PERSPECTIVES IN PHARMACOLOGY:

Ronald J. Tallarida

An Overview of Drug Combination Analysis with Isobolograms
J Pharmacol Exp Ther 2006 319: 1-7. Published online May 2, 2006; 10.1124/jpet.106.104117 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Xia Li, Anne B. Need, Melvyn Baez, and Jeffrey M. Witkin

Metabotropic Glutamate 5 Receptor Antagonism Is Associated with Antidepressant-Like Effects in Mice
J Pharmacol Exp Ther 2006 319: 254-259. Published online June 27, 2006; 10.1124/jpet.106.103143 [Abstract] [Full Text] [PDF]  

Beth Bennett, Phyllis Carosone-Link, Nancy R. Zahniser, and Thomas E. Johnson

Confirmation and Fine Mapping of Ethanol Sensitivity Quantitative Trait Loci, and Candidate Gene Testing in the LXS Recombinant Inbred Mice
J Pharmacol Exp Ther 2006 319: 299-307. Published online June 27, 2006; 10.1124/jpet.106.103572 [Abstract] [Full Text] [PDF] [Data Supplement]   

CARDIOVASCULAR:

Salvatore Cuzzocrea, Emanuela Mazzon, Rosanna Di Paola, Emanuela Esposito, Heather Macarthur, George M. Matuschak, and Daniela Salvemini

A Role for Nitric Oxide-Mediated Peroxynitrite Formation in a Model of Endotoxin-Induced Shock
J Pharmacol Exp Ther 2006 319: 73-81. Published online June 30, 2006; 10.1124/jpet.106.108100 [Abstract] [Full Text] [PDF]  

Philippe de Medina, Nadia Boubekeur, Patrick Balaguer, Gilles Favre, Sandrine Silvente-Poirot, and Marc Poirot

The Prototypical Inhibitor of Cholesterol Esterification, Sah 58-035 [3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide], Is an Agonist of Estrogen Receptors
J Pharmacol Exp Ther 2006 319: 139-149. Published online July 11, 2006; 10.1124/jpet.106.104349 [Abstract] [Full Text] [PDF]  

S. M. Gardiner, J. E. March, P. A. Kemp, S. A. Ballard, and T. Bennett

Regional Hemodynamic Effects of Neutral Endopeptidase Inhibition and Angiotensin (AT₁) Receptor Antagonism Alone or in Combination in Conscious Spontaneously Hypertensive Rats
J Pharmacol Exp Ther 2006 319: 340-348. Published online July 6, 2006; 10.1124/jpet.106.106781 [Abstract] [Full Text] [PDF]  

Huda E. Tawfik, Azza B. El-Remessy, Suraporn Matragoon, Guochuan Ma, Ruth B. Caldwell, and R. William Caldwell

Simvastatin Improves Diabetes-Induced Coronary Endothelial Dysfunction
J Pharmacol Exp Ther 2006 319: 386-395. Published online July 18, 2006; 10.1124/jpet.106.106823 [Abstract] [Full Text] [PDF]  

Miguel Faria, Teresa Magalhães-Cardoso, José-Maria Lafuente-de-Carvalho, and Paulo Correia-de-Sá

Corpus Cavernosum from Men with Vasculogenic Impotence Is Partially Resistant to Adenosine Relaxation due to Endothelial A_2B Receptor Dysfunction
J Pharmacol Exp Ther 2006 319: 405-413. Published online July 12, 2006; 10.1124/jpet.106.107821 [Abstract] [Full Text] [PDF]  

David J. Baker, D. Constantin-Teodosiu, Simon W. Jones, James A. Timmons, and Paul L. Greenhaff

Chronic Treatment with the ₂-Adrenoceptor Agonist Prodrug BRL-47672 Impairs Rat Skeletal Muscle Function by Inducing a Comprehensive Shift to a Faster Muscle Phenotype
J Pharmacol Exp Ther 2006 319: 439-446. Published online July 14, 2006; 10.1124/jpet.106.107045 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Kelly A. Berg, Sylvia Navailles, Teresa A. Sanchez, Yamille M. Silva, Martyn D. Wood, Umberto Spampinato, and William P. Clarke

Differential Effects of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-Hydroxytryptamine_2C Receptor-Mediated Responses
J Pharmacol Exp Ther 2006 319: 260-268. Published online June 28, 2006; 10.1124/jpet.106.104448 [Abstract] [Full Text] [PDF]  

Sabrina Noel, Christelle Faveau, Caroline Norez, Christian Rogier, Yvette Mettey, and Frédéric Becq

Discovery of Pyrrolo[2,3-b]pyrazines Derivatives as Submicromolar Affinity Activators of Wild Type, G551D, and F508del Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels
J Pharmacol Exp Ther 2006 319: 349-359. Published online July 7, 2006; 10.1124/jpet.106.104521 [Abstract] [Full Text] [PDF]  

Piyush M. Vyas, Sanjoy Roychowdhury, Farah D. Khan, Thomas E. Prisinzano, Jatinder Lamba, Erin G. Schuetz, Joyce Blaisdell, Joyce A. Goldstein, Kimber L. Munson, Ronald N. Hines, and Craig K. Svensson

Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: I. Expression and Role of Cytochromes P450
J Pharmacol Exp Ther 2006 319: 488-496. Published online July 20, 2006; 10.1124/jpet.106.105858 [Abstract] [Full Text] [PDF]  

Piyush M. Vyas, Sanjoy Roychowdhury, Sevasti B. Koukouritaki, Ronald N. Hines, Sharon K. Krueger, David E. Williams, William M. Nauseef, and Craig K. Svensson

Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: II. Expression and Role of Flavin-Containing Monooxygenases and Peroxidases
J Pharmacol Exp Ther 2006 319: 497-505. Published online July 20, 2006; 10.1124/jpet.106.105874 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Robert T. Kinobe, Ryan A. Dercho, Jason Z. Vlahakis, James F. Brien, Walter A. Szarek, and Kanji Nakatsu

Inhibition of the Enzymatic Activity of Heme Oxygenases by Azole-Based Antifungal Drugs
J Pharmacol Exp Ther 2006 319: 277-284. Published online June 28, 2006; 10.1124/jpet.106.102699 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Wei Zhou, Xiao-Li Wang, Kathryn G. Lamping, and Hon-Chi Lee

Inhibition of Protein Kinase C Protects against Diabetes-Induced Impairment in Arachidonic Acid Dilation of Small Coronary Arteries
J Pharmacol Exp Ther 2006 319: 199-207. Published online July 21, 2006; 10.1124/jpet.106.106666 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Jai Prakash, Maria Sandovici, Vinay Saluja, Marie Lacombe, Roel Q. J. Schaapveld, Martin H. de Borst, Harry van Goor, Robert H. Henning, Johannes H. Proost, Frits Moolenaar, György Këri, Dirk K. F. Meijer, Klaas Poelstra, and Robbert J. Kok

Intracellular Delivery of the p38 Mitogen-Activated Protein Kinase Inhibitor SB202190 [4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in Renal Tubular Cells: A Novel Strategy to Treat Renal Fibrosis
J Pharmacol Exp Ther 2006 319: 8-19. Published online June 28, 2006; 10.1124/jpet.106.106054 [Abstract] [Full Text] [PDF]  

Iain R. Tough, Nicholas D. Holliday, and Helen M. Cox

Y₄ Receptors Mediate the Inhibitory Responses of Pancreatic Polypeptide in Human and Mouse Colon Mucosa
J Pharmacol Exp Ther 2006 319: 20-30. Published online June 28, 2006; 10.1124/jpet.106.106500 [Abstract] [Full Text] [PDF] [Data Supplement]   

Cathérine Gebhard, Fotios Petroktistis, Hua Zhang, Daniel Kammerer, Christoph Köhle, Karin Klingel, Margitta Albinus, Christoph H. Gleiter, Hartmut Osswald, and Almut Grenz

Role of Renal Nerves and Salt Intake on Erythropoietin Secretion in Rats following Carbon Monoxide Exposure
J Pharmacol Exp Ther 2006 319: 111-116. Published online June 30, 2006; 10.1124/jpet.106.105973 [Abstract] [Full Text] [PDF]  

Ling Cheng, Weibiao Cao, Jose Behar, Claudio Fiocchi, Piero Biancani, and Karen M. Harnett

Acid-Induced Release of Platelet-Activating Factor by Human Esophageal Mucosa Induces Inflammatory Mediators in Circular Smooth Muscle
J Pharmacol Exp Ther 2006 319: 117-126. Published online June 28, 2006; 10.1124/jpet.106.106104 [Abstract] [Full Text] [PDF]  

Noriko Yamabe, Takako Yokozawa, Takeshi Oya, and Mujo Kim

Therapeutic Potential of (-)-Epigallocatechin 3-O-Gallate on Renal Damage in Diabetic Nephropathy Model Rats
J Pharmacol Exp Ther 2006 319: 228-236. Published online July 11, 2006; 10.1124/jpet.106.107029 [Abstract] [Full Text] [PDF]  

Eleonora Distrutti, Luca Sediari, Andrea Mencarelli, Barbara Renga, Stefano Orlandi, Giuseppe Russo, Giuseppe Caliendo, Vincenzo Santagada, Giuseppe Cirino, John L. Wallace, and Stefano Fiorucci

5-Amino-2-hydroxybenzoic Acid 4-(5-Thioxo-5H-[1,2]dithiol-3yl)-phenyl Ester (ATB-429), a Hydrogen Sulfide-Releasing Derivative of Mesalamine, Exerts Antinociceptive Effects in a Model of Postinflammatory Hypersensitivity
J Pharmacol Exp Ther 2006 319: 447-458. Published online July 19, 2006; 10.1124/jpet.106.106435 [Abstract] [Full Text] [PDF] [Data Supplement]   

Tomasz Brzozowski, Peter C. Konturek, Zbigniew Sliwowski, Robert Pajdo, Danuta Drozdowicz, Slawomir Kwiecien, Grzegorz Burnat, Stanislaw J. Konturek, and Wieslaw W. Pawlik

Prostaglandin/Cyclooxygenase Pathway in Ghrelin-Induced Gastroprotection against Ischemia-Reperfusion Injury
J Pharmacol Exp Ther 2006 319: 477-487. Published online July 25, 2006; 10.1124/jpet.106.105932 [Abstract] [Full Text] [PDF]  

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA:

Li Qian, Michelle L. Block, Sung-Jen Wei, Chiou-feng Lin, Jeffrey Reece, Hao Pang, Belinda Wilson, Jau-Shyong Hong, and Patrick M. Flood

Interleukin-10 Protects Lipopolysaccharide-Induced Neurotoxicity in Primary Midbrain Cultures by Inhibiting the Function of NADPH Oxidase
J Pharmacol Exp Ther 2006 319: 44-52. Published online June 28, 2006; 10.1124/jpet.106.106351 [Abstract] [Full Text] [PDF]  

C. S. Moore, N. Earl, R. Frenette, A. Styhler, J. A. Mancini, D. W. Nicholson, A. L. O. Hebb, T. Owens, and G. S. Robertson

Peripheral Phosphodiesterase 4 Inhibition Produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) Prevents Experimental Autoimmune Encephalomyelitis
J Pharmacol Exp Ther 2006 319: 63-72. Published online June 29, 2006; 10.1124/jpet.106.106096 [Abstract] [Full Text] [PDF]  

Maya Margalit, Zvi Shalev, Orit Pappo, Miriam Sklair-Levy, Ruslana Alper, Moshe Gomori, Dean Engelhardt, Elazar Rabbani, and Yaron Ilan

Glucocerebroside Ameliorates the Metabolic Syndrome in OB/OB Mice
J Pharmacol Exp Ther 2006 319: 105-110. Published online June 30, 2006; 10.1124/jpet.106.104950 [Abstract] [Full Text] [PDF]  

Salvatore Cuzzocrea, Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Wookee Min, Rosanna Di Paola, Carmelo Muià, Jia-He Li, Emanuela Esposito, Placido Bramanti, Weizheng Xu, Edmond Massuda, Jie Zhang, and Zhao-Qi Wang

Poly(ADP-Ribose) Glycohydrolase Activity Mediates Post-Traumatic Inflammatory Reaction after Experimental Spinal Cord Trauma
J Pharmacol Exp Ther 2006 319: 127-138. Published online July 6, 2006; 10.1124/jpet.106.108076 [Abstract] [Full Text] [PDF]  

Tangying Lu, Cathy Newton, Izabella Perkins, Herman Friedman, and Thomas W. Klein

Cannabinoid Treatment Suppresses the T-Helper Cell-Polarizing Function of Mouse Dendritic Cells Stimulated with Legionella pneumophila Infection
J Pharmacol Exp Ther 2006 319: 269-276. Published online July 12, 2006; 10.1124/jpet.106.108381 [Abstract] [Full Text] [PDF]  

Carmen Navarrete, Rocío Sancho, Francisco J. Caballero, Federica Pollastro, Bernd L. Fiebich, Olov Sterner, Giovanni Appendino, and Eduardo Muñoz

Basiliolides, a Class of Tetracyclic C19 Dilactones from Thapsia garganica, Release Ca²⁺ from the Endoplasmic Reticulum and Regulate the Activity of the Transcription Factors Nuclear Factor of Activated T Cells, Nuclear Factor-B, and Activator Protein 1 in T Lymphocytes
J Pharmacol Exp Ther 2006 319: 422-430. Published online July 13, 2006; 10.1124/jpet.106.108209 [Abstract] [Full Text] [PDF]  

Kerryn McCluskie, Uwe Klein, Chris Linnevers, Yu-hua Ji, Alfred Yang, Craig Husfeld, and G. Roger Thomas

Phosphodiesterase Type 4 Inhibitors Cause Proinflammatory Effects in Vivo
J Pharmacol Exp Ther 2006 319: 468-476. Published online July 21, 2006; 10.1124/jpet.106.105080 [Abstract] [Full Text] [PDF]  

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:

Frantisek Staud, Zuzana Vackova, Katerina Pospechova, Petr Pavek, Martina Ceckova, Antonin Libra, Lenka Cygalova, Petr Nachtigal, and Zdenek Fendrich

Expression and Transport Activity of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Dually Perfused Rat Placenta and HRP-1 Cell Line
J Pharmacol Exp Ther 2006 319: 53-62. Published online June 29, 2006; 10.1124/jpet.106.105023 [Abstract] [Full Text] [PDF]  

Xiao-Xia Yang, Ze-Ping Hu, An-Long Xu, Wei Duan, Yi-Zhun Zhu, Min Huang, Fwu-Shan Sheu, Qiang Zhang, Jin-Song Bian, Eli Chan, Xiaotian Li, Jian-Cheng Wang, and Shu-Feng Zhou

A Mechanistic Study on Reduced Toxicity of Irinotecan by Coadministered Thalidomide, a Tumor Necrosis Factor- Inhibitor
J Pharmacol Exp Ther 2006 319: 82-104. Published online June 30, 2006; 10.1124/jpet.106.103606 [Abstract] [Full Text] [PDF]  

Ken Ogasawara, Tomohiro Terada, Jun-ichi Asaka, Toshiya Katsura, and Ken-ichi Inui

Human Organic Anion Transporter 3 Gene Is Regulated Constitutively and Inducibly via a cAMP-Response Element
J Pharmacol Exp Ther 2006 319: 317-322. Published online June 29, 2006; 10.1124/jpet.106.108233 [Abstract] [Full Text] [PDF]  

Maxwell Afari Gyamfi, Michael George Kocsis, Lin He, Guoli Dai, Alphonse John Mendy, and Yu-Jui Yvonne Wan

The Role of Retinoid X Receptor in Regulating Alcohol Metabolism
J Pharmacol Exp Ther 2006 319: 360-368. Published online July 7, 2006; 10.1124/jpet.106.108175 [Abstract] [Full Text] [PDF]  

Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Joan E. Humphreys, Xianbin Tian, Ken-ichi Nezasa, and Kim L. R. Brouwer

Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat
J Pharmacol Exp Ther 2006 319: 459-467. Published online July 20, 2006; 10.1124/jpet.106.101840 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Manuel Rodriguez, Ingrid Morales, Isabel Gomez, Sergio Gonzalez, Tomas Gonzalez-Hernandez, and Jose Luis Gonzalez-Mora

Heterogeneous Dopamine Neurochemistry in the Striatum: The Fountain-Drain Matrix
J Pharmacol Exp Ther 2006 319: 31-43. Published online July 6, 2006; 10.1124/jpet.106.104687 [Abstract] [Full Text] [PDF]  

Sun Hee Kim, Seok Joon Won, Xiao Ou Mao, Catherine Ledent, Kunlin Jin, and David A. Greenberg

Role for Neuronal Nitric-Oxide Synthase in Cannabinoid-Induced Neurogenesis
J Pharmacol Exp Ther 2006 319: 150-154. Published online July 10, 2006; 10.1124/jpet.106.107698 [Abstract] [Full Text] [PDF]  

Jie Wu, Jun Hu, Yu-Ping Chen, Teruko Takeo, Sechiko Suga, Jamie DeChon, Qiang Liu, Ke-Chun Yang, Paul A. St. John, Gang Hu, Hai Wang, and Makoto Wakui

Iptakalim Modulates ATP-Sensitive K⁺ Channels in Dopamine Neurons from Rat Substantia Nigra Pars Compacta
J Pharmacol Exp Ther 2006 319: 155-164. Published online July 12, 2006; 10.1124/jpet.106.106286 [Abstract] [Full Text] [PDF]  

Dong-Mei Chen, Liang Xiao, Xin Cai, Rong Zeng, and Xing-Zu Zhu

Involvement of Multitargets in Paeoniflorin-Induced Preconditioning
J Pharmacol Exp Ther 2006 319: 165-180. Published online July 13, 2006; 10.1124/jpet.106.104380 [Abstract] [Full Text] [PDF]  

Frank Henle, Jost Leemhuis, Catharina Fischer, Hans H. Bock, Kerstin Lindemeyer, Thomas J. Feuerstein, and Dieter K. Meyer

Gabapentin-Lactam Induces Dendritic Filopodia and Motility in Cultured Hippocampal Neurons
J Pharmacol Exp Ther 2006 319: 181-191. Published online July 14, 2006; 10.1124/jpet.106.106146 [Abstract] [Full Text] [PDF]  

Lana Klionsky, Rami Tamir, Bob Holzinger, Xiaojuan Bi, Jane Talvenheimo, Helen Kim, Frank Martin, Jean-Claude Louis, James J. S. Treanor, and Narender R. Gavva

A Polyclonal Antibody to the Prepore Loop of Transient Receptor Potential Vanilloid Type 1 Blocks Channel Activation
J Pharmacol Exp Ther 2006 319: 192-198. Published online July 14, 2006; 10.1124/jpet.106.108092 [Abstract] [Full Text] [PDF]  

C. M. Borghese, D. F. Werner, N. Topf, N. V. Baron, L. A. Henderson, S. L. Boehm, II, Y. A. Blednov, A. Saad, S. Dai, R. A. Pearce, R. A. Harris, G. E. Homanics, and N. L. Harrison

An Isoflurane- and Alcohol-Insensitive Mutant GABA_A Receptor ₁ Subunit with Near-Normal Apparent Affinity for GABA: Characterization in Heterologous Systems and Production of Knockin Mice
J Pharmacol Exp Ther 2006 319: 208-218. Published online June 28, 2006; 10.1124/jpet.106.104406 [Abstract] [Full Text] [PDF]  

David F. Werner, Yuri A. Blednov, Olusegun J. Ariwodola, Yuval Silberman, Exazevia Logan, Raymond B. Berry, Cecilia M. Borghese, Douglas B. Matthews, Jeffrey L. Weiner, Neil L. Harrison, R. Adron Harris, and Gregg E. Homanics

Knockin Mice with Ethanol-Insensitive 1-Containing -Aminobutyric Acid Type A Receptors Display Selective Alterations in Behavioral Responses to Ethanol
J Pharmacol Exp Ther 2006 319: 219-227. Published online June 19, 2006; 10.1124/jpet.106.106161 [Abstract] [Full Text] [PDF]  

John S. Partilla, Allison G. Dempsey, Ameet S. Nagpal, Bruce E. Blough, Michael H. Baumann, and Richard B. Rothman

Interaction of Amphetamines and Related Compounds at the Vesicular Monoamine Transporter
J Pharmacol Exp Ther 2006 319: 237-246. Published online July 11, 2006; 10.1124/jpet.106.103622 [Abstract] [Full Text] [PDF]  

Loriann Mahurter, Carrie Garceau, Jacqueline Marino, Helmut Schmidhammer, Géza Tóth, and Gavril W. Pasternak

Separation of Binding Affinity and Intrinsic Activity of the Potent µ-Opioid 14-Methoxymetopon
J Pharmacol Exp Ther 2006 319: 247-253. Published online June 26, 2006; 10.1124/jpet.106.105395 [Abstract] [Full Text] [PDF]  

Tanuja Bordia, Neeraja Parameswaran, Hong Fan, J. William Langston, J. Michael McIntosh, and Maryka Quik

Partial Recovery of Striatal Nicotinic Receptors in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Lesioned Monkeys with Chronic Oral Nicotine
J Pharmacol Exp Ther 2006 319: 285-292. Published online July 12, 2006; 10.1124/jpet.106.106997 [Abstract] [Full Text] [PDF]  

John W. Ryder, Julie F. Falcone, Jason R. Manro, Kjell A. Svensson, and Kalpana M. Merchant

Pharmacological Characterization of cGMP Regulation by the Biarylpropylsulfonamide Class of Positive, Allosteric Modulators of -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors
J Pharmacol Exp Ther 2006 319: 293-298. Published online June 27, 2006; 10.1124/jpet.106.105734 [Abstract] [Full Text] [PDF]  

Hong-Mei Liu, Xue-Feng Liu, Jin-Long Yao, Chang-Lin Wang, Ye Yu, and Rui Wang

Utilization of Combined Chemical Modifications to Enhance the Blood-Brain Barrier Permeability and Pharmacological Activity of Endomorphin-1
J Pharmacol Exp Ther 2006 319: 308-316. Published online June 27, 2006; 10.1124/jpet.106.106484 [Abstract] [Full Text] [PDF]  

Hye Sook Ahn, Sung Eun Kim, Hyun-Jong Jang, Myung-Jun Kim, Duck-Joo Rhie, Shin-Hee Yoon, Yang-Hyeok Jo, Myung-Suk Kim, Ki-Wug Sung, and Sang June Hahn

Interaction of Riluzole with the Closed Inactivated State of Kv4.3 Channels
J Pharmacol Exp Ther 2006 319: 323-331. Published online June 30, 2006; 10.1124/jpet.106.106724 [Abstract] [Full Text] [PDF]  

Michael Rotstein, Haim Bassan, Naam Kariv, Zipora Speiser, Shaul Harel, and Illana Gozes

NAP Enhances Neurodevelopment of Newborn Apolipoprotein E-Deficient Mice Subjected to Hypoxia
J Pharmacol Exp Ther 2006 319: 332-339. Published online July 5, 2006; 10.1124/jpet.106.106898 [Abstract] [Full Text] [PDF] [Erratum]   

Hélio R. Santos, Helizane S. Ribeiro, Pedro Setti-Perdigão, Edson X. Albuquerque, and Newton G. Castro

The Magnitude of 7 Nicotinic Receptor Currents in Rat Hippocampal Neurons Is Dependent upon GABAergic Activity and Depolarization
J Pharmacol Exp Ther 2006 319: 376-385. Published online July 12, 2006; 10.1124/jpet.106.106385 [Abstract] [Full Text] [PDF]  

Carrie K. Jones, Andrew Alt, Ann Marie Ogden, David Bleakman, Rosa M. A. Simmons, Smriti Iyengar, Esteban Dominguez, Paul L. Ornstein, and Harlan E. Shannon

Antiallodynic and Antihyperalgesic Effects of Selective Competitive GLU_K5 (GluR5) Ionotropic Glutamate Receptor Antagonists in the Capsaicin and Carrageenan Models in Rats
J Pharmacol Exp Ther 2006 319: 396-404. Published online July 12, 2006; 10.1124/jpet.106.105601 [Abstract] [Full Text] [PDF]  

Kristen A. Horner, Scot C. Westwood, Glen R. Hanson, and Kristen A. Keefe

Multiple High Doses of Methamphetamine Increase the Number of Preproneuropeptide Y mRNA-Expressing Neurons in the Striatum of Rat via a Dopamine D1 Receptor-Dependent Mechanism
J Pharmacol Exp Ther 2006 319: 414-421. Published online July 13, 2006; 10.1124/jpet.106.106856 [Abstract] [Full Text] [PDF]  

Megumi Yamashita, William Marszalec, Jay Z. Yeh, and Toshio Narahashi

Effects of Ethanol on Tonic GABA Currents in Cerebellar Granule Cells and Mammalian Cells Recombinantly Expressing GABA_A Receptors
J Pharmacol Exp Ther 2006 319: 431-438. Published online July 14, 2006; 10.1124/jpet.106.106260 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Jason M. Walraven, Mark A. Doll, and David W. Hein

Identification and Characterization of Functional Rat Arylamine N-Acetyltransferase 3: Comparisons with Rat Arylamine N-Acetyltransferases 1 and 2
J Pharmacol Exp Ther 2006 319: 369-375. Published online July 7, 2006; 10.1124/jpet.106.108399 [Abstract] [Full Text] [PDF]  

ERRATUM:

Correction to "Mitochondrial Arginase II Modulates Nitric-Oxide Synthesis through Nonfreely Exchangeable L-Arginine Pools in Human Endothelial Cells"
J Pharmacol Exp Ther 2006 319: 506. [Full Text] [PDF]  

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