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Other Issues:
October 2005; 315 (1)   [Index by Author]  [Cover Caption]
       PERSPECTIVES IN PHARMACOLOGY
       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
       BEHAVIORAL PHARMACOLOGY
       CARDIOVASCULAR
       CELLULAR AND MOLECULAR
       CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
       ENDOCRINE AND DIABETES
       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
       INFLAMMATION AND IMMUNOPHARMACOLOGY
       NEUROPHARMACOLOGY
       TOXICOLOGY
       ERRATA
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PERSPECTIVES IN PHARMACOLOGY:

Bela Kis, James A. Snipes, and David W. Busija
Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties
J Pharmacol Exp Ther 2005 315: 1-7. Published online May 6, 2005; 10.1124/jpet.105.085431 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Angelo Mancinelli, Allan M. Evans, Roger L. Nation, and Antonio Longo
Uptake of L-Carnitine and Its Short-Chain Ester Propionyl-L-carnitine in the Isolated Perfused Rat Liver
J Pharmacol Exp Ther 2005 315: 118-124. Published online June 10, 2005; 10.1124/jpet.105.087890 [Abstract] [Full Text] [PDF]  

Simon Lowes, Destiny Sykes, Christopher M. Breen, Leigh J. Ragone, and David S. Miller
Multiple Components of 2,4-Dichlorophenoxyacetic Acid Uptake by Rat Choroid Plexus
J Pharmacol Exp Ther 2005 315: 136-143. Published online June 15, 2005; 10.1124/jpet.105.087056 [Abstract] [Full Text] [PDF]  

Haiqing Dai, Ying Chen, and William F. Elmquist
Distribution of the Novel Antifolate Pemetrexed to the Brain
J Pharmacol Exp Ther 2005 315: 222-229. Published online June 29, 2005; 10.1124/jpet.105.090043 [Abstract] [Full Text] [PDF]  

Scott M. Ocheltree, Hong Shen, Yongjun Hu, Richard F. Keep, and David E. Smith
Role and Relevance of Peptide Transporter 2 (PEPT2) in the Kidney and Choroid Plexus: In Vivo Studies with Glycylsarcosine in Wild-Type and PEPT2 Knockout Mice
J Pharmacol Exp Ther 2005 315: 240-247. Published online June 29, 2005; 10.1124/jpet.105.089359 [Abstract] [Full Text] [PDF]  

Krzysztof J. Reszka, Laura H. Britigan, and Bradley E. Britigan
Oxidation of Anthracyclines by Peroxidase Metabolites of Salicylic Acid
J Pharmacol Exp Ther 2005 315: 283-290. Published online June 28, 2005; 10.1124/jpet.105.089417 [Abstract] [Full Text] [PDF]  

Harunobu Tahara, Hiroyuki Kusuhara, Hitoshi Endou, Hermann Koepsell, Tomoki Imaoka, Eiichi Fuse, and Yuichi Sugiyama
A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters
J Pharmacol Exp Ther 2005 315: 337-345. Published online July 8, 2005; 10.1124/jpet.105.088104 [Abstract] [Full Text] [PDF]  

K. Bach-Ngohou, K. Ouguerram, R. Frénais, P. Maugère, B. Ripolles-Piquer, Y. Zaïr, M. Krempf, and J. M. Bard
Influence of Atorvastatin on Apolipoprotein E and AI Kinetics in Patients with Type 2 Diabetes
J Pharmacol Exp Ther 2005 315: 363-369. Published online July 13, 2005; 10.1124/jpet.105.085522 [Abstract] [Full Text] [PDF]  

Lichuan Liu, Ernie Mak, Rommel G. Tirona, Eugene Tan, Phyllis M. Novikoff, Pijun Wang, Allan W. Wolkoff, and K. Sandy Pang
Vascular Binding, Blood Flow, Transporter, and Enzyme Interactions on the Processing of Digoxin in Rat Liver
J Pharmacol Exp Ther 2005 315: 433-448. Published online June 30, 2005; 10.1124/jpet.105.088039 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Becky Kinkead, Paul R. Dobner, Vasili Egnatashvili, Tiesha Murray, Nancy Deitemeyer, and Charles B. Nemeroff
Neurotensin-Deficient Mice Have Deficits in Prepulse Inhibition: Restoration by Clozapine but Not Haloperidol, Olanzapine, or Quetiapine
J Pharmacol Exp Ther 2005 315: 256-264. Published online June 29, 2005; 10.1124/jpet.105.087437 [Abstract] [Full Text] [PDF]  

Rajeev I. Desai, Theresa A. Kopajtic, Dawn French, Amy H. Newman, and Jonathan L. Katz
Relationship between in Vivo Occupancy at the Dopamine Transporter and Behavioral Effects of Cocaine, GBR 12909 [1-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and Benztropine Analogs
J Pharmacol Exp Ther 2005 315: 397-404. Published online July 13, 2005; 10.1124/jpet.105.091231 [Abstract] [Full Text] [PDF]  

Emily M. Jutkiewicz, Sarah T. Kaminsky, Kenner C. Rice, John R. Traynor, and James H. Woods
Differential Behavioral Tolerance to the {delta}-Opioid Agonist SNC80 ([(+)-4-[({alpha}R)-{alpha}-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley Rats
J Pharmacol Exp Ther 2005 315: 414-422. Published online July 13, 2005; 10.1124/jpet.105.088831 [Abstract] [Full Text] [PDF]  

Richard M. Allen, Regina M. Carelli, Linda A. Dykstra, Therese L. Suchey, and Carson V. Everett
Effects of the Competitive N-Methyl-D-aspartate Receptor Antagonist, LY235959 [(-)-6-Phosphonomethyl-deca-hydroisoquinoline-3-carboxylic Acid], on Responding for Cocaine under Both Fixed and Progressive Ratio Schedules of Reinforcement
J Pharmacol Exp Ther 2005 315: 449-457. Published online July 15, 2005; 10.1124/jpet.105.086355 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

C. Ian Spencer and James S. K. Sham
Mechanisms Underlying the Effects of the Pyrethroid Tefluthrin on Action Potential Duration in Isolated Rat Ventricular Myocytes
J Pharmacol Exp Ther 2005 315: 16-23. Published online June 24, 2005; 10.1124/jpet.105.084822 [Abstract] [Full Text] [PDF]  

Bernardo Rodríguez-Iturbe, Atilio Ferrebuz, Valentina Vanegas, Yasmir Quiroz, Sergio Mezzano, and Nosratola D. Vaziri
Early and Sustained Inhibition of Nuclear Factor-{kappa}B Prevents Hypertension in Spontaneously Hypertensive Rats
J Pharmacol Exp Ther 2005 315: 51-57. Published online June 10, 2005; 10.1124/jpet.105.088062 [Abstract] [Full Text] [PDF]  

Anita Pálfi, Ambrus Tóth, Gyozo Kulcsár, Katalin Hantó, Péter Deres, Éva Bartha, Róbert Halmosi, Eszter Szabados, László Czopf, Tamás Kálai, Kálmán Hideg, Balázs Sümegi, and Kálmán Tóth
The Role of Akt and Mitogen-Activated Protein Kinase Systems in the Protective Effect of Poly(ADP-Ribose) Polymerase Inhibition in Langendorff Perfused and in Isoproterenol-Damaged Rat Hearts
J Pharmacol Exp Ther 2005 315: 273-282. Published online June 10, 2005; 10.1124/jpet.105.088336 [Abstract] [Full Text] [PDF]  

Jan Kyselovic, Peter Martinka, Zuzana Batova, Andrea Gazova, and Theophile Godfraind
Calcium Channel Blocker Inhibits Western-Type Diet-Evoked Atherosclerosis Development in ApoE-Deficient Mice
J Pharmacol Exp Ther 2005 315: 320-328. Published online July 14, 2005; 10.1124/jpet.105.089847 [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR AND MOLECULAR:

Alexandre Mezentsev, Vladimir Mastyugin, Francesca Seta, Silvia Ashkar, Rowena Kemp, D. Sudarshan Reddy, John R. Falck, Michael W. Dunn, and Michal Laniado-Schwartzman
Transfection of Cytochrome P4504B1 into the Cornea Increases Angiogenic Activity of the Limbal Vessels
J Pharmacol Exp Ther 2005 315: 42-50. Published online July 11, 2005; 10.1124/jpet.105.088211 [Abstract] [Full Text] [PDF]  

Ariel R. Ase, Ramin Raouf, Danny Bélanger, Édith Hamel, and Philippe Séguéla
Potentiation of P2X1 ATP-Gated Currents by 5-Hydroxytryptamine 2A Receptors Involves Diacylglycerol-Dependent Kinases and Intracellular Calcium
J Pharmacol Exp Ther 2005 315: 144-154. Published online June 15, 2005; 10.1124/jpet.105.089045 [Abstract] [Full Text] [PDF]  

Cleber E. Teixeira, Zhekang Ying, and R. Clinton Webb
Proerectile Effects of the Rho-Kinase Inhibitor (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the Rat Penis
J Pharmacol Exp Ther 2005 315: 155-162. Published online June 23, 2005; 10.1124/jpet.105.086041 [Abstract] [Full Text] [PDF]  

Mohamed A. Abdelmegeed, Nicholas J. Carruthers, Kimberley J. Woodcroft, Sang K. Kim, and Raymond F. Novak
Acetoacetate Induces CYP2E1 Protein and Suppresses CYP2E1 mRNA in Primary Cultured Rat Hepatocytes
J Pharmacol Exp Ther 2005 315: 203-213. Published online June 24, 2005; 10.1124/jpet.105.084608 [Abstract] [Full Text] [PDF]  

Heng Xu, Xiaoying Wang, Darin Zimmerman, Emily S. Boja, Jiabei Wang, Edward J. Bilsky, and Richard B. Rothman
Chronic Morphine Up-Regulates G{alpha}12 and Cytoskeletal Proteins in Chinese Hamster Ovary Cells Expressing the Cloned µ Opioid Receptor
J Pharmacol Exp Ther 2005 315: 248-255. Published online June 29, 2005; 10.1124/jpet.105.089367 [Abstract] [Full Text] [PDF]  

Marianne K. O. Grant and Esam E. El-Fakahany
Persistent Binding and Functional Antagonism by Xanomeline at the Muscarinic M5 Receptor
J Pharmacol Exp Ther 2005 315: 313-319. Published online July 7, 2005; 10.1124/jpet.105.090134 [Abstract] [Full Text] [PDF]  

Christian Feißt, Lutz Franke, Giovanni Appendino, and Oliver Werz
Identification of Molecular Targets of the Oligomeric Nonprenylated Acylphloroglucinols from Myrtus communis and Their Implication as Anti-Inflammatory Compounds
J Pharmacol Exp Ther 2005 315: 389-396. Published online July 13, 2005; 10.1124/jpet.105.090720 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Gina E. Avila, Xi Zheng, Xiao Xing Cui, Amanda D. Ryan, Annette Hansson, Junghan Suh, Arnold B. Rabson, Richard L. Chang, Weichung Joe Shih, Yong Lin, Pamela Crowell, Yao Ping Lu, You Rong Lou, and Allan H. Conney
Inhibitory Effects of 12-O-Tetradecanoylphorbol-13-acetate Alone or in Combination with All-trans Retinoic Acid on the Growth of Cultured Human Pancreas Cancer Cells and Pancreas Tumor Xenografts in Immunodeficient Mice
J Pharmacol Exp Ther 2005 315: 170-187. Published online June 23, 2005; 10.1124/jpet.105.087585 [Abstract] [Full Text] [PDF]  

Jordi Martínez, Antonio Gutiérrez, Jesús Casas, Victoria Lladó, Alicia López-Bellan, Joan Besalduch, Ana Dopazo, and Pablo V. Escribá
The Repression of E2F-1 Is Critical for the Activity of Minerval against Cancer
J Pharmacol Exp Ther 2005 315: 466-474. Published online July 18, 2005; 10.1124/jpet.105.088716 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND DIABETES:

Juhyun Kim, Di Wu, Dong Jin Hwang, Duane D. Miller, and James T. Dalton
The Para Substituent of S-3-(Phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides Is a Major Structural Determinant of in Vivo Disposition and Activity of Selective Androgen Receptor Modulators
J Pharmacol Exp Ther 2005 315: 230-239. Published online June 29, 2005; 10.1124/jpet.105.088344 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

David L. Carbone, Jonathan A. Doorn, Zachary Kiebler, Brian R. Ickes, and Dennis R. Petersen
Modification of Heat Shock Protein 90 by 4-Hydroxynonenal in a Rat Model of Chronic Alcoholic Liver Disease
J Pharmacol Exp Ther 2005 315: 8-15. Published online June 10, 2005; 10.1124/jpet.105.088088 [Abstract] [Full Text] [PDF]  

Maria J. Monte, Maria R. Ballestero, Oscar Briz, Maria J. Perez, and Jose J. G. Marin
Proapoptotic Effect on Normal and Tumor Intestinal Cells of Cytostatic Drugs with Enterohepatic Organotropism
J Pharmacol Exp Ther 2005 315: 24-35. Published online June 28, 2005; 10.1124/jpet.105.086165 [Abstract] [Full Text] [PDF]  

Stefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, Barbara Renga, Andrea Mencarelli, Luisa Riccardi, Antonio Morelli, Mark Pruzanski, and Roberto Pellicciari
Cross-Talk between Farnesoid-X-Receptor (FXR) and Peroxisome Proliferator-Activated Receptor {gamma} Contributes to the Antifibrotic Activity of FXR Ligands in Rodent Models of Liver Cirrhosis
J Pharmacol Exp Ther 2005 315: 58-68. Published online June 24, 2005; 10.1124/jpet.105.085597 [Abstract] [Full Text] [PDF]  

P. C. M. Obiefuna, V. K. Batra, A. Nadeem, P. Borron, C. N. Wilson, and S. Jamal Mustafa
A Novel A1 Adenosine Receptor Antagonist, L-97-1 [3-[2-(4-Aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma
J Pharmacol Exp Ther 2005 315: 329-336. Published online July 14, 2005; 10.1124/jpet.105.088179 [Abstract] [Full Text] [PDF]  

Hisato Igarashi, Tetsuhide Ito, Samuel A. Mantey, Tapas K. Pradhan, Wei Hou, David H. Coy, and Robert T. Jensen
Development of Simplified Vasoactive Intestinal Peptide Analogs with Receptor Selectivity and Stability for Human Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase-Activating Polypeptide Receptors
J Pharmacol Exp Ther 2005 315: 370-381. Published online June 30, 2005; 10.1124/jpet.105.088823 [Abstract] [Full Text] [PDF]  

Eitaro Aihara, Masamune Hayashi, Yoko Sasaki, Atsushi Kobata, and Koji Takeuchi
Mechanisms Underlying Capsaicin-Stimulated Secretion in the Stomach: Comparison with Mucosal Acidification
J Pharmacol Exp Ther 2005 315: 423-432. Published online June 28, 2005; 10.1124/jpet.105.087619 [Abstract] [Full Text] [PDF]  

Anna-Karin Larsson, Magnus Bäck, Josephine Hjoberg, and Sven-Erik Dahlén
Inhibition of Nitric-Oxide Synthase Enhances Antigen-Induced Contractions and Increases Release of Cysteinyl-Leukotrienes in Guinea Pig Lung Parenchyma: Nitric Oxide as a Protective Factor
J Pharmacol Exp Ther 2005 315: 458-465. Published online July 15, 2005; 10.1124/jpet.105.086694 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Robert F. Stachlewitz, Michelle A. Hart, Brian Bettencourt, Tegest Kebede, Annette Schwartz, Sheldon E. Ratnofsky, David J. Calderwood, Wendy O. Waegell, and Gavin C. Hirst
A-770041, a Novel and Selective Small-Molecule Inhibitor of Lck, Prevents Heart Allograft Rejection
J Pharmacol Exp Ther 2005 315: 36-41. Published online July 12, 2005; 10.1124/jpet.105.089169 [Abstract] [Full Text] [PDF]  

Alf Lamprecht, Hiromitsu Yamamoto, Hirofumi Takeuchi, and Yoshiaki Kawashima
Nanoparticles Enhance Therapeutic Efficiency by Selectively Increased Local Drug Dose in Experimental Colitis in Rats
J Pharmacol Exp Ther 2005 315: 196-202. Published online June 24, 2005; 10.1124/jpet.105.088146 [Abstract] [Full Text] [PDF]  

Mark A. Pattoli, John F. MacMaster, Kurt R. Gregor, and James R. Burke
Collagen and Aggrecan Degradation Is Blocked in Interleukin-1-Treated Cartilage Explants by an Inhibitor of I{kappa}B Kinase through Suppression of Metalloproteinase Expression
J Pharmacol Exp Ther 2005 315: 382-388. Published online July 11, 2005; 10.1124/jpet.105.087569 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Rajesh Narendran, Dah-Ren Hwang, Mark Slifstein, Yuying Hwang, Yiyun Huang, Jesper Ekelund, Olivier Guillin, Erica Scher, Diana Martinez, and Marc Laruelle
Measurement of the Proportion of D2 Receptors Configured in State of High Affinity for Agonists in Vivo: A Positron Emission Tomography Study Using [11C]N-Propyl-norapomorphine and [11C]Raclopride in Baboons
J Pharmacol Exp Ther 2005 315: 80-90. Published online July 12, 2005; 10.1124/jpet.105.090068 [Abstract] [Full Text] [PDF]  

Yvan Dumont, Emmanuel Moyse, Alain Fournier, and Rémi Quirion
Evidence for the Existence of an Additional Class of Neuropeptide Y Receptor Sites in Rat Brain
J Pharmacol Exp Ther 2005 315: 99-108. Published online June 9, 2005; 10.1124/jpet.105.089300 [Abstract] [Full Text] [PDF]  

Renato Corradetti, Boris Mlinar, Chiara Falsini, Anna Maria Pugliese, Antonio Cilia, Carla Destefani, and Rodolfo Testa
Differential Effects of the 5-Hydroxytryptamine (5-HT)1A Receptor Inverse Agonists Rec 27/0224 and Rec 27/0074 on Electrophysiological Responses to 5-HT1A Receptor Activation in Rat Dorsal Raphe Nucleus and Hippocampus in Vitro
J Pharmacol Exp Ther 2005 315: 109-117. Published online June 10, 2005; 10.1124/jpet.105.087809 [Abstract] [Full Text] [PDF]  

Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z. Yeh, and Toshio Narahashi
Modulation of N-Methyl-D-aspartate Receptors by Donepezil in Rat Cortical Neurons
J Pharmacol Exp Ther 2005 315: 125-135. Published online June 10, 2005; 10.1124/jpet.105.087908 [Abstract] [Full Text] [PDF]  

Atsuyuki Kohara, Takashi Toya, Seiji Tamura, Tomonari Watabiki, Yukinori Nagakura, Yoshitsugu Shitaka, Satoshi Hayashibe, Shigeki Kawabata, and Masamichi Okada
Radioligand Binding Properties and Pharmacological Characterization of 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a High-Affinity, Selective, and Noncompetitive Antagonist of Metabotropic Glutamate Receptor Type 1
J Pharmacol Exp Ther 2005 315: 163-169. Published online June 23, 2005; 10.1124/jpet.105.087171 [Abstract] [Full Text] [PDF]  

Marcello Canonaco, Maria Madeo, Raffaella Alò, Giuseppina Giusi, Teresa Granata, Antonio Carelli, Alessia Canonaco, and Rosa Maria Facciolo
The Histaminergic Signaling System Exerts a Neuroprotective Role against Neurodegenerative-Induced Processes in the Hamster
J Pharmacol Exp Ther 2005 315: 188-195. Published online June 23, 2005; 10.1124/jpet.105.088153 [Abstract] [Full Text] [PDF]  

Michelle K. Winter and Kenneth E. McCarson
G-Protein Activation by Neurokinin-1 Receptors Is Dynamically Regulated during Persistent Nociception
J Pharmacol Exp Ther 2005 315: 214-221. Published online June 28, 2005; 10.1124/jpet.105.089565 [Abstract] [Full Text] [PDF]  

Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, and Adrian Newman-Tancredi
Contrasting Contribution of 5-Hydroxytryptamine 1A Receptor Activation to Neurochemical Profile of Novel Antipsychotics: Frontocortical Dopamine and Hippocampal Serotonin Release in Rat Brain
J Pharmacol Exp Ther 2005 315: 265-272. Published online June 29, 2005; 10.1124/jpet.105.087163 [Abstract] [Full Text] [PDF]  

Raji Mathew, Peethambaran Arun, Chikkathur N. Madhavarao, John R. Moffett, and M. A. Aryan Namboodiri
Progress toward Acetate Supplementation Therapy for Canavan Disease: Glyceryl Triacetate Administration Increases Acetate, but Not N-Acetylaspartate, Levels in Brain
J Pharmacol Exp Ther 2005 315: 297-303. Published online July 7, 2005; 10.1124/jpet.105.087536 [Abstract] [Full Text] [PDF]  

Petrine Wellendorph, Signe Høg, Jeremy R. Greenwood, Anne de Lichtenberg, Birgitte Nielsen, Bente Frølund, Lotte Brehm, Rasmus P. Clausen, and Hans Bräuner-Osborne
Novel Cyclic {gamma}-Hydroxybutyrate (GHB) Analogs with High Affinity and Stereoselectivity of Binding to GHB Sites in Rat Brain
J Pharmacol Exp Ther 2005 315: 346-351. Published online July 12, 2005; 10.1124/jpet.105.090472 [Abstract] [Full Text] [PDF] Data Supplement  

Shi-Bing Yang, Felix Major, Lutz F. Tietze, and Marjan Rupnik
Block of Delayed-Rectifier Potassium Channels by Reduced Haloperidol and Related Compounds in Mouse Cortical Neurons
J Pharmacol Exp Ther 2005 315: 352-362. Published online July 12, 2005; 10.1124/jpet.105.086561 [Abstract] [Full Text] [PDF]  

Kristen K. Ford, Michele Matchett, James E. Krause, and Weifeng Yu
The P2X3 Antagonist P1, P5-Di[inosine-5'] Pentaphosphate Binds to the Desensitized State of the Receptor in Rat Dorsal Root Ganglion Neurons
J Pharmacol Exp Ther 2005 315: 405-413. Published online July 13, 2005; 10.1124/jpet.105.088070 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Faneng Sun, Vellareddy Anantharam, Calivarathan Latchoumycandane, Arthi Kanthasamy, and Anumantha G. Kanthasamy
Dieldrin Induces Ubiquitin-Proteasome Dysfunction in {alpha}-Synuclein Overexpressing Dopaminergic Neuronal Cells and Enhances Susceptibility to Apoptotic Cell Death
J Pharmacol Exp Ther 2005 315: 69-79. Published online June 29, 2005; 10.1124/jpet.105.084632 [Abstract] [Full Text] [PDF]  

George A. Ricaurte, Annis O. Mechan, Jie Yuan, George Hatzidimitriou, Tao Xie, Andrew H. Mayne, and Una D. McCann
Amphetamine Treatment Similar to That Used in the Treatment of Adult Attention-Deficit/Hyperactivity Disorder Damages Dopaminergic Nerve Endings in the Striatum of Adult Nonhuman Primates
J Pharmacol Exp Ther 2005 315: 91-98. Published online July 13, 2005; 10.1124/jpet.105.087916 [Abstract] [Full Text] [PDF]  

Simona Magi, Pasqualina Castaldo, Giuseppina Carrieri, Antonella Scorziello, Gianfranco Di Renzo, and Salvatore Amoroso
Involvement of Na+-Ca2+ Exchanger in Intracellular Ca2+ Increase and Neuronal Injury Induced by Polychlorinated Biphenyls in Human Neuroblastoma SH-SY5Y Cells
J Pharmacol Exp Ther 2005 315: 291-296. Published online July 11, 2005; 10.1124/jpet.105.088948 [Abstract] [Full Text] [PDF]  

Irina G. Kessova and Arthur I. Cederbaum
The Effect of CYP2E1-Dependent Oxidant Stress on Activity of Proteasomes in HepG2 Cells
J Pharmacol Exp Ther 2005 315: 304-312. Published online July 7, 2005; 10.1124/jpet.105.088047 [Abstract] [Full Text] [PDF]  

ERRATA:

Correction to "Resistance of Human Astrocytoma Cells to Apoptosis Induced by Mitochondria-Damaging Agents: Possible Implications for Anticancer Therapy"
J Pharmacol Exp Ther 2005 315: 475. [Full Text] [PDF]  

Correction to "Effect of 4-(5-Chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a Novel Opener of Large Conductance Ca2+-Activated K+ (Maxi-K) Channels on Normal and Stress-Aggravated Colonic Motility and Visceral Nociception"
J Pharmacol Exp Ther 2005 315: 476. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the Cover:  Corneal neovascularization in transfected eyes. See the article by Mezentsev et al. on page 42 of this issue.



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