JPET -- Table of Contents (300 [1])

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):
Year:		Vol:		Page:

Receive this page by email each issue: [Sign up for eTOCs]

Other Issues:
January 2002; 300 (1)   [Index by Author] [Cover Caption]

       PERSPECTIVES IN PHARMACOLOGY

       ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

       CARDIOVASCULAR

       CELLULAR AND MOLECULAR

       CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

       INFLAMMATION AND IMMUNOPHARMACOLOGY

       NEUROPHARMACOLOGY

       TOXICOLOGY

Find articles in this issue containing these words:
[Search ALL Issues]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

PERSPECTIVES IN PHARMACOLOGY:

H. Möhler, J. M. Fritschy, and U. Rudolph: A New Benzodiazepine Pharmacology
J Pharmacol Exp Ther 2002 300: 2-8. [Abstract] [Full Text] [PDF]

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Tatiana Nanovskaya, Sujal Deshmukh, Monica Brooks, and Mahmoud S. Ahmed: Transplacental Transfer and Metabolism of Buprenorphine
J Pharmacol Exp Ther 2002 300: 26-33. [Abstract] [Full Text] [PDF]

Zhao-Qian Liu, Bing Zhu, Yun-Fu Tan, Zhi-Rong Tan, Lian-Sheng Wang, Song-Lin Huang, Yan Shu, and Hong-Hao Zhou: O-Dealkylation of Fluoxetine in Relation to CYP2C19 Gene Dose and Involvement of CYP3A4 in Human Liver Microsomes
J Pharmacol Exp Ther 2002 300: 105-111. [Abstract] [Full Text] [PDF]

Grace L. Guo, Supratim Choudhuri, and Curtis D. Klaassen: Induction Profile of Rat Organic Anion Transporting Polypeptide 2 (oatp2) by Prototypical Drug-Metabolizing Enzyme Inducers That Activate Gene Expression through Ligand-Activated Transcription Factor Pathways
J Pharmacol Exp Ther 2002 300: 206-212. [Abstract] [Full Text] [PDF]

Takanori Hashizume, Susumu Imaoka, Masashi Mise, Yoshiaki Terauchi, Toshihiko Fujii, Hisashi Miyazaki, Tetsuya Kamataki, and Yoshihiko Funae: Involvement of CYP2J2 and CYP4F12 in the Metabolism of Ebastine in Human Intestinal Microsomes
J Pharmacol Exp Ther 2002 300: 298-304. [Abstract] [Full Text] [PDF]

R. T. Meijer, R. P. Koopmans, I. J. M. ten Berge, and P. T. A. Schellekens: Pharmacokinetics of Murine Anti-Human CD3 Antibodies in Man Are Determined by the Disappearance of Target Antigen
J Pharmacol Exp Ther 2002 300: 346-353. [Abstract] [Full Text] [PDF]

CARDIOVASCULAR:

Mostafa Khalid, Norelyaquine Ilhami, Yves Giudicelli, and Jean-Pierre Dausse: Testosterone Dependence of Salt-Induced Hypertension in Sabra Rats and Role of Renal $alpha$ ₂-Adrenoceptor Subtypes
J Pharmacol Exp Ther 2002 300: 43-49. [Abstract] [Full Text] [PDF]

Priya Venkatesan, Jijiang Wang, Cory Evans, Mustapha Irnaten, and David Mendelowitz: Nociceptin Inhibits $gamma$ -Aminobutyric Acidergic Inputs to Cardiac Parasympathetic Neurons in the Nucleus Ambiguus
J Pharmacol Exp Ther 2002 300: 78-82. [Abstract] [Full Text] [PDF]

Alain Deschamps, Steven B. Backman, Vera Novak, Gilles Plourde, Pierre Fiset, and Daniel Chartrand: Effects of the Anticholinesterase Edrophonium on Spectral Analysis of Heart Rate and Blood Pressure Variability in Humans
J Pharmacol Exp Ther 2002 300: 112-117. [Abstract] [Full Text] [PDF]

C. W. Schindler, J. P. Gilman, J. Bergman, N. K. Mello, R. L. Woosley, and S. R. Goldberg: Interactions between Cocaine and Dopamine Agonists on Cardiovascular Function in Squirrel Monkeys
J Pharmacol Exp Ther 2002 300: 180-187. [Abstract] [Full Text] [PDF]

Asifa Haider, Rafal Olszanecki, Richard Gryglewski, Michal L. Schwartzman, Elias Lianos, Attallah Kappas, Alberto Nasjletti, and Nader G. Abraham: Regulation of Cyclooxygenase by the Heme-Heme Oxygenase System in Microvessel Endothelial Cells
J Pharmacol Exp Ther 2002 300: 188-194. [Abstract] [Full Text] [PDF]

Chih-Chang Wei, Carlos M. Ferrario, K. Bridget Brosnihan, Diane M. Farrell, Wayne E. Bradley, Ayad A. Jaffa, and Louis J. Dell'Italia: Angiotensin Peptides Modulate Bradykinin Levels in the Interstitium of the Dog Heart in Vivo
J Pharmacol Exp Ther 2002 300: 324-329. [Abstract] [Full Text] [PDF]

CELLULAR AND MOLECULAR:

Elfrida R. Grant, Adrienne E. Dubin, Sui-Po Zhang, Robert A. Zivin, and Zhong Zhong: Simultaneous Intracellular Calcium and Sodium Flux Imaging in Human Vanilloid Receptor 1 (VR1)-Transfected Human Embryonic Kidney Cells: A Method to Resolve Ionic Dependence of VR1-Mediated Cell Death
J Pharmacol Exp Ther 2002 300: 9-17. [Abstract] [Full Text] [PDF]

Gerald F. Davies, Pamela J. McFie, Ramji L. Khandelwal, and William J. Roesler: Unique Ability of Troglitazone to Up-Regulate Peroxisome Proliferator-Activated Receptor- $gamma$ Expression in Hepatocytes
J Pharmacol Exp Ther 2002 300: 72-77. [Abstract] [Full Text] [PDF]

Bruce A. Waldrop, Diana Mastalerz, Michael T. Piascik, and Ginell R. Post: $alpha$ _1B- and $alpha$ _1D-Adrenergic Receptors Exhibit Different Requirements for Agonist and Mitogen-Activated Protein Kinase Activation to Regulate Growth Responses in Rat 1 Fibroblasts
J Pharmacol Exp Ther 2002 300: 83-90. [Abstract] [Full Text] [PDF]

Jiefa Wang, Lei Wang, Jodi L. Anderson, Nancy A. Schulte, and Myron L. Toews: Regulatory Properties of $alpha$ _1B-Adrenergic Receptors Defective in Coupling to Phosphoinositide Hydrolysis
J Pharmacol Exp Ther 2002 300: 134-141. [Abstract] [Full Text] [PDF]

John R. Traynor, Mary J. Clark, and Ann E. Remmers: Relationship between Rate and Extent of G Protein Activation: Comparison between Full and Partial Opioid Agonists
J Pharmacol Exp Ther 2002 300: 157-161. [Abstract] [Full Text] [PDF]

William E. Courchesne: Characterization of a Novel, Broad-Based Fungicidal Activity for the Antiarrhythmic Drug Amiodarone
J Pharmacol Exp Ther 2002 300: 195-199. [Abstract] [Full Text] [PDF]

Douglas W. P. Hay, Giuseppe A. M. Giardina, Don E. Griswold, David C. Underwood, Charles J. Kotzer, Brian Bush, William Potts, Punam Sandhu, Dave Lundberg, James J. Foley, Dulcie B. Schmidt, Lenox D. Martin, David Kilian, Jeffrey J. Legos, Frank C. Barone, Mark A. Luttmann, Mario Grugni, Luca F. Raveglia, and Henry M. Sarau: Nonpeptide Tachykinin Receptor Antagonists. III. SB 235375, a Low Central Nervous System-Penetrant, Potent and Selective Neurokinin-3 Receptor Antagonist, Inhibits Citric Acid-Induced Cough and Airways Hyper-reactivity in Guinea Pigs
J Pharmacol Exp Ther 2002 300: 314-323. [Abstract] [Full Text] [PDF]

Hung Wu, Huang-Wei Shen, Tin-Feng Wu, Lawrence F. Brass, and Kuo-Chun Sung: Extracellular Signal-Regulated Kinases and G Protein-Coupled Receptors in Megakaryocytic Human Erythroleukemia Cells: Selective Activation, Differential Regulation, and Dissociation from Mitogenesis
J Pharmacol Exp Ther 2002 300: 339-345. [Abstract] [Full Text] [PDF]

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Christopher A. Warlick, Michaeleen D. Diers, John E. Wagner, and R. Scott McIvor: In Vivo Selection of Antifolate-Resistant Transgenic Hematopoietic Stem Cells in a Murine Bone Marrow Transplant Model
J Pharmacol Exp Ther 2002 300: 50-56. [Abstract] [Full Text] [PDF]

Patrizia Russo, Cristina Ottoboni, Davide Malacarne, Alessandra Crippa, Jean-Francois Riou, and Patrick M. O'Connor: Nonpeptidomimetic Farnesyltransferase Inhibitor RPR-115135 Increases Cytotoxicity of 5-Fluorouracil: Role of p53
J Pharmacol Exp Ther 2002 300: 220-226. [Abstract] [Full Text] [PDF]

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Liping Zhang, Ying Lu, Ying Chen, and Karin N. Westlund: Group I Metabotropic Glutamate Receptor Antagonists Block Secondary Thermal Hyperalgesia in Rats with Knee Joint Inflammation
J Pharmacol Exp Ther 2002 300: 149-156. [Abstract] [Full Text] [PDF]

Tohru Noji, Makoto Takayama, Mirai Mizutani, Yuko Okamura, Haruki Takai, Akira Karasawa, and Hideaki Kusaka: KF24345, an Adenosine Uptake Inhibitor, Suppresses Lipopolysaccharide-Induced Tumor Necrosis Factor- $alpha$ Production and Leukopenia via Endogenous Adenosine in Mice
J Pharmacol Exp Ther 2002 300: 200-205. [Abstract] [Full Text] [PDF]

Hideo Kohka Takahashi, Atsushi Yoshida, Hiromi Iwagaki, Tadashi Yoshino, Hideyuki Itoh, Toshihiko Morichika, Minori Yokoyama, Tadaatsu Akagi, Noriaki Tanaka, Shuji Mori, and Masahiro Nishibori: Histamine Regulation of Interleukin-18-Initiating Cytokine Cascade Is Associated with Down-Regulation of Intercellular Adhesion Molecule-1 Expression in Human Peripheral Blood Mononuclear Cells
J Pharmacol Exp Ther 2002 300: 227-235. [Abstract] [Full Text] [PDF]

Rohini Ramakrishnan, Debra C. DuBois, Richard R. Almon, Nancy A. Pyszczynski, and William J. Jusko: Pharmacodynamics and Pharmacogenomics of Methylprednisolone during 7-Day Infusions in Rats
J Pharmacol Exp Ther 2002 300: 245-256. [Abstract] [Full Text] [PDF]

NEUROPHARMACOLOGY:

Nissar A. Darmani: The Potent Emetogenic Effects of the Endocannabinoid, 2-AG (2-Arachidonoylglycerol) Are Blocked by $Delta$ ⁹-Tetrahydrocannabinol and Other Cannnabinoids
J Pharmacol Exp Ther 2002 300: 34-42. [Abstract] [Full Text] [PDF]

Daniela Rizzi, Anna Rizzi, Raffaella Bigoni, Valeria Camarda, Giuliano Marzola, Remo Guerrini, Carmela De Risi, Domenico Regoli, and Girolamo Calo': [Arg¹⁴,Lys¹⁵]Nociceptin, a Highly Potent Agonist of the Nociceptin/Orphanin FQ Receptor: in Vitro and in Vivo Studies
J Pharmacol Exp Ther 2002 300: 57-63. [Abstract] [Full Text] [PDF]

Lars Eckardt, Günter Breithardt, and Wilhelm Haverkamp: Electrophysiologic Characterization of the Antipsychotic Drug Sertindole in a Rabbit Heart Model of Torsade de Pointes: Low Torsadogenic Potential Despite QT Prolongation
J Pharmacol Exp Ther 2002 300: 64-71. [Abstract] [Full Text] [PDF]

Chun-Su Yuan, Gang Wei, Joseph F. Foss, Michael O'Connor, Theodore Karrison, and Joachim Osinski: Effects of Subcutaneous Methylnaltrexone on Morphine-Induced Peripherally Mediated Side Effects: A Double-Blind Randomized Placebo-Controlled Trial
J Pharmacol Exp Ther 2002 300: 118-123. [Abstract] [Full Text] [PDF]

Zheng-Xiong Xi, David A. Baker, Hui Shen, Daniel S. Carson, and Peter W. Kalivas: Group II Metabotropic Glutamate Receptors Modulate Extracellular Glutamate in the Nucleus Accumbens
J Pharmacol Exp Ther 2002 300: 162-171. [Abstract] [Full Text] [PDF]

Maryellen Fazen Eckenhoff, Kin Chan, and Roderic G. Eckenhoff: Multiple Specific Binding Targets for Inhaled Anesthetics in the Mammalian Brain
J Pharmacol Exp Ther 2002 300: 172-179. [Abstract] [Full Text] [PDF]

Richard A. Houghtling and Barbara M. Bayer: Rapid Elevation of Plasma Interleukin-6 by Morphine Is Dependent on Autonomic Stimulation of Adrenal Gland
J Pharmacol Exp Ther 2002 300: 213-219. [Abstract] [Full Text] [PDF]

Cándido Hernández-López, Magí Farré, Pere N. Roset, Esther Menoyo, Nieves Pizarro, Jordi Ortuño, Marta Torrens, Jordi Camí, and Rafael de la Torre: 3,4-Methylenedioxymethamphetamine (Ecstasy) and Alcohol Interactions in Humans: Psychomotor Performance, Subjective Effects, and Pharmacokinetics
J Pharmacol Exp Ther 2002 300: 236-244. [Abstract] [Full Text] [PDF]

Grace C. Rossi, Michael Pellegrino, Randi Shane, Catherine A. Abbadie, Jessica Dustman, Charles Jimenez, Richard J. Bodnar, Gavril W. Pasternak, and Richard G. Allen: Characterization of Rat Prepro-Orphanin FQ/Nociceptin_(154-181): Nociceptive Processing in Supraspinal Sites
J Pharmacol Exp Ther 2002 300: 257-264. [Abstract] [Full Text] [PDF]

Pal Riba, Yong Ben, Andrew P. Smith, Susanna Furst, and Nancy M. Lee: Morphine Tolerance in Spinal Cord Is Due to Interaction between µ- and $delta$ -Receptors
J Pharmacol Exp Ther 2002 300: 265-272. [Abstract] [Full Text] [PDF]

Carolyn A. Fairbanks, Laura S. Stone, Kelley F. Kitto, H. Oanh Nguyen, Ivan J. Posthumus, and George L. Wilcox: $alpha$ _2C-Adrenergic Receptors Mediate Spinal Analgesia and Adrenergic-Opioid Synergy
J Pharmacol Exp Ther 2002 300: 282-290. [Abstract] [Full Text] [PDF]

J. Pintor, A. Peral, C. H. V. Hoyle, C. Redick, J. Douglass, I. Sims, and B. Yerxa: Effects of Diadenosine Polyphosphates on Tear Secretion in New Zealand White Rabbits
J Pharmacol Exp Ther 2002 300: 291-297. [Abstract] [Full Text] [PDF]

Douglas J. Pettibone, J. Fred Hess, Patricia J. Hey, Marlene A. Jacobson, Michael Leviten, Edward V. Lis, Pierre J. Mallorga, Danette M. Pascarella, Melissa A. Snyder, Jacinta B. Williams, and Zhizhen Zeng: The Effects of Deleting the Mouse Neurotensin Receptor NTR1 on Central and Peripheral Responses to Neurotensin
J Pharmacol Exp Ther 2002 300: 305-313. [Abstract] [Full Text] [PDF]

Klaas P. Zuideveld, Nicoline Treijtel, Hugo J. Maas, Josy M. Gubbens-Stibbe, Lambertus A. Peletier, Piet H. van der Graaf, and Meindert Danhof: A Competitive Interaction Model Predicts the Effect of WAY-100,635 on the Time Course of R-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin-Induced Hypothermia
J Pharmacol Exp Ther 2002 300: 330-338. [Abstract] [Full Text] [PDF]

TOXICOLOGY:

Jie Liu, Joseph E. Saavedra, Tong Lu, Jian-Guo Song, James Clark, Michael P. Waalkes, and Larry K. Keefer: O²-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate Protection Against D-Galactosamine/Endotoxin-Induced Hepatotoxicity in Mice: Genomic Analysis Using Microarrays
J Pharmacol Exp Ther 2002 300: 18-25. [Abstract] [Full Text] [PDF]

Robert G. Pendleton, Feroz Parvez, Marwa Sayed, and Ralph Hillman: Effects of Pharmacological Agents upon a Transgenic Model of Parkinson's Disease in Drosophila melanogaster
J Pharmacol Exp Ther 2002 300: 91-96. [Abstract] [Full Text] [PDF]

Nathan J. Cherrington, Dylan P. Hartley, Ning Li, David R. Johnson, and Curtis D. Klaassen: Organ Distribution of Multidrug Resistance Proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and Hepatic Induction of Mrp3 by Constitutive Androstane Receptor Activators in Rats
J Pharmacol Exp Ther 2002 300: 97-104. [Abstract] [Full Text] [PDF]

Tara Sankar Roy, Frederic J. Seidler, and Theodore A. Slotkin: Prenatal Nicotine Exposure Evokes Alterations of Cell Structure in Hippocampus and Somatosensory Cortex
J Pharmacol Exp Ther 2002 300: 124-133. [Abstract] [Full Text] [PDF]

Danyelle M. Townsend and Marie H. Hanigan: Inhibition of $gamma$ -Glutamyl Transpeptidase or Cysteine S-Conjugate $beta$ -Lyase Activity Blocks the Nephrotoxicity of Cisplatin in Mice
J Pharmacol Exp Ther 2002 300: 142-148. [Abstract] [Full Text] [PDF]

James V. Bruckner, Raghupathy Ramanathan, K. Monica Lee, and Srinivasa Muralidhara: Mechanisms of Circadian Rhythmicity of Carbon Tetrachloride Hepatotoxicity
J Pharmacol Exp Ther 2002 300: 273-281. [Abstract] [Full Text] [PDF]

Cover Caption:

The four classes of diazepam-sensitive GABA_A are distinguished by the type of $alpha$ -subunit. See the article by Möhler et al.on page 2 of thisissue.