu, and K. Sandy Pang
Increased Estrogen Sulfation of Estradiol 17beta-D-Glucuronide in Metastatic Tumor Rat Livers
J Pharmacol Exp Ther 2006 319: 818-831. Published online August 8, 2006; 10.1124/jpet.106.108860 [Abstract] [Full Text] [PDF]  

Justine L. Lam, Sarah B. Shugarts, Hideaki Okochi, and Leslie Z. Benet
Elucidating the Effect of Final-Day Dosing of Rifampin in Induction Studies on Hepatic Drug Disposition and Metabolism
J Pharmacol Exp Ther 2006 319: 864-870. Published online August 11, 2006; 10.1124/jpet.106.108282 [Abstract] [Full Text] [PDF]  

Atsushi Yonezawa, Satohiro Masuda, Sachiko Yokoo, Toshiya Katsura, and Ken-ichi Inui
Cisplatin and Oxaliplatin, but Not Carboplatin and Nedaplatin, Are Substrates for Human Organic Cation Transporters (SLC22A1–3 and Multidrug and Toxin Extrusion Family)
J Pharmacol Exp Ther 2006 319: 879-886. Published online August 16, 2006; 10.1124/jpet.106.110346 [Abstract] [Full Text] [PDF]  

Tomoko Nakatani-Freshwater, Mariana Babayeva, Aruna Dontabhaktuni, and David R. Taft
Effects of Trimethoprim on the Clearance of Apricitabine, a Deoxycytidine Analog Reverse Transcriptase Inhibitor, and Lamivudine in the Isolated Perfused Rat Kidney
J Pharmacol Exp Ther 2006 319: 941-947. Published online August 22, 2006; 10.1124/jpet.106.108522 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:Back

Marianna E. Jung, Andrew M. Wilson, and James W. Simpkins
A Nonfeminizing Estrogen Analog Protects against Ethanol Withdrawal Toxicity in Immortalized Hippocampal Cells
J Pharmacol Exp Ther 2006 319: 543-550. Published online July 27, 2006; 10.1124/jpet.106.103630 [Abstract] [Full Text] [PDF]  

Bertha K. Madras, Zhihua Xie, Zhicheng Lin, Amy Jassen, Helen Panas, Laurie Lynch, Ryan Johnson, Eli Livni, Thomas J. Spencer, Ali A. Bonab, Gregory M. Miller, and Alan J. Fischman
Modafinil Occupies Dopamine and Norepinephrine Transporters in Vivo and Modulates the Transporters and Trace Amine Activity in Vitro
J Pharmacol Exp Ther 2006 319: 561-569. Published online August 2, 2006; 10.1124/jpet.106.106583 [Abstract] [Full Text] [PDF]  

Bertha K. Madras, Michele A. Fahey, Martin Goulet, Zhicheng Lin, Jacob Bendor, Claudia Goodrich, Peter C. Meltzer, David R. Elmaleh, Eli Livni, Ali A. Bonab, and Alan J. Fischman
Dopamine Transporter (DAT) Inhibitors Alleviate Specific Parkinsonian Deficits in Monkeys: Association with DAT Occupancy in Vivo
J Pharmacol Exp Ther 2006 319: 570-585. Published online August 2, 2006; 10.1124/jpet.106.105312 [Abstract] [Full Text] [PDF]  

Sufen Yang, Jun Yang, Zhengqin Yang, Posee Chen, Alison Fraser, Wei Zhang, Hao Pang, Xi Gao, Belinda Wilson, Jau-Shyong Hong, and Michelle L. Block
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) 38 and PACAP4–6 Are Neuroprotective through Inhibition of NADPH Oxidase: Potent Regulators of Microglia-Mediated Oxidative Stress
J Pharmacol Exp Ther 2006 319: 595-603. Published online August 4, 2006; 10.1124/jpet.106.102236 [Abstract] [Full Text] [PDF]  

Ashraf Yassen, Jingmin Kan, Erik Olofsen, Ernst Suidgeest, Albert Dahan, and Meindert Danhof
Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling of the Respiratory-Depressant Effect of Buprenorphine and Fentanyl in Rats
J Pharmacol Exp Ther 2006 319: 682-692. Published online July 19, 2006; 10.1124/jpet.106.107953 [Abstract] [Full Text] [PDF]  

Lige Liu, Thomas Zheng, Margaret J. Morris, Charlott Wallengren, Alison L. Clarke, Christopher A. Reid, Steven Petrou, and Terence J. O'Brien
The Mechanism of Carbamazepine Aggravation of Absence Seizures
J Pharmacol Exp Ther 2006 319: 790-798. Published online August 8, 2006; 10.1124/jpet.106.104968 [Abstract] [Full Text] [PDF]  

Jan Rodriguez Parkitna, Ilona Obara, Agnieszka Wawrzczak-Bargiela, Wioletta Makuch, Barbara Przewlocka, and Ryszard Przewlocki
Effects of Glycogen Synthase Kinase 3beta and Cyclin-Dependent Kinase 5 Inhibitors on Morphine-Induced Analgesia and Tolerance in Rats
J Pharmacol Exp Ther 2006 319: 832-839. Published online August 10, 2006; 10.1124/jpet.106.107581 [Abstract] [Full Text] [PDF]  

Jue Wang, Samir Haj-Dahmane, and Roh-Yu Shen
Effects of Prenatal Ethanol Exposure on the Excitability of Ventral Tegmental Area Dopamine Neurons in Vitro
J Pharmacol Exp Ther 2006 319: 857-863. Published online August 11, 2006; 10.1124/jpet.106.109041 [Abstract] [Full Text] [PDF]  

Mark A. Simmons
Functional Selectivity of NK1 Receptor Signaling: Peptide Agonists Can Preferentially Produce Receptor Activation or Desensitization
J Pharmacol Exp Ther 2006 319: 907-913. Published online August 17, 2006; 10.1124/jpet.106.109512 [Abstract] [Full Text] [PDF]  

Thomas A. Lanz, Michael J. Karmilowicz, Kathleen M. Wood, Nikolay Pozdnyakov, Ping Du, Mary A. Piotrowski, Tracy M. Brown, Charles E. Nolan, Karl E. G. Richter, James E. Finley, Qing Fei, Charles F. Ebbinghaus, Yuhpyng L. Chen, Douglas K. Spracklin, Barbara Tate, Kieran F. Geoghegan, Lit-Fui Lau, David D. Auperin, and Joel B. Schachter
Concentration-Dependent Modulation of Amyloid-beta in Vivo and in Vitro Using the {gamma}-Secretase Inhibitor, LY-450139
J Pharmacol Exp Ther 2006 319: 924-933. Published online August 18, 2006; 10.1124/jpet.106.110700 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:Back

Jin Yan and Barbara F. Hales
Depletion of Glutathione Induces 4-Hydroxynonenal Protein Adducts and Hydroxyurea Teratogenicity in the Organogenesis Stage Mouse Embryo
J Pharmacol Exp Ther 2006 319: 613-621. Published online August 10, 2006; 10.1124/jpet.106.109850 [Abstract] [Full Text] [PDF]  

Paul S. Fitzmaurice, Junchao Tong, Mehrdad Yazdanpanah, Peter P. Liu, Kathryn S. Kalasinsky, and Stephen J. Kish
Levels of 4-Hydroxynonenal and Malondialdehyde Are Increased in Brain of Human Chronic Users of Methamphetamine
J Pharmacol Exp Ther 2006 319: 703-709. Published online July 20, 2006; 10.1124/jpet.106.109173 [Abstract] [Full Text] [PDF]  

Kevyn E. Merten, Youchun Jiang, Wenke Feng, and Y. James Kang
Calcineurin Activation Is Not Necessary for Doxorubicin-Induced Hypertrophy in H9c2 Embryonic Rat Cardiac Cells: Involvement of the Phosphoinositide 3-Kinase-Akt Pathway
J Pharmacol Exp Ther 2006 319: 934-940. Published online August 22, 2006; 10.1124/jpet.106.108845 [Abstract] [Full Text] [PDF]  

Christy C. Bridges and Rudolfs K. Zalups
System B0,+ and the Transport of Thiol-S-Conjugates of Methylmercury
J Pharmacol Exp Ther 2006 319: 948-956. Published online August 22, 2006; 10.1124/jpet.106.109371 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:Back

About the cover: Double-stained skeletons of the fetuses exposed to HU without or with BSO. See the article by Yan and Hales on page 613 of this issue.



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