ARTICLES:

Ping-Yee Law and Horace H. Loh

Regulation of Opioid Receptor Activities
J Pharmacol Exp Ther 1999 289: 607-624. [Abstract] [Full Text] [PDF]  

R. Ouedraogo, Q.-A. Nguyen, M.-H. Antoine, C. Kane, M.J. Dunne, L. Pochet, B. Masereel, and P. Lebrun

Insulinotropic Effect of New Glibenclamide Isosteres
J Pharmacol Exp Ther 1999 289: 625-631. [Abstract] [Full Text] [PDF]  

Xi-Long Zheng, Yu Gui, Keith A. Sharkey, and Morley D. Hollenberg

Differential Induction of Nitric Oxide Synthase in Rat Gastric and Vascular Smooth Muscle Tissue: Distinct Tissue Distribution and Distinctive Signaling Pathways
J Pharmacol Exp Ther 1999 289: 632-640. [Abstract] [Full Text] [PDF]  

Taylor F. Dowsley, Ken Reid, Dimitri Petsikas, Judith B. Ulreich, Robyn L. Fisher, and Poh-Gek Forkert

Cytochrome P-450-Dependent Bioactivation of 1,1-Dichloroethylene to a Reactive Epoxide in Human Lung and Liver Microsomes
J Pharmacol Exp Ther 1999 289: 641-648. [Abstract] [Full Text] [PDF]  

Marina Tinel, Johny Elkahwaji, Marie Anne Robin, Nicolas Fardel, Veronique Descatoire, Delphine Haouzi, Alain Berson, and Dominique Pessayre

Interleukin-2 Overexpresses c-myc and Down-Regulates Cytochrome P-450 in Rat Hepatocytes
J Pharmacol Exp Ther 1999 289: 649-655. [Abstract] [Full Text] [PDF]  

Raven Reitstetter, Ronald J. Lukas, and Raphael Gruener

Dependence of Nicotinic Acetylcholine Receptor Recovery from Desensitization on the Duration of Agonist Exposure
J Pharmacol Exp Ther 1999 289: 656-660. [Abstract] [Full Text] [PDF]  

Dongtao N. Li, Michael P. Pritchard, Steven P. Hanlon, Brian Burchell, C. Roland Wolf, and Thomas Friedberg

Competition Between Cytochrome P-450 Isozymes for NADPH-Cytochrome P-450 Oxidoreductase Affects Drug Metabolism
J Pharmacol Exp Ther 1999 289: 661-667. [Abstract] [Full Text] [PDF]  

Thomas J. Abbruscato and Thomas P. Davis

Combination of Hypoxia/Aglycemia Compromises In Vitro Blood-Brain Barrier Integrity
J Pharmacol Exp Ther 1999 289: 668-675. [Abstract] [Full Text] [PDF]  

Ryuta Yamazaki, Shinichi Kawai, Tsuneo Matsumoto, Takeshi Matsuzaki, Shusuke Hashimoto, Teruo Yokokura, Renzo Okamoto, Tomihisa Koshino, and Yutaka Mizushima

Hydrolytic Activity Is Essential for Aceclofenac To Inhibit Cyclooxygenase in Rheumatoid Synovial Cells
J Pharmacol Exp Ther 1999 289: 676-681. [Abstract] [Full Text] [PDF]  

Radhika Kajekar, David Proud, Allen C. Myers, Sonya N. Meeker, and Bradley J. Undem

Characterization of Vagal Afferent Subtypes Stimulated by Bradykinin in Guinea Pig Trachea
J Pharmacol Exp Ther 1999 289: 682-687. [Abstract] [Full Text] [PDF]  

Sue A. Aicher and Carrie T. Drake

Clonidine Evokes Vasodepressor Responses via ₂-Adrenergic Receptors in Gigantocellular Reticular Formation
J Pharmacol Exp Ther 1999 289: 688-694. [Abstract] [Full Text] [PDF]  

Troy C. Sarich, Stephen P. Adams, Giorgio Petricca, and James M. Wright

Inhibition of Isoniazid-Induced Hepatotoxicity in Rabbits by Pretreatment with an Amidase Inhibitor
J Pharmacol Exp Ther 1999 289: 695-702. [Abstract] [Full Text] [PDF]  

Jeffrey M. Witkin, Maciej Gasior, Boris Heifets, and Frank C. Tortella

Anticonvulsant Efficacy of N-Methyl-D-Aspartate Antagonists Against Convulsions Induced by Cocaine
J Pharmacol Exp Ther 1999 289: 703-711. [Abstract] [Full Text] [PDF]  

C. S. Celly, W. N. McDonell, and W. D. Black

Cardiopulmonary Effects of the ₂-Adrenoceptor Agonists Medetomidine and ST-91 in Anesthetized Sheep
J Pharmacol Exp Ther 1999 289: 712-720. [Abstract] [Full Text] [PDF]  

Leslie K. Lockhart and Archibald McNicol

The Phospholipase C Inhibitor U73122 Inhibits Phorbol Ester-Induced Platelet Activation
J Pharmacol Exp Ther 1999 289: 721-728. [Abstract] [Full Text] [PDF]  

H. Matsuda, Y. Li, J. Yamahara, and M. Yoshikawa

Inhibition of Gastric Emptying by Triterpene Saponin, Momordin Ic, in Mice: Roles of Blood Glucose, Capsaicin-Sensitive Sensory Nerves, and Central Nervous System
J Pharmacol Exp Ther 1999 289: 729-734. [Abstract] [Full Text] [PDF]  

Francesca Catella-Lawson, Brendan McAdam, Briggs W. Morrison, Shiv Kapoor, Dean Kujubu, Lisa Antes, Kenneth C. Lasseter, Hui Quan, Barry J. Gertz, and Garret A. Fitzgerald

Effects of Specific Inhibition of Cyclooxygenase-2 on Sodium Balance, Hemodynamics, and Vasoactive Eicosanoids
J Pharmacol Exp Ther 1999 289: 735-741. [Abstract] [Full Text] [PDF]  

Eric Bignon, André Bachy, Robert Boigegrain, Roger Brodin, Michèle Cottineau, Danielle Gully, Jean-Marc Herbert, Peter Keane, Christophe Labie, Jean-Charles Molimard, Dominique Olliero, Florence Oury-Donat, Christophe Petereau, Valérie Prabonnaud, Marie-Pierre Rockstroh, Paul Schaeffer, Orlane Servant, Olivier Thurneyssen, Philippe Soubrié, Marc Pascal, Jean-Pierre Maffrand, and Gérard Le Fur

SR146131: A New Potent, Orally Active, and Selective Nonpeptide Cholecystokinin Subtype 1 Receptor Agonist. I: In Vitro Studies
J Pharmacol Exp Ther 1999 289: 742-751. [Abstract] [Full Text] [PDF]  

Eric Bignon, Richard Alonso, Michèle Arnone, Robert Boigegrain, Roger Brodin, Christiane Gueudet, Michel Héaulme, Peter Keane, Marco Landi, Jean-Charles Molimard, Dominique Olliero, Martine Poncelet, Eric Seban, Jacques Simiand, Philippe Soubrié, Marc Pascal, Jean-Pierre Maffrand, and Gérard Le Fur

SR146131: A New Potent, Orally Active, and Selective Nonpeptide Cholecystokinin Subtype 1 Receptor Agonist. II: In Vivo Pharmacological Characterization
J Pharmacol Exp Ther 1999 289: 752-761. [Abstract] [Full Text] [PDF]  

Ron J. Johnson, Gregory D. Fink, and James J. Galligan

Mechanisms of Endothelin-Induced Venoconstriction in Isolated Guinea Pig Mesentery
J Pharmacol Exp Ther 1999 289: 762-767. [Abstract] [Full Text] [PDF]  

Hikaru Yabuuchi, Ikumi Tamai, Jun-Ichi Nezu, Kazuki Sakamoto, Asuka Oku, Miyuki Shimane, Yoshimichi Sai, and Akira Tsuji

Novel Membrane Transporter OCTN1 Mediates Multispecific, Bidirectional, and pH-Dependent Transport of Organic Cations
J Pharmacol Exp Ther 1999 289: 768-773. [Abstract] [Full Text] [PDF]  

Rita A. Cardoso, Susan J. Brozowski, Laura E. Chavez-Noriega, Michael Harpold, C. Fernando Valenzuela, and R. Adron Harris

Effects of Ethanol on Recombinant Human Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes
J Pharmacol Exp Ther 1999 289: 774-780. [Abstract] [Full Text] [PDF]  

Q. Ping Dou, Terence F. McGuire, Yibing Peng, and Bing An

Proteasome Inhibition Leads to Significant Reduction of Bcr-Abl Expression and Subsequent Induction of Apoptosis in K562 Human Chronic Myelogenous Leukemia Cells
J Pharmacol Exp Ther 1999 289: 781-790. [Abstract] [Full Text] [PDF]  

Jack H. Mendelson, Nancy K. Mello, and S. Stevens Negus

Effects of Luteinizing Hormone-Releasing Hormone on Plasma Cocaine Levels in Rhesus Monkeys
J Pharmacol Exp Ther 1999 289: 791-799. [Abstract] [Full Text] [PDF]  

Natalie Serkova, Lawrence Litt, Thomas L. James, Wolfgang Sadée, Dieter Leibfritz, Leslie Z. Benet, and Uwe Christians

Evaluation of Individual and Combined Neurotoxicity of the Immunosuppressants Cyclosporine and Sirolimus by In Vitro Multinuclear NMR Spectroscopy
J Pharmacol Exp Ther 1999 289: 800-806. [Abstract] [Full Text] [PDF]  

Dorothy L. Reimer, Spencer Kong, Myrna Monck, Jessica Wyles, Pat Tam, Ellen K. Wasan, and Marcel B. Bally

Liposomal Lipid and Plasmid DNA Delivery to B16/BL6 Tumors after Intraperitoneal Administration of Cationic Liposome DNA Aggregates
J Pharmacol Exp Ther 1999 289: 807-815. [Abstract] [Full Text] [PDF]  

Shushi Higashi, Naoto Tabata, Kazu-Hiro Kondo, Yorio Maeda, Masataka Shimizu, Tadao Nakashima, and Toshiaki Setoguchi

Size of Lipid Microdroplets Effects Results of Hepatic Arterial Chemotherapy with an Anticancer Agent in Water-in-Oil-in-Water Emulsion to Hepatocellular Carcinoma
J Pharmacol Exp Ther 1999 289: 816-819. [Abstract] [Full Text] [PDF]  

Theresa M. Visarius, Jörg W. Stucki, and Bernhard H. Lauterburg

Inhibition and Stimulation of Long-Chain Fatty Acid Oxidation by Chloroacetaldehyde and Methylene Blue in Rats
J Pharmacol Exp Ther 1999 289: 820-824. [Abstract] [Full Text] [PDF]  

Laura M. King, William A. Banks, and William J. George

Differences in Cadmium Transport to the Testis, Epididymis, and Brain in Cadmium-Sensitive and -Resistant Murine Strains 129/J and A/J
J Pharmacol Exp Ther 1999 289: 825-830. [Abstract] [Full Text] [PDF]  

Ryuichi Sato, Jun Yamazaki, and Taku Nagao

Temporal Differences in Actions of Calcium Channel Blockers on K⁺ Accumulation, Cardiac Function, and High-Energy Phosphate Levels in Ischemic Guinea Pig Hearts
J Pharmacol Exp Ther 1999 289: 831-839. [Abstract] [Full Text] [PDF]  

Kathleen A. Sluka, Merek Deacon, Andrea Stibal, Shannon Strissel, and Amy Terpstra

Spinal Blockade of Opioid Receptors Prevents the Analgesia Produced by TENS in Arthritic Rats
J Pharmacol Exp Ther 1999 289: 840-846. [Abstract] [Full Text] [PDF]  

Anastasia Simi and Magnus Ingelman-Sundberg

Post-Translational Inhibition of Cytochrome P-450 2E1 Expression by Chlomethiazole in Fao Hepatoma Cells
J Pharmacol Exp Ther 1999 289: 847-852. [Abstract] [Full Text] [PDF]  

Xiaoxiong Wei, Renke Dai, Suoping Zhai, Kenneth E. Thummel, Fred K. Friedman, and Robert E. Vestal

Inhibition of Human Liver Cytochrome P-450 1A2 by the Class IB Antiarrhythmics Mexiletine, Lidocaine, and Tocainide
J Pharmacol Exp Ther 1999 289: 853-858. [Abstract] [Full Text] [PDF]  

Diana L. Cichewicz, Zachary L. Martin, Forrest L. Smith, and Sandra P. Welch

Enhancement of µ Opioid Antinociception by Oral ⁹-Tetrahydrocannabinol: Dose-Response Analysis and Receptor Identification
J Pharmacol Exp Ther 1999 289: 859-867. [Abstract] [Full Text] [PDF]  

M. Cui, Y. Feng, D. J. McAdoo, and W. D. Willis

Periaqueductal Gray Stimulation-Induced Inhibition of Nociceptive Dorsal Horn Neurons in Rats Is Associated with the Release of Norepinephrine, Serotonin, and Amino Acids
J Pharmacol Exp Ther 1999 289: 868-876. [Abstract] [Full Text] [PDF]  

Amy J. Eshleman, Marya Carmolli, Medhane Cumbay, Carey R. Martens, Kim A. Neve, and Aaron Janowsky

Characteristics of Drug Interactions with Recombinant Biogenic Amine Transporters Expressed in the Same Cell Type
J Pharmacol Exp Ther 1999 289: 877-885. [Abstract] [Full Text] [PDF]  

Nancy W. Kleckner, Jill C. Glazewski, Chi Chiung Chen, and Tammy D. Moscrip

Subtype-Selective Antagonism of N-Methyl-D-Aspartate Receptors by Felbamate: Insights into the Mechanism of Action
J Pharmacol Exp Ther 1999 289: 886-894. [Abstract] [Full Text] [PDF]  

Aman S. Hussain, Natascha H. Crispino, Brian E. McLaughlin, James F. Brien, Gerald S. Marks, and Kanji Nakatsu

Glyceryl Trinitrate-Induced Vasodilation Is Inhibited by Ultraviolet Irradiation Despite Enhanced Nitric Oxide Generation: Evidence for Formation of a Nitric Oxide Conjugate
J Pharmacol Exp Ther 1999 289: 895-900. [Abstract] [Full Text] [PDF]  

Jeffrey S. Fedan, Long-Xing Yuan, Victoria C. Chang, Joseph O. Viola, Deborah Cutler, and Loreen L. Pettit

Osmotic Regulation of Airway Reactivity by Epithelium
J Pharmacol Exp Ther 1999 289: 901-910. [Abstract] [Full Text] [PDF]  

Juanita Dortch-Carnes, Michael R. van Scott, and Jeffrey S. Fedan

Changes in Smooth Muscle Tone During Osmotic Challenge in Relation to Epithelial Bioelectric Events in Guinea Pig Isolated Trachea
J Pharmacol Exp Ther 1999 289: 911-917. [Abstract] [Full Text] [PDF]  

Rafael F. Schäfers, Jens Nürnberger, Burghard Herrmann, Rene R. Wenzel, Thomas Philipp, and Martin C. Michel

Adrenoceptors Mediating the Cardiovascular and Metabolic Effects of -Methylnoradrenaline in Humans
J Pharmacol Exp Ther 1999 289: 918-925. [Abstract] [Full Text] [PDF]  

Shigeru Okuyama, Shigeyuki Chaki, Naoya Kawashima, Yoshiko Suzuki, Shin-Ichi Ogawa, Atsuro Nakazato, Toshihito Kumagai, Taketoshi Okubo, and Kazuyuki Tomisawa

Receptor Binding, Behavioral, and Electrophysiological Profiles of Nonpeptide Corticotropin-Releasing Factor Subtype 1 Receptor Antagonists CRA1000 and CRA1001
J Pharmacol Exp Ther 1999 289: 926-935. [Abstract] [Full Text] [PDF]  

Thomas Eissenberg, Maxine L. Stitzer, George E. Bigelow, August R. Buchhalter, and Sharon L. Walsh

Relative Potency of levo--Acetylmethadol and Methadone in Humans under Acute Dosing Conditions
J Pharmacol Exp Ther 1999 289: 936-945. [Abstract] [Full Text] [PDF]  

Neil W. Delapp, Jamie H. McKinzie, Barry D. Sawyer, Amy Vandergriff, Julie Falcone, Don McClure, and Christian C. Felder

Determination of [³⁵S]Guanosine-5'-O-(3-thio)Triphosphate Binding Mediated by Cholinergic Muscarinic Receptors in Membranes from Chinese Hamster Ovary Cells and Rat Striatum Using an Anti-G Protein Scintillation Proximity Assay
J Pharmacol Exp Ther 1999 289: 946-955. [Abstract] [Full Text] [PDF]  

John A. Schetz, Alice Chu, and David R. Sibley

Zinc Modulates Antagonist Interactions with D₂-Like Dopamine Receptors through Distinct Molecular Mechanisms
J Pharmacol Exp Ther 1999 289: 956-964. [Abstract] [Full Text] [PDF]  

Drake Morgan, Charles D. Cook, and Mitchell J. Picker

Sensitivity to the Discriminative Stimulus and Antinociceptive Effects of µ Opioids: Role of Strain of Rat, Stimulus Intensity, and Intrinsic Efficacy at the µ Opioid Receptor
J Pharmacol Exp Ther 1999 289: 965-975. [Abstract] [Full Text] [PDF]  

Ramona Almirez and Andrew A. Protter

Clearance of Human Brain Natriuretic Peptide in Rabbits; Effect of the Kidney, the Natriuretic Peptide Clearance Receptor, and Peptidase Activity
J Pharmacol Exp Ther 1999 289: 976-980. [Abstract] [Full Text] [PDF]  

Frederick J. Ehlert, Michael T. Griffin, Gregory W. Sawyer, and Regina Bailon

A Simple Method for Estimation of Agonist Activity at Receptor Subtypes: Comparison of Native and Cloned M₃ Muscarinic Receptors in Guinea Pig Ileum and Transfected Cells
J Pharmacol Exp Ther 1999 289: 981-992. [Abstract] [Full Text] [PDF]  

Robert W. Hurley, Theodore S. Grabow, Ronald J. Tallarida, and Donna L. Hammond

Interaction Between Medullary and Spinal ₁ and ₂ Opioid Receptors in the Production of Antinociception in the Rat
J Pharmacol Exp Ther 1999 289: 993-999. [Abstract] [Full Text] [PDF]  

V. L. Arvanov and R. Y. Wang

Clozapine, But Not Haloperidol, Prevents the Functional Hyperactivity of N-Methyl-D-Aspartate Receptors in Rat Cortical Neurons Induced by Subchronic Administration of Phencyclidine
J Pharmacol Exp Ther 1999 289: 1000-1006. [Abstract] [Full Text] [PDF]  

Clifford D. Wright, Andrew M. Havill, Scot C. Middleton, Mohammed A. Kashem, Patrice A. Lee, David J. Dripps, Thomas G. O'Riordan, Michael P. Bevilacqua, and William M. Abraham

Secretory Leukocyte Protease Inhibitor Prevents Allergen-Induced Pulmonary Responses in Animal Models of Asthma
J Pharmacol Exp Ther 1999 289: 1007-1014. [Abstract] [Full Text] [PDF]  

Rozenn Clement, Jean-Marc Malinovsky, Pascal Le Corre, Gilles Dollo, Francois Chevanne, and Roger Le Verge

Cerebrospinal Fluid Bioavailability and Pharmacokinetics of Bupivacaine and Lidocaine after Intrathecal and Epidural Administrations in Rabbits Using Microdialysis
J Pharmacol Exp Ther 1999 289: 1015-1021. [Abstract] [Full Text] [PDF]  

Bruno Palmier, Monique Vacher, Simone Harbon, and Denis Leiber

A Tyrosine Kinase Signaling Pathway, Regulated by Calcium Entry and Dissociated from Tyrosine Phosphorylation of Phospholipase C-1, Is Involved in Inositol Phosphate Production by Activated G Protein-Coupled Receptors in Myometrium
J Pharmacol Exp Ther 1999 289: 1022-1030. [Abstract] [Full Text] [PDF]  

Smriti Iyengar, Dominic L. Li, and Rosa Maria A. Simmons

Characterization of Neuropeptide Y-Induced Feeding in Mice: Do Y1-Y6 Receptor Subtypes Mediate Feeding?
J Pharmacol Exp Ther 1999 289: 1031-1040. [Abstract] [Full Text] [PDF]  

Terre A. Sharma and Ian J. Reynolds

Characterization of the Effects of Polyamines on [¹²⁵I]MK-801 Binding to Recombinant N-Methyl-D-Aspartate Receptors
J Pharmacol Exp Ther 1999 289: 1041-1047. [Abstract] [Full Text] [PDF]  

Antonia M. Davis and Charles E. Inturrisi

d-Methadone Blocks Morphine Tolerance and N-Methyl-D-Aspartate-Induced Hyperalgesia
J Pharmacol Exp Ther 1999 289: 1048-1053. [Abstract] [Full Text] [PDF]  

Burhan I. Ghanayem, J. Michael Sanders, Brian Chanas, Leo T. Burka, and Frank J. Gonzalez

Role of Cytochrome P-450 2E1 in Methacrylonitrile Metabolism and Disposition
J Pharmacol Exp Ther 1999 289: 1054-1059. [Abstract] [Full Text] [PDF]  

Toril Rabben, Per Skjelbred, and Ivar Øye

Prolonged Analgesic Effect of Ketamine, an N-Methyl-D-Aspartate Receptor Inhibitor, in Patients with Chronic Pain
J Pharmacol Exp Ther 1999 289: 1060-1066. [Abstract] [Full Text] [PDF]  

B. Tuk, M. F. van Oostenbruggen, V. M. M. Herben, J. W. Mandema, and M. Danhof

Characterization of the Pharmacodynamic Interaction between Parent Drug and Active Metabolite In Vivo: Midazolam and -OH-Midazolam
J Pharmacol Exp Ther 1999 289: 1067-1074. [Abstract] [Full Text] [PDF]  

Jian-Hua Zhang, Jodie M. Hanesworth, Michael F. Sardinia, Jeremiah A. Alt, John W. Wright, and Joseph W. Harding

Structural Analysis of Angiotensin IV Receptor (AT₄) from Selected Bovine Tissues
J Pharmacol Exp Ther 1999 289: 1075-1083. [Abstract] [Full Text] [PDF]  

Thomas K. Henthorn, Yang Liu, Mrinal Mahapatro, and Ka-yun Ng

Active Transport of Fentanyl by the Blood-Brain Barrier
J Pharmacol Exp Ther 1999 289: 1084-1089. [Abstract] [Full Text] [PDF]  

Michael J. Marks, Paul Whiteaker, Jennifer Calcaterra, Jerry A. Stitzel, Amy E. Bullock, Sharon R. Grady, Marina R. Picciotto, Jean-Pierre Changeux, and Allan C. Collins

Two Pharmacologically Distinct Components of Nicotinic Receptor-Mediated Rubidium Efflux in Mouse Brain Require the 2 Subunit
J Pharmacol Exp Ther 1999 289: 1090-1103. [Abstract] [Full Text] [PDF]  

Rosalinde Masereeuw, Miek M. Moons, Barbara H. Toomey, Frans G. M. Russel, and David S. Miller

Active Lucifer Yellow Secretion in Renal Proximal Tubule: Evidence for Organic Anion Transport System Crossover
J Pharmacol Exp Ther 1999 289: 1104-1111. [Abstract] [Full Text] [PDF]  

Jeehyeon Bae, Marc Peters-Golden, and Rita Loch-Caruso

Stimulation of Pregnant Rat Uterine Contraction by the Polychlorinated Biphenyl (PCB) Mixture Aroclor 1242 May Be Mediated by Arachidonic Acid Release through Activation of Phospholipase A₂ Enzymes
J Pharmacol Exp Ther 1999 289: 1112-1120. [Abstract] [Full Text] [PDF]  

Kimberley J. Woodcroft and Raymond F. Novak

Insulin Differentially Affects Xenobiotic-Enhanced, Cytochrome P-450 (CYP)2E1, CYP2B, CYP3A, and CYP4A Expression in Primary Cultured Rat Hepatocytes
J Pharmacol Exp Ther 1999 289: 1121-1127. [Abstract] [Full Text] [PDF]  

Peter K. Working, Mary S. Newman, Timothy Sullivan, and John Yarrington

Reduction of the Cardiotoxicity of Doxorubicin in Rabbits and Dogs by Encapsulation in Long-Circulating, Pegylated Liposomes
J Pharmacol Exp Ther 1999 289: 1128-1133. [Abstract] [Full Text] [PDF]  

Jeannine M. Fisher, Steven A. Wrighton, Paul B. Watkins, Phyllissa Schmiedlin-Ren, Justina C. Calamia, Danny D. Shen, Kent L. Kunze, and Kenneth E. Thummel

First-Pass Midazolam Metabolism Catalyzed by 1,25-Dihydroxy Vitamin D₃-Modified Caco-2 Cell Monolayers
J Pharmacol Exp Ther 1999 289: 1134-1142. [Abstract] [Full Text] [PDF]  

Jeannine M. Fisher, Steven A. Wrighton, Justina C. Calamia, Danny D. Shen, Kent L. Kunze, and Kenneth E. Thummel

Midazolam Metabolism by Modified Caco-2 Monolayers: Effects of Extracellular Protein Binding
J Pharmacol Exp Ther 1999 289: 1143-1150. [Abstract] [Full Text] [PDF]  

Stephen L. Yates, James G. Phillips, Rosilyn Gregory, Gary P. Pawlowski, Leena Fadnis, M. Amin Khan, Syed M. Ali, and Clark E. Tedford

Identification and Pharmacological Characterization of a Series of New 1H-4-Substituted-Imidazoyl Histamine H₃ Receptor Ligands
J Pharmacol Exp Ther 1999 289: 1151-1159. [Abstract] [Full Text] [PDF]  

Clark E. Tedford, James G. Phillips, Rosilyn Gregory, Gary P. Pawlowski, Leena Fadnis, M. Amin Khan, Syed M. Ali, Michael K. Handley, and Stephen L. Yates

Development of trans-2-[1H-Imidazol-4-yl] Cyclopropane Derivatives as New High-Affinity Histamine H₃ Receptor Ligands
J Pharmacol Exp Ther 1999 289: 1160-1168. [Abstract] [Full Text] [PDF]  

Valerie Furlan, Sylvie Demirdjian, Olivier Bourdon, Jacques Magdalou, and Anne-Marie Taburet

Glucuronidation of Drugs by Hepatic Microsomes Derived from Healthy and Cirrhotic Human Livers
J Pharmacol Exp Ther 1999 289: 1169-1175. [Abstract] [Full Text] [PDF]  

Yoshiyuki Yabe, Makiya Nishikawa, Ayumi Tamada, Yoshinobu Takakura, and Mitsuru Hashida

Targeted Delivery and Improved Therapeutic Potential of Catalase by Chemical Modification: Combination with Superoxide Dismutase Derivatives
J Pharmacol Exp Ther 1999 289: 1176-1184. [Abstract] [Full Text] [PDF]  

ERRATA:

Correction for vol. 288, p. 1143
J Pharmacol Exp Ther 1999 289: 1184. [Full Text]  

Correction for vol. 289, p. 8
J Pharmacol Exp Ther 1999 289: 1184. [Full Text]  

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