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Other Issues:
December 2005; 315 (3)   [Index by Author]  [Cover Caption]
       PERSPECTIVES IN PHARMACOLOGY
       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
       BEHAVIORAL PHARMACOLOGY
       CARDIOVASCULAR
       CELLULAR AND MOLECULAR
       CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
       ENDOCRINE AND DIABETES
       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
       INFLAMMATION AND IMMUNOPHARMACOLOGY
       NEUROPHARMACOLOGY
       TOXICOLOGY
       LETTERS TO THE EDITOR
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PERSPECTIVES IN PHARMACOLOGY:

Amit Arora and Eric M. Scholar
Role of Tyrosine Kinase Inhibitors in Cancer Therapy
J Pharmacol Exp Ther 2005 315: 971-979. Published online July 7, 2005; 10.1124/jpet.105.084145 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Carolina I. Ghanem, María L. Ruiz, Silvina S. M. Villanueva, Marcelo G. Luquita, Viviana A. Catania, Brett Jones, Laura A. Bengochea, Mary Vore, and Aldo D. Mottino
Shift from Biliary to Urinary Elimination of Acetaminophen-Glucuronide in Acetaminophen-Pretreated Rats
J Pharmacol Exp Ther 2005 315: 987-995. Published online August 18, 2005; 10.1124/jpet.105.090613 [Abstract] [Full Text] [PDF]  

Chowdhury R. Ahsan, György Hajnóczky, Andrew B. Maksymowych, and Lance L. Simpson
Visualization of Binding and Transcytosis of Botulinum Toxin by Human Intestinal Epithelial Cells
J Pharmacol Exp Ther 2005 315: 1028-1035. Published online September 6, 2005; 10.1124/jpet.105.092213 [Abstract] [Full Text] [PDF]  

Tracy C. DeLozier, Soo-Chin Lee, Sherry J. Coulter, Boon Cher Goh, and Joyce A. Goldstein
Functional Characterization of Novel Allelic Variants of CYP2C9 Recently Discovered in Southeast Asians
J Pharmacol Exp Ther 2005 315: 1085-1090. Published online August 11, 2005; 10.1124/jpet.105.091181 [Abstract] [Full Text] [PDF]  

Hong Shen, Richard F. Keep, Yongjun Hu, and David E. Smith
PEPT2 (Slc15a2)-Mediated Unidirectional Transport of Cefadroxil from Cerebrospinal Fluid into Choroid Plexus
J Pharmacol Exp Ther 2005 315: 1101-1108. Published online August 17, 2005; 10.1124/jpet.105.090654 [Abstract] [Full Text] [PDF]  

Cornelia M. Smith, Richard A. Graham, Wojciech L. Krol, Ivin S. Silver, Masahiko Negishi, Hongbing Wang, and Edward L. Lecluyse
Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells
J Pharmacol Exp Ther 2005 315: 1256-1264. Published online August 31, 2005; 10.1124/jpet.105.090795 [Abstract] [Full Text] [PDF]  

David L. Bourdet, John B. Pritchard, and Dhiren R. Thakker
Differential Substrate and Inhibitory Activities of Ranitidine and Famotidine toward Human Organic Cation Transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
J Pharmacol Exp Ther 2005 315: 1288-1297. Published online September 1, 2005; 10.1124/jpet.105.091223 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Pastor R. Couceyro, Charity Evans, Audra McKinzie, Darrion Mitchell, Matt Dube, Leila Hagshenas, Francis J. White, Jim Douglass, William G. Richards, and Anthony W. Bannon
Cocaine- and Amphetamine-Regulated Transcript (CART) Peptides Modulate the Locomotor and Motivational Properties of Psychostimulants
J Pharmacol Exp Ther 2005 315: 1091-1100. Published online August 11, 2005; 10.1124/jpet.105.091678 [Abstract] [Full Text] [PDF]  

Ruggero Galici, Nicholas G. Echemendia, Alice L. Rodriguez, and P. Jeffrey Conn
A Selective Allosteric Potentiator of Metabotropic Glutamate (mGlu) 2 Receptors Has Effects Similar to an Orthosteric mGlu2/3 Receptor Agonist in Mouse Models Predictive of Antipsychotic Activity
J Pharmacol Exp Ther 2005 315: 1181-1187. Published online August 25, 2005; 10.1124/jpet.105.091074 [Abstract] [Full Text] [PDF]  

Sandra D. Comer, Maria A. Sullivan, and Ellen A. Walker
Comparison of Intravenous Buprenorphine and Methadone Self-Administration by Recently Detoxified Heroin-Dependent Individuals
J Pharmacol Exp Ther 2005 315: 1320-1330. Published online September 6, 2005; 10.1124/jpet.105.090423 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Pratik Parikh, Lazaros A. Nikolaidis, Carol Stolarski, You-Tang Shen, and Richard P. Shannon
Chronic Exposure to Cocaine Binging Predisposes to an Accelerated Course of Dilated Cardiomyopathy in Conscious Dogs following Rapid Ventricular Pacing
J Pharmacol Exp Ther 2005 315: 1013-1019. Published online August 25, 2005; 10.1124/jpet.105.088161 [Abstract] [Full Text] [PDF]  

Douglas G. Johns, Zhaohui Ao, Marianne Eybye, Alan Olzinski, Melissa Costell, Susan Gruver, Stephen A. Smith, Stephen A. Douglas, and Colin H. Macphee
Rosiglitazone Protects against Ischemia/Reperfusion-Induced Leukocyte Adhesion in the Zucker Diabetic Fatty Rat
J Pharmacol Exp Ther 2005 315: 1020-1027. Published online August 25, 2005; 10.1124/jpet.105.090993 [Abstract] [Full Text] [PDF]  

E. Dabbs Loomis, Jennifer C. Sullivan, David A. Osmond, David M. Pollock, and Jennifer S. Pollock
Endothelin Mediates Superoxide Production and Vasoconstriction through Activation of NADPH Oxidase and Uncoupled Nitric-Oxide Synthase in the Rat Aorta
J Pharmacol Exp Ther 2005 315: 1058-1064. Published online September 6, 2005; 10.1124/jpet.105.091728 [Abstract] [Full Text] [PDF]  

Asad Zeidan, Daniel M. Purdham, Venkatesh Rajapurohitam, Sabzali Javadov, Subrata Chakrabarti, and Morris Karmazyn
Leptin Induces Vascular Smooth Muscle Cell Hypertrophy through Angiotensin II- and Endothelin-1-Dependent Mechanisms and Mediates Stretch-Induced Hypertrophy
J Pharmacol Exp Ther 2005 315: 1075-1084. Published online September 6, 2005; 10.1124/jpet.105.091561 [Abstract] [Full Text] [PDF]  

Soochan Bae and Lubo Zhang
Gender Differences in Cardioprotection against Ischemia/Reperfusion Injury in Adult Rat Hearts: Focus on Akt and Protein Kinase C Signaling
J Pharmacol Exp Ther 2005 315: 1125-1135. Published online August 11, 2005; 10.1124/jpet.105.090803 [Abstract] [Full Text] [PDF]  

Zhu-Shan Zhang, Heng-Jie Cheng, Katsuya Onishi, Nobuyuki Ohte, Thomas Wannenburg, and Che-Ping Cheng
Enhanced Inhibition of L-type Ca2+ Current by {beta}3-Adrenergic Stimulation in Failing Rat Heart
J Pharmacol Exp Ther 2005 315: 1203-1211. Published online August 31, 2005; 10.1124/jpet.105.089672 [Abstract] [Full Text] [PDF]  

Jean-Pierre Dollé, Amir Rezvan, Fred D. Allen, Philip Lazarovici, and Peter I. Lelkes
Nerve Growth Factor-Induced Migration of Endothelial Cells
J Pharmacol Exp Ther 2005 315: 1220-1227. Published online August 25, 2005; 10.1124/jpet.105.093252 [Abstract] [Full Text] [PDF]  

Anthony C. Sulpizio, Mark A. Pullen, Richard M. Edwards, James B. Louttit, Rob West, and David P. Brooks
Mechanism of Vasopeptidase Inhibitor-Induced Plasma Extravasation: Comparison of Omapatrilat and the Novel Neutral Endopeptidase 24.11/Angiotensin-Converting Enzyme Inhibitor GW796406
J Pharmacol Exp Ther 2005 315: 1306-1313. Published online September 6, 2005; 10.1124/jpet.105.084749 [Abstract] [Full Text] [PDF]  

Teresa Corazzi, Mario Leone, Raffaella Maucci, Lanfranco Corazzi, and Paolo Gresele
Direct and Irreversible Inhibition of Cyclooxygenase-1 by Nitroaspirin (NCX 4016)
J Pharmacol Exp Ther 2005 315: 1331-1337. Published online September 6, 2005; 10.1124/jpet.105.089896 [Abstract] [Full Text] [PDF]  

Gary L. Stump, Audrey A. Wallace, Christopher P. Regan, and Joseph J. Lynch, Jr.
In Vivo Antiarrhythmic and Cardiac Electrophysiologic Effects of a Novel Diphenylphosphine Oxide IKur Blocker (2-Isopropyl-5-methylcyclohexyl) Diphenylphosphine Oxide
J Pharmacol Exp Ther 2005 315: 1362-1367. Published online September 12, 2005; 10.1124/jpet.105.092197 [Abstract] [Full Text] [PDF]  

Maura Floreani, Guglielmina Froldi, Luigi Quintieri, Katia Varani, Pier Andrea Borea, Maria Teresa Dorigo, and Paola Dorigo
In Vitro Evidence That Carteolol Is a Nonconventional Partial Agonist of Guinea Pig Cardiac {beta}1-Adrenoceptors: A Comparison with Xamoterol
J Pharmacol Exp Ther 2005 315: 1386-1395. Published online September 13, 2005; 10.1124/jpet.105.088963 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Narasimharao Bhagavathula, Kamalakar C. Nerusu, Mahendranath Reddy, Charles N. Ellis, Amar Chittiboyina, Mitchell Avery, Harrihar A. Pershadsingh, Theodore W. Kurtz, and James Varani
BP-1107 [{2-[4-(2,4-Dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: A Novel Synthetic Thiazolidinedione That Inhibits Epidermal Hyperplasia in Psoriatic Skin-Severe-Combined Immunodeficient Mouse Transplants after Topical Application
J Pharmacol Exp Ther 2005 315: 996-1004. Published online August 18, 2005; 10.1124/jpet.105.091066 [Abstract] [Full Text] [PDF]  

Ulrike Seay, Daniel Sedding, Stefanie Krick, Matthias Hecker, Werner Seeger, and Oliver Eickelberg
Transforming Growth Factor-{beta}-Dependent Growth Inhibition in Primary Vascular Smooth Muscle Cells Is p38-Dependent
J Pharmacol Exp Ther 2005 315: 1005-1012. Published online August 24, 2005; 10.1124/jpet.105.091249 [Abstract] [Full Text] [PDF]  

Ortrud Uckermann, Franziska Kutzera, Antje Wolf, Thomas Pannicke, Andreas Reichenbach, Peter Wiedemann, Sebastian Wolf, and Andreas Bringmann
The Glucocorticoid Triamcinolone Acetonide Inhibits Osmotic Swelling of Retinal Glial Cells via Stimulation of Endogenous Adenosine Signaling
J Pharmacol Exp Ther 2005 315: 1036-1045. Published online September 6, 2005; 10.1124/jpet.105.092353 [Abstract] [Full Text] [PDF]  

Marina Pierdominici, Anna Maria Giammarioli, Lucrezia Gambardella, Marco De Felice, Isabella Quinti, Metello Iacobini, Maurizio Carbonari, Walter Malorni, and Antonello Giovannetti
Pyrimethamine (2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine) Induces Apoptosis of Freshly Isolated Human T Lymphocytes, Bypassing CD95/Fas Molecule but Involving Its Intrinsic Pathway
J Pharmacol Exp Ther 2005 315: 1046-1057. Published online September 12, 2005; 10.1124/jpet.105.086736 [Abstract] [Full Text] [PDF]  

Moshe Finel, Xin Li, Dione Gardner-Stephen, Stacie Bratton, Peter I. Mackenzie, and Anna Radominska-Pandya
Human UDP-Glucuronosyltransferase 1A5: Identification, Expression, and Activity
J Pharmacol Exp Ther 2005 315: 1143-1149. Published online August 24, 2005; 10.1124/jpet.105.091900 [Abstract] [Full Text] [PDF]  

Jody M. Tucker, Zhanna Lipatova, Vladimir Beljanski, Danyelle M. Townsend, and Kenneth D. Tew
Evaluation of Lipophilins as Determinants of Tumor Cell Response to Estramustine
J Pharmacol Exp Ther 2005 315: 1158-1162. Published online August 24, 2005; 10.1124/jpet.105.090860 [Abstract] [Full Text] [PDF]  

Hyun Jeong Kwak, Jin Sook Song, Jun Young Heo, Sung Don Yang, Ji-Youn Nam, and Hyae Gyeong Cheon
Roflumilast Inhibits Lipopolysaccharide-Induced Inflammatory Mediators via Suppression of Nuclear Factor-{kappa}B, p38 Mitogen-Activated Protein Kinase, and c-Jun NH2-Terminal Kinase Activation
J Pharmacol Exp Ther 2005 315: 1188-1195. Published online August 26, 2005; 10.1124/jpet.105.092056 [Abstract] [Full Text] [PDF]  

Ning Qin, Sui-Po Zhang, Tasha L. Reitz, Jay M. Mei, and Christopher M. Flores
Cloning, Expression, and Functional Characterization of Human Cyclooxygenase-1 Splicing Variants: Evidence for Intron 1 Retention
J Pharmacol Exp Ther 2005 315: 1298-1305. Published online September 1, 2005; 10.1124/jpet.105.090944 [Abstract] [Full Text] [PDF]  

Rainer K. Reinscheid, Yan-Ling Xu, Naoe Okamura, Joanne Zeng, Shinjae Chung, Rama Pai, Zhiwei Wang, and Olivier Civelli
Pharmacological Characterization of Human and Murine Neuropeptide S Receptor Variants
J Pharmacol Exp Ther 2005 315: 1338-1345. Published online September 6, 2005; 10.1124/jpet.105.093427 [Abstract] [Full Text] [PDF]  

Masaaki Sato, Dana S. Hutchinson, Tore Bengtsson, Anders Floren, Ülo Langel, Takahiro Horinouchi, Bronwyn A. Evans, and Roger J. Summers
Functional Domains of the Mouse {beta}3-Adrenoceptor Associated with Differential G Protein Coupling
J Pharmacol Exp Ther 2005 315: 1354-1361. Published online September 6, 2005; 10.1124/jpet.105.091736 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Ryan J. Hansen, Ramamoorthy Nagasubramanian, Shannon M. Delaney, Mathew M. Cherian, Shang Lin, Scott C. Kogan, and M. Eileen Dolan
Role of O6-Alkylguanine-DNA Alkyltransferase in Protecting against 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-Induced Long-Term Toxicities
J Pharmacol Exp Ther 2005 315: 1247-1255. Published online August 26, 2005; 10.1124/jpet.105.083501 [Abstract] [Full Text] [PDF]  

C. Gaiddon, P. Jeannequin, P. Bischoff, M. Pfeffer, C. Sirlin, and J. P. Loeffler
Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms
J Pharmacol Exp Ther 2005 315: 1403-1411. Published online September 16, 2005; 10.1124/jpet.105.089342 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Thomas H. Claus, Derek B. Lowe, Yin Liang, Arthur I. Salhanick, Christine Keiper Lubeski, Ling Yang, Lynn Lemoine, Jian Zhu, and Kevin B. Clairmont
Specific Inhibition of Hormone-Sensitive Lipase Improves Lipid Profile while Reducing Plasma Glucose
J Pharmacol Exp Ther 2005 315: 1396-1402. Published online September 14, 2005; 10.1124/jpet.105.086926 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

P. B. Hansen, S. Hashimoto, M. Oppermann, Y. Huang, J. P. Briggs, and J. Schnermann
Vasoconstrictor and Vasodilator Effects of Adenosine in the Mouse Kidney due to Preferential Activation of A1 or A2 Adenosine Receptors
J Pharmacol Exp Ther 2005 315: 1150-1157. Published online August 24, 2005; 10.1124/jpet.105.091017 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Marie Eve Moreau, Pascal Dubreuil, Giuseppe Molinaro, Miguel Chagnon, Werner Müller-Esterl, Yves Lepage, François Marceau, and Albert Adam
Expression of Metallopeptidases and Kinin Receptors in Swine Oropharyngeal Tissues: Effects of Angiotensin I-Converting Enzyme Inhibition and Inflammation
J Pharmacol Exp Ther 2005 315: 1065-1074. Published online September 15, 2005; 10.1124/jpet.105.088005 [Abstract] [Full Text] [PDF]  

Debora Porath, Christoph Riegger, Juergen Drewe, and Joseph Schwager
Epigallocatechin-3-gallate Impairs Chemokine Production in Human Colon Epithelial Cell Lines
J Pharmacol Exp Ther 2005 315: 1172-1180. Published online August 25, 2005; 10.1124/jpet.105.090167 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Timothy J. Shafer, Philip J. Bushnell, Vernon A. Benignus, and John J. Woodward
Perturbation of Voltage-Sensitive Ca2+ Channel Function by Volatile Organic Solvents
J Pharmacol Exp Ther 2005 315: 1109-1118. Published online August 18, 2005; 10.1124/jpet.105.090027 [Abstract] [Full Text] [PDF]  

Miyako Yoshida, Satoru Koyanagi, Ayaka Matsuo, Toshihiro Fujioka, Hideto To, Shun Higuchi, and Shigehiro Ohdo
Glucocorticoid Hormone Regulates the Circadian Coordination of µ-Opioid Receptor Expression in Mouse Brainstem
J Pharmacol Exp Ther 2005 315: 1119-1124. Published online August 18, 2005; 10.1124/jpet.105.091488 [Abstract] [Full Text] [PDF] Data Supplement  

Koichi Nakae, Kiyoko Saito, Takashi Iino, Noriyuki Yamamoto, Mayo Wakabayashi, Satoru Yoshikawa, Satoshi Matsushima, Hiroshi Miyashita, Hiromi Sugimoto, Atushi Kiba, and Jung Gupta
A Prostacyclin Receptor Antagonist Inhibits the Sensitized Release of Substance P from Rat Sensory Neurons
J Pharmacol Exp Ther 2005 315: 1136-1142. Published online August 18, 2005; 10.1124/jpet.105.091967 [Abstract] [Full Text] [PDF]  

Jacob C. Ong, Suzanne A. Brody, Charles H. Large, and Mark A. Geyer
An Investigation of the Efficacy of Mood Stabilizers in Rodent Models of Prepulse Inhibition
J Pharmacol Exp Ther 2005 315: 1163-1171. Published online August 25, 2005; 10.1124/jpet.105.090845 [Abstract] [Full Text] [PDF]  

Sanjaya Kuruppu, Shane Reeve, Yajnavalka Banerjee, R. Manjunatha Kini, A. Ian Smith, and Wayne C. Hodgson
Isolation and Pharmacological Characterization of Cannitoxin, a Presynaptic Neurotoxin from the Venom of the Papuan Taipan (Oxyuranus scutellatus canni)
J Pharmacol Exp Ther 2005 315: 1196-1202. Published online August 31, 2005; 10.1124/jpet.105.093641 [Abstract] [Full Text] [PDF]  

Yongqin Zhang, Alice L. Rodriguez, and P. Jeffrey Conn
Allosteric Potentiators of Metabotropic Glutamate Receptor Subtype 5 Have Differential Effects on Different Signaling Pathways in Cortical Astrocytes
J Pharmacol Exp Ther 2005 315: 1212-1219. Published online August 31, 2005; 10.1124/jpet.105.090308 [Abstract] [Full Text] [PDF]  

Vaneeta Verma, Amandeep Mann, Willard Costain, Giuseppe Pontoriero, Jessica M. Castellano, Kevin Skoblenick, Suresh K. Gupta, Zdenek Pristupa, Hyman B. Niznik, Rodney L. Johnson, Venugopalan D. Nair, and Ram K. Mishra
Modulation of Agonist Binding to Human Dopamine Receptor Subtypes by L-Prolyl-L-leucyl-glycinamide and a Peptidomimetic Analog
J Pharmacol Exp Ther 2005 315: 1228-1236. Published online August 26, 2005; 10.1124/jpet.105.091256 [Abstract] [Full Text] [PDF]  

Pál Kocsis, Sándor Farkas, László Fodor, Norbert Bielik, Márta Thán, Sándor Kolok, Anikó Gere, Mónika Csejtei, and István Tarnawa
Tolperisone-Type Drugs Inhibit Spinal Reflexes via Blockade of Voltage-Gated Sodium and Calcium Channels
J Pharmacol Exp Ther 2005 315: 1237-1246. Published online August 26, 2005; 10.1124/jpet.105.089805 [Abstract] [Full Text] [PDF]  

Kurt Rasmussen, Mark J. Benvenga, Frank P. Bymaster, David O. Calligaro, Ilene R. Cohen, Julie F. Falcone, Susan K. Hemrick-Luecke, Fionna M. Martin, Nicholas A. Moore, Laura K. Nisenbaum, John M. Schaus, Sarah J. Sundquist, David E. Tupper, Todd R. Wiernicki, and David L. Nelson
Preclinical Pharmacology of FMPD [6-Fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: A Potential Novel Antipsychotic with Lower Histamine H1 Receptor Affinity Than Olanzapine
J Pharmacol Exp Ther 2005 315: 1265-1277. Published online September 1, 2005; 10.1124/jpet.105.089326 [Abstract] [Full Text] [PDF]  

E. S. Burstein, J. Ma, S. Wong, Y. Gao, E. Pham, A. E. Knapp, N. R. Nash, R. Olsson, R. E. Davis, U. Hacksell, D. M. Weiner, and M. R. Brann
Intrinsic Efficacy of Antipsychotics at Human D2, D3, and D4 Dopamine Receptors: Identification of the Clozapine Metabolite N-Desmethylclozapine as a D2/D3 Partial Agonist
J Pharmacol Exp Ther 2005 315: 1278-1287. Published online August 31, 2005; 10.1124/jpet.105.092155 [Abstract] [Full Text] [PDF]  

Esperanza Arias, Sonia Gallego-Sandín, Mercedes Villarroya, Antonio G. García, and Manuela G. López
Unequal Neuroprotection Afforded by the Acetylcholinesterase Inhibitors Galantamine, Donepezil, and Rivastigmine in SH-SY5Y Neuroblastoma Cells: Role of Nicotinic Receptors
J Pharmacol Exp Ther 2005 315: 1346-1353. Published online September 6, 2005; 10.1124/jpet.105.090365 [Abstract] [Full Text] [PDF]  

Evangelia Morou and Zafiroula Georgoussi
Expression of the Third Intracellular Loop of the {delta}-Opioid Receptor Inhibits Signaling by Opioid Receptors and Other G Protein-Coupled Receptors
J Pharmacol Exp Ther 2005 315: 1368-1379. Published online September 13, 2005; 10.1124/jpet.105.089946 [Abstract] [Full Text] [PDF]  

P. R. Holland, S. Akerman, and P. J. Goadsby
Orexin 1 Receptor Activation Attenuates Neurogenic Dural Vasodilation in an Animal Model of Trigeminovascular Nociception
J Pharmacol Exp Ther 2005 315: 1380-1385. Published online September 13, 2005; 10.1124/jpet.105.090951 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Zachary S. Bowman, David J. Jollow, and David C. McMillan
Primaquine-Induced Hemolytic Anemia: Role of Splenic Macrophages in the Fate of 5-Hydroxyprimaquine-Treated Rat Erythrocytes
J Pharmacol Exp Ther 2005 315: 980-986. Published online August 12, 2005; 10.1124/jpet.105.090407 [Abstract] [Full Text] [PDF]  

Kevyn E. Merten, Wenke Feng, Li Zhang, William Pierce, Jian Cai, Jon B. Klein, and Y. James Kang
Modulation of Cytochrome c Oxidase-Va Is Possibly Involved in Metallothionein Protection from Doxorubicin Cardiotoxicity
J Pharmacol Exp Ther 2005 315: 1314-1319. Published online September 6, 2005; 10.1124/jpet.105.089763 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Daniel L. Simmons, N. V. Chandrasekharan, Dai Hu, K. Lamar Roos, and Joshua Tomsik
Comments on "Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties"
J Pharmacol Exp Ther 2005 315: 1412-1414. [Full Text] [PDF]  

Bela Kis, James A. Snipes, and David W. Busija
Response to Comments on "Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties"
J Pharmacol Exp Ther 2005 315: 1415-1416. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the Cover:  Acute application of glutamate or high-K+ evokes morphological alterations in wholemount guinea pig retinas that are not inhibited by triamcinolone. See the article by Uckermann et al. on page 1036 of this issue.



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