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Cover Caption
Other Issues:
July 2003; 306 (1)   [Index by Author]  [Cover Caption]
       PERSPECTIVES IN PHARMACOLOGY
       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
       BEHAVIORAL PHARMACOLOGY
       CARDIOVASCULAR
       CELLULAR AND MOLECULAR
       ENDOCRINE AND REPRODUCTIVE
       GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
       INFLAMMATION AND IMMUNOPHARMACOLOGY
       NEUROPHARMACOLOGY
       TOXICOLOGY
       ERRATA
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PERSPECTIVES IN PHARMACOLOGY:

Theodore A. Slotkin, J. Todd Auman, and Frederic J. Seidler
Ontogenesis of {beta}-Adrenoceptor Signaling: Implications for Perinatal Physiology and for Fetal Effects of Tocolytic Drugs
J Pharmacol Exp Ther 2003 306: 1-7. Published online April 7, 2003; 10.1124/jpet.102.048421 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Ryota Kikuchi, Hiroyuki Kusuhara, Daisuke Sugiyama, and Yuichi Sugiyama
Contribution of Organic Anion Transporter 3 (Slc22a8) to the Elimination of p-Aminohippuric Acid and Benzylpenicillin across the Blood-Brain Barrier
J Pharmacol Exp Ther 2003 306: 51-58. Published online April 8, 2003; 10.1124/jpet.103.049197 [Abstract] [Full Text] [PDF]  

Tatiana N. Nanovskaya, Sujal V. Deshmukh, Rachel Miles, Steve Burmaster, and Mahmoud S. Ahmed
Transfer of L-{alpha}-Acetylmethadol (LAAM) and L-{alpha}-Acetyl-N-normethadol (norLAAM) by the Perfused Human Placental Lobule
J Pharmacol Exp Ther 2003 306: 205-212. Published online April 3, 2003; 10.1124/jpet.103.050690 [Abstract] [Full Text] [PDF]  

Bryan A. Ward, J. Christopher Gorski, David R. Jones, Stephen D. Hall, David A. Flockhart, and Zeruesenay Desta
The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity
J Pharmacol Exp Ther 2003 306: 287-300. Published online April 3, 2003; 10.1124/jpet.103.049601 [Abstract] [Full Text] [PDF]  

Shigeki Tamura, Yuji Tokunaga, Rinta Ibuki, Gordon L. Amidon, Hitoshi Sezaki, and Shinji Yamashita
The Site-Specific Transport and Metabolism of Tacrolimus in Rat Small Intestine
J Pharmacol Exp Ther 2003 306: 310-316. Published online April 3, 2003; 10.1124/jpet.103.050716 [Abstract] [Full Text] [PDF]  

Rohini Ramakrishnan, Wing K. Cheung, Francis Farrell, Linda Joffee, and William J. Jusko
Pharmacokinetic and Pharmacodynamic Modeling of Recombinant Human Erythropoietin after Intravenous and Subcutaneous Dose Administration in Cynomolgus Monkeys
J Pharmacol Exp Ther 2003 306: 324-331. Published online April 3, 2003; 10.1124/jpet.102.047191 [Abstract] [Full Text] [PDF]  

Khadija Ouguerram, Thierry Magot, Yassine Zäir, J. S. Marchini, Bernard Charbonnel, Herve Laouenan, and Michel Krempf
Effect of Atorvastatin on Apolipoprotein B100 Containing Lipoprotein Metabolism in Type-2 Diabetes
J Pharmacol Exp Ther 2003 306: 332-337. Published online April 8, 2003; 10.1124/jpet.103.048991 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

M. Solinas, L. V. Panlilio, K. Antoniou, L. A. Pappas, and S. R. Goldberg
The Cannabinoid CB1 Antagonist N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) Differentially Alters the Reinforcing Effects of Heroin under Continuous Reinforcement, Fixed Ratio, and Progressive Ratio Schedules of Drug Self-Administration in Rats
J Pharmacol Exp Ther 2003 306: 93-102. Published online March 26, 2003; 10.1124/jpet.102.047928 [Abstract] [Full Text] [PDF]  

Gene G. Kinney, Maryann Burno, Una C. Campbell, Lisa M. Hernandez, Dana Rodriguez, Linda J. Bristow, and P. Jeffrey Conn
Metabotropic Glutamate Subtype 5 Receptors Modulate Locomotor Activity and Sensorimotor Gating in Rodents
J Pharmacol Exp Ther 2003 306: 116-123. Published online March 26, 2003; 10.1124/jpet.103.048702 [Abstract] [Full Text] [PDF]  

Craig R. Rush, William W. Stoops, Lon R. Hays, Paul E. A. Glaser, and Lon S. Hays
Risperidone Attenuates the Discriminative-Stimulus Effects of d-Amphetamine in Humans
J Pharmacol Exp Ther 2003 306: 195-204. Published online April 3, 2003; 10.1124/jpet.102.048439 [Abstract] [Full Text] [PDF]  

Hiroshi Nojima and E. Carstens
5-Hydroxytryptamine (5-HT)2 Receptor Involvement in Acute 5-HT-Evoked Scratching but Not in Allergic Pruritus Induced by Dinitrofluorobenzene in Rats
J Pharmacol Exp Ther 2003 306: 245-252. Published online April 7, 2003; 10.1124/jpet.103.049239 [Abstract] [Full Text] [PDF]  

J. S. Schneider, J. P. Tinker, F. Menzaghi, and G. K. Lloyd
The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys
J Pharmacol Exp Ther 2003 306: 401-406. Published online April 29, 2003; 10.1124/jpet.103.051912 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Hélène C. Seegers, Vivienne C. Hood, Bruce L. Kidd, Simon C. Cruwys, and David A. Walsh
Enhancement of Angiogenesis by Endogenous Substance P Release and Neurokinin-1 Receptors During Neurogenic Inflammation
J Pharmacol Exp Ther 2003 306: 8-12. Published online March 26, 2003; 10.1124/jpet.103.050013 [Abstract] [Full Text] [PDF]  

Robert D. Mayer, Xiaojun Wang, and Mahin D. Maines
Nitric Oxide Inhibitor N{omega}-Nitro-L-arginine Methyl Ester Potentiates Induction of Heme Oxygenase-1 in Kidney Ischemia/Reperfusion Model: A Novel Mechanism for Regulation of the Oxygenase
J Pharmacol Exp Ther 2003 306: 43-50. Published online April 3, 2003; 10.1124/jpet.102.048686 [Abstract] [Full Text] [PDF]  

S. Rolin, M. Petein, V. Tchana-Sato, J. M. Dogne, P. Benoit, B. Lambermont, A. Ghuysen, P. Kolh, and B. Masereel
BM-573, a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, Prevents Pig Myocardial Infarction Induced by Coronary Thrombosis
J Pharmacol Exp Ther 2003 306: 59-65. Published online April 29, 2003; 10.1124/jpet.102.046607 [Abstract] [Full Text] [PDF]  

Takuya Matsumoto, Livius V. d'uscio, Daihiko Eguchi, Masahiko Akiyama, Leslie A. Smith, and Zvonimir S. Katusic
Protective Effect of Chronic Vitamin C Treatment on Endothelial Function of Apolipoprotein E-Deficient Mouse Carotid Artery
J Pharmacol Exp Ther 2003 306: 103-108. Published online March 26, 2003; 10.1124/jpet.103.049163 [Abstract] [Full Text] [PDF]  

D. L. Lee, B. R. Wamhoff, L. C. Katwa, H. K. Reddy, D. J. Voelker, J. L. Dixon, and M. Sturek
Increased Endothelin-Induced Ca2+ Signaling, Tyrosine Phosphorylation, and Coronary Artery Disease in Diabetic Dyslipidemic Swine Are Prevented by Atorvastatin
J Pharmacol Exp Ther 2003 306: 132-140. Published online March 27, 2003; 10.1124/jpet.103.049577 [Abstract] [Full Text] [PDF]  

Gregory R. Ferrier and Susan E. Howlett
Differential Effects of Phosphodiesterase-Sensitive and -Resistant Analogs of cAMP on Initiation of Contraction in Cardiac Ventricular Myocytes
J Pharmacol Exp Ther 2003 306: 166-178. Published online March 28, 2003; 10.1124/jpet.103.049676 [Abstract] [Full Text] [PDF]  

Casilde Sesti, Motohiro Koyama, M. Johan Broekman, Aaron J. Marcus, and Roberto Levi
Ectonucleotidase in Sympathetic Nerve Endings Modulates ATP and Norepinephrine Exocytosis in Myocardial Ischemia
J Pharmacol Exp Ther 2003 306: 238-244. Published online April 3, 2003; 10.1124/jpet.103.049874 [Abstract] [Full Text] [PDF]  

Mahmoud M. El-Mas and Abdel A. Abdel-Rahman
Effects of Chronic Ethanol Feeding on Clonidine-Evoked Reductions in Blood Pressure, Heart Rate, and Their Variability: Time-Domain Analyses
J Pharmacol Exp Ther 2003 306: 271-278. Published online March 26, 2003; 10.1124/jpet.102.048355 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

A. Banan, A. Farhadi, J. Z. Fields, E. Mutlu, L. Zhang, and A. Keshavarzian
Evidence That Nuclear Factor-{kappa}B Activation Is Critical in Oxidant-Induced Disruption of the Microtubule Cytoskeleton and Barrier Integrity and That Its Inactivation Is Essential in Epidermal Growth Factor-Mediated Protection of the Monolayers of Intestinal Epithelia
J Pharmacol Exp Ther 2003 306: 13-28. Published online March 26, 2003; 10.1124/jpet.102.047415 [Abstract] [Full Text] [PDF] Correction  

Stephen Hsu, Wendy B. Bollag, Jill Lewis, Qin Huang, Baldev Singh, Mohamed Sharawy, Tetsuya Yamamoto, and George Schuster
Green Tea Polyphenols Induce Differentiation and Proliferation in Epidermal Keratinocytes
J Pharmacol Exp Ther 2003 306: 29-34. Published online March 27, 2003; 10.1124/jpet.103.049734 [Abstract] [Full Text] [PDF]  

Christoph H. Kindler, Matthias Paul, Hilary Zou, Canhui Liu, Bruce D. Winegar, Andrew T. Gray, and C. Spencer Yost
Amide Local Anesthetics Potently Inhibit the Human Tandem Pore Domain Background K+ Channel TASK-2 (KCNK5)
J Pharmacol Exp Ther 2003 306: 84-92. Published online March 26, 2003; 10.1124/jpet.103.049809 [Abstract] [Full Text] [PDF]  

Magnus M. Berglund, Douglas A. Schober, Michael A. Statnick, Patricia H. McDonald, and Donald R. Gehlert
The Use of Bioluminescence Resonance Energy Transfer 2 to Study Neuropeptide Y Receptor Agonist-Induced {beta}-Arrestin 2 Interaction
J Pharmacol Exp Ther 2003 306: 147-156. Published online March 28, 2003; 10.1124/jpet.103.051227 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND REPRODUCTIVE:

Rocco Cirillo, Enrico Gillio Tos, Matthias K. Schwarz, Anna Quattropani, Alexander Scheer, Marc Missotten, Jerôme Dorbais, Anthony Nichols, Francesco Borrelli, Claudio Giachetti, Lucia Golzio, Paolo Marinelli, Russell J. Thomas, Claude Chevillard, Florence Laurent, Karine Portet, Claude Barberis, and André Chollet
Pharmacology of (2S,4Z)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a New Potent and Selective Nonpeptide Antagonist of the Oxytocin Receptor
J Pharmacol Exp Ther 2003 306: 253-261. Published online March 26, 2003; 10.1124/jpet.103.049395 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Qi Cai, Natalia I. Dmitrieva, Luis F. Michea, Gerson Rocha, Douglas Ferguson, and Maurice B. Burg
Toxicity of Acetaminophen, Salicylic Acid, and Caffeine for First-Passage Rat Renal Inner Medullary Collecting Duct Cells
J Pharmacol Exp Ther 2003 306: 35-42. Published online March 27, 2003; 10.1124/jpet.102.047431 [Abstract] [Full Text] [PDF]  

Enrique J. Sánchez Pozzi, Fernando A. Crocenzi, José M. Pellegrino, Viviana A. Catania, Marcelo G. Luquita, Marcelo G. Roma, Emilio A. Rodríguez Garay, and Aldo D. Mottino
Ursodeoxycholate Reduces Ethinylestradiol Glucuronidation in the Rat: Role in Prevention of Estrogen-Induced Cholestasis
J Pharmacol Exp Ther 2003 306: 279-286. Published online March 27, 2003; 10.1124/jpet.103.049940 [Abstract] [Full Text] [PDF]  

Marie-Claude L'Heureux and Patricia L. Brubaker
Glucagon-Like Peptide-2 and Common Therapeutics in a Murine Model of Ulcerative Colitis
J Pharmacol Exp Ther 2003 306: 347-354. Published online July 1, 2003; 10.1124/jpet.103.051771 [Abstract] [Full Text] [PDF]  

Fátima Martel, Rosário Monteiro, and Clara Lemos
Uptake of Serotonin at the Apical and Basolateral Membranes of Human Intestinal Epithelial (Caco-2) Cells Occurs through the Neuronal Serotonin Transporter (SERT)
J Pharmacol Exp Ther 2003 306: 355-362. Published online April 7, 2003; 10.1124/jpet.103.049668 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Donald E. Mager, Berend Neuteboom, Constantinos Efthymiopoulos, Alain Munafo, and William J. Jusko
Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Interferon-{beta}1a in Monkeys
J Pharmacol Exp Ther 2003 306: 262-270. Published online March 26, 2003; 10.1124/jpet.103.049502 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Kazushige Ohno, Rie Tsutsumi, Naoyuki Matsumoto, Hiroshi Yamashita, Yoko Amada, Jun-Ichi Shishikura, Hiroshi Inami Shin-Ichi Yatsugi, Masamichi Okada, Shuichi Sakamoto, and Tokio Yamaguchi
Functional Characterization of YM928, a Novel Noncompetitive {alpha}-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist
J Pharmacol Exp Ther 2003 306: 66-72. Published online March 26, 2003; 10.1124/jpet.103.049973 [Abstract] [Full Text] [PDF]  

Jordi Riba, Marta Valle, Gloria Urbano, Mercedes Yritia, Adelaida Morte, and Manel J. Barbanoj
Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics
J Pharmacol Exp Ther 2003 306: 73-83. Published online March 26, 2003; 10.1124/jpet.103.049882 [Abstract] [Full Text] [PDF]  

Eva V. Varga, Marc K. Rubenzik, Dagmar Stropova, Masano Sugiyama, Vanessa Grife, Victor J. Hruby, Kenner C. Rice, William R. Roeske, and Henry I. Yamamura
Converging Protein Kinase Pathways Mediate Adenylyl Cyclase Superactivation upon Chronic {delta}-Opioid Agonist Treatment
J Pharmacol Exp Ther 2003 306: 109-115. Published online March 26, 2003; 10.1124/jpet.103.049643 [Abstract] [Full Text] [PDF]  

Heidrun Potschka, Maren Fedrowitz, and Wolfgang Löscher
Multidrug Resistance Protein MRP2 Contributes to Blood-Brain Barrier Function and Restricts Antiepileptic Drug Activity
J Pharmacol Exp Ther 2003 306: 124-131. Published online March 27, 2003; 10.1124/jpet.103.049858 [Abstract] [Full Text] [PDF]  

Makoto Inoue, Toshiko Kawashima, Richard G. Allen, and Hiroshi Ueda
Nocistatin and Prepro-Nociceptin/Orphanin FQ 160–187 Cause Nociception through Activation of Gi/o in Capsaicin-Sensitive and of Gs in Capsaicin-Insensitive Nociceptors, Respectively
J Pharmacol Exp Ther 2003 306: 141-146. Published online March 28, 2003; 10.1124/jpet.103.049361 [Abstract] [Full Text] [PDF]  

M. C. H. Ko, H. Lee, C. Harrison, M. J. Clark, H. F. Song, N. N. Naughton, J. H. Woods, and J. R. Traynor
Studies of µ-, {kappa}-, and {delta}-Opioid Receptor Density and G Protein Activation in the Cortex and Thalamus of Monkeys
J Pharmacol Exp Ther 2003 306: 179-186. Published online April 3, 2003; 10.1124/jpet.103.050625 [Abstract] [Full Text] [PDF]  

Akihiro Noda, Hiroyuki Takamatsu, Nobuya Matsuoka, Satoshi Koyama, Hideo Tsukada, and Shintaro Nishimura
Effect of N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate (FK960), an Antidementia Drug with a Novel Mechanism of Action, on Regional Cerebral Blood Flow and Glucose Metabolism in Aged Rhesus Macaques Studied with Positron Emission Tomography
J Pharmacol Exp Ther 2003 306: 213-217. Published online April 3, 2003; 10.1124/jpet.103.050245 [Abstract] [Full Text] [PDF]  

Heather C. Salzberg-Brenhouse, Er-Yun Chen, Dwaine F. Emerich, Sam Baldwin, Ken Hogeland, Sharon Ranelli, Denise Lafreniere, Brigido Perdomo, Leah Novak, Theodora Kladis, Karen Fu, Anthony S. Basile, Jeffrey H. Kordower, and Raymond T. Bartus
Inhibitors of Cyclooxygenase-2, but Not Cyclooxygenase-1 Provide Structural and Functional Protection against Quinolinic Acid-Induced Neurodegeneration
J Pharmacol Exp Ther 2003 306: 218-228. Published online April 3, 2003; 10.1124/jpet.103.049700 [Abstract] [Full Text] [PDF]  

Jesse A. May, Marsha A. McLaughlin, Najam A. Sharif, Mark R. Hellberg, and Thomas R. Dean
Evaluation of the Ocular Hypotensive Response of Serotonin 5-HT1A and 5-HT2 Receptor Ligands in Conscious Ocular Hypertensive Cynomolgus Monkeys
J Pharmacol Exp Ther 2003 306: 301-309. Published online April 3, 2003; 10.1124/jpet.103.049528 [Abstract] [Full Text] [PDF]  

G. J. Rodríguez, D. L. Roman, K. J. White, D. E. Nichols, and E. L. Barker
Distinct Recognition of Substrates by the Human and Drosophila Serotonin Transporters
J Pharmacol Exp Ther 2003 306: 338-346. Published online April 7, 2003; 10.1124/jpet.103.048751 [Abstract] [Full Text] [PDF]  

Stefania Ruiu, Gèrard A. Pinna, Giorgio Marchese, Jean-Mario Mussinu, Pierluigi Saba, Simone Tambaro, Paola Casti, Romina Vargiu, and Luca Pani
Synthesis and Characterization of NESS 0327: A Novel Putative Antagonist of the CB1 Cannabinoid Receptor
J Pharmacol Exp Ther 2003 306: 363-370. Published online March 27, 2003; 10.1124/jpet.103.049924 [Abstract] [Full Text] [PDF]  

Christophe Rousselle, Philippe Clair, Maria Smirnova, Yuri Kolesnikov, Gavril W. Pasternak, Stéphanie Gac-Breton, Anthony R. Rees, Jean-Michel Scherrmann, and Jamal Temsamani
Improved Brain Uptake and Pharmacological Activity of Dalargin Using a Peptide-Vector-Mediated Strategy
J Pharmacol Exp Ther 2003 306: 371-376. Published online April 7, 2003; 10.1124/jpet.102.048520 [Abstract] [Full Text] [PDF]  

Kenneth J. Valenzano, Elfrida R. Grant, Gang Wu, Mohamed Hachicha, Lori Schmid, Laykea Tafesse, Qun Sun, Yakov Rotshteyn, Joseph Francis, James Limberis, Shiazah Malik, Edward R. Whittemore, and Dianne Hodges
N-(4-Tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: I. In Vitro Characterization and Pharmacokinetic Properties
J Pharmacol Exp Ther 2003 306: 377-386. Published online April 29, 2003; 10.1124/jpet.102.045674 [Abstract] [Full Text] [PDF]  

James D. Pomonis, James E. Harrison, Lilly Mark, David R. Bristol, Kenneth J. Valenzano, and Katharine Walker
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: II. In Vivo Characterization in Rat Models of Inflammatory and Neuropathic Pain
J Pharmacol Exp Ther 2003 306: 387-393. Published online April 29, 2003; 10.1124/jpet.102.046268 [Abstract] [Full Text] [PDF]  

Hirokazu Mizoguchi, Amanda Spaulding, Randy Leitermann, Hsiang-En Wu, Hiroshi Nagase, and Leon F. Tseng
Buprenorphine Blocks {epsilon}- and µ-Opioid Receptor-Mediated Antinociception in the Mouse
J Pharmacol Exp Ther 2003 306: 394-400. Published online April 29, 2003; 10.1124/jpet.103.048835 [Abstract] [Full Text] [PDF]  

C. Cohen, O. E. Bergis, F. Galli, A. W. Lochead, S. Jegham, B. Biton, J. Léonardon, P. Avenet, F. Sgard, F. Besnard, D. Graham, A. Coste, A. Oblin, O. Curet, C. Voltz, A. Gardes, D. Caille, G. Perrault, P. George, P. Soubrié, and B. Scatton
SSR591813, a Novel Selective and Partial {alpha}4{beta}2 Nicotinic Receptor Agonist with Potential as an Aid to Smoking Cessation
J Pharmacol Exp Ther 2003 306: 407-420. Published online April 7, 2003; 10.1124/jpet.103.049262 [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Grazyna Nowak
Protein Kinase C Mediates Repair of Mitochondrial and Transport Functions after Toxicant-Induced Injury in Renal Cells
J Pharmacol Exp Ther 2003 306: 157-165. Published online March 28, 2003; 10.1124/jpet.103.050336 [Abstract] [Full Text] [PDF]  

Teri Wadsworth, Hataya Poonyagariyagorn, Elinore Sullivan, Dennis Koop, and Charles E. Roselli
In Vivo Effect of PC-SPES on Prostate Growth and Hepatic CYP3A Expression in Rats
J Pharmacol Exp Ther 2003 306: 187-194. Published online April 3, 2003; 10.1124/jpet.102.048645 [Abstract] [Full Text] [PDF]  

John Farrell, Dean J. Naisbitt, Nicola S. Drummond, Jan P. H. Depta, F. Javier Vilar, Munir Pirmohamed, and B. Kevin Park
Characterization of Sulfamethoxazole and Sulfamethoxazole Metabolite-Specific T-Cell Responses in Animals and Humans
J Pharmacol Exp Ther 2003 306: 229-237. Published online April 3, 2003; 10.1124/jpet.103.050112 [Abstract] [Full Text] [PDF]  

Kyoji Morita, Hideki Arimochi, and Yoshinari Ohnishi
In Vitro Cytotoxicity of 4-Methylcatechol in Murine Tumor Cells: Induction of Apoptotic Cell Death by Extracellular Pro-Oxidant Action
J Pharmacol Exp Ther 2003 306: 317-323. Published online April 3, 2003; 10.1124/jpet.103.050351 [Abstract] [Full Text] [PDF]  

ERRATA:

Correction to "Nitric Oxide-Donating Nonsteroidal Anti-Inflammatory Drugs Inhibit the Growth of Various Cultured Human Cancer Cells: Evidence of a Tissue Type-Independent Effect"
J Pharmacol Exp Ther 2003 306: 421. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Schematic example of stimulatory and inhibitory receptor mechanisms controlling adenylyl cyclase (AC) activity in developing rat cardiac cells. See the article by Slotkin et al. on page 1 of this issue.


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