ARTICLES:

Ying-Fu Su, Robert W. McNutt, and Kwen-Jen Chang

Delta-Opioid Ligands Reverse Alfentanil-Induced Respiratory Depression but Not Antinociception
J Pharmacol Exp Ther 1998 287: 815-823. [Abstract] [Full Text] [PDF]  

Michel F. Rossier, Eric A. Ertel, Michel B. Vallotton, and Alessandro M. Capponi

Inhibitory Action of Mibefradil on Calcium Signaling and Aldosterone Synthesis in Bovine Adrenal Glomerulosa Cells
J Pharmacol Exp Ther 1998 287: 824-831. [Abstract] [Full Text] [PDF]  

Moez Rekik, Michel Delvaux, Jacques Frexinos, and Lionel Bueno

Role of Vasoactive Intestinal Polypeptide in the Adaptation of Intestinal Smooth Muscle Cells to Mechanical Distension
J Pharmacol Exp Ther 1998 287: 832-838. [Abstract] [Full Text] [PDF]  

Michael F. O'Neill, Caroline A. Hicks, Gillian Shaw, Tirumaran Parameswaran, Geraldine P. Cardwell, and Michael J. O'Neill

Effects of 5-Hydroxytryptamine₂ Receptor Antagonism on the Behavioral Activation and Immediate Early Gene Expression Induced by Dizocilpine
J Pharmacol Exp Ther 1998 287: 839-846. [Abstract] [Full Text] [PDF]  

Peter Curzon, Arthur L. Nikkel, Anthony W. Bannon, Stephen P. Arneric, and Michael W. Decker

Differences Between the Antinociceptive Effects of the Cholinergic Channel Activators A-85380 and (±)-Epibatidine in Rats
J Pharmacol Exp Ther 1998 287: 847-853. [Abstract] [Full Text] [PDF]  

Sebastián Videla, Ana García-Lafuente, María Antolín, Jaime Vilaseca, Francisco Guarner, Ernesto Crespo, Guadalupe González, Antonio Salas, and Juan R. Malagelada

Antitumor Necrosis Factor Therapy in Rat Chronic Granulomatous Colitis: Critical Dose-Timing Effects on Outcome
J Pharmacol Exp Ther 1998 287: 854-859. [Abstract] [Full Text] [PDF]  

Yoshitaka Yamamura, Shigeki Nakamura, Shuji Itoh, Takahiro Hirano, Toshiyuki Onogawa, Tatsuya Yamashita, Yoshihisa Yamada, Kenji Tsujimae, Masashi Aoyama, Kounori Kotosai, Hidenori Ogawa, Hiroshi Yamashita, Kazumi Kondo, Michiaki Tominaga, Gozoh Tsujimoto, and Toyoki Mori

OPC-41061, a Highly Potent Human Vasopressin V₂-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats
J Pharmacol Exp Ther 1998 287: 860-867. [Abstract] [Full Text] [PDF]  

David C. McMillan, Charles B. Jensen, and David J. Jollow

Role of Lipid Peroxidation in Dapsone-Induced Hemolytic Anemia
J Pharmacol Exp Ther 1998 287: 868-876. [Abstract] [Full Text] [PDF]  

Xiao-Ke Liu, Alexander Katchman, Steven N. Ebert, and Raymond L. Woosley

The Antiestrogen Tamoxifen Blocks the Delayed Rectifier Potassium Current, I_Kr, in Rabbit Ventricular Myocytes
J Pharmacol Exp Ther 1998 287: 877-883. [Abstract] [Full Text] [PDF]  

D. W. Bonhaus, L. K. Chang, J. Kwan, and G. R. Martin

Dual Activation and Inhibition of Adenylyl Cyclase by Cannabinoid Receptor Agonists: Evidence for Agonist-Specific Trafficking of Intracellular Responses
J Pharmacol Exp Ther 1998 287: 884-888. [Abstract] [Full Text] [PDF]  

Saleh Abu-Raya, Eugenia Bloch-Shilderman, Esther Shohami, Victoria Trembovler, Yechiel Shai, Joseph Weidenfeld, Saul Yedgar, Yehuda Gutman, and Philip Lazarovici

Pardaxin, a New Pharmacological Tool to Stimulate the Arachidonic Acid Cascade in PC12 Cells
J Pharmacol Exp Ther 1998 287: 889-896. [Abstract] [Full Text] [PDF]  

Jiro Nakamura, Naoki Koh, Fumihiko Sakakibara, Yoji Hamada, Tomohiro Hara, Hiromitsu Sasaki, Sadao Chaya, Taku Komori, Eitaro Nakashima, Keiko Naruse, Koichi Kato, Naohide Takeuchi, Yasuhide Kasuya, and Nigishi Hotta

Polyol Pathway Hyperactivity Is Closely Related to Carnitine Deficiency in the Pathogenesis of Diabetic Neuropathy of Streptozotocin-Diabetic Rats
J Pharmacol Exp Ther 1998 287: 897-902. [Abstract] [Full Text] [PDF]  

Christina Vafeas, Paul A. Mieyal, Ferdinando Urbano, John R. Falck, Kamlesh Chauhan, Michael Berman, and Michal Laniado Schwartzman

Hypoxia Stimulates the Synthesis of Cytochrome P450-Derived Inflammatory Eicosanoids in Rabbit Corneal Epithelium
J Pharmacol Exp Ther 1998 287: 903-910. [Abstract] [Full Text] [PDF]  

David E. Burgio, Michael P. Gosl, and and Patrick J. McNamara

Effects of P-glycoprotein Modulators on Etoposide Elimination and Central Nervous System Distribution
J Pharmacol Exp Ther 1998 287: 911-917. [Abstract] [Full Text] [PDF]  

Edwin M. Meyer, Alexander Kuryatov, Volodymyr Gerzanich, Jon Lindstrom, and Roger L. Papke

Analysis of 3-(4-Hydroxy, 2-Methoxybenzylidene)Anabaseine Selectivity and Activity at Human and Rat Alpha-7 Nicotinic Receptors
J Pharmacol Exp Ther 1998 287: 918-925. [Abstract] [Full Text] [PDF]  

Zaichuan Mi and Edwin K. Jackson

Evidence for an Endogenous cAMP-Adenosine Pathway in the Rat Kidney
J Pharmacol Exp Ther 1998 287: 926-930. [Abstract] [Full Text] [PDF]  

Thomas E. N. Jonassen, Jørgen Søberg Petersen, Anne-Mette Sørensen, Frederik Andreasen, and Sten Christensen

Aldosterone Receptor Blockade Inhibits Increased Furosemide-Sensitive Sodium Reabsorption in Rats with Liver Cirrhosis
J Pharmacol Exp Ther 1998 287: 931-936. [Abstract] [Full Text] [PDF]  

Zhong You Wei and Sandra C. Roerig

Spinal Morphine/Clonidine Antinociceptive Synergism is Regulated by Protein Kinase C, but not Protein Kinase A Activity
J Pharmacol Exp Ther 1998 287: 937-943. [Abstract] [Full Text] [PDF]  

A. R. Villalobos and E. J. Braun

Substrate Specificity of Organic Cation/H⁺ Exchange in Avian Renal Brush-Border Membranes
J Pharmacol Exp Ther 1998 287: 944-951. [Abstract] [Full Text] [PDF]  

Angelo A. Izzo, Marcello Costa, Nicola Mascolo, and Francesco Capasso

The Role of Histamine H₁, H₂ and H₃ Receptors on Enteric Ascending Synaptic Transmission in the Guinea Pig Ileum
J Pharmacol Exp Ther 1998 287: 952-957. [Abstract] [Full Text] [PDF]  

Neal L. Benowitz, Shoshana Zevin, and Peyton Jacob III

Suppression of Nicotine Intake During Ad Libitum Cigarette Smoking by High-Dose Transdermal Nicotine
J Pharmacol Exp Ther 1998 287: 958-962. [Abstract] [Full Text] [PDF]  

Saeheum Song, Hiroshi Suzuki, Tetsuya Terasaki, Michel Lemaire, and Yuichi Sugiyama

Modulation of the Tumor Disposition of Vinca Alkaloids by PSC 833 In Vitro and In Vivo
J Pharmacol Exp Ther 1998 287: 963-968. [Abstract] [Full Text] [PDF]  

Pietro Ghezzi, Gabriella Melillo, Cristina Meazza, Silvano Sacco, Luigi Pellegrini, Cinzia Asti, Stefano Porzio, Antonello Marullo, Vilma Sabbatini, Gianfranco Caselli, and Riccardo Bertini

Differential Contribution of R and S Isomers in Ketoprofen Anti-inflammatory Activity: Role of Cytokine Modulation
J Pharmacol Exp Ther 1998 287: 969-974. [Abstract] [Full Text] [PDF]  

Daniela M. Gentile, Carole H. J. Verhoeven, Tsutomu Shimada, and David J. Back

The Role of CYP2C in the In Vitro Bioactivation of the Contraceptive Steroid Desogestrel
J Pharmacol Exp Ther 1998 287: 975-982. [Abstract] [Full Text] [PDF]  

Edward F. Domino, Lisong Ni, Huilei Zhang, Yasuko Kohno, and Masashi Sasa

Effects of Pramipexole on Contraversive Rotation and Functional Motor Impairments in 1-Methyl-4-phenyl1,2,3,6-tetrahydropyridine-Induced Chronic Hemiparkinsonian Monkeys
J Pharmacol Exp Ther 1998 287: 983-987. [Abstract] [Full Text] [PDF]  

David C. Underwood, Steven Bochnowicz, Ruth R. Osborn, Charles J. Kotzer, Mark A. Luttmann, Douglas W.P. Hay, Peter D. Gorycki, Siegfried B. Christensen, and Theodore J. Torphy

Antiasthmatic Activity of the Second-Generation Phosphodiesterase 4 (PDE4) Inhibitor SB 207499 (Ariflo) in the Guinea Pig
J Pharmacol Exp Ther 1998 287: 988-995. [Abstract] [Full Text] [PDF]  

Mark E. Anderson, Andrew P. Braun, Yuejin Wu, Tong Lu, Yiming Wu, Howard Schulman, and Ruey J. Sung

KN-93, an Inhibitor of Multifunctional Ca⁺⁺/Calmodulin-Dependent Protein Kinase, Decreases Early Afterdepolarizations in Rabbit Heart
J Pharmacol Exp Ther 1998 287: 996-1006. [Abstract] [Full Text] [PDF]  

Kaitlin E. Browman, Aldo Badiani, and Terry E. Robinson

Modulatory Effect of Environmental Stimuli on the Susceptibility to Amphetamine Sensitization: A Dose-Effect Study in Rats
J Pharmacol Exp Ther 1998 287: 1007-1014. [Abstract] [Full Text] [PDF]  

Jeffrey L. Calton, Wilkie A. Wilson, and Scott D. Moore

Magnesium-Dependent Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Synaptic Transmission by Ethanol
J Pharmacol Exp Ther 1998 287: 1015-1019. [Abstract] [Full Text] [PDF]  

Richard J. Servatius, John E. Ottenweller, Dawn Beldowicz, Weidun Guo, Guanping Zhu, and Benjamin H. Natelson

Persistently Exaggerated Startle Responses in Rats Treated with Pyridostigmine Bromide
J Pharmacol Exp Ther 1998 287: 1020-1028. [Abstract] [Full Text] [PDF]  

Michael R. Brandt and Charles P. France

Chronic l-Alpha Acetylmethadol in Rhesus Monkeys: Discriminative Stimulus and Other Behavioral Measures of Dependence and Withdrawal
J Pharmacol Exp Ther 1998 287: 1029-1037. [Abstract] [Full Text] [PDF]  

Murielle Rinaldi-Carmona, Anne Le Duigou, Didier Oustric, Francis Barth, Monsif Bouaboula, Pierre Carayon, Pierre Casellas, and Gérard Le Fur

Modulation of CB1 Cannabinoid Receptor Functions after a Long-Term Exposure to Agonist or Inverse Agonist in the Chinese Hamster Ovary Cell Expression System
J Pharmacol Exp Ther 1998 287: 1038-1047. [Abstract] [Full Text] [PDF]  

Basilia Zingarelli, Salvatore Cuzzocrea, Csaba Szabó, and Andrew L. Salzman

Mercaptoethylguanidine, a Combined Inhibitor of Nitric Oxide Synthase and Peroxynitrite Scavenger, Reduces Trinitrobenzene Sulfonic Acid-Induced Colonic Damage in Rats
J Pharmacol Exp Ther 1998 287: 1048-1055. [Abstract] [Full Text] [PDF]  

Kazuko Sagawa, Debra C. DuBois, Richard R. Almon, Heini Murer, and Marilyn E. Morris

Cellular Mechanisms of Renal Adaptation of Sodium Dependent Sulfate Cotransport to Altered Dietary Sulfate in Rats
J Pharmacol Exp Ther 1998 287: 1056-1062. [Abstract] [Full Text] [PDF]  

Masahiro Nishio, Yasuo Watanabe, and Hiroyoshi Hidaka

HMN-1180, a Small Molecule Inhibitor of Neuronal Nitric Oxide Synthase
J Pharmacol Exp Ther 1998 287: 1063-1067. [Abstract] [Full Text] [PDF]  

Margarita M. Puig and Olga Pol

Peripheral Effects of Opioids in a Model of Chronic Intestinal Inflammation in Mice
J Pharmacol Exp Ther 1998 287: 1068-1075. [Abstract] [Full Text] [PDF]  

Kristen A. Keefe and Amy C. Adams

Differential Effects of N-Methyl-D-Aspartate Receptor Blockade on Eticlopride-Induced Immediate Early Gene Expression in the Medial and Lateral Striatum
J Pharmacol Exp Ther 1998 287: 1076-1083. [Abstract] [Full Text] [PDF]  

Yasuo Matsumura, Manabu Nishiura, Shougo Deguchi, Norio Hashimoto, Toshikazu Ogawa, and Rumi Seo

Protective Effect of FK409, a Spontaneous Nitric Oxide Releaser, on Ischemic Acute Renal Failure in Rats
J Pharmacol Exp Ther 1998 287: 1084-1091. [Abstract] [Full Text] [PDF]  

Kazuko Sagawa, Lisa Jo Benincosa, Heini Murer, and Marilyn E. Morris

Ibuprofen-Induced Changes in Sulfate Renal Transport
J Pharmacol Exp Ther 1998 287: 1092-1097. [Abstract] [Full Text] [PDF]  

Gisa Tiegs, Sabine Küsters, Gerald Künstle, Hannes Hentze, Alexandra K. Kiemer, and Albrecht Wendel

Ebselen Protects Mice Against T Cell-Dependent, TNF-Mediated Apoptotic Liver Injury¹
J Pharmacol Exp Ther 1998 287: 1098-1104. [Abstract] [Full Text] [PDF]  

Seung H. Han, Sung Su Yea, Young J. Jeon, Kyu-H. Yang, and Norbert E. Kaminski

Transforming Growth Factor-Beta 1 (TGF-1) Promotes IL-2 mRNA Expression Through the Up-regulation of NF-B, AP-1 and NF-AT in EL4 Cells
J Pharmacol Exp Ther 1998 287: 1105-1112. [Abstract] [Full Text] [PDF]  

Rebecca S. Marcus, Michael P. Holsapple, and Norbert E. Kaminski

Lipopolysaccharide Activation of Murine Splenocytes and Splenic B Cells Increased the Expression of Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Receptor Nuclear Translocator
J Pharmacol Exp Ther 1998 287: 1113-1118. [Abstract] [Full Text] [PDF]  

Joanne J. Chen, Michael R. Vasko, Xiaoping Wu, Theodora P. Staeva, Melvyn Baez, John M. Zgombick, and David L. Nelson

Multiple Subtypes of Serotonin Receptors Are Expressed in Rat Sensory Neurons in Culture
J Pharmacol Exp Ther 1998 287: 1119-1127. [Abstract] [Full Text] [PDF]  

Louise M. Winn, Perry M. Kim, and Peter G. Wells

Investigation of the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone for In Vivo and In Vitro Murine Embryopathy and Embryonic ras Mutations
J Pharmacol Exp Ther 1998 287: 1128-1135. [Abstract] [Full Text] [PDF]  

T. S. Roy, J. E. Andrews, F. J. Seidler, and T. A. Slotkin

Nicotine Evokes Cell Death in Embryonic Rat Brain during Neurulation
J Pharmacol Exp Ther 1998 287: 1136-1144. [Abstract] [Full Text] [PDF]  

ERRATA:

Correction for vol. 285, p. 1084
J Pharmacol Exp Ther 1998 287: 1135. [Full Text]  

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