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Cover Caption
Other Issues:
September 2004; 310 (3)   [Index by Author]  [Cover Caption]
       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
       BEHAVIORAL PHARMACOLOGY
       CARDIOVASCULAR
       CELLULAR AND MOLECULAR
       CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
       INFLAMMATION AND IMMUNOPHARMACOLOGY
       NEUROPHARMACOLOGY
       TOXICOLOGY
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ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin, and Joyce A. Goldstein
CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
J Pharmacol Exp Ther 2004 310: 845-854. Published online April 14, 2004; 10.1124/jpet.104.067819 [Abstract] [Full Text] [PDF]  

Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae, and Paul F. Hollenberg
Metabolism of N,N',N''-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
J Pharmacol Exp Ther 2004 310: 1011-1019. Published online April 30, 2004; 10.1124/jpet.104.069112 [Abstract] [Full Text] [PDF]  

Zeruesenay Desta, Bryan A. Ward, Nadia V. Soukhova, and David A. Flockhart
Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6
J Pharmacol Exp Ther 2004 310: 1062-1075. Published online May 24, 2004; 10.1124/jpet.104.065607 [Abstract] [Full Text] [PDF]  

Ken-ichiro Matsumoto, Murali C. Krishna, and James B. Mitchell
Novel Pharmacokinetic Measurement Using Electron Paramagnetic Resonance Spectroscopy and Simulation of in Vivo Decay of Various Nitroxyl Spin Probes in Mouse Blood
J Pharmacol Exp Ther 2004 310: 1076-1083. Published online April 22, 2004; 10.1124/jpet.104.066647 [Abstract] [Full Text] [PDF]  

Xiaobin Jia, Jun Chen, Huimin Lin, and Ming Hu
Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates
J Pharmacol Exp Ther 2004 310: 1103-1113. Published online May 5, 2004; 10.1124/jpet.104.068403 [Abstract] [Full Text] [PDF]  

Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen, and Rodney J. Y. Ho
Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
J Pharmacol Exp Ther 2004 310: 1199-1207. Published online April 20, 2004; 10.1124/jpet.104.065383 [Abstract] [Full Text] [PDF]  

Neal L. Benowitz, Brenda Herrera, and Peyton Jacob, III
Mentholated Cigarette Smoking Inhibits Nicotine Metabolism
J Pharmacol Exp Ther 2004 310: 1208-1215. Published online April 14, 2004; 10.1124/jpet.104.066902 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann, and Will P. J. M. Spooren
Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
J Pharmacol Exp Ther 2004 310: 952-963. Published online April 27, 2004; 10.1124/jpet.104.066753 [Abstract] [Full Text] [PDF]  

Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale, and George F. Koob
Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
J Pharmacol Exp Ther 2004 310: 1027-1034. Published online April 28, 2004; 10.1124/jpet.104.068676 [Abstract] [Full Text] [PDF]  

N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton, and O. Curet
SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
J Pharmacol Exp Ther 2004 310: 1171-1182. Published online June 3, 2004; 10.1124/jpet.103.064782 [Abstract] [Full Text] [PDF]  

Malgorzata Filip, Marcy J. Bubar, and Kathryn A. Cunningham
Contribution of Serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2 Receptor Subtypes to the Hyperlocomotor Effects of Cocaine: Acute and Chronic Pharmacological Analyses
J Pharmacol Exp Ther 2004 310: 1246-1254. Published online May 6, 2004; 10.1124/jpet.104.068841 [Abstract] [Full Text] [PDF]  

Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard, and John L. Waddington
Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3',5'-Monophosphate-Regulated Phosphoprotein of 32 kDa "Knockout" Mutants Congenic on the C57BL/6 Genetic Background
J Pharmacol Exp Ther 2004 310: 1281-1287. Published online May 12, 2004; 10.1124/jpet.104.068957 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Huige Li, Ning Xia, Isolde Brausch, Ying Yao, and Ulrich Förstermann
Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
J Pharmacol Exp Ther 2004 310: 926-932. Published online May 3, 2004; 10.1124/jpet.104.066639 [Abstract] [Full Text] [PDF]  

Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers, and Vincent D'Orio
Effect of BM-573 [N-Terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
J Pharmacol Exp Ther 2004 310: 964-972. Published online April 30, 2004; 10.1124/jpet.104.066852 [Abstract] [Full Text] [PDF]  

Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki, and Ikunobu Muramatsu
Identification of {alpha}-1L Adrenoceptor in Rabbit Ear Artery
J Pharmacol Exp Ther 2004 310: 995-1002. Published online April 20, 2004; 10.1124/jpet.104.066985 [Abstract] [Full Text] [PDF]  

Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti, and Michele D'Amico
The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
J Pharmacol Exp Ther 2004 310: 1133-1141. Published online April 27, 2004; 10.1124/jpet.104.068726 [Abstract] [Full Text] [PDF]  

Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis, and Hendrik Buikema
Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
J Pharmacol Exp Ther 2004 310: 1183-1189. Published online June 2, 2004; 10.1124/jpet.104.067272 [Abstract] [Full Text] [PDF]  

Naz Chaudary, Zlatina Naydenova, Irina Shuralyova, and Imogen R. Coe
The Adenosine Transporter, mENT1, Is a Target for Adenosine Receptor Signaling and Protein Kinase C{epsilon} in Hypoxic and Pharmacological Preconditioning in the Mouse Cardiomyocyte Cell Line, HL-1
J Pharmacol Exp Ther 2004 310: 1190-1198. Published online May 6, 2004; 10.1124/jpet.104.067157 [Abstract] [Full Text] [PDF]  

Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown, and Terence Bennett
Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-L-tyrosine Peroxisome Proliferator-Activated Receptor-{gamma} Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
J Pharmacol Exp Ther 2004 310: 1226-1233. Published online May 4, 2004; 10.1124/jpet.104.068817 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Brian D. Schlag, Zhuangwei Lou, Myles Fennell, and John Dunlop
Ligand Dependency of 5-Hydroxytryptamine 2C Receptor Internalization
J Pharmacol Exp Ther 2004 310: 865-870. Published online April 27, 2004; 10.1124/jpet.104.067306 [Abstract] [Full Text] [PDF]  

G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder, and S. Pippig
In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
J Pharmacol Exp Ther 2004 310: 896-904. Published online June 9, 2004; 10.1124/jpet.104.067611 [Abstract] [Full Text] [PDF]  

Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson, and Peter H. Yu
Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
J Pharmacol Exp Ther 2004 310: 1125-1132. Published online May 5, 2004; 10.1124/jpet.104.068601 [Abstract] [Full Text] [PDF]  

Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski, and R. A. John Challiss
Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
J Pharmacol Exp Ther 2004 310: 1255-1265. Published online May 12, 2004; 10.1124/jpet.104.067140 [Abstract] [Full Text] [PDF]  

Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto, and Masatomo Mori
Fenofibrate, Troglitazone, and 15-Deoxy-{Delta}12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
J Pharmacol Exp Ther 2004 310: 1273-1280. Published online June 16, 2004; 10.1124/jpet.104.067249 [Abstract] [Full Text] [PDF]  

Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe, and Yasushi Ohizumi
IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
J Pharmacol Exp Ther 2004 310: 1288-1295. Published online May 25, 2004; 10.1124/jpet.104.065979 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams, and Daniela M. Zisterer
Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
J Pharmacol Exp Ther 2004 310: 1084-1095. Published online May 13, 2004; 10.1124/jpet.104.067561 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Samuel A. Mantey, David H. Coy, Laurence K. Entsuah, and Robert T. Jensen
Development of Bombesin Analogs with Conformationally Restricted Amino Acid Substitutions with Enhanced Selectivity for the Orphan Receptor Human Bombesin Receptor Subtype 3
J Pharmacol Exp Ther 2004 310: 1161-1170. Published online April 21, 2004; 10.1124/jpet.104.066761 [Abstract] [Full Text] [PDF]  

Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor, and Paul C. Dolber
Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
J Pharmacol Exp Ther 2004 310: 1266-1272. Published online May 19, 2004; 10.1124/jpet.103.063842 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli, and Luciana Mussoni
Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
J Pharmacol Exp Ther 2004 310: 890-895. Published online June 16, 2004; 10.1124/jpet.104.067090 [Abstract] [Full Text] [PDF]  

Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó, and D. Craig Hooper
The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
J Pharmacol Exp Ther 2004 310: 1053-1061. Published online May 24, 2004; 10.1124/jpet.103.063214 [Abstract] [Full Text] [PDF]  

John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato, and Stefano Fiorucci
Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-{kappa}B
J Pharmacol Exp Ther 2004 310: 1096-1102. Published online May 5, 2004; 10.1124/jpet.104.067850 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay, and Robert J. DeLorenzo
Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
J Pharmacol Exp Ther 2004 310: 871-880. Published online April 14, 2004; 10.1124/jpet.104.068478 [Abstract] [Full Text] [PDF]  

Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié, and Gérard Le Fur
SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
J Pharmacol Exp Ther 2004 310: 905-914. Published online May 6, 2004; 10.1124/jpet.104.067884 [Abstract] [Full Text] [PDF]  

Bela Szabo, Marta Than, David Thorn, and Ilka Wallmichrath
Analysis of the Effects of Cannabinoids on Synaptic Transmission between Basket and Purkinje Cells in the Cerebellar Cortex of the Rat
J Pharmacol Exp Ther 2004 310: 915-925. Published online May 3, 2004; 10.1124/jpet.104.066670 [Abstract] [Full Text] [PDF]  

Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh, and Toshio Narahashi
Mechanism of Action of Galantamine on N-Methyl-D-Aspartate Receptors in Rat Cortical Neurons
J Pharmacol Exp Ther 2004 310: 933-942. Published online April 30, 2004; 10.1124/jpet.104.067603 [Abstract] [Full Text] [PDF]  

Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell, and Robert E. Davis
Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
J Pharmacol Exp Ther 2004 310: 943-951. Published online April 21, 2004; 10.1124/jpet.104.066688 [Abstract] [Full Text] [PDF]  

Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi, and Beáta Sperlágh
P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
J Pharmacol Exp Ther 2004 310: 973-980. Published online April 14, 2004; 10.1124/jpet.104.066712 [Abstract] [Full Text] [PDF]  

Yury Grabovsky and Ronald J. Tallarida
Isobolographic Analysis for Combinations of a Full and Partial Agonist: Curved Isoboles
J Pharmacol Exp Ther 2004 310: 981-986. Published online June 2, 2004; 10.1124/jpet.104.067264 [Abstract] [Full Text] [PDF]  

Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya, and Manuela G. López
ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with "Calcium Promotor" and Neuroprotective Properties
J Pharmacol Exp Ther 2004 310: 987-994. Published online April 26, 2004; 10.1124/jpet.104.068189 [Abstract] [Full Text] [PDF]  

Feng Chen and Andrew J. Lawrence
Chronic Antidepressant Treatment Causes a Selective Reduction of µ-Opioid Receptor Binding and Functional Coupling to G Proteins in the Amygdala of Fawn-Hooded Rats
J Pharmacol Exp Ther 2004 310: 1020-1026. Published online April 30, 2004; 10.1124/jpet.104.068692 [Abstract] [Full Text] [PDF]  

Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm, and Linda P. Dwoskin
Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
J Pharmacol Exp Ther 2004 310: 1035-1045. Published online April 30, 2004; 10.1124/jpet.104.068098 [Abstract] [Full Text] [PDF]  

Yang Gao and Stephen Brimijoin
An Engineered Cocaine Hydrolase Blunts and Reverses Cardiovascular Responses to Cocaine in Rats
J Pharmacol Exp Ther 2004 310: 1046-1052. Published online April 20, 2004; 10.1124/jpet.104.068122 [Abstract] [Full Text] [PDF]  

Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka, and Seitaro Mutoh
A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
J Pharmacol Exp Ther 2004 310: 1114-1124. Published online April 27, 2004; 10.1124/jpet.104.068932 [Abstract] [Full Text] [PDF]  

Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman, and Aaron Janowsky
Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
J Pharmacol Exp Ther 2004 310: 1142-1151. Published online April 21, 2004; 10.1124/jpet.104.067314 [Abstract] [Full Text] [PDF]  

Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales, and Carl R. Lupica
Differential Effects of Endogenous and Synthetic Cannabinoids on {alpha}7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
J Pharmacol Exp Ther 2004 310: 1152-1160. Published online April 21, 2004; 10.1124/jpet.104.067751 [Abstract] [Full Text] [PDF]  

Jessica L. Reynolds, Tracey A. Ignatowski, Reeteka Sud, and Robert N. Spengler
Brain-Derived Tumor Necrosis Factor-{alpha} and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant
J Pharmacol Exp Ther 2004 310: 1216-1225. Published online April 13, 2004; 10.1124/jpet.104.067835 [Abstract] [Full Text] [PDF]  

Jing Liang, Elisabetta Cagetti, Richard W. Olsen, and Igor Spigelman
Altered Pharmacology of Synaptic and Extrasynaptic GABAA Receptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence
J Pharmacol Exp Ther 2004 310: 1234-1245. Published online May 4, 2004; 10.1124/jpet.104.067983 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost, and Poh-Gek Forkert
Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
J Pharmacol Exp Ther 2004 310: 855-864. Published online May 3, 2004; 10.1124/jpet.104.068171 [Abstract] [Full Text] [PDF]  

Hiroshi Ishida, Xieping Zhang, Kelly Erickson, and Prabhati Ray
Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in Nerve Growth Factor-Treated PC12 Cells
J Pharmacol Exp Ther 2004 310: 881-889. Published online May 12, 2004; 10.1124/jpet.104.065318 [Abstract] [Full Text] [PDF]  

Lisa M. Kaminskas, Simon M. Pyke, and Philip C. Burcham
Strong Protein Adduct Trapping Accompanies Abolition of Acrolein-Mediated Hepatotoxicity by Hydralazine in Mice
J Pharmacol Exp Ther 2004 310: 1003-1010. Published online May 6, 2004; 10.1124/jpet.104.067330 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Internalization and subcellular localization of muM17. See the article by Coffey et al. on page 896 of this issue.


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