ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Harunobu Tahara, Hiroyuki Kusuhara, Michihiro Chida, Eiichi Fuse, and Yuichi Sugiyama

Is the Monkey an Appropriate Animal Model to Examine Drug-Drug Interactions Involving Renal Clearance? Effect of Probenecid on the Renal Elimination of H₂ Receptor Antagonists
J Pharmacol Exp Ther 2006 316: 1187-1194. Published online November 16, 2005; 10.1124/jpet.105.094052 [Abstract] [Full Text] [PDF]  

Anita A. Mathias, Lillian Maggio-Price, Yurong Lai, Anshul Gupta, and Jashvant D. Unadkat

Changes in Pharmacokinetics of Anti-HIV Protease Inhibitors during Pregnancy: The Role of CYP3A and P-glycoprotein
J Pharmacol Exp Ther 2006 316: 1202-1209. Published online November 17, 2005; 10.1124/jpet.105.095406 [Abstract] [Full Text] [PDF]  

Scott G. Summerfield, Alexander J. Stevens, Leanne Cutler, Maria del Carmen Osuna, Beverley Hammond, Sac-Pham Tang, Ann Hersey, David J. Spalding, and Phil Jeffrey

Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain
J Pharmacol Exp Ther 2006 316: 1282-1290. Published online December 5, 2005; 10.1124/jpet.105.092916 [Abstract] [Full Text] [PDF]  

Stephan Steckelbroeck, Busola Oyesanmi, Yi Jin, Seon-Hwa Lee, Helenius J. Kloosterboer, and Trevor M. Penning

Tibolone Metabolism in Human Liver Is Catalyzed by 3/3-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily
J Pharmacol Exp Ther 2006 316: 1300-1309. Published online December 8, 2005; 10.1124/jpet.105.091587 [Abstract] [Full Text] [PDF]  

Zhengbo Duanmu, Amy Weckle, Sevasti B. Koukouritaki, Ronald N. Hines, Josie L. Falany, Charles N. Falany, Thomas A. Kocarek, and Melissa Runge-Morris

Developmental Expression of Aryl, Estrogen, and Hydroxysteroid Sulfotransferases in Pre- and Postnatal Human Liver
J Pharmacol Exp Ther 2006 316: 1310-1317. Published online December 9, 2005; 10.1124/jpet.105.093633 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Elizabeth M. Peckham and John R. Traynor

Comparison of the Antinociceptive Response to Morphine and Morphine-Like Compounds in Male and Female Sprague-Dawley Rats
J Pharmacol Exp Ther 2006 316: 1195-1201. Published online November 16, 2005; 10.1124/jpet.105.094276 [Abstract] [Full Text] [PDF]  

N. R. Mirza, R. J. Rodgers, and L. S. Mathiasen

Comparative Cue Generalization Profiles of L-838, 417, SL651498, Zolpidem, CL218,872, Ocinaplon, Bretazenil, Zopiclone, and Various Benzodiazepines in Chlordiazepoxide and Zolpidem Drug Discrimination
J Pharmacol Exp Ther 2006 316: 1291-1299. Published online December 8, 2005; 10.1124/jpet.105.094003 [Abstract] [Full Text] [PDF]  

N. R. Mirza and E. Ø. Nielsen

Do Subtype-Selective -Aminobutyric Acid_A Receptor Modulators Have a Reduced Propensity to Induce Physical Dependence in Mice?
J Pharmacol Exp Ther 2006 316: 1378-1385. Published online December 13, 2005; 10.1124/jpet.105.094474 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Chanil Moon, Melissa Krawczyk, Doojin Paik, Thomas Coleman, Michael Brines, Magdalena Juhaszova, Steven J. Sollott, Edward G. Lakatta, and Mark I. Talan

Erythropoietin, Modified to Not Stimulate Red Blood Cell Production, Retains Its Cardioprotective Properties
J Pharmacol Exp Ther 2006 316: 999-1005. Published online November 23, 2005; 10.1124/jpet.105.094854 [Abstract] [Full Text] [PDF]  

Guichun Han, Xiuping Yu, Luo Lu, Shuyi Li, Handong Ma, Shu Zhu, Xiuyun Cui, and Richard E. White

Estrogen Receptor Mediates Acute Potassium Channel Stimulation in Human Coronary Artery Smooth Muscle Cells
J Pharmacol Exp Ther 2006 316: 1025-1030. Published online November 18, 2005; 10.1124/jpet.105.093542 [Abstract] [Full Text] [PDF]  

Alexander N. Katchman, John Koerner, Toshimasa Tosaka, Raymond L. Woosley, and Steven N. Ebert

Comparative Evaluation of HERG Currents and QT Intervals following Challenge with Suspected Torsadogenic and Nontorsadogenic Drugs
J Pharmacol Exp Ther 2006 316: 1098-1106. Published online November 8, 2005; 10.1124/jpet.105.093393 [Abstract] [Full Text] [PDF]  

S. G. Burke, C. L. Wainwright, I. Vojnovic, T. Warner, D. G. Watson, and B. L. Furman

The Effect of NCX4016 [2-Acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl Ester] on the Consequences of Ischemia and Reperfusion in the Streptozotocin Diabetic Rat
J Pharmacol Exp Ther 2006 316: 1107-1114. Published online October 31, 2005; 10.1124/jpet.105.096339 [Abstract] [Full Text] [PDF]  

Martine Clozel, Patrick Hess, Changbin Qiu, Shuang-Shuang Ding, and Markus Rey

The Urotensin-II Receptor Antagonist Palosuran Improves Pancreatic and Renal Function in Diabetic Rats
J Pharmacol Exp Ther 2006 316: 1115-1121. Published online November 2, 2005; 10.1124/jpet.105.094821 [Abstract] [Full Text] [PDF]  

Kumkum Ganguly, Mukul S. Goel, Tatyana Krasik, Khalil Bdeir, Scott L. Diamond, Douglas B. Cines, Vladimir R. Muzykantov, and Juan-Carlos Murciano

Fibrin Affinity of Erythrocyte-Coupled Tissue-Type Plasminogen Activators Endures Hemodynamic Forces and Enhances Fibrinolysis in Vivo
J Pharmacol Exp Ther 2006 316: 1130-1136. Published online November 11, 2005; 10.1124/jpet.105.093450 [Abstract] [Full Text] [PDF]  

Sinisa Stanisavljevic, Tatjana Ignjatovic, Peter A. Deddish, Viktor Brovkovych, Kai Zhang, Ervin G. Erdös, and Randal A. Skidgel

Angiotensin I-Converting Enzyme Inhibitors Block Protein Kinase C by Activating Bradykinin B₁ Receptors in Human Endothelial Cells
J Pharmacol Exp Ther 2006 316: 1153-1158. Published online November 10, 2005; 10.1124/jpet.105.093849 [Abstract] [Full Text] [PDF]  

YouYou Zhao, David Bell, Lisa R. Smith, Li Zhao, Adrian B. Devine, Eugene M. McHenry, D. Paul Nicholls, and Barbara J. McDermott

Differential Expression of Components of the Cardiomyocyte Adrenomedullin/Intermedin Receptor System following Blood Pressure Reduction in Nitric Oxide-Deficient Hypertension
J Pharmacol Exp Ther 2006 316: 1269-1281. Published online December 2, 2005; 10.1124/jpet.105.092783 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Tzu-Hsuan Huang and Sherie L. Morrison

A Trimeric Anti-HER2/neu ScFv and Tumor Necrosis Factor- Fusion Protein Induces HER2/neu Signaling and Facilitates Repair of Injured Epithelia
J Pharmacol Exp Ther 2006 316: 983-991. Published online November 15, 2005; 10.1124/jpet.105.095513 [Abstract] [Full Text] [PDF] [Data Supplement]   

Annette Hambrock, Claudia Bernardo de Oliveira Franz, Sabrina Hiller, and Hartmut Osswald

Glibenclamide-Induced Apoptosis Is Specifically Enhanced by Expression of the Sulfonylurea Receptor Isoform SUR1 but Not by Expression of SUR2B or the Mutant SUR1(M1289T)
J Pharmacol Exp Ther 2006 316: 1031-1037. Published online November 23, 2005; 10.1124/jpet.105.097501 [Abstract] [Full Text] [PDF]  

Elvira V. Dzhura, Wenjuan He, and Kevin P. M. Currie

Linopirdine Modulates Calcium Signaling and Stimulus-Secretion Coupling in Adrenal Chromaffin Cells by Targeting M-Type K⁺ Channels and Nicotinic Acetylcholine Receptors
J Pharmacol Exp Ther 2006 316: 1165-1174. Published online November 9, 2005; 10.1124/jpet.105.095570 [Abstract] [Full Text] [PDF]  

Susanne Rösch, Robert Ramer, Kay Brune, and Burkhard Hinz

R(+)-Methanandamide and Other Cannabinoids Induce the Expression of Cyclooxygenase-2 and Matrix Metalloproteinases in Human Nonpigmented Ciliary Epithelial Cells
J Pharmacol Exp Ther 2006 316: 1219-1228. Published online December 5, 2005; 10.1124/jpet.105.092858 [Abstract] [Full Text] [PDF]  

Sang K. Kim, Mohamed A. Abdelmegeed, and Raymond F. Novak

Identification of the Insulin Signaling Cascade in the Regulation of Alpha-Class Glutathione S-Transferase Expression in Primary Cultured Rat Hepatocytes
J Pharmacol Exp Ther 2006 316: 1255-1261. Published online November 17, 2005; 10.1124/jpet.105.096065 [Abstract] [Full Text] [PDF]  

Mia Engström, Juha-Matti Savola, and Siegfried Wurster

Differential Efficacies of Somatostatin Receptor Agonists for G-Protein Activation and Desensitization of Somatostatin Receptor Subtype 4-Mediated Responses
J Pharmacol Exp Ther 2006 316: 1262-1268. Published online November 15, 2005; 10.1124/jpet.105.094128 [Abstract] [Full Text] [PDF]  

Connie Cheung, Ai-Ming Yu, Chong-Sheng Chen, Kristopher W. Krausz, Linda G. Byrd, Lionel Feigenbaum, Robert J. Edwards, David J. Waxman, and Frank J. Gonzalez

Growth Hormone Determines Sexual Dimorphism of Hepatic Cytochrome P450 3A4 Expression in Transgenic Mice
J Pharmacol Exp Ther 2006 316: 1328-1334. Published online November 16, 2005; 10.1124/jpet.105.094367 [Abstract] [Full Text] [PDF]  

Yuling Chi, Sonya M. Khersonsky, Young-Tae Chang, and Victor L. Schuster

Identification of a New Class of Prostaglandin Transporter Inhibitors and Characterization of Their Biological Effects on Prostaglandin E₂ Transport
J Pharmacol Exp Ther 2006 316: 1346-1350. Published online November 3, 2005; 10.1124/jpet.105.091975 [Abstract] [Full Text] [PDF] [Data Supplement]   

Ying Mu, Jinnan Zhang, Shimin Zhang, Hong-Hao Zhou, David Toma, Songrong Ren, Leaf Huang, Maria Yaramus, Andrew Baum, Raman Venkataramanan, and Wen Xie

Traditional Chinese Medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) Activate Pregnane X Receptor and Increase Warfarin Clearance in Rats
J Pharmacol Exp Ther 2006 316: 1369-1377. Published online November 2, 2005; 10.1124/jpet.105.094342 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Sonia S. Dharap, Pooja Chandna, Yang Wang, Jayant J. Khandare, Bo Qiu, Stanley Stein, and Tamara Minko

Molecular Targeting of BCL2 and BCLXL Proteins by Synthetic BCL2 Homology 3 Domain Peptide Enhances the Efficacy of Chemotherapy
J Pharmacol Exp Ther 2006 316: 992-998. Published online November 15, 2005; 10.1124/jpet.105.094243 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Joy K. Saha, Jinqi Xia, Steven K. Engle, Yun-Fei Chen, Wolfgang Glaesner, and Joseph A. Jakubowski

A Model of Controlled Acute Hyperglycemia in Rats: Effects of Insulin and Glucagon-Like Peptide-1 Analog
J Pharmacol Exp Ther 2006 316: 1159-1164. Published online November 9, 2005; 10.1124/jpet.105.093534 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Atsushi Nakajima, Kyoko Ueda, Masanori Takaoka, Yoshiko Yoshimi, and Yasuo Matsumura

Opposite Effects of Pre- and Postischemic Treatments with Nitric Oxide Donor on Ischemia/Reperfusion-Induced Renal Injury
J Pharmacol Exp Ther 2006 316: 1038-1046. Published online November 23, 2005; 10.1124/jpet.105.092049 [Abstract] [Full Text] [PDF]  

Naoki Kondo, Hideyasu Kiyomoto, Tokunori Yamamoto, Akira Miyatake, Guang-Ping Sun, Matlubur Rahman, Hirofumi Hitomi, Kumiko Moriwaki, Taiga Hara, Shoji Kimura, Youichi Abe, Masakazu Kohno, and Akira Nishiyama

Effects of Calcium Channel Blockade on Angiotensin II-Induced Peritubular Ischemia in Rats
J Pharmacol Exp Ther 2006 316: 1047-1052. Published online November 30, 2005; 10.1124/jpet.105.095331 [Abstract] [Full Text] [PDF]  

Ina Bergheim, James P. Luyendyk, Chad Steele, Gilandra K. Russell, Luping Guo, Robert A. Roth, and Gavin E. Arteel

Metformin Prevents Endotoxin-Induced Liver Injury after Partial Hepatectomy
J Pharmacol Exp Ther 2006 316: 1053-1061. Published online December 1, 2005; 10.1124/jpet.105.092122 [Abstract] [Full Text] [PDF]  

Ricard Farré, Mariona Aulí, Begoña Lecea, Emma Martínez, and Pere Clavé

Pharmacologic Characterization of Intrinsic Mechanisms Controlling Tone and Relaxation of Porcine Lower Esophageal Sphincter
J Pharmacol Exp Ther 2006 316: 1238-1248. Published online November 22, 2005; 10.1124/jpet.105.094482 [Abstract] [Full Text] [PDF]  

Pu Duann, Prasun K. Datta, Cynthia Pan, Jeffrey B. Blumberg, Mukut Sharma, and Elias A. Lianos

Superoxide Dismutase Mimetic Preserves the Glomerular Capillary Permeability Barrier to Protein
J Pharmacol Exp Ther 2006 316: 1249-1254. Published online November 22, 2005; 10.1124/jpet.105.092957 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Carmelo Muià, Placido Bramanti, and Salvatore Cuzzocrea

Immunomodulatory Effects of Etanercept in an Experimental Model of Spinal Cord Injury
J Pharmacol Exp Ther 2006 316: 1006-1016. Published online November 22, 2005; 10.1124/jpet.105.097188 [Abstract] [Full Text] [PDF]  

Elizabeth B. Kelso, John C. Lockhart, Todd Hembrough, Lynette Dunning, Robin Plevin, Morley D. Hollenberg, Christian P. Sommerhoff, John S. McLean, and William R. Ferrell

Therapeutic Promise of Proteinase-Activated Receptor-2 Antagonism in Joint Inflammation
J Pharmacol Exp Ther 2006 316: 1017-1024. Published online October 31, 2005; 10.1124/jpet.105.093807 [Abstract] [Full Text] [PDF]  

Meaghan E. Killeen, Joshua A. Englert, Donna Beer Stolz, Mingchen Song, Yusheng Han, Russell L. Delude, John A. Kellum, and Mitchell P. Fink

The Phase 2 Enzyme Inducers Ethacrynic Acid, DL-Sulforaphane, and Oltipraz Inhibit Lipopolysaccharide-Induced High-Mobility Group Box 1 Secretion by RAW 264.7 Cells
J Pharmacol Exp Ther 2006 316: 1070-1079. Published online December 28, 2005; 10.1124/jpet.105.092841 [Abstract] [Full Text] [PDF]  

Yun-Feng Fu, Jun-Xia Wang, Yang Zhao, Yang Yang, Wei Tang, Jia Ni, Yi-Na Zhu, Ru Zhou, Pei-Lan He, Chuan Li, Xiao-Yu Li, Yi-Fu Yang, Brian R. Lawson, and Jian-Ping Zuo

S-Adenosyl-L-homocysteine Hydrolase Inactivation Curtails Ovalbumin-Induced Immune Responses
J Pharmacol Exp Ther 2006 316: 1229-1237. Published online December 2, 2005; 10.1124/jpet.105.093369 [Abstract] [Full Text] [PDF]  

Mark A. Birrell, Sissie Wong, Kerryn McCluskie, Matthew C. Catley, Elizabeth L. Hardaker, Saleem Haj-Yahia, and Maria G. Belvisi

Second-Generation Inhibitors Demonstrate the Involvement of p38 Mitogen-Activated Protein Kinase in Post-Transcriptional Modulation of Inflammatory Mediator Production in Human and Rodent Airways
J Pharmacol Exp Ther 2006 316: 1318-1327. Published online December 20, 2005; 10.1124/jpet.105.093310 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Sabatino Maione, Tiziana Bisogno, Vito de Novellis, Enza Palazzo, Luigia Cristino, Marta Valenti, Stefania Petrosino, Vittorio Guglielmotti, Francesco Rossi, and Vincenzo Di Marzo

Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors
J Pharmacol Exp Ther 2006 316: 969-982. Published online November 11, 2005; 10.1124/jpet.105.093286 [Abstract] [Full Text] [PDF]  

Nadine N. Johnson-Farley, Tatyana Travkina, and Daniel S. Cowen

Cumulative Activation of Akt and Consequent Inhibition of Glycogen Synthase Kinase-3 by Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor-1 in Cultured Hippocampal Neurons
J Pharmacol Exp Ther 2006 316: 1062-1069. Published online November 11, 2005; 10.1124/jpet.105.094433 [Abstract] [Full Text] [PDF]  

Sherrye T. Glaser, S. John Gatley, and Andrew N. Gifford

Ex Vivo Imaging of Fatty Acid Amide Hydrolase Activity and Its Inhibition in the Mouse Brain
J Pharmacol Exp Ther 2006 316: 1088-1097. Published online November 8, 2005; 10.1124/jpet.105.094748 [Abstract] [Full Text] [PDF]  

Judy J. Watson, Mark S. Fahey, Edwin van den Worm, Ferdi Engels, Frans P. Nijkamp, Paul Stroemer, Steve McMahon, Shelley J. Allen, and David Dawbarn

TrkAd5: A Novel Therapeutic Agent for Treatment of Inflammatory Pain and Asthma
J Pharmacol Exp Ther 2006 316: 1122-1129. Published online November 11, 2005; 10.1124/jpet.105.095844 [Abstract] [Full Text] [PDF]  

Tomomi Oki, Ayako Toma-Okura, and Shizuo Yamada

Advantages for Transdermal over Oral Oxybutynin to Treat Overactive Bladder: Muscarinic Receptor Binding, Plasma Drug Concentration, and Salivary Secretion
J Pharmacol Exp Ther 2006 316: 1137-1145. Published online November 10, 2005; 10.1124/jpet.105.094508 [Abstract] [Full Text] [PDF]  

Karin M. Thelen, Katharina M. Rentsch, Ursula Gutteck, Maura Heverin, Maria Olin, Ulla Andersson, Arnold von Eckardstein, Ingemar Björkhem, and Dieter Lütjohann

Brain Cholesterol Synthesis in Mice Is Affected by High Dose of Simvastatin but Not of Pravastatin
J Pharmacol Exp Ther 2006 316: 1146-1152. Published online November 10, 2005; 10.1124/jpet.105.094136 [Abstract] [Full Text] [PDF]  

G. R. Dawson, K. A. Maubach, N. Collinson, M. Cobain, B. J. Everitt, A. M. MacLeod, H. I. Choudhury, L. M. McDonald, G. Pillai, W. Rycroft, A. J. Smith, F. Sternfeld, F. D. Tattersall, K. A. Wafford, D. S. Reynolds, G. R. Seabrook, and J. R. Atack

An Inverse Agonist Selective for 5 Subunit-Containing GABA_A Receptors Enhances Cognition
J Pharmacol Exp Ther 2006 316: 1335-1345. Published online December 2, 2005; 10.1124/jpet.105.092320 [Abstract] [Full Text] [PDF]  

Signe í Stórustovu and Bjarke Ebert

Pharmacological Characterization of Agonists at -Containing GABA_A Receptors: Functional Selectivity for Extrasynaptic Receptors Is Dependent on the Absence of ₂
J Pharmacol Exp Ther 2006 316: 1351-1359. Published online November 4, 2005; 10.1124/jpet.105.092403 [Abstract] [Full Text] [PDF]  

Cecilia M. Borghese, Signe í Stórustovu, Bjarke Ebert, Murray B. Herd, Delia Belelli, Jeremy J. Lambert, George Marshall, Keith A. Wafford, and R. Adron Harris

The Subunit of -Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol
J Pharmacol Exp Ther 2006 316: 1360-1368. Published online November 4, 2005; 10.1124/jpet.105.092452 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Jeffrey F. Waring, Michael J. Liguori, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Robert F. Stachlewitz, Colin North, Eric A. G. Blomme, and Robert A. Roth

Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils
J Pharmacol Exp Ther 2006 316: 1080-1087. Published online November 18, 2005; 10.1124/jpet.105.096347 [Abstract] [Full Text] [PDF] [Data supplement]   

Feng Xu, David A. Putt, Larry H. Matherly, and Lawrence H. Lash

Modulation of Expression of Rat Mitochondrial 2-Oxoglutarate Carrier in NRK-52E Cells Alters Mitochondrial Transport and Accumulation of Glutathione and Susceptibility to Chemically Induced Apoptosis
J Pharmacol Exp Ther 2006 316: 1175-1186. Published online November 15, 2005; 10.1124/jpet.105.094599 [Abstract] [Full Text] [PDF]  

Jie Yuan, George Hatzidimitriou, Pranav Suthar, Melanie Mueller, Una McCann, and George Ricaurte

Relationship between Temperature, Dopaminergic Neurotoxicity, and Plasma Drug Concentrations in Methamphetamine-Treated Squirrel Monkeys
J Pharmacol Exp Ther 2006 316: 1210-1218. Published online November 17, 2005; 10.1124/jpet.105.096503 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Kari T. Kivistö

Comments on "Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems"
J Pharmacol Exp Ther 2006 316: 1386. [Full Text] [PDF]  

Yvonne Y. Lau, Hideaki Okochi, Yong Huang, and Leslie Z. Benet

Response to Comments on "Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems"
J Pharmacol Exp Ther 2006 316: 1387. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.