PERSPECTIVES IN PHARMACOLOGY:

Eve C. Feinberg, Jason G. Bromer, and William H. Catherino

The Evolution of in Vitro Fertilization: Integration of Pharmacology, Technology, and Clinical Care
J Pharmacol Exp Ther 2005 313: 935-942. Published online March 15, 2005; 10.1124/jpet.104.080051 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

S. K. Quinney, S. P. Sanghani, W. I. Davis, T. D. Hurley, Z. Sun, D. J. Murry, and W. F. Bosron

Hydrolysis of Capecitabine to 5'-Deoxy-5-fluorocytidine by Human Carboxylesterases and Inhibition by Loperamide
J Pharmacol Exp Ther 2005 313: 1011-1016. Published online February 1, 2005; 10.1124/jpet.104.081265 [Abstract] [Full Text] [PDF]  

Ashish Sharma, Philippe Pibarot, Sylvie Pilote, Jean G. Dumesnil, Marie Arsenault, Pierre Maxime Bélanger, Bernd Meibohm, and Bettina A. Hamelin

Modulation of Metoprolol Pharmacokinetics and Hemodynamics by Diphenhydramine Coadministration during Exercise Testing in Healthy Premenopausal Women
J Pharmacol Exp Ther 2005 313: 1172-1181. Published online February 17, 2005; 10.1124/jpet.104.081109 [Abstract] [Full Text] [PDF]  

Marilyn E. Morris, Ke Hu, and Qi Wang

Renal Clearance of -Hydroxybutyric Acid in Rats: Increasing Renal Elimination as a Detoxification Strategy
J Pharmacol Exp Ther 2005 313: 1194-1202. Published online February 18, 2005; 10.1124/jpet.105.083253 [Abstract] [Full Text] [PDF]  

Robert P. Hanzlik, Stephen C. Fowler, and Daniel H. Fisher

Relative Bioavailability of Calcium from Calcium Formate, Calcium Citrate, and Calcium Carbonate
J Pharmacol Exp Ther 2005 313: 1217-1222. Published online February 25, 2005; 10.1124/jpet.104.081893 [Abstract] [Full Text] [PDF]  

Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc, and Jeffery Van Deusen

Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding
J Pharmacol Exp Ther 2005 313: 1254-1262. Published online March 2, 2005; 10.1124/jpet.104.079319 [Abstract] [Full Text] [PDF]  

Soundararajan Krishnaswamy, Qin Hao, Abdul Al-Rohaimi, Leah M. Hesse, Lisa L. von Moltke, David J. Greenblatt, and Michael H. Court

UDP Glucuronosyltransferase (UGT) 1A6 Pharmacogenetics: I. Identification of Polymorphisms in the 5'-Regulatory and Exon 1 Regions, and Association with Human Liver UGT1A6 Gene Expression and Glucuronidation
J Pharmacol Exp Ther 2005 313: 1331-1339. Published online March 10, 2005; 10.1124/jpet.104.081950 [Abstract] [Full Text] [PDF]  

Soundararajan Krishnaswamy, Qin Hao, Abdul Al-Rohaimi, Leah M. Hesse, Lisa L. von Moltke, David J. Greenblatt, and Michael H. Court

UDP Glucuronosyltransferase (UGT) 1A6 Pharmacogenetics: II. Functional Impact of the Three Most Common Nonsynonymous UGT1A6 Polymorphisms (S7A, T181A, and R184S)
J Pharmacol Exp Ther 2005 313: 1340-1346. Published online March 10, 2005; 10.1124/jpet.104.081968 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Stephanie C. Licata, Donna M. Platt, James M. Cook, P. V. V. Srirama Sarma, Guy Griebel, and James K. Rowlett

Contribution of GABA_A Receptor Subtypes to the Anxiolytic-Like, Motor, and Discriminative Stimulus Effects of Benzodiazepines: Studies with the Functionally Selective Ligand SL651498 [6-Fluoro-9-methyl-2-phenyl-4-(pyrrolidin-1-yl-carbonyl)-2,9-dihydro-1H-pyridol[3,4-b]indol-1-one]
J Pharmacol Exp Ther 2005 313: 1118-1125. Published online February 1, 2005; 10.1124/jpet.104.081612 [Abstract] [Full Text] [PDF]  

Kirsten M. Raehal, John J. Lowery, Castigliano M. Bhamidipati, Ryan M. Paolino, Jennifer R. Blair, Danxin Wang, Wolfgang Sadée, and Edward J. Bilsky

In Vivo Characterization of 6-Naltrexol, an Opioid Ligand with Less Inverse Agonist Activity Compared with Naltrexone and Naloxone in Opioid-Dependent Mice
J Pharmacol Exp Ther 2005 313: 1150-1162. Published online February 16, 2005; 10.1124/jpet.104.082966 [Abstract] [Full Text] [PDF]  

Su-Min Li, Amy Hauck Newman, and Jonathan L. Katz

Place Conditioning and Locomotor Effects of N-Substituted, 4',4''-Difluorobenztropine Analogs in Rats
J Pharmacol Exp Ther 2005 313: 1223-1230. Published online March 2, 2005; 10.1124/jpet.105.084541 [Abstract] [Full Text] [PDF]  

Lawrence P. Carter, Huifang Wu, Weibin Chen, Marilyn M. Matthews, Ashok K. Mehta, R. Jason Hernandez, Jennifer A. Thomson, Maharaj K. Ticku, Andrew Coop, Wouter Koek, and Charles P. France

Novel -Hydroxybutyric Acid (GHB) Analogs Share Some, but Not All, of the Behavioral Effects of GHB and GABA_B Receptor Agonists
J Pharmacol Exp Ther 2005 313: 1314-1323. Published online March 15, 2005; 10.1124/jpet.104.077578 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Soghra Fatima, Fariborz A. Yaghini, Zoran Pavicevic, Shailaja Kalyankrishna, Nauzanene Jafari, Elizabeth Luong, Anne Estes, and Kafait U. Malik

Intact Actin Filaments Are Required for Cytosolic Phospholipase A₂ Translocation but Not for Its Activation by Norepinephrine in Vascular Smooth Muscle Cells
J Pharmacol Exp Ther 2005 313: 1017-1026. Published online February 10, 2005; 10.1124/jpet.104.081992 [Abstract] [Full Text] [PDF] Data Supplement  

Yelena A. Shmist, Roman Kamburg, Gal Ophir, Alex Kozak, Vladimir Shneyvays, Yori J. Appelbaum, and Asher Shainberg

N,N,N',N'-Tetrakis(2-pyridylmethyl)-ethylenediamine Improves Myocardial Protection against Ischemia by Modulation of Intracellular Ca²+ Homeostasis
J Pharmacol Exp Ther 2005 313: 1046-1057. Published online January 28, 2005; 10.1124/jpet.104.081281 [Abstract] [Full Text] [PDF]  

Chiara Bolego, Andrea Cignarella, Paola Sanvito, Valeria Pelosi, Fabio Pellegatta, Lina Puglisi, and Christian Pinna

The Acute Estrogenic Dilation of Rat Aorta Is Mediated Solely by Selective Estrogen Receptor- Agonists and Is Abolished by Estrogen Deprivation
J Pharmacol Exp Ther 2005 313: 1203-1208. Published online February 18, 2005; 10.1124/jpet.104.082867 [Abstract] [Full Text] [PDF]  

Klaudia Budzyn, Philip D. Marley, and Christopher G. Sobey

Opposing Roles of Endothelial and Smooth Muscle Phosphatidylinositol 3-Kinase in Vasoconstriction: Effects of Rho-Kinase and Hypertension
J Pharmacol Exp Ther 2005 313: 1248-1253. Published online March 2, 2005; 10.1124/jpet.104.082784 [Abstract] [Full Text] [PDF]  

Adebayo O. Oyekan

Differential Effects of 20-Hydroxyeicosatetraenoic Acid on Intrarenal Blood Flow in the Rat
J Pharmacol Exp Ther 2005 313: 1289-1295. Published online March 15, 2005; 10.1124/jpet.104.080218 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

A. Banan, L. J. Zhang, M. Shaikh, J. Z. Fields, S. Choudhary, C. B. Forsyth, A. Farhadi, and A. Keshavarzian

Isoform of Protein Kinase C Alters Barrier Function in Intestinal Epithelium through Modulation of Distinct Claudin Isotypes: A Novel Mechanism for Regulation of Permeability
J Pharmacol Exp Ther 2005 313: 962-982. Published online March 10, 2005; 10.1124/jpet.105.083428 [Abstract] [Full Text] [PDF]  

Chris R. Guthrie, Aaron T. Murray, Allyn A. Franklin, and Mark W. Hamblin

Differential Agonist-Mediated Internalization of the Human 5-Hydroxytryptamine 7 Receptor Isoforms
J Pharmacol Exp Ther 2005 313: 1003-1010. Published online February 16, 2005; 10.1124/jpet.104.081919 [Abstract] [Full Text] [PDF]  

Wakako Hamabe, Ryousuke Fujita, and Hiroshi Ueda

Insulin Receptor-Protein Kinase C- Signaling Mediates Inhibition of Hypoxia-Induced Necrosis of Cortical Neurons
J Pharmacol Exp Ther 2005 313: 1027-1034. Published online February 10, 2005; 10.1124/jpet.104.082735 [Abstract] [Full Text] [PDF] Data Supplement  

De-Pei Li and Hui-Lin Pan

Angiotensin II Attenuates Synaptic GABA Release and Excites Paraventricular-Rostral Ventrolateral Medulla Output Neurons
J Pharmacol Exp Ther 2005 313: 1035-1045. Published online January 28, 2005; 10.1124/jpet.104.082495 [Abstract] [Full Text] [PDF]  

Jillian G. Baker

Site of Action of -Ligands at the Human 1-Adrenoceptor
J Pharmacol Exp Ther 2005 313: 1163-1171. Published online February 16, 2005; 10.1124/jpet.104.082875 [Abstract] [Full Text] [PDF]  

Sarah A. Nickolls, Beth Fleck, Sam R. J. Hoare, and Rich A. Maki

Functional Selectivity of Melanocortin 4 Receptor Peptide and Nonpeptide Agonists: Evidence for Ligand-Specific Conformational States
J Pharmacol Exp Ther 2005 313: 1281-1288. Published online March 2, 2005; 10.1124/jpet.105.083337 [Abstract] [Full Text] [PDF]  

V. J. Bennett, S. A. Perrine, and M. A. Simmons

Neurokinin-1 Receptor Resensitization Precedes Receptor Recycling
J Pharmacol Exp Ther 2005 313: 1347-1354. Published online March 11, 2005; 10.1124/jpet.104.079954 [Abstract] [Full Text] [PDF]  

Leen Thielemans, Inge Depoortere, Jason Perret, Patrick Robberecht, Yaoquan Liu, Theo Thijs, Chris Carreras, Emmanuel Burgeon, and Theo L. Peeters

Desensitization of the Human Motilin Receptor by Motilides
J Pharmacol Exp Ther 2005 313: 1397-1405. Published online March 11, 2005; 10.1124/jpet.104.081497 [Abstract] [Full Text] [PDF]  

T. Z. Su, M. R. Feng, and M. L. Weber

Mediation of Highly Concentrative Uptake of Pregabalin by L-Type Amino Acid Transport in Chinese Hamster Ovary and Caco-2 Cells
J Pharmacol Exp Ther 2005 313: 1406-1415. Published online March 15, 2005; 10.1124/jpet.104.082255 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Eugene T. Grygielko, William M. Martin, Christopher Tweed, Peter Thornton, John Harling, David P. Brooks, and Nicholas J. Laping

Inhibition of Gene Markers of Fibrosis with a Novel Inhibitor of Transforming Growth Factor- Type I Receptor Kinase in Puromycin-Induced Nephritis
J Pharmacol Exp Ther 2005 313: 943-951. Published online March 15, 2005; 10.1124/jpet.104.082099 [Abstract] [Full Text] [PDF]  

Erwin Biecker, Andrea De Gottardi, Markus Neef, Matthias Unternährer, Vreni Schneider, Monika Ledermann, Hans Sägesser, Sidney Shaw, and Jürg Reichen

Long-Term Treatment of Bile Duct-Ligated Rats with Rapamycin (Sirolimus) Significantly Attenuates Liver Fibrosis: Analysis of the Underlying Mechanisms
J Pharmacol Exp Ther 2005 313: 952-961. Published online March 15, 2005; 10.1124/jpet.104.079616 [Abstract] [Full Text] [PDF]  

Dinesh Gautam, Sung-Jun Han, Thomas S. Heard, Yinghong Cui, Georgina Miller, Lanh Bloodworth, and Jürgen Wess

Cholinergic Stimulation of Amylase Secretion from Pancreatic Acinar Cells Studied with Muscarinic Acetylcholine Receptor Mutant Mice
J Pharmacol Exp Ther 2005 313: 995-1002. Published online March 11, 2005; 10.1124/jpet.105.084855 [Abstract] [Full Text] [PDF]  

Bunzo Matsuura, Maoqing Dong, Bernard Coulie, Delia I. Pinon, and Laurence J. Miller

Demonstration of a Specific Site of Covalent Labeling of the Human Motilin Receptor Using a Biologically Active Photolabile Motilin Analog
J Pharmacol Exp Ther 2005 313: 1101-1108. Published online January 26, 2005; 10.1124/jpet.104.081562 [Abstract] [Full Text] [PDF]  

C. Jane Dixon, Pamela J. White, John F. Hall, Shaun Kingston, and Michael R. Boarder

Regulation of Human Hepatocytes by P2Y Receptors: Control of Glycogen Phosphorylase, Ca²⁺, and Mitogen-Activated Protein Kinases
J Pharmacol Exp Ther 2005 313: 1305-1313. Published online March 11, 2005; 10.1124/jpet.104.082743 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Stephen B. Phagoo, Krisanavane Reddi, Bertrand J. Silvallana, L. M. Fredrik Leeb-Lundberg, and David Warburton

Infection-Induced Kinin B₁ Receptors in Human Pulmonary Fibroblasts: Role of Intact Pathogens and p38 Mitogen-Activated Protein Kinase-Dependent Signaling
J Pharmacol Exp Ther 2005 313: 1231-1238. Published online March 2, 2005; 10.1124/jpet.104.083030 [Abstract] [Full Text] [PDF]  

Christopher E. Heise, Anil Pahuja, Sarah C. Hudson, Monica S. Mistry, Amy L. Putnam, Molly M. Gross, Peter A. Gottlieb, Warren S. Wade, Mehrak Kiankarimi, David Schwarz, Paul Crowe, Albert Zlotnik, and David G. Alleva

Pharmacological Characterization of CXC Chemokine Receptor 3 Ligands and a Small Molecule Antagonist
J Pharmacol Exp Ther 2005 313: 1263-1271. Published online March 10, 2005; 10.1124/jpet.105.083683 [Abstract] [Full Text] [PDF]  

Facundo Germán Pelorosso, Paula Tamara Brodsky, Camila Lidia Zold, and Rodolfo Pedro Rothlin

Potentiation of des-Arg⁹-Kallidin-Induced Vasoconstrictor Responses by Metallopeptidase Inhibition in Isolated Human Umbilical Artery
J Pharmacol Exp Ther 2005 313: 1355-1360. Published online March 11, 2005; 10.1124/jpet.105.083063 [Abstract] [Full Text] [PDF]  

Christianne Bandeira-Melo, André Gustavo C. Bonavita, Bruno L. Diaz, Patricia M. R. e Silva, Vinícius F. Carvalho, Peter J. Jose, Roderick J. Flower, Mauro Perretti, and Marco A. Martins

A Novel Effect for Annexin 1-Derived Peptide Ac2-26: Reduction of Allergic Inflammation in the Rat
J Pharmacol Exp Ther 2005 313: 1416-1422. Published online March 22, 2005; 10.1124/jpet.104.080473 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Gregory M. Miller, Christopher D. Verrico, Amy Jassen, Martha Konar, Hong Yang, Helen Panas, Mary Bahn, Ryan Johnson, and Bertha K. Madras

Primate Trace Amine Receptor 1 Modulation by the Dopamine Transporter
J Pharmacol Exp Ther 2005 313: 983-994. Published online March 11, 2005; 10.1124/jpet.105.084459 [Abstract] [Full Text] [PDF]  

Leo Kinarsky, Bihua Feng, Donald A. Skifter, Richard M. Morley, Simon Sherman, David E. Jane, and Daniel T. Monaghan

Identification of Subunit- and Antagonist-Specific Amino Acid Residues in the N-Methyl-D-aspartate Receptor Glutamate-Binding Pocket
J Pharmacol Exp Ther 2005 313: 1066-1074. Published online March 2, 2005; 10.1124/jpet.104.082990 [Abstract] [Full Text] [PDF]  

Yun Zhang and William M. Pardridge

Delivery of -Galactosidase to Mouse Brain via the Blood-Brain Barrier Transferrin Receptor
J Pharmacol Exp Ther 2005 313: 1075-1081. Published online February 17, 2005; 10.1124/jpet.104.082974 [Abstract] [Full Text] [PDF]  

Eugenia Bloch-Shilderman, Tamar Kadar, Aharon Levy, Rita Sahar, Ishai Rabinovitz, and Eran Gilat

Subcellular Alterations of Protein Kinase C Isozymes in the Rat Brain after Organophosphate Poisoning
J Pharmacol Exp Ther 2005 313: 1082-1089. Published online February 16, 2005; 10.1124/jpet.105.083469 [Abstract] [Full Text] [PDF]  

James J. Ley, Alexey Vigdorchik, Ludmila Belayev, Weizhao Zhao, Raul Busto, Larissa Khoutorova, David A. Becker, and Myron D. Ginsberg

Stilbazulenyl Nitrone, a Second-Generation Azulenyl Nitrone Antioxidant, Confers Enduring Neuroprotection in Experimental Focal Cerebral Ischemia in the Rat: Neurobehavior, Histopathology, and Pharmacokinetics
J Pharmacol Exp Ther 2005 313: 1090-1100. Published online February 16, 2005; 10.1124/jpet.105.083386 [Abstract] [Full Text] [PDF]  

A. Gardner, T. C. Westfall, and H. Macarthur

Endothelin (ET)-1-Induced Inhibition of ATP Release from PC-12 Cells Is Mediated by the ET_B Receptor: Differential Response to ET-1 on ATP, Neuropeptide Y, and Dopamine Levels
J Pharmacol Exp Ther 2005 313: 1109-1117. Published online February 1, 2005; 10.1124/jpet.104.081075 [Abstract] [Full Text] [PDF]  

Catherine M. Gliddon, Cynthia L. Darlington, and Paul F. Smith

Effects of Chronic Infusion of a GABA_A Receptor Agonist or Antagonist into the Vestibular Nuclear Complex on Vestibular Compensation in the Guinea Pig
J Pharmacol Exp Ther 2005 313: 1126-1135. Published online February 1, 2005; 10.1124/jpet.104.082172 [Abstract] [Full Text] [PDF]  

Ashraf Yassen, Erik Olofsen, Albert Dahan, and Meindert Danhof

Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine and Fentanyl in Rats: Role of Receptor Equilibration Kinetics
J Pharmacol Exp Ther 2005 313: 1136-1149. Published online February 8, 2005; 10.1124/jpet.104.082560 [Abstract] [Full Text] [PDF]  

J. McDaid, J. E. Dallimore, A. R. Mackie, A. L. Mickiewicz, and T. C. Napier

Cross-Sensitization to Morphine in Cocaine-Sensitized Rats: Behavioral Assessments Correlate with Enhanced Responding of Ventral Pallidal Neurons to Morphine and Glutamate, with Diminished Effects of GABA
J Pharmacol Exp Ther 2005 313: 1182-1193. Published online February 18, 2005; 10.1124/jpet.105.084038 [Abstract] [Full Text] [PDF]  

M. O. Urban, K. Ren, K. T. Park, B. Campbell, N. Anker, B. Stearns, J. Aiyar, M. Belley, C. Cohen, and L. Bristow

Comparison of the Antinociceptive Profiles of Gabapentin and 3-Methylgabapentin in Rat Models of Acute and Persistent Pain: Implications for Mechanism of Action
J Pharmacol Exp Ther 2005 313: 1209-1216. Published online February 25, 2005; 10.1124/jpet.104.081778 [Abstract] [Full Text] [PDF]  

V. L. Tawfik, M. L. LaCroix-Fralish, N. Nutile-McMenemy, and J. A. DeLeo

Transcriptional and Translational Regulation of Glial Activation by Morphine in a Rodent Model of Neuropathic Pain
J Pharmacol Exp Ther 2005 313: 1239-1247. Published online March 2, 2005; 10.1124/jpet.104.082420 [Abstract] [Full Text] [PDF]  

Murat Oz, Shelley N. Jackson, Amina S. Woods, Marisela Morales, and Li Zhang

Additive Effects of Endogenous Cannabinoid Anandamide and Ethanol on ₇-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
J Pharmacol Exp Ther 2005 313: 1272-1280. Published online February 1, 2005; 10.1124/jpet.104.081315 [Abstract] [Full Text] [PDF]  

Ornella Valenti, Guido Mannaioni, Guy R. Seabrook, P. Jeffrey Conn, and Michael J. Marino

Group III Metabotropic Glutamate-Receptor-Mediated Modulation of Excitatory Transmission in Rodent Substantia Nigra Pars Compacta Dopamine Neurons
J Pharmacol Exp Ther 2005 313: 1296-1304. Published online March 10, 2005; 10.1124/jpet.104.080481 [Abstract] [Full Text] [PDF]  

Patrick Osei-Owusu, Amy James, James Crane, and Karie E. Scrogin

5-Hydroxytryptamine 1A Receptors in the Paraventricular Nucleus of the Hypothalamus Mediate Oxytocin and Adrenocorticotropin Hormone Release and Some Behavioral Components of the Serotonin Syndrome
J Pharmacol Exp Ther 2005 313: 1324-1330. Published online March 2, 2005; 10.1124/jpet.104.082073 [Abstract] [Full Text] [PDF]  

Richard B. Rothman, Bruce E. Blough, William L. Woolverton, Karen G. Anderson, S. Stevens Negus, Nancy K. Mello, Bryan L. Roth, and Michael H. Baumann

Development of a Rationally Designed, Low Abuse Potential, Biogenic Amine Releaser That Suppresses Cocaine Self-Administration
J Pharmacol Exp Ther 2005 313: 1361-1369. Published online March 10, 2005; 10.1124/jpet.104.082503 [Abstract] [Full Text] [PDF]  

Karunya K. Kandimalla, Geoffry L. Curran, Silvina S. Holasek, Emily J. Gilles, Thomas M. Wengenack, and Joseph F. Poduslo

Pharmacokinetic Analysis of the Blood-Brain Barrier Transport of ¹²⁵I-Amyloid Protein 40 in Wild-Type and Alzheimer's Disease Transgenic Mice (APP,PS1) and Its Implications for Amyloid Plaque Formation
J Pharmacol Exp Ther 2005 313: 1370-1378. Published online March 2, 2005; 10.1124/jpet.104.081901 [Abstract] [Full Text] [PDF]  

Michael R. Brandt, Terri A. Cummons, Lisa Potestio, Stacey J. Sukoff, and Sharon Rosenzweig-Lipson

Effects of the N-Methyl-D-aspartate Receptor Antagonist Perzinfotel [EAA-090; [2-(8,9-Dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic Acid] on Chemically Induced Thermal Hypersensitivity
J Pharmacol Exp Ther 2005 313: 1379-1386. Published online March 11, 2005; 10.1124/jpet.105.084467 [Abstract] [Full Text] [PDF]  

Hongling Zhang and Javier Cuevas

Receptor Activation Blocks Potassium Channels and Depresses Neuroexcitability in Rat Intracardiac Neurons
J Pharmacol Exp Ther 2005 313: 1387-1396. Published online March 11, 2005; 10.1124/jpet.105.084152 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Dean J. Naisbitt, John Farrell, Peter J. Chamberlain, Josephine E. Hopkins, Neil G. Berry, Munir Pirmohamed, and B. Kevin Park

Characterization of the T-Cell Response in a Patient with Phenindione Hypersensitivity
J Pharmacol Exp Ther 2005 313: 1058-1065. Published online March 2, 2005; 10.1124/jpet.105.083758 [Abstract] [Full Text] [PDF]  

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