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Other Issues:
February 1999; 288 (2)   [Index by Author]  [Cover Caption]
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ARTICLES:

Carola Severi, Veronica Carnicelli, Antonio di Giulio, Giovanna Romano, Argante Bozzi, Arduino Oratore, Roberto Strom, and Gianfranco Delle Fave
Progression from Homologous to Heterologous Desensitization of Contraction in Gastric Smooth Muscle Cells
J Pharmacol Exp Ther 1999 288: 389-398. [Abstract] [Full Text] [PDF]  

Saleh Abu-Raya, Eugenia Bloch-Shilderman, Peter I. Lelkes, Victoria Trembovler, Esther Shohami, Yehuda Gutman, and Philip Lazarovici
Characterization of Pardaxin-Induced Dopamine Release from Pheochromocytoma Cells: Role of Calcium and Eicosanoids
J Pharmacol Exp Ther 1999 288: 399-406. [Abstract] [Full Text] [PDF]  

Venu Jain, Yurij P. Vedernikov, George R. Saade, Kristof Chwalisz, and Robert E. Garfield
Endothelium-Dependent and -Independent Mechanisms of Vasorelaxation by Corticotropin-Releasing Factor in Pregnant Rat Uterine Artery
J Pharmacol Exp Ther 1999 288: 407-413. [Abstract] [Full Text] [PDF]  

Lucia Sabordo, Benedetta C. Sallustio, Allan M. Evans, and Roger L. Nation
Hepatic Disposition of the Acyl Glucuronide1-O-Gemfibrozil-beta -D-Glucuronide: Effects of Dibromosulfophthalein on Membrane Transport and Aglycone Formation
J Pharmacol Exp Ther 1999 288: 414-420. [Abstract] [Full Text] [PDF]  

Michael S. Saporito, Ellen M. Brown, Matthew S. Miller, and Susan Carswell
CEP-1347/KT-7515, an Inhibitor of c-jun N-Terminal Kinase Activation, Attenuates the 1-Methyl-4-Phenyl Tetrahydropyridine-Mediated Loss of Nigrostriatal Dopaminergic Neurons In Vivo
J Pharmacol Exp Ther 1999 288: 421-427. [Abstract] [Full Text] [PDF]  

Raymond B. Penn, Jean-Luc Parent, Alexey N. Pronin, Reynold A. Panettieri, Jr., and Jeffrey L. Benovic
Pharmacological Inhibition of Protein Kinases in Intact Cells: Antagonism of Beta Adrenergic Receptor Ligand Binding by H-89 Reveals Limitations of Usefulness
J Pharmacol Exp Ther 1999 288: 428-437. [Abstract] [Full Text] [PDF]  

Jodie J. Rady, Gregory I. Elmer, and James M. Fujimoto
Opioid Receptor Selectivity of Heroin Given Intracerebroventricularly Differs in Six Strains of Inbred Mice
J Pharmacol Exp Ther 1999 288: 438-445. [Abstract] [Full Text] [PDF]  

Beth Musser, Ramagopal V. Mudumbi, Jingwen Liu, Richard D. Olson, and Robert E. Vestal
Adenosine A1 Receptor-Dependent and -Independent Effects of the Allosteric Enhancer PD 81,723
J Pharmacol Exp Ther 1999 288: 446-454. [Abstract] [Full Text] [PDF]  

Mahmoud M. El-Mas and Abdel A. Abdel-Rahman
Ethanol Counteraction of I1-Imidazoline but Not Alpha-2 Adrenergic Receptor-Mediated Reduction in Vascular Resistance in Conscious Spontaneously Hypertensive Rats
J Pharmacol Exp Ther 1999 288: 455-462. [Abstract] [Full Text] [PDF]  

Xiaoliang Zhuo, Jun Gu, Qing-Yu Zhang, David C. Spink, Laurence S. Kaminsky, and Xinxin Ding
Biotransformation of Coumarin by Rodent and Human Cytochromes P-450: Metabolic Basis of Tissue-Selective Toxicity in Olfactory Mucosa of Rats and Mice
J Pharmacol Exp Ther 1999 288: 463-471. [Abstract] [Full Text] [PDF]  

Gerwin Roks, Charles L.P. Deckers, Harry Meinardi, Ris Dirksen, Jan van Egmond, and Clementina M. van Rijn
Effects of Polytherapy Compared With Monotherapy in Antiepileptic Drugs: An Animal Study
J Pharmacol Exp Ther 1999 288: 472-477. [Abstract] [Full Text] [PDF]  

Andrew N. Gifford, Magalie Bruneus, S. John Gatley, Ruoxi Lan, Alexandros Makriyannis, and Nora D. Volkow
Large Receptor Reserve for Cannabinoid Actions in the Central Nervous System
J Pharmacol Exp Ther 1999 288: 478-483. [Abstract] [Full Text] [PDF]  

Bertrand J. Jean-Claude, Amir Mustafa, Amanda J. Watson, Zoe Damian, Daniela Vasilescu, Tak Hang Chan, and Brian Leyland-Jones
Tetrazepinones Are Equally Cytotoxic to Mer+ and Mer- Human Tumor Cell Lines
J Pharmacol Exp Ther 1999 288: 484-489. [Abstract] [Full Text] [PDF]  

A. High, T. Prior, R. A. Bell, and P. K. Rangachari
Probing the "Active Site" of Diamine Oxidase: Structure-Activity Relations for Histamine Potentiation by O-Alkylhydroxylamines on Colonic Epithelium
J Pharmacol Exp Ther 1999 288: 490-501. [Abstract] [Full Text] [PDF]  

Donald T. Lysle and Tam How
Endogenous Opioids Regulate the Expression of Inducible Nitric Oxide Synthase by Splenocytes
J Pharmacol Exp Ther 1999 288: 502-508. [Abstract] [Full Text] [PDF]  

V. Srikanth, T. Malini, J. Arunakaran, P. Govindarajulu, and K. Balasubramanian
Effects of Ethanol Treatment on Epididymal Secretory Products and Sperm Maturation in Albino Rats
J Pharmacol Exp Ther 1999 288: 509-515. [Abstract] [Full Text] [PDF]  

Daniel J. Martin, Joseph A. Toce, Phillip J. Anevski, Douglas M. Tollefsen, and Dana R. Abendschein
Anticoagulant and Antithrombotic Activity of Maltodapoh, a Novel Sulfated Tetrasaccharide
J Pharmacol Exp Ther 1999 288: 516-521. [Abstract] [Full Text] [PDF]  

Kiyoshi Tadano, Tomoyuki Yamasaki, and Yasuo Matsumura
Inhibitory Effects of Proadrenomedullin N-terminal 20 Peptide on Antidiuresis and Norepinephrine Overflow Induced by Stimulation of Renal Nerves in Anesthetized Dogs
J Pharmacol Exp Ther 1999 288: 522-528. [Abstract] [Full Text] [PDF]  

Jian Luo, Jeanne Cheung, Eileen M. Yevich, John P. Clark, Joyce Tsai, Priscilla Lapresca, Rosa P. Ubillas, Diana M. Fort, Thomas J, Carlson, Richard F. Hector, Steven R. King, Christopher D. Mendez, S. D. Jolad, and Gerald M. Reaven
Novel Terpenoid-Type Quinones Isolated from Pycnanthus angolensis of Potential Utility in the Treatment of Type 2 Diabetes
J Pharmacol Exp Ther 1999 288: 529-534. [Abstract] [Full Text] [PDF]  

Chyan E. Lau, Fang Ma, David M. Foster, and John L. Falk
Pharmacokinetic-Pharmacodynamic Modeling of the Psychomotor Stimulant Effect of Cocaine after Intravenous Administration: Timing Performance Deficits
J Pharmacol Exp Ther 1999 288: 535-543. [Abstract] [Full Text] [PDF]  

Xian-Cheng Yang and Donald J. Reis
Agmatine Selectively Blocks the N-Methyl-D-Aspartate Subclass of Glutamate Receptor Channels in Rat Hippocampal Neurons
J Pharmacol Exp Ther 1999 288: 544-549. [Abstract] [Full Text] [PDF]  

Francis H. E. Wojnicki, Richard B. Rothman, Kenner C. Rice, and John R. Glowa
Effects of Phentermine on Responding Maintained under Multiple Fixed-Ratio Schedules of Food and Cocaine Presentation in the Rhesus Monkey
J Pharmacol Exp Ther 1999 288: 550-560. [Abstract] [Full Text] [PDF]  

D. K. Raap, F. Garcia, N. A. Muma, W. A. Wolf, G. Battaglia, and L. D. van de Kar
Sustained Desensitization of Hypothalamic 5-Hydroxytryptamine1A Receptors after Discontinuation of Fluoxetine: Inhibited Neuroendocrine Responses to 8-Hydroxy-2-(Dipropylamino)Tetralin in the Absence of Changes in Gi/o/z Proteins
J Pharmacol Exp Ther 1999 288: 561-567. [Abstract] [Full Text] [PDF]  

Yukio Kato, Sharif Akhteruzzaman, Akihiro Hisaka, and Yuichi Sugiyama
Hepatobiliary Transport Governs Overall Elimination of Peptidic Endothelin Antagonists in Rats
J Pharmacol Exp Ther 1999 288: 568-574. [Abstract] [Full Text] [PDF]  

Sharif Akhteruzzaman, Yukio Kato, Akihiro Hisaka, and Yuichi Sugiyama
Primary Active Transport of Peptidic Endothelin Antagonists by Rat Hepatic Canalicular Membrane
J Pharmacol Exp Ther 1999 288: 575-581. [Abstract] [Full Text] [PDF]  

Marielle Portier, Murielle Rinaldi-Carmona, Florence Pecceu, Thérèse Combes, Caroline Poinot-Chazel, Bernard Calandra, Francis Barth, Gérard Le Fur, and Pierre Casellas
SR 144528, an Antagonist for the Peripheral Cannabinoid Receptor that Behaves as an Inverse Agonist
J Pharmacol Exp Ther 1999 288: 582-589. [Abstract] [Full Text] [PDF]  

S. Morisset, U. G. Sahm, E. Traiffort, J. Tardivel-Lacombe, J. M. Arrang, and J.-C. Schwartz
Atypical Neuroleptics Enhance Histamine Turnover in Brain Via 5-Hydroxytryptamine2A Receptor Blockade
J Pharmacol Exp Ther 1999 288: 590-596. [Abstract] [Full Text] [PDF]  

Wanping Geng and K. Sandy Pang
Differences in Excretion of Hippurate, as a Metabolite of Benzoate and as an Administered Species, in the Single-Pass Isolated Perfused Rat Kidney Explained
J Pharmacol Exp Ther 1999 288: 597-606. [Abstract] [Full Text] [PDF]  

Jules A. Desmeules, Mitsuko Kondo Oestreicher, Valérie Piguet, Anne-Françoise Allaz, and Pierre Dayer
Contribution of Cytochrome P-4502D6 Phenotype to the Neuromodulatory Effects of Dextromethorphan
J Pharmacol Exp Ther 1999 288: 607-612. [Abstract] [Full Text] [PDF]  

R. F. Hoernlein, Th. Orlikowsky, C. Zehrer, D. Niethammer, E. R. Sailer, Th. Simmet, G. E. Dannecker, and H. P. T. Ammon
Acetyl-11-Keto-beta -Boswellic Acid Induces Apoptosis in HL-60 and CCRF-CEM Cells and Inhibits Topoisomerase I
J Pharmacol Exp Ther 1999 288: 613-619. [Abstract] [Full Text] [PDF]  

Osamu Furukawa, Hiroshi Matsui, Noriko Suzuki, and Susumu Okabe
Epidermal Growth Factor Protects Rat Epithelial Cells Against Acid-Induced Damage Through the Activation of Na+/H+ Exchangers
J Pharmacol Exp Ther 1999 288: 620-626. [Abstract] [Full Text] [PDF]  

Hirokazu Kouzuki, Hiroshi Suzuki, Kousei Ito, Rui Ohashi, and Yuichi Sugiyama
Contribution of Organic Anion Transporting Polypeptide to Uptake of Its Possible Substrates into Rat Hepatocytes
J Pharmacol Exp Ther 1999 288: 627-634. [Abstract] [Full Text] [PDF]  

R. Daniel Mellon and Barbara M. Bayer
The Effects of Morphine, Nicotine and Epibatidine on Lymphocyte Activity and Hypothalamic-Pituitary-Adrenal Axis Responses
J Pharmacol Exp Ther 1999 288: 635-642. [Abstract] [Full Text] [PDF]  

Vaishali P. Bakshi, Mark Tricklebank, Hans C. Neijt, Virginia Lehmann-Masten, and Mark A. Geyer
Disruption of Prepulse Inhibition and Increases in Locomotor Activity by Competitive N-Methyl-D-aspartate Receptor Antagonists in Rats
J Pharmacol Exp Ther 1999 288: 643-652. [Abstract] [Full Text] [PDF]  

D. Bochelen, M. Rudin, and A. Sauter
Calcineurin Inhibitors FK506 and SDZ ASM 981 Alleviate the Outcome of Focal Cerebral Ischemic/Reperfusion Injury
J Pharmacol Exp Ther 1999 288: 653-659. [Abstract] [Full Text] [PDF]  

Titti Martinsson
Ropivacaine Inhibits Serum-Induced Proliferation of Colon Adenocarcinoma Cells In Vitro
J Pharmacol Exp Ther 1999 288: 660-664. [Abstract] [Full Text] [PDF]  

W. T. Phillips, R. W. Klipper, V. D. Awasthi, A. S. Rudolph, R. Cliff, V. Kwasiborski, and B. A. Goins
Polyethylene Glycol-Modified Liposome-Encapsulated Hemoglobin: A Long Circulating Red Cell Substitute
J Pharmacol Exp Ther 1999 288: 665-670. [Abstract] [Full Text] [PDF]  

Bruce P. Damiano, Wai-Man Cheung, Rosemary J. Santulli, Wai-Ping Fung-Leung, Karen Ngo, Richard D. Ye, Andrew L. Darrow, Claudia K. Derian, Lawrence de Garavilla, and Patricia Andrade-Gordon
Cardiovascular Responses Mediated by Protease-Activated Receptor-2 (PAR-2) and Thrombin Receptor (PAR-1) are Distinguished in Mice Deficient in PAR-2 or PAR-1
J Pharmacol Exp Ther 1999 288: 671-678. [Abstract] [Full Text] [PDF]  

Tushar G. Kokate, Melissa K. Banks, Tamika Magee, Shun-Ichi Yamaguchi, and Michael A. Rogawski
Finasteride, a 5alpha -Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice
J Pharmacol Exp Ther 1999 288: 679-684. [Abstract] [Full Text] [PDF]  

Bing Shi, James E. Heavner, Jian Liu, Martin J. Wang, Lorenz O. Lutherer, Dan C. McIntyre, and Charles E. Reigel
Two Genetically Selected Strains of Rats Exhibit Hypersensitivity or Resistance to Cocaine-Induced Fatal Arrhythmias
J Pharmacol Exp Ther 1999 288: 685-692. [Abstract] [Full Text] [PDF]  

Chris Baylis, Jeff Harvey, Beth R. Santmyire, and Kevin Engels
Pressor and Renal Vasoconstrictor Responses to Acute Systemic Nitric Oxide Synthesis Inhibition Are Independent of the Sympathetic Nervous System and Angiotensin II
J Pharmacol Exp Ther 1999 288: 693-698. [Abstract] [Full Text] [PDF]  

Ronald Kuczenski and David S. Segal
Sensitization of Amphetamine-Induced Stereotyped Behaviors During the Acute Response
J Pharmacol Exp Ther 1999 288: 699-709. [Abstract] [Full Text] [PDF]  

David Feifel, Tammi L. Reza, David J. Wustrow, and M. Duff Davis
Novel Antipsychotic-Like Effects on Prepulse Inhibition of Startle Produced by a Neurotensin Agonist
J Pharmacol Exp Ther 1999 288: 710-713. [Abstract] [Full Text] [PDF]  

Seddigheh Razani-Boroujerdi, Bruce Edwards, and Mohan L. Sopori
Lead Stimulates Lymphocyte Proliferation Through Enhanced T Cell-B Cell Interaction
J Pharmacol Exp Ther 1999 288: 714-719. [Abstract] [Full Text] [PDF]  

Yu-Nien Sun, Lorraine I. McKay, Debra C. DuBois, William J. Jusko, and Richard R. Almon
Pharmacokinetic/Pharmacodynamic Models for Corticosteroid Receptor Down-Regulation and Glutamine Synthetase Induction in Rat Skeletal Muscle by a Receptor/Gene-Mediated Mechanism
J Pharmacol Exp Ther 1999 288: 720-728. [Abstract] [Full Text] [PDF]  

Marilyn H. Perrin, Steve W. Sutton, Laura A. Cervini, Jean E. Rivier, and Wylie W. Vale
Comparison of an Agonist, Urocortin, and an Antagonist, Astressin, as Radioligands for Characterization of Corticotropin-Releasing Factor Receptors
J Pharmacol Exp Ther 1999 288: 729-734. [Abstract] [Full Text] [PDF]  

Xiao-Yan Chu, Hiroshi Suzuki, Kaoru Ueda, Yukio Kato, Shin-Ichi Akiyama, and Yuichi Sugiyama
Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines
J Pharmacol Exp Ther 1999 288: 735-741. [Abstract] [Full Text] [PDF]  

Xiaoping Zhang, Fabio A. Recchia, Robert Bernstein, Xiaobin Xu, Alberto Nasjletti, and Thomas H. Hintze
Kinin-Mediated Coronary Nitric Oxide Production Contributes to the Therapeutic Action of Angiotensin-Converting Enzyme and Neutral Endopeptidase Inhibitors and Amlodipine in the Treatment in Heart Failure
J Pharmacol Exp Ther 1999 288: 742-751. [Abstract] [Full Text] [PDF]  

William P. Melega, Arthur K. Cho, Debra Schmitz, Ronald Kuczenski, and David S. Segal
l-Methamphetamine Pharmacokinetics and Pharmacodynamics for Assessment of In Vivo Deprenyl-Derived l-Methamphetamine
J Pharmacol Exp Ther 1999 288: 752-758. [Abstract] [Full Text] [PDF]  

Alice A. Larson and Kelley F. Kitto
Chelation of Zinc in the Extracellular Area of the Spinal Cord, Using Ethylenediaminetetraacetic Acid Disodium-Calcium Salt or Dipicolinic Acid, Inhibits the Antinociceptive Effect of Capsaicin in Adult Mice
J Pharmacol Exp Ther 1999 288: 759-765. [Abstract] [Full Text] [PDF]  

Reto Babst, Lucilla Bongiorno, Mario Marini, L. Giorgio Roda, Giulio Spagnoli, and Alessandra Urbani
Trauma Decreases Leucine Enkephalin Hydrolysis in Human Plasma
J Pharmacol Exp Ther 1999 288: 766-773. [Abstract] [Full Text] [PDF]  

Toshihide Kuroki, Herbert Y. Meltzer, and Junji Ichikawa
Effects of Antipsychotic Drugs on Extracellular Dopamine Levels in Rat Medial Prefrontal Cortex and Nucleus Accumbens
J Pharmacol Exp Ther 1999 288: 774-781. [Abstract] [Full Text] [PDF]  

Deborah A. Finn and John C. Crabbe
Chronic Ethanol Differentially Alters Susceptibility to Chemically Induced Convulsions in Withdrawal Seizure-Prone and -Resistant Mice
J Pharmacol Exp Ther 1999 288: 782-790. [Abstract] [Full Text] [PDF]  

Kan He, Thomas F. Woolf, and Paul F. Hollenberg
Mechanism-Based Inactivation of Cytochrome P-450-3A4 by Mifepristone (RU486)
J Pharmacol Exp Ther 1999 288: 791-797. [Abstract] [Full Text] [PDF]  

Philippe Chopin, Francis C. Colpaert, and Marc Marien
Effects of Alpha-2 Adrenoceptor Agonists and Antagonists on Circling Behavior in Rats with Unilateral 6-Hydroxydopamine Lesions of the Nigrostriatal Pathway
J Pharmacol Exp Ther 1999 288: 798-804. [Abstract] [Full Text] [PDF]  

U. Vahlensieck, P. Bokník, I. Gombosová, S. Huke, J. Knapp, B. Linck, H. Lüb, F. U. Müller, J. Neumann, M. C. Deng, H. H. Scheld, H. Jankowski, H. Schlüter, W. Zidek, N. Zimmermann, and W. Schmitz
Inotropic Effects of Diadenosine Tetraphosphate (AP4A) in Human and Animal Cardiac Preparations
J Pharmacol Exp Ther 1999 288: 805-813. [Abstract] [Full Text] [PDF]  

Jia Wei Ye, Jing Xia Cai, Li Ming Wang, and Xi Can Tang
Improving Effects of Huperzine A on Spatial Working Memory in Aged Monkeys and Young Adult Monkeys with Experimental Cognitive Impairment
J Pharmacol Exp Ther 1999 288: 814-819. [Abstract] [Full Text] [PDF]  

Lynn P. Martin, David M. Jackson, Carin Wallsten, and Barbara L. Waszczak
Electrophysiological Comparison of 5-Hydroxytryptamine1A Receptor Antagonists on Dorsal Raphe Cell Firing
J Pharmacol Exp Ther 1999 288: 820-826. [Abstract] [Full Text] [PDF]  

Ann E. Remmers, Mary J. Clark, Alfred Mansour, Huda Akil, James H. Woods, and Fedor Medzihradsky
Opioid Efficacy in a C6 Glioma Cell Line Stably Expressing the Human Kappa Opioid Receptor
J Pharmacol Exp Ther 1999 288: 827-833. [Abstract] [Full Text] [PDF]  

Deepak Haikerwal, Anthony M. Dart, Peter J. Little, and David M. Kaye
Identification of a Novel, Inhibitory Action of Amiodarone on Vesicular Monoamine Transport
J Pharmacol Exp Ther 1999 288: 834-837. [Abstract] [Full Text] [PDF]  

Robin V. Searles, Vladimir Shikher, Carey D. Balaban, and Walter B. Severs
Timolol Effects on Aqueous Humor Dynamics in Eyes of Anesthetized Rats
J Pharmacol Exp Ther 1999 288: 838-842. [Abstract] [Full Text] [PDF]  

Koji Tada, Kimihiro Kasamo, Naoki Ueda, Tadashi Suzuki, Takuya Kojima, and Koichi Ishikawa
Anxiolytic 5-Hydroxytryptamine1A Agonists Suppress Firing Activity of Dorsal Hippocampus CA1 Pyramidal Neurons through a Postsynaptic Mechanism: Single-Unit Study in Unanesthetized, Unrestrained Rats
J Pharmacol Exp Ther 1999 288: 843-848. [Abstract] [Full Text] [PDF]  

Yuko Mizushima, Yukio Amano, Hiroshi Kitagawa, and Kenji Ogata
Oral Administration of Leflunomide (HWA486) Results in Prominent Suppression of Immunoglobulin E Formation in a Rat Type 1 Allergy Model
J Pharmacol Exp Ther 1999 288: 849-857. [Abstract] [Full Text] [PDF]  

Majed Khalifa, Benoit Drolet, Pascal Daleau, Christophe Lefez, Marcel Gilbert, Sylvain Plante, Gilles E. O'Hara, Onil Gleeton, Bettina A. Hamelin, and Jacques Turgeon
Block of Potassium Currents in Guinea Pig Ventricular Myocytes and Lengthening of Cardiac Repolarization in Man by the Histamine H1 Receptor Antagonist Diphenhydramine
J Pharmacol Exp Ther 1999 288: 858-865. [Abstract] [Full Text] [PDF]  

Subhash C. Pandey, Daolong Zhang, Navdha Mittal, and Deepak Nayyar
Potential Role of the Gene Transcription Factor Cyclic AMP-Responsive Element Binding Protein in Ethanol Withdrawal-Related Anxiety
J Pharmacol Exp Ther 1999 288: 866-878. [Abstract] [Full Text] [PDF]  

Meleik A. Hebert and Greg A. Gerhardt
Age-Related Changes in the Capacity, Rate, and Modulation of Dopamine Uptake within the Striatum and Nucleus Accumbens of Fischer 344 Rats: An In Vivo Electrochemical Study
J Pharmacol Exp Ther 1999 288: 879-887. [Abstract] [Full Text] [PDF]  

Kokichi Suzuki, Hiroshi Susaki, Satoshi Okuno, Harutami Yamada, Hiroshi K. Watanabe, and Yuichi Sugiyama
Specific Renal Delivery of Sugar-Modified Low-Molecular-Weight Peptides
J Pharmacol Exp Ther 1999 288: 888-897. [Abstract] [Full Text] [PDF]  

Shigeki Tazawa, Tokio Nakane, and Shigetoshi Chiba
Angiotensin II Type 1 Receptor Blockade Prevents Up-Regulation of Angiotensin II Type 1A Receptors in Rat Injured Artery
J Pharmacol Exp Ther 1999 288: 898-904. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Scheme for the pharmacological determination of the receptor selectivity of heroin given i.c.v. based on inhibition of descending (serotonergic, GABAergic, noradrenergic) systems. The various antagonists with dose and route of administration are given in the ellipse, and the lines connecting downward indicate the progression of the analyses. The inbred strains, which were ultimately classified as groups A, B, and C, are indicated in the rectangles. See the article in this issue by Rady et al., p.438.


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