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September 2006; 318 (3)   [Index by Author]  [Cover Caption]
      Down PERSPECTIVES IN PHARMACOLOGY
      Down BEHAVIORAL PHARMACOLOGY
      Down CARDIOVASCULAR
      Down CELLULAR AND MOLECULAR
      Down CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
      Down ENDOCRINE AND DIABETES
      Down GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
      Down INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA
      Down METABOLISM, TRANSPORT, AND PHARMACOGENOMICS
      Down NEUROPHARMACOLOGY
      Down TOXICOLOGY
      Down ERRATUM
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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |
To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

PERSPECTIVES IN PHARMACOLOGY:Back

Carlos Medina and Marek W. Radomski
Role of Matrix Metalloproteinases in Intestinal Inflammation
J Pharmacol Exp Ther 2006 318: 933-938. Published online April 27, 2006; 10.1124/jpet.106.103465 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:Back

N. Bonnet, N. Laroche, L. Vico, E. Dolleans, C. L. Benhamou, and D. Courteix
Dose Effects of Propranolol on Cancellous and Cortical Bone in Ovariectomized Adult Rats
J Pharmacol Exp Ther 2006 318: 1118-1127. Published online June 1, 2006; 10.1124/jpet.106.105437 [Abstract] [Full Text] [PDF]  

Tomasz Kos, Beata Legutko, Wojciech Danysz, Gary Samoriski, and Piotr Popik
Enhancement of Antidepressant-Like Effects but Not Brain-Derived Neurotrophic Factor mRNA Expression by the Novel N-Methyl-D-aspartate Receptor Antagonist Neramexane in Mice
J Pharmacol Exp Ther 2006 318: 1128-1136. Published online June 1, 2006; 10.1124/jpet.106.103697 [Abstract] [Full Text] [PDF]  

M. C. Holden Ko, Hui Wei, James H. Woods, and Robert T. Kennedy
Effects of Intrathecally Administered Nociceptin/Orphanin FQ in Monkeys: Behavioral and Mass Spectrometric Studies
J Pharmacol Exp Ther 2006 318: 1257-1264. Published online June 9, 2006; 10.1124/jpet.106.106120 [Abstract] [Full Text] [PDF]  

Bradford D. Fischer and Linda A. Dykstra
Interactions between an N-Methyl-D-aspartate Antagonist and Low-Efficacy Opioid Receptor Agonists in Assays of Schedule-Controlled Responding and Thermal Nociception
J Pharmacol Exp Ther 2006 318: 1300-1306. Published online June 13, 2006; 10.1124/jpet.106.101683 [Abstract] [Full Text] [PDF]  

Sylvia Fitting, Rosemarie M. Booze, and Charles F. Mactutus
Neonatal Intrahippocampal Glycoprotein 120 Injection: The Role of Dopaminergic Alterations in Prepulse Inhibition in Adult Rats
J Pharmacol Exp Ther 2006 318: 1352-1358. Published online June 19, 2006; 10.1124/jpet.106.105742 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:Back

Francis G. Spinale, G. Patricia Escobar, Jennifer W. Hendrick, Leslie L. Clark, Sarah S. Camens, Joseph P. Mingoia, Christina G. Squires, Robert E. Stroud, and John S. Ikonomidis
Chronic Matrix Metalloproteinase Inhibition Following Myocardial Infarction in Mice: Differential Effects on Short and Long-Term Survival
J Pharmacol Exp Ther 2006 318: 966-973. Published online June 6, 2006; 10.1124/jpet.106.104455 [Abstract] [Full Text] [PDF]  

Gabriella Pridjian, Candice Pridjian, Svitlana Danchuk, Monica Ianosi-Irimie, Hop V. Vu, and Jules B. Puschett
Beneficial Effects of Metolazone in a Rat Model of Preeclampsia
J Pharmacol Exp Ther 2006 318: 1027-1032. Published online May 22, 2006; 10.1124/jpet.106.104901 [Abstract] [Full Text] [PDF]  

Jian Yang, Ruirui Ji, Yunhui Cheng, Ju-Zhong Sun, Lisa K. Jennings, and Chunxiang Zhang
L-Arginine Chlorination Results in the Formation of a Nonselective Nitric-Oxide Synthase Inhibitor
J Pharmacol Exp Ther 2006 318: 1044-1049. Published online May 22, 2006; 10.1124/jpet.106.104422 [Abstract] [Full Text] [PDF]  

Yanbin Ji and Brian M. Bennett
Biotransformation of Glyceryl Trinitrate by Rat Hepatic Microsomal Glutathione S-Transferase 1
J Pharmacol Exp Ther 2006 318: 1050-1056. Published online May 23, 2006; 10.1124/jpet.106.103713 [Abstract] [Full Text] [PDF]  

Hideaki Endo, Masahito Miura, Masanori Hirose, Jun Takahashi, Makoto Nakano, Yuji Wakayama, Yoshinao Sugai, Yutaka Kagaya, Jun Watanabe, Kunio Shirato, and Hiroaki Shimokawa
Reduced Inotropic Effect of Nifekalant in Failing Hearts in Rats
J Pharmacol Exp Ther 2006 318: 1102-1107. Published online May 31, 2006; 10.1124/jpet.106.102780 [Abstract] [Full Text] [PDF]  

Tien Thuy Nguyen, Nga Cao, Jennifer Lynn Short, and Paul James White
Intravenous Insulin-like Growth Factor-I Receptor Antisense Treatment Reduces Angiotensin Receptor Expression and Function in Spontaneously Hypertensive Rats
J Pharmacol Exp Ther 2006 318: 1171-1177. Published online June 2, 2006; 10.1124/jpet.106.103655 [Abstract] [Full Text] [PDF]  

Laine J. Murphey, Hector A. Malave, Jeff Petro, Italo Biaggioni, Daniel W. Byrne, Douglas E. Vaughan, James M. Luther, Mias Pretorius, and Nancy J. Brown
Bradykinin and Its Metabolite Bradykinin 1-5 Inhibit Thrombin-Induced Platelet Aggregation in Humans
J Pharmacol Exp Ther 2006 318: 1287-1292. Published online June 13, 2006; 10.1124/jpet.106.104026 [Abstract] [Full Text] [PDF]  

Jeffrey J. Olearczyk, Mary B. Field, In-Hae Kim, Christophe Morisseau, Bruce D. Hammock, and John D. Imig
Substituted Adamantyl-Urea Inhibitors of the Soluble Epoxide Hydrolase Dilate Mesenteric Resistance Vessels
J Pharmacol Exp Ther 2006 318: 1307-1314. Published online June 13, 2006; 10.1124/jpet.106.103556 [Abstract] [Full Text] [PDF]  

Matlubur Rahman, Akira Nishiyama, Peng Guo, Yukiko Nagai, Guo-Xing Zhang, Yoshihide Fujisawa, Yu-Yan Fan, Shoji Kimura, Naohisa Hosomi, Koji Omori, Youichi Abe, and Masakazu Kohno
Effects of Adrenomedullin on Cardiac Oxidative Stress and Collagen Accumulation in Aldosterone-Dependent Malignant Hypertensive Rats
J Pharmacol Exp Ther 2006 318: 1323-1329. Published online June 14, 2006; 10.1124/jpet.106.105106 [Abstract] [Full Text] [PDF]  

Gökce Topal, Annie Brunet, Laurence Walch, Jean-Luc Boucher, and Monique David-Dufilho
Mitochondrial Arginase II Modulates Nitric-Oxide Synthesis through Nonfreely Exchangeable L-Arginine Pools in Human Endothelial Cells
J Pharmacol Exp Ther 2006 318: 1368-1374. Published online June 26, 2006; 10.1124/jpet.106.103747 [Abstract] [Full Text] [PDF] [Erratum]   

CELLULAR AND MOLECULAR:Back

Steven C. Prinster, Tomas G. Holmqvist, and Randy A. Hall
{alpha}2C-Adrenergic Receptors Exhibit Enhanced Surface Expression and Signaling upon Association with beta2-Adrenergic Receptors
J Pharmacol Exp Ther 2006 318: 974-981. Published online June 6, 2006; 10.1124/jpet.106.106526 [Abstract] [Full Text] [PDF]  

Yurii V. Mukhin, Monika Gooz, John R. Raymond, and Maria N. Garnovskaya
Collagenase-2 and -3 Mediate Epidermal Growth Factor Receptor Transactivation by Bradykinin B2 Receptor in Kidney Cells
J Pharmacol Exp Ther 2006 318: 1033-1043. Published online May 22, 2006; 10.1124/jpet.106.104000 [Abstract] [Full Text] [PDF]  

Mamatha Garige, Maokai Gong, and M. Raj Lakshman
Ethanol Destabilizes Liver Galbetal, 4GlcNAc {alpha}2,6-Sialyltransferase, mRNA by Depleting a 3'-Untranslated Region-Specific Binding Protein
J Pharmacol Exp Ther 2006 318: 1076-1082. Published online May 23, 2006; 10.1124/jpet.106.103861 [Abstract] [Full Text] [PDF]  

Terry W. Moody, Li-Chun Sun, Samuel A. Mantey, Tapas Pradhan, L. Vienna Mackey, Nieves Gonzales, Joseph A. Fuselier, David H. Coy, and Robert T. Jensen
In Vitro and in Vivo Antitumor Effects of Cytotoxic Camptothecin-Bombesin Conjugates Are Mediated by Specific Interaction with Cellular Bombesin Receptors
J Pharmacol Exp Ther 2006 318: 1265-1272. Published online June 9, 2006; 10.1124/jpet.106.104141 [Abstract] [Full Text] [PDF]  

Shuxian Hu, Maxim C.-J. Cheeran, Wen S. Sheng, Hsiao T. Ni, James R. Lokensgard, and Phillip K. Peterson
Cocaine Alters Proliferation, Migration, and Differentiation of Human Fetal Brain-Derived Neural Precursor Cells
J Pharmacol Exp Ther 2006 318: 1280-1286. Published online June 9, 2006; 10.1124/jpet.106.103853 [Abstract] [Full Text] [PDF]  

Aude Lafoux, Alexandra Divet, Pascal Gervier, and Corinne Huchet-Cadiou
Greater Susceptibility of the Sarcoplasmic Reticulum to H2O2 Injuries in Diaphragm Muscle from mdx Mice
J Pharmacol Exp Ther 2006 318: 1359-1367. Published online June 26, 2006; 10.1124/jpet.106.103291 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:Back

Giovanna Petrangolini, Rosanna Supino, Graziella Pratesi, Laura Dal Bo, Monica Tortoreto, Anna Cleta Croce, Paola Misiano, Pietro Belfiore, Carlo Farina, and Franco Zunino
Effect of a Novel Vacuolar-H+-ATPase Inhibitor on Cell and Tumor Response to Camptothecins
J Pharmacol Exp Ther 2006 318: 939-946. Published online May 19, 2006; 10.1124/jpet.106.103481 [Abstract] [Full Text] [PDF]  

Xavier de Leval, Thibaut Dassesse, Jean-Michel Dogné, David Waltregny, Akeila Bellahcène, Valérie Benoit, Bernard Pirotte, and Vincent Castronovo
Evaluation of Original Dual Thromboxane A2 Modulators as Antiangiogenic Agents
J Pharmacol Exp Ther 2006 318: 1057-1067. Published online May 23, 2006; 10.1124/jpet.106.101188 [Abstract] [Full Text] [PDF]  

Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco, and Vincenzo Di Marzo
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
J Pharmacol Exp Ther 2006 318: 1375-1387. Published online May 25, 2006; 10.1124/jpet.106.105247 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:Back

Takanori Kudo, Jie Wu, Yoshiji Ogawa, Sechiko Suga, Noriyuki Hasegawa, Toshihiro Suda, Hiroki Mizukami, Soroku Yagihashi, and Makoto Wakui
Novel Mechanism of Chronic Exposure of Oleic Acid-Induced Insulin Release Impairment in Rat Pancreatic beta-Cells
J Pharmacol Exp Ther 2006 318: 1203-1210. Published online June 6, 2006; 10.1124/jpet.106.105759 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:Back

Dev K. Singh, Li Li, and Todd D. Porter
Policosanol Inhibits Cholesterol Synthesis in Hepatoma Cells by Activation of AMP-Kinase
J Pharmacol Exp Ther 2006 318: 1020-1026. Published online May 19, 2006; 10.1124/jpet.106.107144 [Abstract] [Full Text] [PDF]  

Carolina I. Ghanem, Paula C. Gómez, María C. Arana, María Perassolo, Griselda Delli Carpini, Marcelo G. Luquita, Luis M. Veggi, Viviana A. Catania, Laura A. Bengochea, and Aldo D. Mottino
Induction of Rat Intestinal P-glycoprotein by Spironolactone and Its Effect on Absorption of Orally Administered Digoxin
J Pharmacol Exp Ther 2006 318: 1146-1152. Published online June 1, 2006; 10.1124/jpet.106.105668 [Abstract] [Full Text] [PDF]  

Jonathan Gass, Harmit Vora, Michael T. Bethune, Gary M. Gray, and Chaitan Khosla
Effect of Barley Endoprotease EP-B2 on Gluten Digestion in the Intact Rat
J Pharmacol Exp Ther 2006 318: 1178-1186. Published online June 6, 2006; 10.1124/jpet.106.104315 [Abstract] [Full Text] [PDF]  

Sylvia Notenboom, Alfons C. Wouterse, Bram Peters, Leon H. Kuik, Suzanne Heemskerk, Frans G. M. Russel, and Rosalinde Masereeuw
Increased Apical Insertion of the Multidrug Resistance Protein 2 (MRP2/ABCC2) in Renal Proximal Tubules following Gentamicin Exposure
J Pharmacol Exp Ther 2006 318: 1194-1202. Published online June 6, 2006; 10.1124/jpet.106.104547 [Abstract] [Full Text] [PDF]  

Geraldine Saavedra, Wenliang Zhang, Brianna Peterson, and B. S. Cummings
Differential Roles for Cytosolic and Microsomal Ca2+-Independent Phospholipase A2 in Cell Growth and Maintenance of Phospholipids
J Pharmacol Exp Ther 2006 318: 1211-1219. Published online June 8, 2006; 10.1124/jpet.106.105650 [Abstract] [Full Text] [PDF]  

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA:Back

Feng-Qiao Li, Gregory D. Sempowski, Suzanne E. McKenna, Daniel T. Laskowitz, Carol A. Colton, and Michael P. Vitek
Apolipoprotein E-Derived Peptides Ameliorate Clinical Disability and Inflammatory Infiltrates into the Spinal Cord in a Murine Model of Multiple Sclerosis
J Pharmacol Exp Ther 2006 318: 956-965. Published online June 1, 2006; 10.1124/jpet.106.103671 [Abstract] [Full Text] [PDF]  

Yi-Na Zhu, Xiang-Gen Zhong, Jia-Quan Feng, Yi-Fu Yang, Yun-Feng Fu, Jia Ni, Qun-Fang Liu, Wei Tang, Wei-Min Zhao, and Jian-Ping Zuo
Periplocoside E Inhibits Experimental Allergic Encephalomyelitis by Suppressing Interleukin 12-Dependent CCR5 Expression and Interferon-{gamma}-Dependent CXCR3 Expression in T Lymphocytes
J Pharmacol Exp Ther 2006 318: 1153-1162. Published online June 2, 2006; 10.1124/jpet.106.105445 [Abstract] [Full Text] [PDF] [Data Supplement]   

Michio Miyoshi, Yoshinori Kitagawa, Toshiaki Imoto, and Tatsuo Watanabe
Effect of Natriuretic Peptide Receptor Antagonist on Lipopolysaccharide-Induced Fever in Rats: Is Natriuretic Peptide an Endogenous Antipyretic?
J Pharmacol Exp Ther 2006 318: 1163-1170. Published online June 2, 2006; 10.1124/jpet.106.102731 [Abstract] [Full Text] [PDF]  

Mohamed G. Bani-Hani, David Greenstein, Brian E. Mann, Colin J. Green, and Roberto Motterlini
Modulation of Thrombin-Induced Neuroinflammation in BV-2 Microglia by Carbon Monoxide-Releasing Molecule 3
J Pharmacol Exp Ther 2006 318: 1315-1322. Published online June 13, 2006; 10.1124/jpet.106.104729 [Abstract] [Full Text] [PDF]  

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:Back

Ute M. Kent, Hsia-lien Lin, Kathleen R. Noon, Danni L. Harris, and Paul F. Hollenberg
Metabolism of Bergamottin by Cytochromes P450 2B6 and 3A5
J Pharmacol Exp Ther 2006 318: 992-1005. Published online June 19, 2006; 10.1124/jpet.105.099887 [Abstract] [Full Text] [PDF] [Data Supplement]   

Mary Peace McRae, Carolina M. Lowe, Xianbin Tian, David L. Bourdet, Richard H. Ho, Brenda F. Leake, Richard B. Kim, Kim L. R. Brouwer, and Angela D. M. Kashuba
Ritonavir, Saquinavir, and Efavirenz, but Not Nevirapine, Inhibit Bile Acid Transport in Human and Rat Hepatocytes
J Pharmacol Exp Ther 2006 318: 1068-1075. Published online May 23, 2006; 10.1124/jpet.106.102657 [Abstract] [Full Text] [PDF]  

Minoru Miyake, Jiangang Shen, Shimin Liu, Honglian Shi, Wenlan Liu, Zhongrui Yuan, Aaron Pritchard, Joseph P. Y. Kao, Ke Jian Liu, and Gerald M. Rosen
Acetoxymethoxycarbonyl Nitroxides as Electron Paramagnetic Resonance Proimaging Agents to Measure O2 Levels in Mouse Brain: A Pharmacokinetic and Pharmacodynamic Study
J Pharmacol Exp Ther 2006 318: 1187-1193. Published online June 6, 2006; 10.1124/jpet.106.106245 [Abstract] [Full Text] [PDF]  

Aleksandra Galetin and J. Brian Houston
Intestinal and Hepatic Metabolic Activity of Five Cytochrome P450 Enzymes: Impact on Prediction of First-Pass Metabolism
J Pharmacol Exp Ther 2006 318: 1220-1229. Published online June 8, 2006; 10.1124/jpet.106.106013 [Abstract] [Full Text] [PDF]  

Stefan Oswald, Sabine Westrup, Markus Grube, Heyo K. Kroemer, Werner Weitschies, and Werner Siegmund
Disposition and Sterol-Lowering Effect of Ezetimibe in Multidrug Resistance-Associated Protein 2-Deficient Rats
J Pharmacol Exp Ther 2006 318: 1293-1299. Published online June 13, 2006; 10.1124/jpet.106.104018 [Abstract] [Full Text] [PDF]  

Chi Chen, Linghua Meng, Xiaochao Ma, Kristopher W. Krausz, Yves Pommier, Jeffrey R. Idle, and Frank J. Gonzalez
Urinary Metabolite Profiling Reveals CYP1A2-Mediated Metabolism of NSC686288 (Aminoflavone)
J Pharmacol Exp Ther 2006 318: 1330-1342. Published online June 14, 2006; 10.1124/jpet.106.105213 [Abstract] [Full Text] [PDF]  

Easwaran Ravichandran, Yujing Gong, Fetweh H. Al Saleem, Denise M. Ancharski, Suresh G. Joshi, and Lance L. Simpson
An Initial Assessment of the Systemic Pharmacokinetics of Botulinum Toxin
J Pharmacol Exp Ther 2006 318: 1343-1351. Published online June 16, 2006; 10.1124/jpet.106.104661 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:Back

Anthony J. Williams, Charisma C. Bautista, Ren-Wu Chen, Jitendra R. Dave, Xi-Chun M. Lu, Frank C. Tortella, and Jed A. Hartings
Evaluation of Gabapentin and Ethosuximide for Treatment of Acute Nonconvulsive Seizures following Ischemic Brain Injury in Rats
J Pharmacol Exp Ther 2006 318: 947-955. Published online May 25, 2006; 10.1124/jpet.106.105999 [Abstract] [Full Text] [PDF]  

Jun Matsumoto, Motohiro Morioka, Yu Hasegawa, Takayuki Kawano, Yutaka Yoshinaga, Tatsumi Maeda, Shigetoshi Yano, Yutaka Kai, Kohji Fukunaga, and Jun-ichi Kuratsu
Sodium Orthovanadate Enhances Proliferation of Progenitor Cells in the Adult Rat Subventricular Zone after Focal Cerebral Ischemia
J Pharmacol Exp Ther 2006 318: 982-991. Published online June 16, 2006; 10.1124/jpet.106.104562 [Abstract] [Full Text] [PDF] [Data Supplement]   

Henrik H. Hansen, Christina Ebbesen, Claus Mathiesen, Pia Weikop, Lars Christian Rønn, Olivier Waroux, Jacqueline Scuvée-Moreau, Vincent Seutin, and Jens D. Mikkelsen
The KCNQ Channel Opener Retigabine Inhibits the Activity of Mesencephalic Dopaminergic Systems of the Rat
J Pharmacol Exp Ther 2006 318: 1006-1019. Published online June 14, 2006; 10.1124/jpet.106.106757 [Abstract] [Full Text] [PDF]  

Victor I. Ilyin, James D. Pomonis, Garth T. Whiteside, James E. Harrison, Michelle S. Pearson, Lilly Mark, Paul I. Turchin, Susan Gottshall, Richard B. Carter, Phong Nguyen, Derk J. Hogenkamp, Shakira Olanrewaju, Elfrida Benjamin, and Richard M. Woodward
Pharmacology of 2-[4-(4-Chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: A Potent, Broad-Spectrum State-Dependent Sodium Channel Blocker for Treating Pain States
J Pharmacol Exp Ther 2006 318: 1083-1093. Published online May 25, 2006; 10.1124/jpet.106.104737 [Abstract] [Full Text] [PDF]  

Brandon C. Drafts and Janet L. Fisher
Identification of Structures within GABAA Receptor {alpha} Subunits That Regulate the Agonist Action of Pentobarbital
J Pharmacol Exp Ther 2006 318: 1094-1101. Published online May 25, 2006; 10.1124/jpet.106.104844 [Abstract] [Full Text] [PDF]  

Lisa M. Broad, Ruud Zwart, Kathy H. Pearson, Martin Lee, Louise Wallace, Gordon I. McPhie, Renee Emkey, Sean P. Hollinshead, Colin P. Dell, S. Richard Baker, and Emanuele Sher
Identification and Pharmacological Profile of a New Class of Selective Nicotinic Acetylcholine Receptor Potentiators
J Pharmacol Exp Ther 2006 318: 1108-1117. Published online May 31, 2006; 10.1124/jpet.106.104505 [Abstract] [Full Text] [PDF]  

Sarah B. Appel, Leon Wise, John McDaid, Susumu Koyama, Maureen A. McElvain, and Mark S. Brodie
The Effects of Long Chain-Length n-Alcohols on the Firing Frequency of Dopaminergic Neurons of the Ventral Tegmental Area
J Pharmacol Exp Ther 2006 318: 1137-1145. Published online June 1, 2006; 10.1124/jpet.106.105148 [Abstract] [Full Text] [PDF]  

Billy R. Martin, Jenny L. Wiley, Irina Beletskaya, Laura J. Sim-Selley, Forrest L. Smith, William L. Dewey, Jean Cottney, Julia Adams, James Baker, David Hill, Bijali Saha, John Zerkowski, Anu Mahadevan, and Raj K. Razdan
Pharmacological Characterization of Novel Water-Soluble Cannabinoids
J Pharmacol Exp Ther 2006 318: 1230-1239. Published online June 6, 2006; 10.1124/jpet.106.104109 [Abstract] [Full Text] [PDF]  

E. Dvir, J. E. Friedman, J. Y. Lee, J. Y. Koh, F. Younis, S. Raz, I. Shapiro, A. Hoffman, A. Dahan, G. Rosenberg, I. Angel, A. Kozak, and R. Duvdevani
A Novel Phospholipid Derivative of Indomethacin, DP-155 [Mixture of 1-Steroyl and 1-Palmitoyl-2-{6-[1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetamido]hexanoyl}-sn-glycero-3-phosophatidyl Choline], Shows Superior Safety and Similar Efficacy in Reducing Brain Amyloid beta in an Alzheimer's Disease Model
J Pharmacol Exp Ther 2006 318: 1248-1256. Published online June 8, 2006; 10.1124/jpet.106.103184 [Abstract] [Full Text] [PDF] [Erratum]   

E. E. Codd, J. R. Carson, R. W. Colburn, S. L. Dax, D. Desai-Krieger, R. P. Martinez, L. A. McKown, L. A. Neilson, P. M. Pitis, P. L. Stahle, D. J. Stone, A. J. Streeter, W. N. Wu, and S. P. Zhang
The Novel, Orally Active, Delta Opioid RWJ-394674 Is Biotransformed to the Potent Mu Opioid RWJ-413216
J Pharmacol Exp Ther 2006 318: 1273-1279. Published online June 9, 2006; 10.1124/jpet.106.104208 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:Back

Kristini K. Miles, Fay K. Kessler, Laura J. Webb, Philip C. Smith, and Joseph K. Ritter
Adenovirus-Mediated Gene Therapy to Restore Expression and Functionality of Multiple UDP-Glucuronosyltransferase 1A Enzymes in Gunn Rat Liver
J Pharmacol Exp Ther 2006 318: 1240-1247. Published online June 8, 2006; 10.1124/jpet.106.104810 [Abstract] [Full Text] [PDF]  

ERRATUM:Back

Correction to "Interactions of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures"
J Pharmacol Exp Ther 2006 318: 1388. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:Back

About the cover: Energy-based docking of BG into models of P450 2B6 and 3A5: differential exposure of geranyl side chain atoms. See the article by Kent et al. on page 992 of this issue.



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