PERSPECTIVES IN PHARMACOLOGY:

Genovefa D. Kolovou, Klelia D. Salpea, Katherine K. Anagnostopoulou, and Dimitri P. Mikhailidis

Alcohol Use, Vascular Disease, and Lipid-Lowering Drugs
J Pharmacol Exp Ther 2006 318: 1-7. Published online April 20, 2006; 10.1124/jpet.106.102269 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

F. Porreca, T. W. Vanderah, W. Guo, M. Barth, P. Dodey, V. Peyrou, J. M. Luccarini, J.-L. Junien, and D. Pruneau

Antinociceptive Pharmacology of N-[[4-(4,5-Dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide, Fumarate (LF22-0542), a Novel Nonpeptidic Bradykinin B₁ Receptor Antagonist
J Pharmacol Exp Ther 2006 318: 195-205. Published online March 24, 2006; 10.1124/jpet.105.098368 [Abstract] [Full Text] [PDF]  

G. Winger, C. M. Galuska, S. R. Hursh, and J. H. Woods

Relative Reinforcing Effects of Cocaine, Remifentanil, and Their Combination in Rhesus Monkeys
J Pharmacol Exp Ther 2006 318: 223-229. Published online March 29, 2006; 10.1124/jpet.105.100461 [Abstract] [Full Text] [PDF]  

Shinjae Chung, Sigrun Pohl, Joanne Zeng, Olivier Civelli, and Rainer K. Reinscheid

Endogenous Orphanin FQ/Nociceptin Is Involved in the Development of Morphine Tolerance
J Pharmacol Exp Ther 2006 318: 262-267. Published online April 4, 2006; 10.1124/jpet.106.103960 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Wan-Chen Lo, Pei-Jung Lu, Wen-Yu Ho, Michael Hsiao, and Ching-Jiunn Tseng

Induction of Heme Oxygenase-1 Is Involved in Carbon Monoxide-Mediated Central Cardiovascular Regulation
J Pharmacol Exp Ther 2006 318: 8-16. Published online March 24, 2006; 10.1124/jpet.105.099051 [Abstract] [Full Text] [PDF]  

Ruijuan Wang, Toshiro Miura, Nozomu Harada, Ryosuke Kametani, Masaki Shibuya, Yasuhiro Fukagawa, Shuji Kawamura, Yasuhiro Ikeda, Masayuki Hara, and Masunori Matsuzaki

Pleiotropic Effects of the -Adrenoceptor Blocker Carvedilol on Calcium Regulation during Oxidative Stress-Induced Apoptosis in Cardiomyocytes
J Pharmacol Exp Ther 2006 318: 45-52. Published online April 12, 2006; 10.1124/jpet.105.099903 [Abstract] [Full Text] [PDF]  

J. Ruth Wu-Wong, William Noonan, Junli Ma, Doug Dixon, Masaki Nakane, Antoinette L. Bolin, Kristin A. Koch, Steve Postl, Sherry J. Morgan, and Glenn A. Reinhart

Role of Phosphorus and Vitamin D Analogs in the Pathogenesis of Vascular Calcification
J Pharmacol Exp Ther 2006 318: 90-98. Published online April 7, 2006; 10.1124/jpet.106.101261 [Abstract] [Full Text] [PDF]  

Sung-Sik Park, Hong Zhao, Yeongho Jang, Robert A. Mueller, and Zhelong Xu

N⁶-(3-Iodobenzyl)-adenosine-5'-N-methylcarboxamide Confers Cardioprotection at Reperfusion by Inhibiting Mitochondrial Permeability Transition Pore Opening via Glycogen Synthase Kinase 3
J Pharmacol Exp Ther 2006 318: 124-131. Published online April 12, 2006; 10.1124/jpet.106.101477 [Abstract] [Full Text] [PDF]  

Jacob Raphael, Suzan Abedat, Julia Rivo, Karen Meir, Ronen Beeri, Thea Pugatsch, Zhiyi Zuo, and Yaacov Gozal

Volatile Anesthetic Preconditioning Attenuates Myocardial Apoptosis in Rabbits after Regional Ischemia and Reperfusion via Akt Signaling and Modulation of Bcl-2 Family Proteins
J Pharmacol Exp Ther 2006 318: 186-194. Published online March 21, 2006; 10.1124/jpet.105.100537 [Abstract] [Full Text] [PDF]  

Yejia Song, John C. Shryock, Stefan Wagner, Lars S. Maier, and Luiz Belardinelli

Blocking Late Sodium Current Reduces Hydrogen Peroxide-Induced Arrhythmogenic Activity and Contractile Dysfunction
J Pharmacol Exp Ther 2006 318: 214-222. Published online March 24, 2006; 10.1124/jpet.106.101832 [Abstract] [Full Text] [PDF]  

Noha Nassar and Abdel A. Abdel-Rahman

Central Adenosine Signaling Plays a Key Role in Centrally Mediated Hypotension in Conscious Aortic Barodenervated Rats
J Pharmacol Exp Ther 2006 318: 255-261. Published online April 4, 2006; 10.1124/jpet.105.100495 [Abstract] [Full Text] [PDF]  

Yi Shi, David D. Ku, Ricky Y. K. Man, and Paul M. Vanhoutte

Augmented Endothelium-Derived Hyperpolarizing Factor-Mediated Relaxations Attenuate Endothelial Dysfunction in Femoral and Mesenteric, but Not in Carotid Arteries from Type I Diabetic Rats
J Pharmacol Exp Ther 2006 318: 276-281. Published online March 24, 2006; 10.1124/jpet.105.099739 [Abstract] [Full Text] [PDF]  

Liming Jin, Zhekang Ying, Rob H. P. Hilgers, Jia Yin, Xueying Zhao, John D. Imig, and R. Clinton Webb

Increased RhoA/Rho-Kinase Signaling Mediates Spontaneous Tone in Aorta from Angiotensin II-Induced Hypertensive Rats
J Pharmacol Exp Ther 2006 318: 288-295. Published online March 28, 2006; 10.1124/jpet.105.100735 [Abstract] [Full Text] [PDF]  

Hiroyuki Kinoshita, Toshiharu Azma, Hiroshi Iranami, Katsutoshi Nakahata, Yoshiki Kimoto, Mayuko Dojo, Osafumi Yuge, and Yoshio Hatano

Synthetic Peroxisome Proliferator-Activated Receptor- Agonists Restore Impaired Vasorelaxation via ATP-Sensitive K⁺ Channels by High Glucose
J Pharmacol Exp Ther 2006 318: 312-318. Published online March 30, 2006; 10.1124/jpet.106.100958 [Abstract] [Full Text] [PDF]  

Daisuke Nakano, Chol-Jun Kwak, Kiwako Fujii, Kenji Ikemura, Aiko Satake, Mamoru Ohkita, Masanori Takaoka, Yoshiko Ono, Masaaki Nakai, Namino Tomimori, Yoshinobu Kiso, and Yasuo Matsumura

Sesamin Metabolites Induce an Endothelial Nitric Oxide-Dependent Vasorelaxation through Their Antioxidative Property-Independent Mechanisms: Possible Involvement of the Metabolites in the Antihypertensive Effect of Sesamin
J Pharmacol Exp Ther 2006 318: 328-335. Published online April 5, 2006; 10.1124/jpet.105.100149 [Abstract] [Full Text] [PDF]  

Tommaso Angelone, Yannick Goumon, Maria Carmela Cerra, Marie-Hélène Metz-Boutigue, Dominique Aunis, and Bruno Tota

The Emerging Cardioinhibitory Role of the Hippocampal Cholinergic Neurostimulating Peptide
J Pharmacol Exp Ther 2006 318: 336-344. Published online April 11, 2006; 10.1124/jpet.106.102103 [Abstract] [Full Text] [PDF]  

Todd Wisialowski, Kimberly Crimin, Juntyma Engtrakul, John O'Donnell, Bernard Fermini, and Anthony A. Fossa

Differentiation of Arrhythmia Risk of the Antibacterials Moxifloxacin, Erythromycin, and Telithromycin Based on Analysis of Monophasic Action Potential Duration Alternans and Cardiac Instability
J Pharmacol Exp Ther 2006 318: 352-359. Published online April 13, 2006; 10.1124/jpet.106.101881 [Abstract] [Full Text] [PDF]  

Sharon L. Hale, Justin A. Leeka, and Robert A. Kloner

Improved Left Ventricular Function and Reduced Necrosis after Myocardial Ischemia/Reperfusion in Rabbits Treated with Ranolazine, an Inhibitor of the Late Sodium Channel
J Pharmacol Exp Ther 2006 318: 418-423. Published online April 14, 2006; 10.1124/jpet.106.103242 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

B. Frazier Taylor, Samuel C. McNeely, Heather L. Miller, Geniece M. Lehmann, Michael J. McCabe, Jr., and J. Christopher States

p53 Suppression of Arsenite-Induced Mitotic Catastrophe Is Mediated by p21^CIP1/WAF1
J Pharmacol Exp Ther 2006 318: 142-151. Published online April 13, 2006; 10.1124/jpet.106.103077 [Abstract] [Full Text] [PDF]  

Jin-Ah Kim, Jin-Yong Park, Ho-Won Kang, Sung-Un Huh, Seong-Woo Jeong, and Jung-Ha Lee

Augmentation of Ca_v3.2 T-Type Calcium Channel Activity by cAMP-Dependent Protein Kinase A
J Pharmacol Exp Ther 2006 318: 230-237. Published online March 28, 2006; 10.1124/jpet.106.101402 [Abstract] [Full Text] [PDF]  

Manickavasagom Alkondon and Edson X. Albuquerque

Subtype-Specific Inhibition of Nicotinic Acetylcholine Receptors by Choline: A Regulatory Pathway
J Pharmacol Exp Ther 2006 318: 268-275. Published online March 24, 2006; 10.1124/jpet.106.103135 [Abstract] [Full Text] [PDF]  

Andres A. Caro and Arthur I. Cederbaum

Role of Phosphatidylinositol 3-Kinase/AKT as a Survival Pathway against CYP2E1-Dependent Toxicity
J Pharmacol Exp Ther 2006 318: 360-372. Published online April 19, 2006; 10.1124/jpet.106.102921 [Abstract] [Full Text] [PDF]  

David Alonso-Escolano, Carlos Medina, Katarzyna Cieslik, Anna Radomski, Paul Jurasz, Maria José Santos-Martínez, Tilahum Jiffar, Peter Ruvolo, and Marek W. Radomski

Protein Kinase C Mediates Platelet-Induced Breast Cancer Cell Invasion
J Pharmacol Exp Ther 2006 318: 373-380. Published online April 14, 2006; 10.1124/jpet.106.103358 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Nadia Rucci, Irene Recchia, Adriano Angelucci, Marina Alamanou, Andrea Del Fattore, Dario Fortunati, Mira Susa, Doriano Fabbro, Mauro Bologna, and Anna Teti

Inhibition of Protein Kinase c-Src Reduces the Incidence of Breast Cancer Metastases and Increases Survival in Mice: Implications for Therapy
J Pharmacol Exp Ther 2006 318: 161-172. Published online April 20, 2006; 10.1124/jpet.106.102004 [Abstract] [Full Text] [PDF]  

Panagiota Zania, Sosanna Kritikou, Christodoulos S. Flordellis, Michael E. Maragoudakis, and Nikos E. Tsopanoglou

Blockade of Angiogenesis by Small Molecule Antagonists to Protease-Activated Receptor-1: Association with Endothelial Cell Growth Suppression and Induction of Apoptosis
J Pharmacol Exp Ther 2006 318: 246-254. Published online April 4, 2006; 10.1124/jpet.105.099069 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Ling Gao, Furong Wang, Bo Wang, Bendi Gong, Jie Zhang, Xiumei Zhang, and Jiajun Zhao

Cilostazol Protects Diabetic Rats from Vascular Inflammation via Nuclear Factor-B-Dependent Down-Regulation of Vascular Cell Adhesion Molecule-1 Expression
J Pharmacol Exp Ther 2006 318: 53-58. Published online April 4, 2006; 10.1124/jpet.106.101444 [Abstract] [Full Text] [PDF]  

Satyanarayana Medicherla, Andrew A. Protter, Jing Ying Ma, Ruban Mangadu, Ramona Almirez, Bruce Koppelman, Irene Kerr, Tony A. Navas, Fabiola Movius, Mamatha Reddy, Yu-Wang Liu, Gregory Luedtke, John Perumattam, Babu Mavunkel, Sundeep Dugar, and George F. Schreiner

Preventive and Therapeutic Potential of p38-Selective Mitogen-Activated Protein Kinase Inhibitor in Nonobese Diabetic Mice with Type 1 Diabetes
J Pharmacol Exp Ther 2006 318: 99-107. Published online April 7, 2006; 10.1124/jpet.105.097857 [Abstract] [Full Text] [PDF]  

Guohong Liu, Sarah Melissa P. Jacobo, Nathan Hilliard, and Gregory H. Hockerman

Differential Modulation of Ca_v1.2 and Ca_v1.3-Mediated Glucose-Stimulated Insulin Secretion by cAMP in INS-1 Cells: Distinct Roles for Exchange Protein Directly Activated by cAMP 2 (Epac2) and Protein Kinase A
J Pharmacol Exp Ther 2006 318: 152-160. Published online March 24, 2006; 10.1124/jpet.105.097477 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Rina Aharoni, Basak Kayhan, Ori Brenner, Hagit Domev, Galya Labunskay, and Ruth Arnon

Immunomodulatory Therapeutic Effect of Glatiramer Acetate on Several Murine Models of Inflammatory Bowel Disease
J Pharmacol Exp Ther 2006 318: 68-78. Published online April 19, 2006; 10.1124/jpet.106.103192 [Abstract] [Full Text] [PDF]  

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA:

Ru Zhou, Wei Tang, Yong-Xin Ren, Pei-Lan He, Fan Zhang, Li-Ping Shi, Yun-Feng Fu, Yuan-Chao Li, Shiro Ono, Hiromi Fujiwara, Yi-Fu Yang, and Jian-Ping Zuo

(5R)-5-Hydroxytriptolide Attenuated Collagen-Induced Arthritis in DBA/1 Mice via Suppressing Interferon- Production and Its Related Signaling
J Pharmacol Exp Ther 2006 318: 35-44. Published online March 30, 2006; 10.1124/jpet.106.101113 [Abstract] [Full Text] [PDF]  

Mirentxu I. Iruretagoyena, Sofía E. Sepúlveda, J. Pablo Lezana, Marcela Hermoso, Miguel Bronfman, Miguel A. Gutiérrez, Sergio H. Jacobelli, and Alexis M. Kalergis

Inhibition of Nuclear Factor-B Enhances the Capacity of Immature Dendritic Cells to Induce Antigen-Specific Tolerance in Experimental Autoimmune Encephalomyelitis
J Pharmacol Exp Ther 2006 318: 59-67. Published online April 5, 2006; 10.1124/jpet.106.103259 [Abstract] [Full Text] [PDF]  

Salvatore Cuzzocrea, Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Carmelo Muià, Marika Collin, Emanuela Esposito, Placido Bramanti, and Christoph Thiemermann

Glycogen Synthase Kinase-3 Inhibition Reduces Secondary Damage in Experimental Spinal Cord Trauma
J Pharmacol Exp Ther 2006 318: 79-89. Published online April 6, 2006; 10.1124/jpet.106.102863 [Abstract] [Full Text] [PDF]  

Satyanarayana Medicherla, Jing Ying Ma, Ruban Mangadu, Yebin Jiang, Jenny J. Zhao, Ramona Almirez, Irene Kerr, Elizabeth G. Stebbins, Gilbert O'Young, Ann M. Kapoun, Gregory Luedtke, Sarvajit Chakravarty, Sundeep Dugar, Harry K. Genant, and Andrew A. Protter

A Selective p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis
J Pharmacol Exp Ther 2006 318: 132-141. Published online April 5, 2006; 10.1124/jpet.105.098020 [Abstract] [Full Text] [PDF]  

Robert Fürst, Signe B. Blumenthal, Alexandra K. Kiemer, Stefan Zahler, and Angelika M. Vollmar

Nuclear Factor-B-Independent Anti-Inflammatory Action of Salicylate in Human Endothelial Cells: Induction of Heme Oxygenase-1 by the c-Jun N-Terminal Kinase/Activator Protein-1 Pathway
J Pharmacol Exp Ther 2006 318: 389-394. Published online April 19, 2006; 10.1124/jpet.106.102251 [Abstract] [Full Text] [PDF]  

Anuk M. Das, Krishna G. Vaddi, Kimberly A. Solomon, Candice Krauthauser, Xiaosui Jiang, Kim W. McIntyre, Xiao Xia Yang, Eric Wadman, Patricia Welch, Maryanne Covington, Danielle Graden, Krishnaswamy Yeleswaram, James M. Trzaskos, Robert C. Newton, Sandhya Mandlekar, Soo S. Ko, Percy H. Carter, and Paul Davies

Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CC Chemokine Receptor 3 Antagonists in Mouse Models of Allergic Inflammation
J Pharmacol Exp Ther 2006 318: 411-417. Published online April 13, 2006; 10.1124/jpet.105.099812 [Abstract] [Full Text] [PDF]  

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS:

M. L. H. Vlaming, K. Mohrmann, E. Wagenaar, D. R. de Waart, R. P. J. Oude Elferink, J. S. Lagas, O. van Tellingen, L. D. Vainchtein, H. Rosing, J. H. Beijnen, J. H. M. Schellens, and A. H. Schinkel

Carcinogen and Anticancer Drug Transport by Mrp2 in Vivo: Studies Using Mrp2 (Abcc2) Knockout Mice
J Pharmacol Exp Ther 2006 318: 319-327. Published online April 12, 2006; 10.1124/jpet.106.101774 [Abstract] [Full Text] [PDF] [Data Supplement]   

Namandjé N. Bumpus, Ute M. Kent, and Paul F. Hollenberg

Metabolism of Efavirenz and 8-Hydroxyefavirenz by P450 2B6 Leads to Inactivation by Two Distinct Mechanisms
J Pharmacol Exp Ther 2006 318: 345-351. Published online April 12, 2006; 10.1124/jpet.106.102525 [Abstract] [Full Text] [PDF]  

Lichuan Liu, Yunhai Cui, Alfred Y. Chung, Yoshihisa Shitara, Yuichi Sugiyama, Dietrich Keppler, and K. Sandy Pang

Vectorial Transport of Enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in Rat and Human Livers
J Pharmacol Exp Ther 2006 318: 395-402. Published online April 20, 2006; 10.1124/jpet.106.103390 [Abstract] [Full Text] [PDF]  

Emanuela Salvatorelli, Pierantonio Menna, Sabrina Cascegna, Giovanni Liberi, Antonio M. Calafiore, Luca Gianni, and Giorgio Minotti

Paclitaxel and Docetaxel Stimulation of Doxorubicinol Formation in the Human Heart: Implications for Cardiotoxicity of Doxorubicin-Taxane Chemotherapies
J Pharmacol Exp Ther 2006 318: 424-433. Published online April 13, 2006; 10.1124/jpet.106.103846 [Abstract] [Full Text] [PDF]  

Masahiro Tsuda, Tomohiro Terada, Megumi Irie, Toshiya Katsura, Ayumu Niida, Kenji Tomita, Nobutaka Fujii, and Ken-ichi Inui

Transport Characteristics of a Novel Peptide Transporter 1 Substrate, Antihypotensive Drug Midodrine, and Its Amino Acid Derivatives
J Pharmacol Exp Ther 2006 318: 455-460. Published online April 5, 2006; 10.1124/jpet.106.102830 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Karunya K. Kandimalla, Geoffry L. Curran, Silvina S. Holasek, Emily J. Gilles, Thomas M. Wengenack, Marina Ramirez-Alvarado, and Joseph F. Poduslo

Physiological and Biophysical Factors That Influence Alzheimer's Disease Amyloid Plaque Targeting of Native and Putrescine Modified Human Amyloid 40
J Pharmacol Exp Ther 2006 318: 17-25. Published online March 24, 2006; 10.1124/jpet.105.095711 [Abstract] [Full Text] [PDF]  

Feride Cengelli, Dusica Maysinger, Florianne Tschudi-Monnet, Xavier Montet, Claire Corot, Alke Petri-Fink, Heinrich Hofmann, and Lucienne Juillerat-Jeanneret

Interaction of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures
J Pharmacol Exp Ther 2006 318: 108-116. Published online April 11, 2006; 10.1124/jpet.106.101915 [Abstract] [Full Text] [PDF] [Erratum]   

Ruggero Galici, Carrie K. Jones, Kamondanai Hemstapat, Yi Nong, Nicholas G. Echemendia, Lilly C. Williams, Tomas de Paulis, and P. Jeffrey Conn

Biphenyl-indanone A, a Positive Allosteric Modulator of the Metabotropic Glutamate Receptor Subtype 2, Has Antipsychotic- and Anxiolytic-Like Effects in Mice
J Pharmacol Exp Ther 2006 318: 173-185. Published online April 11, 2006; 10.1124/jpet.106.102046 [Abstract] [Full Text] [PDF]  

Tatsuo Yamamoto, Koyo Shono, and Serabi Tanabe

Buprenorphine Activates µ and Opioid Receptor Like-1 Receptors Simultaneously, but the Analgesic Effect Is Mainly Mediated by µ Receptor Activation in the Rat Formalin Test
J Pharmacol Exp Ther 2006 318: 206-213. Published online March 24, 2006; 10.1124/jpet.105.100859 [Abstract] [Full Text] [PDF]  

Ying-Shan Han, Stéphane Bastianetto, Yvan Dumont, and Rémi Quirion

Specific Plasma Membrane Binding Sites for Polyphenols, Including Resveratrol, in the Rat Brain
J Pharmacol Exp Ther 2006 318: 238-245. Published online March 30, 2006; 10.1124/jpet.106.102319 [Abstract] [Full Text] [PDF]  

Gang Yu, Yong-Juan Yue, Meng-Xun Cui, and Ze-Hui Gong

Thienorphine Is a Potent Long-Acting Partial Opioid Agonist: A Comparative Study with Buprenorphine
J Pharmacol Exp Ther 2006 318: 282-287. Published online March 28, 2006; 10.1124/jpet.105.099937 [Abstract] [Full Text] [PDF]  

Sachin Patel and Cecilia J. Hillard

Pharmacological Evaluation of Cannabinoid Receptor Ligands in a Mouse Model of Anxiety: Further Evidence for an Anxiolytic Role for Endogenous Cannabinoid Signaling
J Pharmacol Exp Ther 2006 318: 304-311. Published online March 28, 2006; 10.1124/jpet.106.101287 [Abstract] [Full Text] [PDF]  

Sarah E. McCallum, Neeraja Parameswaran, Tanuja Bordia, Hong Fan, J. Michael McIntosh, and Maryka Quik

Differential Regulation of Mesolimbic 3/62 and 42 Nicotinic Acetylcholine Receptor Sites and Function after Long-Term Oral Nicotine to Monkeys
J Pharmacol Exp Ther 2006 318: 381-388. Published online April 18, 2006; 10.1124/jpet.106.104414 [Abstract] [Full Text] [PDF]  

Junichi Ogata, Munehiro Shiraishi, Tsunehisa Namba, C. Thetford Smothers, John J. Woodward, and R. Adron Harris

Effects of Anesthetics on Mutant N-Methyl-D-Aspartate Receptors Expressed in Xenopus Oocytes
J Pharmacol Exp Ther 2006 318: 434-443. Published online April 18, 2006; 10.1124/jpet.106.101691 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Sree D. Panuganti, Farah D. Khan, and Craig K. Svensson

Enhanced Xenobiotic-Induced Hepatotoxicity and Kupffer Cell Activation by Restraint-Induced Stress
J Pharmacol Exp Ther 2006 318: 26-34. Published online March 28, 2006; 10.1124/jpet.106.100933 [Abstract] [Full Text] [PDF]  

Jonathan M. DiFabio, George R. Thomas, Liana Zucco, Michael A. Kuliszewski, Brian M. Bennett, Michael J. Kutryk, and John D. Parker

Nitroglycerin Attenuates Human Endothelial Progenitor Cell Differentiation, Function, and Survival
J Pharmacol Exp Ther 2006 318: 117-123. Published online April 18, 2006; 10.1124/jpet.106.102129 [Abstract] [Full Text] [PDF]  

Takamasa Ohashi, Yasushi Ito, Tadakatsu Matsuno, Shinji Sato, Kaoru Shimokata, and Hiroaki Kume

Paradoxical Effects of Hydrogen Peroxide on Human Airway Anion Secretion
J Pharmacol Exp Ther 2006 318: 296-303. Published online March 28, 2006; 10.1124/jpet.106.102541 [Abstract] [Full Text] [PDF]  

Philip Sawle, Jehad Hammad, Ian J. S. Fairlamb, Benjamin Moulton, Ciara T. O'Brien, Jason M. Lynam, Anne K. Duhme-Klair, Roberta Foresti, and Roberto Motterlini

Bioactive Properties of Iron-Containing Carbon Monoxide-Releasing Molecules
J Pharmacol Exp Ther 2006 318: 403-410. Published online April 7, 2006; 10.1124/jpet.106.101758 [Abstract] [Full Text] [PDF]  

Alain Berson, Sophie Cazanave, Véronique Descatoire, Marina Tinel, Alain Grodet, Claude Wolf, Gérard Feldmann, and Dominique Pessayre

The Anti-Inflammatory Drug, Nimesulide (4-Nitro-2-phenoxymethane-sulfoanilide), Uncouples Mitochondria and Induces Mitochondrial Permeability Transition in Human Hepatoma Cells: Protection by Albumin
J Pharmacol Exp Ther 2006 318: 444-454. Published online April 14, 2006; 10.1124/jpet.106.104125 [Abstract] [Full Text] [PDF]  

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