PERSPECTIVES IN PHARMACOLOGY:

Warren Davis, Jr., Ze'ev Ronai, and Kenneth D. Tew

Cellular Thiols and Reactive Oxygen Species in Drug-Induced Apoptosis
J Pharmacol Exp Ther 2001 296: 1-6. [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

Akira Yamamoto, Hiroyuki Tatsumi, Masato Maruyama, Tomomi Uchiyama, Naoki Okada, and Takuya Fujita

Modulation of Intestinal Permeability by Nitric Oxide Donors: Implications in Intestinal Delivery of Poorly Absorbable Drugs
J Pharmacol Exp Ther 2001 296: 84-90. [Abstract] [Full Text] [PDF]  

Dietmar Schwab, Andreas W. Herling, Horst Hemmerle, Gerrit Schubert, Bruno Hagenbuch, and Hans-Joerg Burger

Hepatic Uptake of Synthetic Chlorogenic Acid Derivatives by the Organic Anion Transport Proteins
J Pharmacol Exp Ther 2001 296: 91-98. [Abstract] [Full Text] [PDF]  

Zohar Nachum, Baruch Shahal, Avi Shupak, Orna Spitzer, Adi Gonen, Itzchak Beiran, Haim Lavon, Mirit Eynan, Shlomit Dachir, and Aharon Levy

Scopolamine Bioavailability in Combined Oral and Transdermal Delivery
J Pharmacol Exp Ther 2001 296: 121-123. [Abstract] [Full Text] [PDF]  

Christophe Rousselle, Maria Smirnova, Philippe Clair, Jeanne-Marie Lefauconnier, Alain Chavanieu, Bernard Calas, Jean-Michel Scherrmann, and Jamal Temsamani

Enhanced Delivery of Doxorubicin into the Brain via a Peptide-Vector-Mediated Strategy: Saturation Kinetics and Specificity
J Pharmacol Exp Ther 2001 296: 124-131. [Abstract] [Full Text] [PDF]  

MeeRa Hong, Lyanne Schlichter, and Reina Bendayan

A Novel Zidovudine Uptake System in Microglia
J Pharmacol Exp Ther 2001 296: 141-149. [Abstract] [Full Text] [PDF]  

Phillip M. Gerk, Cheah Y. Oo, Earl W. Paxton, Jeffrey A. Moscow, and Patrick J. McNamara

Interactions between Cimetidine, Nitrofurantoin, and Probenecid Active Transport into Rat Milk
J Pharmacol Exp Ther 2001 296: 175-180. [Abstract] [Full Text] [PDF]  

Theunis C. Goosen, Danielle E. Mills, and Paul F. Hollenberg

Effects of Benzyl Isothiocyanate on Rat and Human Cytochromes P450: Identification of Metabolites Formed by P450 2B1
J Pharmacol Exp Ther 2001 296: 198-206. [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Thomas A. Morinelli, Jerry G. Webb, Ayad A. Jaffa, Philip J. Privitera, and Harry S. Margolius

A Metabolic Fragment of Bradykinin, Arg-Pro-Pro-Gly-Phe, Protects against the Deleterious Effects of Lipopolysaccharide in Rats
J Pharmacol Exp Ther 2001 296: 71-76. [Abstract] [Full Text] [PDF]  

Neal J. Thomas, Joseph A. Carcillo, William A. Herzer, Zaichuan Mi, and Edwin K. Jackson

Chronic Type IV Phosphodiesterase Inhibition Protects Glomerular Filtration Rate and Renal and Mesenteric Blood Flow in a Zymosan-Induced Model of Multiple Organ Dysfunction Syndrome Treated with Norepinephrine
J Pharmacol Exp Ther 2001 296: 168-174. [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Frank M. Dautzenberg, Gabrielle Py-Lang, Jacqueline Higelin, Christophe Fischer, Matthew B. Wright, and Gerda Huber

Different Binding Modes of Amphibian and Human Corticotropin-Releasing Factor Type 1 and Type 2 Receptors: Evidence for Evolutionary Differences
J Pharmacol Exp Ther 2001 296: 113-120. [Abstract] [Full Text] [PDF]  

Shizuo Yamada, Takashi Okura, and Ryohei Kimura

In Vivo Demonstration of _1A-Adrenoceptor Subtype Selectivity of KMD-3213 in Rat Tissues
J Pharmacol Exp Ther 2001 296: 160-167. [Abstract] [Full Text] [PDF]  

John E. Donello, Edwin U. Padillo, Michelle L. Webster, Larry A. Wheeler, and Daniel W. Gil

₂-Adrenoceptor Agonists Inhibit Vitreal Glutamate and Aspartate Accumulation and Preserve Retinal Function after Transient Ischemia
J Pharmacol Exp Ther 2001 296: 216-223. [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Margaret M. Mc Gee, Giuseppe Campiani, Anna Ramunno, Caterina Fattorusso, Vito Nacci, Mark Lawler, D. Clive Williams, and Daniela M. Zisterer

Pyrrolo-1,5-benzoxazepines Induce Apoptosis in Chronic Myelogenous Leukemia (CML) Cells by Bypassing the Apoptotic Suppressor Bcr-Abl
J Pharmacol Exp Ther 2001 296: 31-40. [Abstract] [Full Text] [PDF]  

ENDOCRINE AND REPRODUCTIVE:

Suzuko Hashiguchi, Toshihiko Yada, and Terukatsu Arima

A New Hypoglycemic Agent, JTT-608, Evokes Protein Kinase A-Mediated Ca²⁺ Signaling in Rat Islet -Cells: Strict Regulation by Glucose, Link to Insulin Release, and Cooperation with Glucagon-Like Peptide-1(7-36)amide and Pituitary Adenylate Cyclase-Activating Polypeptide
J Pharmacol Exp Ther 2001 296: 22-30. [Abstract] [Full Text] [PDF]  

Shiyao Xu, Bao Ting Zhu, and Allan H. Conney

Stimulatory Effect of Clofibrate and Gemfibrozil Administration on the Formation of Fatty Acid Esters of Estradiol by Rat Liver Microsomes
J Pharmacol Exp Ther 2001 296: 188-197. [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Satoru Takahashi, Yoshihiro Keto, Takuya Fujita, Tomomi Uchiyama, and Akira Yamamoto

FR167653, a p38 Mitogen-Activated Protein Kinase Inhibitor, Prevents Helicobacter pylori-Induced Gastritis in Mongolian Gerbils
J Pharmacol Exp Ther 2001 296: 48-56. [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Jodie J. Rady, William B. Campbell, and James M. Fujimoto

Antianalgesic Action of Nociceptin Originating in the Brain Is Mediated by Spinal Prostaglandin E₂ in Mice
J Pharmacol Exp Ther 2001 296: 7-14. [Abstract] [Full Text] [PDF]  

Britta Siegmund, Florian Rieder, Stefan Albrich, Katrin Wolf, Christoph Bidlingmaier, Gary S. Firestein, David Boyle, Hans-Anton Lehr, Florian Loher, Gunther Hartmann, Stefan Endres, and Andreas Eigler

Adenosine Kinase Inhibitor GP515 Improves Experimental Colitis in Mice
J Pharmacol Exp Ther 2001 296: 99-105. [Abstract] [Full Text] [PDF]  

Yoshihisa Saso, Elaine M. Conner, Bradley R. Teegarden, and Chong-Sheng Yuan

S-Adenosyl-L-homocysteine Hydrolase Inhibitor Mediates Immunosuppressive Effects in Vivo: Suppression of Delayed Type Hypersensitivity Ear Swelling and Peptidoglycan Polysaccharide-Induced Arthritis
J Pharmacol Exp Ther 2001 296: 106-112. [Abstract] [Full Text] [PDF]  

Angeliki Xagorari, Andreas Papapetropoulos, Antonis Mauromatis, Michalis Economou, Theodore Fotsis, and Charis Roussos

Luteolin Inhibits an Endotoxin-Stimulated Phosphorylation Cascade and Proinflammatory Cytokine Production in Macrophages
J Pharmacol Exp Ther 2001 296: 181-187. [Abstract] [Full Text] [PDF]  

Roberta Pacifici, Piergiorgio Zuccaro, Candido Hernández López, Simona Pichini, Simonetta Di Carlo, Magi Farré, Pere Nolasc Roset, Jordi Ortuño, Jordi Segura, and Rafael de La Torre

Acute Effects of 3,4-Methylenedioxymethamphetamine Alone and in Combination with Ethanol on the Immune System in Humans
J Pharmacol Exp Ther 2001 296: 207-215. [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Carol R. Sterling and A. William Tank

Adrenal Tyrosine Hydroxylase Activity and Gene Expression Are Increased by Intraventricular Administration of Nicotine
J Pharmacol Exp Ther 2001 296: 15-21. [Abstract] [Full Text] [PDF]  

Vilen A. Movsesyan, Deirdre M. O'Leary, Lei Fan, Weili Bao, Paul G. M. Mullins, Susan M. Knoblach, and Alan I. Faden

mGluR5 Antagonists 2-Methyl-6-(phenylethynyl)-pyridine and (E)-2-Methyl-6-(2-phenylethenyl)-pyridine Reduce Traumatic Neuronal Injury In Vitro and In Vivo by Antagonizing N-Methyl-D-aspartate Receptors
J Pharmacol Exp Ther 2001 296: 41-47. [Abstract] [Full Text] [PDF]  

Liana Beni-Adani, Illana Gozes, Yoram Cohen, Yaniv Assaf, Ruth A. Steingart, Douglas E. Brenneman, Oded Eizenberg, Victoria Trembolver, and Esther Shohami

A Peptide Derived from Activity-Dependent Neuroprotective Protein (ADNP) Ameliorates Injury Response in Closed Head Injury in Mice
J Pharmacol Exp Ther 2001 296: 57-63. [Abstract] [Full Text] [PDF]  

Svetlana Mihaylova-Todorova, Latchezar D. Todorov, and David P. Westfall

Correlation between the Release of the Sympathetic Neurotransmitter ATP and Soluble Nucleotidases from the Guinea Pig Vas Deferens
J Pharmacol Exp Ther 2001 296: 64-70. [Abstract] [Full Text] [PDF]  

Jiang Hong Ye, Liang Tao, Jun Ren, Rebecca Schaefer, Philip L. Liu, Dolores A. Schiller, and Joseph J. McArdle

Ethanol Potentiation of Glycine-Induced Responses in Dissociated Neurons of Rat Ventral Tegmental Area
J Pharmacol Exp Ther 2001 296: 77-83. [Abstract] [Full Text] [PDF]  

M. Imad Damaj

Influence of Gender and Sex Hormones on Nicotine Acute Pharmacological Effects in Mice
J Pharmacol Exp Ther 2001 296: 132-140. [Abstract] [Full Text] [PDF]  

Linda L. Coughenour and Bridget M. Barr

Use of Trifluoroperazine Isolates a [³H]Ifenprodil Binding Site in Rat Brain Membranes with the Pharmacology of the Voltage-Independent Ifenprodil Site on N-Methyl-D-aspartate Receptors Containing NR2B Subunits
J Pharmacol Exp Ther 2001 296: 150-159. [Abstract] [Full Text] [PDF]  

ERRATA:

J Pharmacol Exp Ther 2001 296: 224. [Full Text] [PDF]  

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