PERSPECTIVES IN PHARMACOLOGY:

Jing-Yu Chang

Brain Stimulation for Neurological and Psychiatric Disorders, Current Status and Future Direction
J Pharmacol Exp Ther 2004 309: 1-7. Published online January 16, 2004; 10.1124/jpet.103.049718 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Xiao-Yan Chu, Su-E. W. Huskey, Matthew P. Braun, Balazs Sarkadi, David C. Evans, and Raymond Evers

Transport of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate by the Multidrug Resistance Proteins MRP1, MRP2, and MRP3
J Pharmacol Exp Ther 2004 309: 156-164. Published online January 13, 2004; 10.1124/jpet.103.062091 [Abstract] [Full Text] [PDF]  

Yoshitane Nozaki, Hiroyuki Kusuhara, Hitoshi Endou, and Yuichi Sugiyama

Quantitative Evaluation of the Drug-Drug Interactions between Methotrexate and Nonsteroidal Anti-Inflammatory Drugs in the Renal Uptake Process Based on the Contribution of Organic Anion Transporters and Reduced Folate Carrier
J Pharmacol Exp Ther 2004 309: 226-234. Published online January 13, 2004; 10.1124/jpet.103.061812 [Abstract] [Full Text] [PDF]  

V. D. Awasthi, D. Garcia, R. Klipper, B. A. Goins, and W. T. Phillips

Neutral and Anionic Liposome-Encapsulated Hemoglobin: Effect of Postinserted Poly(ethylene glycol)-distearoylphosphatidylethanolamine on Distribution and Circulation Kinetics
J Pharmacol Exp Ther 2004 309: 241-248. Published online January 12, 2004; 10.1124/jpet.103.060228 [Abstract] [Full Text] [PDF]  

Jessica B. Mills, Kelly A. Rose, Nalini Sadagopan, Jasminder Sahi, and Sonia M. F. de Morais

Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line
J Pharmacol Exp Ther 2004 309: 303-309. Published online January 13, 2004; 10.1124/jpet.103.061713 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Cassandra Y. Baskfield, Billy R. Martin, and Jenny L. Wiley

Differential Effects of ⁹-Tetrahydrocannabinol and Methanandamide in CB1 Knockout and Wild-Type Mice
J Pharmacol Exp Ther 2004 309: 86-91. Published online January 12, 2004; 10.1124/jpet.103.055376 [Abstract] [Full Text] [PDF]  

Hoang-Thanh Le, Irma B. Lemaire, Annie-Kim Gilbert, François Jolicoeur, Lin Yang, Natacha Leduc, and Simon Lemaire

Histogranin-Like Antinociceptive and Anti-Inflammatory Derivatives of o-Phenylenediamine and Benzimidazole
J Pharmacol Exp Ther 2004 309: 146-155. Published online January 12, 2004; 10.1124/jpet.103.060772 [Abstract] [Full Text] [PDF]  

Emily M. Jutkiewicz, Erik B. Eller, John E. Folk, Kenner C. Rice, John R. Traynor, and James H. Woods

-Opioid Agonists: Differential Efficacy and Potency of SNC80, Its 3-OH (SNC86) and 3-Desoxy (SNC162) Derivatives in Sprague-Dawley Rats
J Pharmacol Exp Ther 2004 309: 173-181. Published online January 13, 2004; 10.1124/jpet.103.061242 [Abstract] [Full Text] [PDF]  

Andrea Gogos and Maarten Van den Buuse

Estrogen and Progesterone Prevent Disruption of Prepulse Inhibition by the Serotonin-1A Receptor Agonist 8-Hydroxy-2-dipropylaminotetralin
J Pharmacol Exp Ther 2004 309: 267-274. Published online January 13, 2004; 10.1124/jpet.103.061432 [Abstract] [Full Text] [PDF]  

Snjezana Lelas, Harvey Wong, Yu-Wen Li, Karen L. Heman, Kathryn A. Ward, Kim L. Zeller, Kristine K. Sieracki, Joseph L. Polino, Helen E. Godonis, Shelly X. Ren, Xiao-Xin Yan, Stephen P. Arneric, David W. Robertson, Paul R. Hartig, Scott Grossman, George L. Trainor, Rebecca A. Taub, Robert Zaczek, Paul J. Gilligan, and John F. McElroy

Anxiolytic-Like Effects of the Corticotropin-Releasing Factor₁ (CRF₁) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF₁ Receptors in Rats
J Pharmacol Exp Ther 2004 309: 293-302. Published online January 23, 2004; 10.1124/jpet.103.058784 [Abstract] [Full Text] [PDF]  

Yunden Jinsmaa, Yoshio Okada, Yuko Tsuda, Kimitaka Shiotani, Yusuke Sasaki, Akihiro Ambo, Sharon D. Bryant, and Lawrence H. Lazarus

Novel 2',6'-Dimethyl-L-Tyrosine-Containing Pyrazinone Opioid Mimetic µ-Agonists with Potent Antinociceptive Activity in Mice
J Pharmacol Exp Ther 2004 309: 432-438. Published online January 12, 2004; 10.1124/jpet.103.060061 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Kenneth W. L. Kam, Jian Song Qi, Mai Chen, and Tak Ming Wong

Estrogen Reduces Cardiac Injury and Expression of ₁-Adrenoceptor upon Ischemic Insult in the Rat Heart
J Pharmacol Exp Ther 2004 309: 8-15. Published online January 12, 2004; 10.1124/jpet.103.058339 [Abstract] [Full Text] [PDF]  

Christof Burgdorf, Andreas Dendorfer, Thomas Kurz, Edgar Schömig, Ines Stölting, Frank Schütte, and Gert Richardt

Role of Neuronal K_ATP Channels and Extraneuronal Monoamine Transporter on Norepinephrine Overflow in a Model of Myocardial Low Flow Ischemia
J Pharmacol Exp Ther 2004 309: 42-48. Published online January 12, 2004; 10.1124/jpet.103.059832 [Abstract] [Full Text] [PDF]  

Véronique Leblais, Fabrice Pourageaud, M. Dolores Ivorra, Christelle Guibert, Roger Marthan, and Bernard Muller

Role of -Adrenergic Receptors in the Effect of the -Adrenergic Receptor Ligands, CGP 12177, Bupranolol, and SR 59230A, on the Contraction of Rat Intrapulmonary Artery
J Pharmacol Exp Ther 2004 309: 137-145. Published online January 12, 2004; 10.1124/jpet.103.061192 [Abstract] [Full Text] [PDF]  

Stephanie W. Watts and Janice M. Thompson

Characterization of the Contractile 5-Hydroxytryptamine Receptor in the Renal Artery of the Normotensive Rat
J Pharmacol Exp Ther 2004 309: 165-172. Published online January 14, 2004; 10.1124/jpet.103.062562 [Abstract] [Full Text] [PDF]  

George E. Billman, Melanie S. Houle, Heinrich C. Englert, and Heinz Gögelein

Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]--methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia: In Vitro and in Vivo Studies
J Pharmacol Exp Ther 2004 309: 182-192. Published online January 13, 2004; 10.1124/jpet.103.061416 [Abstract] [Full Text] [PDF]  

Janine Lorrain, Irène Lechaire, Christiane Gauffeny, Régis Masson, Nigel Roome, Jean-Pascal Herault, Stephen Eric O'Connor, Paul Schaeffer, and Jean-Marc Herbert

Effects of SanOrg123781A, a Synthetic Hexadecasaccharide, in a Mouse Model of Electrically Induced Carotid Artery Injury: Synergism with the Antiplatelet Agent Clopidogrel
J Pharmacol Exp Ther 2004 309: 235-240. Published online January 12, 2004; 10.1124/jpet.103.059873 [Abstract] [Full Text] [PDF]  

Mark C. Kowala, Natesan Murugesan, John Tellew, Kenneth Carlson, Hossain Monshizadegan, Carol Ryan, Zhengxiang Gu, Bridgette Kane, Leena Fadnis, Rose Ann Baska, Sophie Beyer, Susan Arthur, Kenneth Dickinson, Donglu Zhang, Mark Perrone, Pam Ferrer, Mary Giancarli, Jergen Baumann, Eileen Bird, Balkrushna Panchal, Yifan Yang, Nick Trippodo, Joel Barrish, and John E. Macor

Novel Dual Action AT₁ and ET_A Receptor Antagonists Reduce Blood Pressure in Experimental Hypertension
J Pharmacol Exp Ther 2004 309: 275-284. Published online January 12, 2004; 10.1124/jpet.103.055855 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Robert E. Carraway, Sazzad Hassan, and David E. Cochrane

Polyphenolic Antioxidants Mimic the Effects of 1,4-Dihydropyridines on Neurotensin Receptor Function in PC3 Cells
J Pharmacol Exp Ther 2004 309: 92-101. Published online January 12, 2004; 10.1124/jpet.103.060442 [Abstract] [Full Text] [PDF]  

Luping Huang, Brian M. Keyser, Tina M. Tagmose, J. Bondo Hansen, James T. Taylor, Hean Zhuang, Min Zhang, David S. Ragsdale, and Ming Li

NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-Benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A New Selective Inhibitor of T-Type Calcium Channels
J Pharmacol Exp Ther 2004 309: 193-199. Published online January 12, 2004; 10.1124/jpet.103.060814 [Abstract] [Full Text] [PDF]  

Mauro Cataldi, Annarita Gaudino, Vincenzo Lariccia, Michela Russo, Salvatore Amoroso, Gianfranco di Renzo, and Lucio Annunziato

Imatinib-Mesylate Blocks Recombinant T-Type Calcium Channels Expressed in Human Embryonic Kidney-293 Cells by a Protein Tyrosine Kinase-Independent Mechanism
J Pharmacol Exp Ther 2004 309: 208-215. Published online January 12, 2004; 10.1124/jpet.103.061184 [Abstract] [Full Text] [PDF]  

Malika Israilova, Takashi Tanaka, Fumiko Suzuki, Shigeru Morishima, and Ikunobu Muramatsu

Pharmacological Characterization and Cross Talk of _1A- and _1B-Adrenoceptors Coexpressed in Human Embryonic Kidney 293 Cells
J Pharmacol Exp Ther 2004 309: 259-266. Published online January 13, 2004; 10.1124/jpet.103.061796 [Abstract] [Full Text] [PDF]  

A. Banan, L. J. Zhang, M. Shaikh, J. Z. Fields, A. Farhadi, and A. Keshavarzian

Inhibition of Oxidant-Induced Nuclear Factor-B Activation and Inhibitory-B Degradation and Instability of F-Actin Cytoskeletal Dynamics and Barrier Function by Epidermal Growth Factor: Key Role of Phospholipase- Isoform
J Pharmacol Exp Ther 2004 309: 356-368. Published online January 14, 2004; 10.1124/jpet.103.062232 [Abstract] [Full Text] [PDF]  

Chris Hague, Zhongjian Chen, Andre S. Pupo, Nancy A. Schulte, Myron L. Toews, and Kenneth P. Minneman

The N Terminus of the Human _1D-Adrenergic Receptor Prevents Cell Surface Expression
J Pharmacol Exp Ther 2004 309: 388-397. Published online January 12, 2004; 10.1124/jpet.103.060509 [Abstract] [Full Text] [PDF]  

Bradley T. Andresen, Guillermo G. Romero, and Edwin K. Jackson

AT₂ Receptors Attenuate AT₁ Receptor-Induced Phospholipase D Activation in Vascular Smooth Muscle Cells
J Pharmacol Exp Ther 2004 309: 425-431. Published online January 13, 2004; 10.1124/jpet.103.061846 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Yusheng Han, Hongmei Shen, Brian I. Carr, Peter Wipf, John S. Lazo, and Su-shu Pan

NAD(P)H:Quinone Oxidoreductase-1-Dependent and -Independent Cytotoxicity of Potent Quinone Cdc25 Phosphatase Inhibitors
J Pharmacol Exp Ther 2004 309: 64-70. Published online January 12, 2004; 10.1124/jpet.103.059477 [Abstract] [Full Text] [PDF]  

Kevin J. French, Yan Zhuang, Randy S. Schrecengost, Jean E. Copper, Zuping Xia, and Charles D. Smith

Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-Based Inhibitors of Human N-Myristoyltransferase-1
J Pharmacol Exp Ther 2004 309: 340-347. Published online January 14, 2004; 10.1124/jpet.103.061572 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND REPRODUCTIVE:

Jude E. Onyia, Rachelle J. Sells Galvin, Yanfei L. Ma, David L. Halladay, Rebecca R. Miles, Xuhao Yang, Tina Fuson, Ricky L. Cain, Qing Qiang Zeng, S. Chandrasekhar, Renee Emkey, Yanping Xu, Kannan Thirunavukkarasu, Henry U. Bryant, and T. John Martin

Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption
J Pharmacol Exp Ther 2004 309: 369-379. Published online January 12, 2004; 10.1124/jpet.103.057893 [Abstract] [Full Text] [PDF]  

Claudine Serradeil-Le Gal, Gérard Valette, Loïc Foulon, Guy Germain, Charles Advenier, Emmanuel Naline, Marc Bardou, Jean-Pierre Martinolle, Brigitte Pouzet, Danielle Raufaste, Corinne Garcia, Eléonore Double-Cazanave, Maxime Pauly, Marc Pascal, Alain Barbier, Bernard Scatton, Jean-Pierre Maffrand, and Gérard Le Fur

SSR126768A (4-Chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, Hydrochloride): A New Selective and Orally Active Oxytocin Receptor Antagonist for the Prevention of Preterm Labor
J Pharmacol Exp Ther 2004 309: 414-424. Published online January 13, 2004; 10.1124/jpet.103.061200 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Linda Metzner, Jutta Kalbitz, and Matthias Brandsch

Transport of Pharmacologically Active Proline Derivatives by the Human Proton-Coupled Amino Acid Transporter hPAT1
J Pharmacol Exp Ther 2004 309: 28-35. Published online January 12, 2004; 10.1124/jpet.103.059014 [Abstract] [Full Text] [PDF]  

Hong-Zhen Hu, Na Gao, Sumei Liu, Jun Ren, Yun Xia, and Jackie D. Wood

Metabotropic Signal Transduction for Bradykinin in Submucosal Neurons of Guinea Pig Small Intestine
J Pharmacol Exp Ther 2004 309: 310-319. Published online January 12, 2004; 10.1124/jpet.103.059204 [Abstract] [Full Text] [PDF]  

Hong-Zhen Hu, Na Gao, Sumei Liu, Jun Ren, Xiyu Wang, Yun Xia, and Jackie D. Wood

Action of Bradykinin in the Submucosal Plexus of Guinea Pig Small Intestine
J Pharmacol Exp Ther 2004 309: 320-327. Published online January 12, 2004; 10.1124/jpet.103.059188 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Courtney E. W. Sulentic, Wei Zhang, Yong Joo Na, and Norbert E. Kaminski

2,3,7,8-Tetrachlorodibenzo-p-dioxin, an Exogenous Modulator of the 3' Immunoglobulin Heavy Chain Enhancer in the CH12.LX Mouse Cell Line
J Pharmacol Exp Ther 2004 309: 71-78. Published online January 12, 2004; 10.1124/jpet.103.059493 [Abstract] [Full Text] [PDF]  

Denis J. Dupré, Christian Le Gouill, Denis Gingras, Marek Rola-Pleszczynski, and Jana Stanková

Inverse Agonist Activity of Selected Ligands of the Cysteinyl-Leukotriene Receptor 1
J Pharmacol Exp Ther 2004 309: 102-108. Published online January 12, 2004; 10.1124/jpet.103.059824 [Abstract] [Full Text] [PDF]  

Shaoheng He, Akhmed Aslam, Marianna D. A. Gaça, Yongsong He, Mark G. Buckley, Morley D. Hollenberg, and Andrew F. Walls

Inhibitors of Tryptase as Mast Cell-Stabilizing Agents in the Human Airways: Effects of Tryptase and Other Agonists of Proteinase-Activated Receptor 2 on Histamine Release
J Pharmacol Exp Ther 2004 309: 119-126. Published online January 13, 2004; 10.1124/jpet.103.061291 [Abstract] [Full Text] [PDF]  

Michael Stoeck, Richard Riedel, Günther Hochhaus, Dietrich Häfner, José M. Masso, Beate Schmidt, Armin Hatzelmann, Degenhard Marx, and Daniela S. Bundschuh

In Vitro and in Vivo Anti-Inflammatory Activity of the New Glucocorticoid Ciclesonide
J Pharmacol Exp Ther 2004 309: 249-258. Published online January 12, 2004; 10.1124/jpet.103.059592 [Abstract] [Full Text] [PDF]  

Roberta Pacifici, Simona Pichini, Piergiorgio Zuccaro, Magí Farré, Mireia Segura, Jordi Ortuño, Simonetta Di Carlo, Antonella Bacosi, Pere N. Roset, Jordi Segura, and Rafael de la Torre

Paroxetine Inhibits Acute Effects of 3,4-Methylenedioxymethamphetamine on the Immune System in Humans
J Pharmacol Exp Ther 2004 309: 285-292. Published online January 13, 2004; 10.1124/jpet.103.061374 [Abstract] [Full Text] [PDF]  

Jin Y. Jin, Debra C. DuBois, Richard R. Almon, and William J. Jusko

Receptor/Gene-Mediated Pharmacodynamic Effects of Methylprednisolone on Phosphoenolpyruvate Carboxykinase Regulation in Rat Liver
J Pharmacol Exp Ther 2004 309: 328-339. Published online January 13, 2004; 10.1124/jpet.103.061515 [Abstract] [Full Text] [PDF]  

Yuhua Zhang, Jun Xu, Jeremy Levin, Martin Hegen, Guangde Li, Heidi Robertshaw, Fionula Brennan, Terri Cummons, Dave Clarke, Nichole Vansell, Cheryl Nickerson-Nutter, Dauphine Barone, Ken Mohler, Roy Black, Jerry Skotnicki, Jay Gibbons, Marc Feldmann, Philip Frost, Glenn Larsen, and Lih-Ling Lin

Identification and Characterization of 4-[[4-(2-Butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a Novel Dual Tumor Necrosis Factor--Converting Enzyme/Matrix Metalloprotease Inhibitor for the Treatment of Rheumatoid Arthritis
J Pharmacol Exp Ther 2004 309: 348-355. Published online January 12, 2004; 10.1124/jpet.103.059675 [Abstract] [Full Text] [PDF]  

Travis J. Jerde, William S. Mellon, Susan M. Fischer, Monica Liebert, Dale E. Bjorling, and Stephen Y. Nakada

Suppression of 15-Hydroxyprostaglandin Dehydrogenase Messenger RNA Concentration, Protein Expression, and Enzymatic Activity during Human Ureteral Obstruction
J Pharmacol Exp Ther 2004 309: 398-403. Published online January 12, 2004; 10.1124/jpet.103.056929 [Abstract] [Full Text] [PDF]  

Robin L. Thurmond, Pragnya J. Desai, Paul J. Dunford, Wai-Ping Fung-Leung, Claudia L. Hofstra, Wen Jiang, Steven Nguyen, Jason P. Riley, Siquan Sun, Kacy N. Williams, James P. Edwards, and Lars Karlsson

A Potent and Selective Histamine H₄ Receptor Antagonist with Anti-Inflammatory Properties
J Pharmacol Exp Ther 2004 309: 404-413. Published online January 13, 2004; 10.1124/jpet.103.061754 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Mario B. Marrero, Roger L. Papke, Balwinder S. Bhatti, Seán Shaw, and Merouane Bencherif

The Neuroprotective Effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a Novel 7 Ligand, Is Prevented through Angiotensin II Activation of a Tyrosine Phosphatase
J Pharmacol Exp Ther 2004 309: 16-27. Published online January 13, 2004; 10.1124/jpet.103.061655 [Abstract] [Full Text] [PDF]  

Ichiro Takasaki, Tomohiko Suzuki, Atsushi Sasaki, Kaoru Nakao, Mikito Hirakata, Kiyoshi Okano, Toshiaki Tanaka, Hiroshi Nagase, Kimiyasu Shiraki, Hiroshi Nojima, and Yasushi Kuraishi

Suppression of Acute Herpetic Pain-Related Responses by the -Opioid Receptor Agonist (-)-17-Cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[N-methyl-3-trans-3-(3-furyl) Acrylamido] Morphinan Hydrochloride (TRK-820) in Mice
J Pharmacol Exp Ther 2004 309: 36-41. Published online January 7, 2004; 10.1124/jpet.103.059816 [Abstract] [Full Text] [PDF]  

Thomas A. Lanz, John D. Hosley, Wade J. Adams, and Kalpana M. Merchant

Studies of A Pharmacodynamics in the Brain, Cerebrospinal Fluid, and Plasma in Young (Plaque-Free) Tg2576 Mice Using the -Secretase Inhibitor N²-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N¹-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY-411575)
J Pharmacol Exp Ther 2004 309: 49-55. Published online January 12, 2004; 10.1124/jpet.103.060715 [Abstract] [Full Text] [PDF]  

S. Akerman, H. Kaube, and P. J. Goadsby

Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception
J Pharmacol Exp Ther 2004 309: 56-63. Published online January 12, 2004; 10.1124/jpet.103.059808 [Abstract] [Full Text] [PDF]  

Massimo Pierucci, Vincenzo Di Matteo, and Ennio Esposito

Stimulation of Serotonin_2C Receptors Blocks the Hyperactivation of Midbrain Dopamine Neurons Induced by Nicotine Administration
J Pharmacol Exp Ther 2004 309: 109-118. Published online January 13, 2004; 10.1124/jpet.103.062208 [Abstract] [Full Text] [PDF]  

Mutsumi Ueda, Ryousuke Fujita, Takehiko Koji, and Hiroshi Ueda

The Cognition-Enhancer Nefiracetam Inhibits Both Necrosis and Apoptosis in Retinal Ischemic Models in Vitro and in Vivo
J Pharmacol Exp Ther 2004 309: 200-207. Published online January 12, 2004; 10.1124/jpet.103.061127 [Abstract] [Full Text] [PDF]  

R. J. Thielen, E. A. Engleman, Z. A. Rodd, J. M. Murphy, L. Lumeng, T.-K. Li, and W. J. McBride

Ethanol Drinking and Deprivation Alter Dopaminergic and Serotonergic Function in the Nucleus Accumbens of Alcohol-Preferring Rats
J Pharmacol Exp Ther 2004 309: 216-225. Published online January 12, 2004; 10.1124/jpet.103.059790 [Abstract] [Full Text] [PDF]  

Md Harunor Rashid, Makoto Inoue, Kazuo Toda, and Hiroshi Ueda

Loss of Peripheral Morphine Analgesia Contributes to the Reduced Effectiveness of Systemic Morphine in Neuropathic Pain
J Pharmacol Exp Ther 2004 309: 380-387. Published online January 12, 2004; 10.1124/jpet.103.060582 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Zachary S. Bowman, John E. Oatis, Jr., Jennifer L. Whelan, David J. Jollow, and David C. McMillan

Primaquine-Induced Hemolytic Anemia: Susceptibility of Normal versus Glutathione-Depleted Rat Erythrocytes to 5-Hydroxyprimaquine
J Pharmacol Exp Ther 2004 309: 79-85. Published online January 14, 2004; 10.1124/jpet.103.062984 [Abstract] [Full Text] [PDF]  

R. Michael Baldwin, William T. Jewell, Michelle V. Fanucchi, Charles G. Plopper, and Alan R. Buckpitt

Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque
J Pharmacol Exp Ther 2004 309: 127-136. Published online January 14, 2004; 10.1124/jpet.103.062901 [Abstract] [Full Text] [PDF]  

ERRATA:

Correction to "Sites of Excitatory and Inhibitory Actions of Alcohols on Neuronal 24 Nicotinic Acetylcholine Receptors"
J Pharmacol Exp Ther 2004 309: 439. [Full Text] [PDF]  

Correction to "Human Hepatic CYP2E1 Expression during Development"
J Pharmacol Exp Ther 2004 309: 439. [Full Text] [PDF]  

Correction to "Ca²⁺ Channel Blockers Enhance Neurotensin (NT) Binding and Inhibit NT-Induced Inositol Phosphate Formation in Prostate Cancer PC3 Cells"
J Pharmacol Exp Ther 2004 309: 439. [Full Text] [PDF]  

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