JPET Introducing ALZET?ew Model 2006 Pump

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Other Issues:
August 2005; 314 (2)   [Index by Author]  [Cover Caption]
       PERSPECTIVES IN PHARMACOLOGY
       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
       BEHAVIORAL PHARMACOLOGY
       CARDIOVASCULAR
       CELLULAR AND MOLECULAR
       CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
       INFLAMMATION AND IMMUNOPHARMACOLOGY
       NEUROPHARMACOLOGY
       TOXICOLOGY
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PERSPECTIVES IN PHARMACOLOGY:

Stuart Maudsley, Bronwen Martin, and Louis M. Luttrell
The Origins of Diversity and Specificity in G Protein-Coupled Receptor Signaling
J Pharmacol Exp Ther 2005 314: 485-494. Published online April 1, 2005; 10.1124/jpet.105.083121 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Cheng Chang, K. Sandy Pang, Peter W. Swaan, and Sean Ekins
Comparative Pharmacophore Modeling of Organic Anion Transporting Polypeptides: A Meta-Analysis of Rat Oatp1a1 and Human OATP1B1
J Pharmacol Exp Ther 2005 314: 533-541. Published online April 21, 2005; 10.1124/jpet.104.082370 [Abstract] [Full Text] [PDF] Data Supplement  

Martin S. Hoagland, Erica M. Hoagland, and Hollie I. Swanson
The p53 Inhibitor Pifithrin-{alpha} Is a Potent Agonist of the Aryl Hydrocarbon Receptor
J Pharmacol Exp Ther 2005 314: 603-610. Published online April 20, 2005; 10.1124/jpet.105.084186 [Abstract] [Full Text] [PDF]  

J. Steven Leeder, Roger Gaedigk, Kenda A. Marcucci, Andrea Gaedigk, Carrie A. Vyhlidal, Bradley P. Schindel, and Robin E. Pearce
Variability of CYP3A7 Expression in Human Fetal Liver
J Pharmacol Exp Ther 2005 314: 626-635. Published online April 21, 2005; 10.1124/jpet.105.086504 [Abstract] [Full Text] [PDF]  

Terrilyn A. Richardson and Edward T. Morgan
Hepatic Cytochrome P450 Gene Regulation during Endotoxin-Induced Inflammation in Nuclear Receptor Knockout Mice
J Pharmacol Exp Ther 2005 314: 703-709. Published online April 28, 2005; 10.1124/jpet.105.085456 [Abstract] [Full Text] [PDF]  

Akane Masuyama, Masuo Kondoh, Hirotoshi Seguchi, Azusa Takahashi, Motoki Harada, Makiko Fujii, Hiroyuki Mizuguchi, Yasuhiko Horiguchi, and Yoshiteru Watanabe
Role of N-Terminal Amino Acids in the Absorption-Enhancing Effects of the C-Terminal Fragment of Clostridium perfringens Enterotoxin
J Pharmacol Exp Ther 2005 314: 789-795. Published online May 3, 2005; 10.1124/jpet.105.085399 [Abstract] [Full Text] [PDF]  

Misaki Kuroda, Hiroyuki Kusuhara, Hitoshi Endou, and Yuichi Sugiyama
Rapid Elimination of Cefaclor from the Cerebrospinal Fluid Is Mediated by a Benzylpenicillin-Sensitive Mechanism Distinct from Organic Anion Transporter 3
J Pharmacol Exp Ther 2005 314: 855-861. Published online May 13, 2005; 10.1124/jpet.105.085027 [Abstract] [Full Text] [PDF]  

Masaru Hirano, Kazuya Maeda, Hisamitsu Hayashi, Hiroyuki Kusuhara, and Yuichi Sugiyama
Bile Salt Export Pump (BSEP/ABCB11) Can Transport a Nonbile Acid Substrate, Pravastatin
J Pharmacol Exp Ther 2005 314: 876-882. Published online May 18, 2005; 10.1124/jpet.105.084830 [Abstract] [Full Text] [PDF]  

Philip L. Lorenzi, Christopher P. Landowski, Xueqin Song, Katherine Z. Borysko, Julie M. Breitenbach, Jae Seung Kim, John M. Hilfinger, Leroy B. Townsend, John C. Drach, and Gordon L. Amidon
Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-({beta}-D-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo
J Pharmacol Exp Ther 2005 314: 883-890. Published online May 18, 2005; 10.1124/jpet.104.082412 [Abstract] [Full Text] [PDF]  

Tsuneo Deguchi, Mizue Takemoto, Nao Uehara, W. Edward Lindup, Ayaka Suenaga, and Masaki Otagiri
Renal Clearance of Endogenous Hippurate Correlates with Expression Levels of Renal Organic Anion Transporters in Uremic Rats
J Pharmacol Exp Ther 2005 314: 932-938. Published online May 5, 2005; 10.1124/jpet.105.085613 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Therese A. Kosten, Xiang Yang Zhang, and Priscilla Kehoe
Neurochemical and Behavioral Responses to Cocaine in Adult Male Rats with Neonatal Isolation Experience
J Pharmacol Exp Ther 2005 314: 661-667. Published online April 21, 2005; 10.1124/jpet.104.081216 [Abstract] [Full Text] [PDF]  

Erin E. Shannon, Patrizia Porcu, Robert H. Purdy, and Kathleen A. Grant
Characterization of the Discriminative Stimulus Effects of the Neuroactive Steroid Pregnanolone in DBA/2J and C57BL/6J Inbred Mice
J Pharmacol Exp Ther 2005 314: 675-685. Published online April 27, 2005; 10.1124/jpet.104.082644 [Abstract] [Full Text] [PDF]  

Barbara Langen, Ute Egerland, Katrin Bernöster, Rita Dost, Klaus Unverferth, and Chris Rundfeldt
Characterization in Rats of the Anxiolytic Potential of ELB139 [1-(4-Chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a New Agonist at the Benzodiazepine Binding Site of the GABAA Receptor
J Pharmacol Exp Ther 2005 314: 717-724. Published online April 28, 2005; 10.1124/jpet.105.084681 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Yan Wang, Xin Wei, Xiao Xiao, Rutai Hui, Jeffrey W. Card, Michelle A. Carey, Dao Wen Wang, and Darryl C. Zeldin
Arachidonic Acid Epoxygenase Metabolites Stimulate Endothelial Cell Growth and Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways
J Pharmacol Exp Ther 2005 314: 522-532. Published online April 19, 2005; 10.1124/jpet.105.083477 [Abstract] [Full Text] [PDF]  

Didi Omiyi, Richard J. Brue, Philip Taormina, II, Margaret Harvey, Norrell Atkinson, and Lindon H. Young
Protein Kinase C {beta}II Peptide Inhibitor Exerts Cardioprotective Effects in Rat Cardiac Ischemia/Reperfusion Injury
J Pharmacol Exp Ther 2005 314: 542-551. Published online May 5, 2005; 10.1124/jpet.104.082131 [Abstract] [Full Text] [PDF]  

D. Adam Lauver, Samuel F. Lockwood, and Benedict R. Lucchesi
Disodium Disuccinate Astaxanthin (Cardax) Attenuates Complement Activation and Reduces Myocardial Injury following Ischemia/Reperfusion
J Pharmacol Exp Ther 2005 314: 686-692. Published online May 4, 2005; 10.1124/jpet.105.087114 [Abstract] [Full Text] [PDF]  

James K. Hennan, Hassan Elokdah, Mauricio Leal, Allena Ji, Gregory S. Friedrichs, Gwen A. Morgan, Robert E. Swillo, Thomas M. Antrilli, Amy Hreha, and David L. Crandall
Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis
J Pharmacol Exp Ther 2005 314: 710-716. Published online April 28, 2005; 10.1124/jpet.105.084129 [Abstract] [Full Text] [PDF]  

Susana Y. Kamikihara, André Mueller, Vanessa Lima, Aderbal R. T. Silva, Isabela Bazzo da Costa, José Buratini, Jr., and André S. Pupo
Differential Distribution of Functional {alpha}1-Adrenergic Receptor Subtypes along the Rat Tail Artery
J Pharmacol Exp Ther 2005 314: 753-761. Published online May 4, 2005; 10.1124/jpet.105.087502 [Abstract] [Full Text] [PDF]  

Samarjit Das, Arpad Tosaki, Debasis Bagchi, Nilanjana Maulik, and Dipak K. Das
Resveratrol-Mediated Activation of cAMP Response Element-Binding Protein through Adenosine A3 Receptor by Akt-Dependent and -Independent Pathways
J Pharmacol Exp Ther 2005 314: 762-769. Published online May 5, 2005; 10.1124/jpet.105.084285 [Abstract] [Full Text] [PDF]  

Majid Malekzadeh Shafaroudi, Melissa McBride, Clare Deighan, Alexis Wokoma, Joyce Macmillan, Craig J. Daly, and John C. McGrath
Two "Knockout" Mouse Models Demonstrate That Aortic Vasodilatation Is Mediated via {alpha}2A-Adrenoceptors Located on the Endothelium
J Pharmacol Exp Ther 2005 314: 804-810. Published online May 5, 2005; 10.1124/jpet.105.085944 [Abstract] [Full Text] [PDF]  

Jing Li, Yu-Jung Chen, and John Quilley
Effect of Tempol on Renal Cyclooxygenase Expression and Activity in Experimental Diabetes in the Rat
J Pharmacol Exp Ther 2005 314: 818-824. Published online May 6, 2005; 10.1124/jpet.104.076927 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Jin-Sung Kim, Jin-Yong Park, Ho-Won Kang, Eun-Jung Lee, Hyoweon Bang, and Jung-Ha Lee
Zinc Activates TREK-2 Potassium Channel Activity
J Pharmacol Exp Ther 2005 314: 618-625. Published online April 27, 2005; 10.1124/jpet.105.084418 [Abstract] [Full Text] [PDF]  

Stefania Ceruti, Alessia Mazzola, and Maria P. Abbracchio
Resistance of Human Astrocytoma Cells to Apoptosis Induced by Mitochondria-Damaging Agents: Possible Implications for Anticancer Therapy
J Pharmacol Exp Ther 2005 314: 825-837. Published online May 5, 2005; 10.1124/jpet.105.085340 [Abstract] [Full Text] [PDF] Erratum  

Jennifer L. Shoemaker, Biny K. Joseph, Michael B. Ruckle, Philip R. Mayeux, and Paul L. Prather
The Endocannabinoid Noladin Ether Acts as a Full Agonist at Human CB2 Cannabinoid Receptors
J Pharmacol Exp Ther 2005 314: 868-875. Published online May 18, 2005; 10.1124/jpet.105.085282 [Abstract] [Full Text] [PDF]  

Johannes Bodenstein, Daniel P. Venter, and Christiaan B. Brink
Phenoxybenzamine and Benextramine, but Not 4-Diphenylacetoxy-N-[2-chloroethyl]piperidine Hydrochloride, Display Irreversible Noncompetitive Antagonism at G Protein-Coupled Receptors
J Pharmacol Exp Ther 2005 314: 891-905. Published online April 27, 2005; 10.1124/jpet.105.083568 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Zhi-Yuan Xu, Martin Loignon, Fei-Yu Han, Lawrence Panasci, and Raquel Aloyz
Xrcc3 Induces Cisplatin Resistance by Stimulation of Rad51-Related Recombinational Repair, S-Phase Checkpoint Activation, and Reduced Apoptosis
J Pharmacol Exp Ther 2005 314: 495-505. Published online April 20, 2005; 10.1124/jpet.105.084053 [Abstract] [Full Text] [PDF]  

Lalitha R. Belur, Rohaizah I. James, Chad May, Miechaleen D. Diers, Debra Swanson, Roland Gunther, and R. Scott McIvor
Methotrexate Preconditioning Allows Sufficient Engraftment to Confer Drug Resistance in Mice Transplanted with Marrow Expressing Drug-Resistant Dihydrofolate Reductase Activity
J Pharmacol Exp Ther 2005 314: 668-674. Published online April 27, 2005; 10.1124/jpet.104.082982 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Hiroshi Akahori, Tsuguhito Ota, Muneyoshi Torita, Hitoshi Ando, Shuichi Kaneko, and Toshinari Takamura
Tranilast Prevents the Progression of Experimental Diabetic Nephropathy through Suppression of Enhanced Extracellular Matrix Gene Expression
J Pharmacol Exp Ther 2005 314: 514-521. Published online April 27, 2005; 10.1124/jpet.105.084772 [Abstract] [Full Text] [PDF]  

Stefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, Barbara Renga, Andrea Mencarelli, Luisa Riccardi, Stefano Orlandi, Mark Pruzanski, Antonio Morelli, and Roberto Pellicciari
A Farnesoid X Receptor-Small Heterodimer Partner Regulatory Cascade Modulates Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloprotease Expression in Hepatic Stellate Cells and Promotes Resolution of Liver Fibrosis
J Pharmacol Exp Ther 2005 314: 584-595. Published online April 28, 2005; 10.1124/jpet.105.084905 [Abstract] [Full Text] [PDF]  

Daniel R. Kapusta, Melissa A. Burmeister, Girolamo Calo', Remo Guerrini, Helmut B. Gottlieb, and Velga A. Kenigs
Functional Selectivity of Nociceptin/Orphanin FQ Peptide Receptor Partial Agonists on Cardiovascular and Renal Function
J Pharmacol Exp Ther 2005 314: 643-651. Published online April 26, 2005; 10.1124/jpet.104.082768 [Abstract] [Full Text] [PDF]  

Daniel R. Kapusta, Christian Thorkildsen, Velga A. Kenigs, Eddi Meier, Mette M. Vinge, Charlotte Quist, and Jørgen Søberg Petersen
Pharmacodynamic Characterization of ZP120 (Ac-RYYRWKKKKKKK-NH2), a Novel, Functionally Selective Nociceptin/Orphanin FQ Peptide Receptor Partial Agonist with Sodium-Potassium-Sparing Aquaretic Activity
J Pharmacol Exp Ther 2005 314: 652-660. Published online April 26, 2005; 10.1124/jpet.105.083436 [Abstract] [Full Text] [PDF]  

Chatsri Deachapunya, Sutthasinee Poonyachoti, Watchareewan Thongsaard, and Nateetip Krishnamra
Barakol Extracted from Cassia siamea Stimulates Chloride Secretion in Rat Colon
J Pharmacol Exp Ther 2005 314: 732-737. Published online May 3, 2005; 10.1124/jpet.105.084210 [Abstract] [Full Text] [PDF]  

Trent M. Woodruff, Sandra Pollitt, Lavinia M. Proctor, Shelli Z. Stocks, Helga D. Manthey, Hua M. Williams, Indumathy B. Mahadevan, Ian A. Shiels, and Stephen M. Taylor
Increased Potency of a Novel Complement Factor 5a Receptor Antagonist in a Rat Model of Inflammatory Bowel Disease
J Pharmacol Exp Ther 2005 314: 811-817. Published online May 5, 2005; 10.1124/jpet.105.086835 [Abstract] [Full Text] [PDF]  

Susana Liu, Alain Veilleux, Lei Zhang, Andrew Young, Evonne Kwok, France Laliberté, Christine Chung, Michael R. Tota, Daniel Dubé, Richard W. Friesen, and Zheng Huang
Dynamic Activation of Cystic Fibrosis Transmembrane Conductance Regulator by Type 3 and Type 4D Phosphodiesterase Inhibitors
J Pharmacol Exp Ther 2005 314: 846-854. Published online May 18, 2005; 10.1124/jpet.105.083519 [Abstract] [Full Text] [PDF]  

Kelly Bleasby, Laura A. Hall, Jennifer L. Perry, Harvey W. Mohrenweiser, and John B. Pritchard
Functional Consequences of Single Nucleotide Polymorphisms in the Human Organic Anion Transporter hOAT1 (SLC22A6)
J Pharmacol Exp Ther 2005 314: 923-931. Published online May 24, 2005; 10.1124/jpet.105.084301 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Maria G. Belvisi, Daniela S. Bundschuh, Michael Stoeck, Sharon Wicks, Stephen Underwood, Clifford H. Battram, El-Bdaoui Haddad, Stephen E. Webber, and Martyn L. Foster
Preclinical Profile of Ciclesonide, a Novel Corticosteroid for the Treatment of Asthma
J Pharmacol Exp Ther 2005 314: 568-574. Published online May 5, 2005; 10.1124/jpet.105.085217 [Abstract] [Full Text] [PDF]  

Fiorentina Roviezzo, Stelios Tsigkos, Anastasia Kotanidou, Mariarosaria Bucci, Vincenzo Brancaleone, Giuseppe Cirino, and Andreas Papapetropoulos
Angiopoietin-2 Causes Inflammation in Vivo by Promoting Vascular Leakage
J Pharmacol Exp Ther 2005 314: 738-744. Published online May 3, 2005; 10.1124/jpet.105.086553 [Abstract] [Full Text] [PDF]  

Natsuko Kusunoki, Takumi Ito, Nobuyuki Sakurai, Toru Suguro, Hiroshi Handa, and Shinichi Kawai
A Novel Celecoxib Derivative Potently Induces Apoptosis of Human Synovial Fibroblasts
J Pharmacol Exp Ther 2005 314: 796-803. Published online May 3, 2005; 10.1124/jpet.105.086116 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Chris W. D. Jurgens, Katie E. Rau, Chris A. Knudson, Jacob D. King, Patrick A. Carr, James E. Porter, and Van A. Doze
{beta}1 Adrenergic Receptor-Mediated Enhancement of Hippocampal CA3 Network Activity
J Pharmacol Exp Ther 2005 314: 552-560. Published online May 20, 2005; 10.1124/jpet.105.085332 [Abstract] [Full Text] [PDF]  

Kristin L. Hillman, Van A. Doze, and James E. Porter
Functional Characterization of the {beta}-Adrenergic Receptor Subtypes Expressed by CA1 Pyramidal Cells in the Rat Hippocampus
J Pharmacol Exp Ther 2005 314: 561-567. Published online May 20, 2005; 10.1124/jpet.105.084947 [Abstract] [Full Text] [PDF]  

Okechukwu T. Ukairo, Corry D. Bondi, Amy Hauck Newman, Santosh S. Kulkarni, Alan P. Kozikowski, Stephen Pan, and Christopher K. Surratt
Recognition of Benztropine by the Dopamine Transporter (DAT) Differs from That of the Classical Dopamine Uptake Inhibitors Cocaine, Methylphenidate, and Mazindol as a Function of a DAT Transmembrane 1 Aspartic Acid Residue
J Pharmacol Exp Ther 2005 314: 575-583. Published online May 5, 2005; 10.1124/jpet.105.085829 [Abstract] [Full Text] [PDF]  

Jeffery N. Talbot, H. Kevin Happe, and L. Charles Murrin
µ Opioid Receptor Coupling to Gi/o Proteins Increases during Postnatal Development in Rat Brain
J Pharmacol Exp Ther 2005 314: 596-602. Published online April 28, 2005; 10.1124/jpet.104.082156 [Abstract] [Full Text] [PDF]  

Yan-Ping Chen, Shao-Rui Chen, and Hui-Lin Pan
Systemic Morphine Inhibits Dorsal Horn Projection Neurons through Spinal Cholinergic System Independent of Descending Pathways
J Pharmacol Exp Ther 2005 314: 611-617. Published online April 21, 2005; 10.1124/jpet.105.085563 [Abstract] [Full Text] [PDF]  

P. R. Lockman, G. McAfee, W. J. Geldenhuys, C. J. Van der Schyf, T. J. Abbruscato, and D. D. Allen
Brain Uptake Kinetics of Nicotine and Cotinine after Chronic Nicotine Exposure
J Pharmacol Exp Ther 2005 314: 636-642. Published online April 21, 2005; 10.1124/jpet.105.085381 [Abstract] [Full Text] [PDF]  

Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, and Yvette Michotte
Quantitative in Vivo Microdialysis Study on the Influence of Multidrug Transporters on the Blood-Brain Barrier Passage of Oxcarbazepine: Concomitant Use of Hippocampal Monoamines as Pharmacodynamic Markers for the Anticonvulsant Activity
J Pharmacol Exp Ther 2005 314: 725-731. Published online April 28, 2005; 10.1124/jpet.105.085514 [Abstract] [Full Text] [PDF]  

Claire-Marie Rangon, Stéphanie Goursaud, Fadia Medja, Vincent Lelièvre, Lourdes Mounien, Isabelle Husson, Philippe Brabet, Sylvie Jégou, Thierry Janet, and Pierre Gressens
VPAC2 Receptors Mediate Vasoactive Intestinal Peptide-Induced Neuroprotection against Neonatal Excitotoxic Brain Lesions in Mice
J Pharmacol Exp Ther 2005 314: 745-752. Published online May 4, 2005; 10.1124/jpet.105.086405 [Abstract] [Full Text] [PDF]  

Yun Liu, Guang-Di Chen, Megan R. Lerner, Daniel J. Brackett, and Rae R. Matsumoto
Cocaine Up-Regulates Fra-2 and {sigma}-1 Receptor Gene and Protein Expression in Brain Regions Involved in Addiction and Reward
J Pharmacol Exp Ther 2005 314: 770-779. Published online May 5, 2005; 10.1124/jpet.105.084525 [Abstract] [Full Text] [PDF]  

Carol Hamelink, Aidan Hampson, David A. Wink, Lee E. Eiden, and Robert L. Eskay
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
J Pharmacol Exp Ther 2005 314: 780-788. Published online May 5, 2005; 10.1124/jpet.105.085779 [Abstract] [Full Text] [PDF]  

V. González-Nuñez, G. Arsequell, E. Szemenyei, G. Toth, G. Valencia, and R. E. Rodriguez
Binding Profile of the Endogenous Novel Heptapeptide Met-Enkephalin-Gly-Tyr in Zebrafish and Rat Brain
J Pharmacol Exp Ther 2005 314: 862-867. Published online May 18, 2005; 10.1124/jpet.105.084558 [Abstract] [Full Text] [PDF]  

Barbara Nightingale, Christina M. Dersch, Terrence L. Boos, Elisabeth Greiner, William J. Calhoun, Arthur E. Jacobson, Kenner C. Rice, and Richard B. Rothman
Studies of the Biogenic Amine Transporters. XI. Identification of a 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) Analog That Allosterically Modulates the Serotonin Transporter
J Pharmacol Exp Ther 2005 314: 906-915. Published online April 28, 2005; 10.1124/jpet.105.084376 [Abstract] [Full Text] [PDF]  

Kota Ishida, Mikio Murata, Nobuyuki Katagiri, Masago Ishikawa, Kenji Abe, Masatoshi Kato, Iku Utsunomiya, and Kyoji Taguchi
Effects of {beta}-Phenylethylamine on Dopaminergic Neurons of the Ventral Tegmental Area in the Rat: A Combined Electrophysiological and Microdialysis Study
J Pharmacol Exp Ther 2005 314: 916-922. Published online May 5, 2005; 10.1124/jpet.105.084764 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Andrew J. Phimister, Kurt J. Williams, Laura S. Van Winkle, and Charles G. Plopper
Consequences of Abrupt Glutathione Depletion in Murine Clara Cells: Ultrastructural and Biochemical Investigations into the Role of Glutathione Loss in Naphthalene Cytotoxicity
J Pharmacol Exp Ther 2005 314: 506-513. Published online April 21, 2005; 10.1124/jpet.105.084533 [Abstract] [Full Text] [PDF]  

J. van Grevenynghe, M. Bernard, S. Langouet, C. Le Berre, T. Fest, and O. Fardel
Human CD34-Positive Hematopoietic Stem Cells Constitute Targets for Carcinogenic Polycyclic Aromatic Hydrocarbons
J Pharmacol Exp Ther 2005 314: 693-702. Published online April 28, 2005; 10.1124/jpet.105.084780 [Abstract] [Full Text] [PDF]  

Zachary S. Bowman, Jason D. Morrow, David J. Jollow, and David C. McMillan
Primaquine-Induced Hemolytic Anemia: Role of Membrane Lipid Peroxidation and Cytoskeletal Protein Alterations in the Hemotoxicity of 5-Hydroxyprimaquine
J Pharmacol Exp Ther 2005 314: 838-845. Published online April 19, 2005; 10.1124/jpet.105.086488 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the Cover:  Confocal microscopic localization of WT and D79 mutant DAT proteins. See the article by Ukairo et al. on page 575 of this issue.



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