ARTICLES:

Nicoletta Galeotti, Carla Ghelardini, and Alessandro Bartolini

Role of 5-HT₄ Receptors in the Mouse Passive Avoidance Test
J Pharmacol Exp Ther 1998 286: 1115-1121. [Abstract] [Full Text] [PDF]  

Rolf Gebhardt

Inhibition of Cholesterol Biosynthesis in Primary Cultured Rat Hepatocytes by Artichoke (Cynara scolymus L.) Extracts
J Pharmacol Exp Ther 1998 286: 1122-1128. [Abstract] [Full Text] [PDF]  

X.-P. Huang, F. E. Williams, S. M. Peseckis, and W. S. Messer Jr.

Pharmacological Characterization of Human m1 Muscarinic Acetylcholine Receptors with Double Mutations at the Junction of TM VI and the Third Extracellular Domain
J Pharmacol Exp Ther 1998 286: 1129-1139. [Abstract] [Full Text] [PDF]  

Tsugunobu Andoh, Tetsuro Nagasawa, Masamichi Satoh, and Yasushi Kuraishi

Substance P Induction of Itch-Associated Response Mediated by Cutaneous NK₁ Tachykinin Receptors in Mice
J Pharmacol Exp Ther 1998 286: 1140-1145. [Abstract] [Full Text] [PDF]  

David Fulton and John Quilley

Evidence against Anandamide as the Hyperpolarizing Factor Mediating the Nitric Oxide-Independent Coronary Vasodilator Effect of Bradykinin in the Rat
J Pharmacol Exp Ther 1998 286: 1146-1151. [Abstract] [Full Text] [PDF]  

Lena Brynne, Mats O. Karlsson, and Lennart K. Paalzow

Concentration-Effect Relationship of l-Propranolol and Metoprolol in Spontaneous Hypertensive Rats after Exercise-Induced Tachycardia
J Pharmacol Exp Ther 1998 286: 1152-1158. [Abstract] [Full Text] [PDF]  

Norberto Aguirre, Meritxell Barrionuevo, Berta Lasheras, and Joaquín Del Río

The Role of Dopaminergic Systems in the Perinatal Sensitivity to 3,4-Methylenedioxymethamphetamine-Induced Neurotoxicity in Rats
J Pharmacol Exp Ther 1998 286: 1159-1165. [Abstract] [Full Text] [PDF]  

Remco L. A.  de Vrueh, Philip L. Smith, and Chao-Pin Lee

Transport of L-Valine-Acyclovir Via the Oligopeptide Transporter In The Human Intestinal Cell Line, Caco-2
J Pharmacol Exp Ther 1998 286: 1166-1170. [Abstract] [Full Text] [PDF]  

R. C. Pierce, E. A. Quick, D. C. Reeder, Z. R. Morgan, and P. W. Kalivas

Calcium-Mediated Second Messengers Modulate the Expression of Behavioral Sensitization to Cocaine
J Pharmacol Exp Ther 1998 286: 1171-1176. [Abstract] [Full Text] [PDF]  

Liang Zhang, Yu Zhang, and Richard Wennberg

Multiple Actions of Methohexital on Hippocampal CA1 and Cortical Neurons of Rat Brain Slices
J Pharmacol Exp Ther 1998 286: 1177-1182. [Abstract] [Full Text] [PDF]  

Sabata Pierno, Annamaria De Luca, Claudia Camerino, Ryan J. Huxtable, and Diana Conte Camerino

Chronic Administration of Taurine to Aged Rats Improves the Electrical and Contractile Properties of Skeletal Muscle Fibers
J Pharmacol Exp Ther 1998 286: 1183-1190. [Abstract] [Full Text] [PDF]  

Miklos Gellai, George F. Schreiner, Robert R. Ruffolo Jr., Tracey Fletcher, Robin DeWolf, and David P. Brooks

CVT-124, a Novel Adenosine A₁ Receptor Antagonist with Unique Diuretic Activity
J Pharmacol Exp Ther 1998 286: 1191-1196. [Abstract] [Full Text] [PDF]  

James P. Zacny, Joanna L. Hill, Matthew L. Black, and Parvine Sadeghi

Comparing the Subjective, Psychomotor and Physiological Effects of Intravenous Pentazocine and Morphine in Normal Volunteers
J Pharmacol Exp Ther 1998 286: 1197-1207. [Abstract] [Full Text] [PDF]  

George P. Thomas, Stephen M. Sims, Michael A. Cook, and Morris Karmazyn

Hydrogen Peroxide-Induced Stimulation of L-Type Calcium Current in Guinea Pig Ventricular Myocytes and Its Inhibition by Adenosine A1 Receptor Activation
J Pharmacol Exp Ther 1998 286: 1208-1214. [Abstract] [Full Text] [PDF]  

Volker Vallon, Margitta Albinus, and Doreen Blach

Effect of K_ATP Channel Blocker U37883A on Renal Function in Experimental Diabetes Mellitus in Rats
J Pharmacol Exp Ther 1998 286: 1215-1221. [Abstract] [Full Text] [PDF]  

Kenji Hosoda, Toku Takahashi, Masayuki A. Fujino, and Chung Owyang

Inhibitory Effects of Nitric Oxide Donors on Nitric Oxide Synthesis in Rat Gastric Myenteric Plexus
J Pharmacol Exp Ther 1998 286: 1222-1230. [Abstract] [Full Text] [PDF]  

Luigi Pulvirenti, Claudia Balducci, Marla Piercy, and George F. Koob

Characterization of the Effects of the Partial Dopamine Agonist Terguride on Cocaine Self-Administration in the Rat
J Pharmacol Exp Ther 1998 286: 1231-1238. [Abstract] [Full Text] [PDF]  

Jianming Dong, Claude de Montigny, and Pierre Blier

Full Agonistic Properties of Bay x 3702 on Presynaptic and Postsynaptic 5-HT_1A Receptors Electrophysiological Studies in the Rat Hippocampus and Dorsal Raphe.
J Pharmacol Exp Ther 1998 286: 1239-1247. [Abstract] [Full Text] [PDF]  

Gerd Luippold and Bernd Mühlbauer

Dopamine D₂ Receptors Mediate Glomerular Hyperfiltration Due To Amino Acids
J Pharmacol Exp Ther 1998 286: 1248-1252. [Abstract] [Full Text] [PDF]  

Sean Ekins, Mark Vandenbranden, Barbara J. Ring, Jennifer S. Gillespie, Tian J. Yang, Harry V. Gelboin, and Steven A. Wrighton

Further Characterization of the Expression in Liver and Catalytic Activity of CYP2B6
J Pharmacol Exp Ther 1998 286: 1253-1259. [Abstract] [Full Text] [PDF]  

Ivan O. Medvedev, Olga A. Dravolina, and Anton Y. Bespalov

Effects of N-Methyl-D-Aspartate Receptor Antagonists on Discriminative Stimulus Effects of Naloxone in Morphine-Dependent Rats Using the Y-Maze Drug Discrimination Paradigm
J Pharmacol Exp Ther 1998 286: 1260-1268. [Abstract] [Full Text] [PDF]  

Zuoyi Shao, Ian R. Mellor, Matthew J. Brierley, John Harris, and Peter N. R. Usherwood

Potentiation and Inhibition of Nicotinic Acetylcholine Receptors by Spermine in the TE671 Human Muscle Cell Line
J Pharmacol Exp Ther 1998 286: 1269-1276. [Abstract] [Full Text] [PDF]  

Shaker A. Mousa, Jeffrey M. Bozarth, William Lorelli, Mark S. Forsythe, Martin J. M. C. Thoolen, Andrew M. Slee, Thomas M. Reilly, and Paul A. Friedman

Antiplatelet Efficacy of XV459, A Novel Nonpeptide Platelet GPIIb/IIIa Antagonist: Comparative Platelet Binding Profiles with c7E3
J Pharmacol Exp Ther 1998 286: 1277-1284. [Abstract] [Full Text] [PDF]  

A. E. Mutlib and J. T. Klein

Application of Liquid Chromatography/Mass Spectrometry in Accelerating the Identification of Human Liver Cytochrome P450 Isoforms Involved in the Metabolism of Iloperidone
J Pharmacol Exp Ther 1998 286: 1285-1293. [Abstract] [Full Text] [PDF]  

Takashi Kawashiro, Kouwa Yamashita, Xue-Jun Zhao, Eriko Koyama, Masayoshi Tani, Kan Chiba, and Takashi Ishizaki

A Study on the Metabolism of Etoposide and Possible Interactions with Antitumor or Supporting Agents by Human Liver Microsomes
J Pharmacol Exp Ther 1998 286: 1294-1300. [Abstract] [Full Text] [PDF]  

Sandra P. Welch, John W. Huffman, and John Lowe

Differential Blockade of the Antinociceptive Effects of Centrally Administered Cannabinoids by SR141716A
J Pharmacol Exp Ther 1998 286: 1301-1308. [Abstract] [Full Text] [PDF]  

L. Ermert, M. Ermert, A. Althoff, M. Merkle, F. Grimminger, and W. Seeger

Vasoregulatory Prostanoid Generation Proceeds Via Cyclooxygenase-2 in Noninflamed Rat Lungs
J Pharmacol Exp Ther 1998 286: 1309-1314. [Abstract] [Full Text] [PDF]  

Gloria Segarra, Pascual Medina, Cristina Domenech, José M. Vila, Juan B. Martínez-León, Martín Aldasoro, and Salvador Lluch

Role of Vasopressin on Adrenergic Neurotransmission in Human Penile Blood Vessels
J Pharmacol Exp Ther 1998 286: 1315-1320. [Abstract] [Full Text] [PDF]  

Tomio Okamura, Hideyuki Fujioka, Kazuhide Ayajiki, and Noboru Toda

Modifications by Superoxide-Generating Agent, Neurotransmitters and Neuromodulators of Nitroxidergic Nerve Function in Monkey Cerebral Arteries
J Pharmacol Exp Ther 1998 286: 1321-1325. [Abstract] [Full Text] [PDF]  

Samantha M. South and Maree T. Smith

Apparent Insensitivity of the Hotplate Latency Test for Detection of Antinociception Following Intraperitoneal, Intravenous or Intracerebroventricular M6G Administration to Rats
J Pharmacol Exp Ther 1998 286: 1326-1332. [Abstract] [Full Text] [PDF]  

Trisha Burke, Stephanie Lee, Peter J. Ferguson, and James R. Hammond

Interaction of 2',2'-Difluorodeoxycytidine (Gemcitabine) and Formycin B with the Na⁺-Dependent and -Independent Nucleoside Transporters of Ehrlich Ascites Tumor Cells
J Pharmacol Exp Ther 1998 286: 1333-1340. [Abstract] [Full Text] [PDF]  

Mark J. Millan, Alain Gobert, Adrian Newman-Tancredi, Valérie Audinot, Françoise Lejeune, Jean-Michel Rivet, Didier Cussac, Jean-Paul Nicolas, Olivier Muller, and Gilbert Lavielle

S 16924 ((R)-2-{1-[2-(2,3-Dihydro-Benzo[1,4] Dioxin-5-Yloxy)-Ethyl]-Pyrrolidin-3yl}-1-(4-Fluoro-Phenyl)-Ethanone), a Novel, Potential Antipsychotic with Marked Serotonin (5-HT)_1A Agonist Properties: I. Receptorial and Neurochemical Profile in Comparison with Clozapine and Haloperidol
J Pharmacol Exp Ther 1998 286: 1341-1355. [Abstract] [Full Text] [PDF]  

Mark J. Millan, Rudy Schreiber, Anne Dekeyne, Jean-Michel Rivet, Karin Bervoets, Michaelis Mavridis, Claude Sebban, Sophie Maurel-Remy, Adrian Newman-Tancredi, Michael Spedding, Olivier Muller, Gilbert Lavielle, and Mauricette Brocco

S 16924 ((R)-2-{1-[2-(2,3-Dihydro-Benzo[1,4] Dioxin-5-Yloxy)-Ethyl]-Pyrrolidin-3yl}-1-(4-Fluoro-Phenyl)-Ethanone), a Novel, Potential Antipsychotic with Marked Serotonin (5-HT)_1A Agonist Properties: II. Functional Profile in Comparison to Clozapine and Haloperidol
J Pharmacol Exp Ther 1998 286: 1356-1373. [Abstract] [Full Text] [PDF]  

Stephan Winter and Michael Weller

Potentiation of CD95L-Induced Apoptosis of Human Malignant Glioma Cells by Topotecan Involves Inhibition of RNA Synthesis but Not Changes in CD95 or CD95L Protein Expression
J Pharmacol Exp Ther 1998 286: 1374-1382. [Abstract] [Full Text] [PDF]  

Jun-Ichi Shigeta, Satoru Takahashi, and Susumu Okabe

Role of Cyclooxygenase-2 in the Healing of Gastric Ulcers in Rats
J Pharmacol Exp Ther 1998 286: 1383-1390. [Abstract] [Full Text] [PDF]  

Hikaru Yabuuchi, Ikumi Tamai, Kyoko Morita, Tomoko Kouda, Ken-Ichi Miyamoto, Eiji Takeda, and Akira Tsuji

Hepatic Sinusoidal Membrane Transport of Anionic Drugs Mediated by Anion Transporter Npt1
J Pharmacol Exp Ther 1998 286: 1391-1396. [Abstract] [Full Text] [PDF]  

Juan C. Leza, Eduardo Salas, Grzegorz Sawicki, James C. Russell, and Marek W. Radomski

The Effects of Stress on Homeostasis in JCR-LA-cp Rats: The Role of Nitric Oxide
J Pharmacol Exp Ther 1998 286: 1397-1403. [Abstract] [Full Text] [PDF]  

Amber L. Pond, Howard W. Chambers, Cody P. Coyne, and Janice E. Chambers

Purification of Two Rat Hepatic Proteins with A-Esterase Activity Toward Chlorpyrifos-Oxon and Paraoxon
J Pharmacol Exp Ther 1998 286: 1404-1411. [Abstract] [Full Text] [PDF]  

Virginia Tancredi, Margherita D'Antuono, Astrid Nehlig, and Massimo Avoli

Modulation of Epileptiform Activity by Adenosine A1 Receptor-Mediated Mechanisms in the Juvenile Rat Hippocampus
J Pharmacol Exp Ther 1998 286: 1412-1419. [Abstract] [Full Text] [PDF]  

Li Zeng, Songzhu An, and Edward J. Goetzl

EP₄/EP₂ Receptor-Specific Prostaglandin E₂ Regulation of Interleukin-6 Generation by Human HSB.2 Early T Cells
J Pharmacol Exp Ther 1998 286: 1420-1426. [Abstract] [Full Text] [PDF]  

Nobuhiko Miura, Masahiko Satoh, Nobumasa Imura, and Akira Naganuma

Protective Effect of Bismuth Nitrate Against Injury to the Bone Marrow by -Irradiation in Mice: Possible Involvement of Induction of Metallothionein Synthesis
J Pharmacol Exp Ther 1998 286: 1427-1430. [Abstract] [Full Text] [PDF]  

Stephanie W. Watts, Jennifer A. Florian, and Kimberly M. Monroe

Dissociation of Angiotensin II-Stimulated Activation of Mitogen-Activated Protein Kinase Kinase from Vascular Contraction
J Pharmacol Exp Ther 1998 286: 1431-1438. [Abstract] [Full Text] [PDF]  

Annice E. Kim, Jay M. Dintaman, David S. Waddell, and Jeffrey A. Silverman

Saquinavir, an HIV Protease Inhibitor, Is Transported by P-Glycoprotein
J Pharmacol Exp Ther 1998 286: 1439-1445. [Abstract] [Full Text] [PDF]  

H. A. Baghdoyan, R. Lydic, and M. A. Fleegal

M2 Muscarinic Autoreceptors Modulate Acetylcholine Release in the Medial Pontine Reticular Formation
J Pharmacol Exp Ther 1998 286: 1446-1452. [Abstract] [Full Text] [PDF]  

Heinz Gögelein, Jens Hartung, Heinrich C. Englert, and Bernward A. Schölkens

HMR 1883, a Novel Cardioselective Inhibitor of the ATP-Sensitive Potassium Channel. Part I: Effects on Cardiomyocytes, Coronary Flow and Pancreatic -Cells
J Pharmacol Exp Ther 1998 286: 1453-1464. [Abstract] [Full Text] [PDF]  

George E. Billman, Heinrich C. Englert, and Bernward A. Schölkens

HMR 1883, a Novel Cardioselective Inhibitor of the ATP-Sensitive Potassium Channel. Part II: Effects on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia in Conscious Dogs
J Pharmacol Exp Ther 1998 286: 1465-1473. [Abstract] [Full Text] [PDF]  

Theresa M. Cabrera-Vera and George Battaglia

Prenatal Exposure to Fluoxetine (Prozac) Produces Site-Specific and Age-Dependent Alterations in Brain Serotonin Transporters in Rat Progeny: Evidence from Autoradiographic Studies
J Pharmacol Exp Ther 1998 286: 1474-1481. [Abstract] [Full Text] [PDF]  

Shubhada Bhamre, Hoau-Yan Wang, and Eitan Friedman

Serotonin-Mediated Palmitoylation and Depalmitoylation of G Alpha Proteins in Rat Brain Cortical Membranes
J Pharmacol Exp Ther 1998 286: 1482-1489. [Abstract] [Full Text] [PDF]  

Gordon C. Ibeanu, Joyce A. Goldstein, Urs Meyer, Simone Benhamou, Christine Bouchardy, Pierre Dayer, Burhan I. Ghanayem, and Joyce Blaisdell

Identification of New Human CYP2C19 Alleles (CYP2C19*6 and CYP2C19*2B) in a Caucasian Poor Metabolizer of Mephenytoin
J Pharmacol Exp Ther 1998 286: 1490-1495. [Abstract] [Full Text] [PDF]  

ERRATA:

Correction for vol. 285, p. 54
J Pharmacol Exp Ther 1998 286: 1495. [Full Text] [PDF]  

Correction for vol. 270, p. 1381
J Pharmacol Exp Ther 1998 286: 1496. [Full Text] [PDF]  

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