ANALGESIA AND DRUGS OF ABUSE:

Jinmin Zhu, Lai-Yi Luo, Guan-Fen Mao, Barrie Ashby, and Lee-Yuan Liu-Chen

Agonist-Induced Desensitization and Down-regulation of the Human Kappa Opioid Receptor Expressed in Chinese Hamster Ovary Cells
J Pharmacol Exp Ther 1998 285: 28-36. [Abstract] [Full Text] [PDF]  

C. Courteix, P. Bourget, F. Caussade, M. Bardin, F. Coudore, J. Fialip, and A. Eschalier

Is the Reduced Efficacy of Morphine in Diabetic Rats Caused by Alterations of Opiate Receptors or of Morphine Pharmacokinetics?
J Pharmacol Exp Ther 1998 285: 63-70. [Abstract] [Full Text] [PDF]  

Sharon L. Walsh, Rolley E. Johnson, Edward J. Cone, and George E. Bigelow

Intravenous and Oral l--Acetylmethadol: Pharmacodynamics and Pharmacokinetics in Humans
J Pharmacol Exp Ther 1998 285: 71-82. [Abstract] [Full Text] [PDF]  

Nadège Altier and Jane Stewart

Dopamine Receptor Antagonists in the Nucleus Accumbens Attenuate Analgesia Induced by Ventral Tegmental Area Substance P or Morphine and by Nucleus Accumbens Amphetamine
J Pharmacol Exp Ther 1998 285: 208-215. [Abstract] [Full Text] [PDF]  

Brian F. Thomas, Anne F. Gilliam, David F. Burch, Michael J. Roche, and Herbert H. Seltzman

Comparative Receptor Binding Analyses of Cannabinoid Agonists and Antagonists
J Pharmacol Exp Ther 1998 285: 285-292. [Abstract] [Full Text] [PDF]  

AUTONOMIC PHARMACOLOGY:

Hidehiro Kakizaki, Mitsuharu Yoshiyama, James R. Roppolo, August M. Booth, and William C. De Groat

Role of Spinal Glutamatergic Transmission in the Ascending Limb of the Micturition Reflex Pathway in the Rat
J Pharmacol Exp Ther 1998 285: 22-27. [Abstract] [Full Text] [PDF]  

Erhe Gao, David L. Snyder, Jay Roberts, Eitan Friedman, Guoping Cai, Amir Pelleg, and Joel Horwitz

Age-Related Decline in Beta Adrenergic and Adenosine A₁ Receptor Function in the Heart Are Attenuated by Dietary Restriction
J Pharmacol Exp Ther 1998 285: 186-192. [Abstract] [Full Text] [PDF]  

Ken-Ichi Hosoya, Yoshihide Horibe, Kwang-Jin Kim, and Vincent H. L. Lee

Carrier-Mediated Transport of N^G-Nitro-L-Arginine, a Nitric Oxide Synthase Inhibitor, in the Pigmented Rabbit Conjunctiva
J Pharmacol Exp Ther 1998 285: 223-227. [Abstract] [Full Text] [PDF]  

Paul M. Lundy, Thomas W. Sawyer, Brian T. H, and and Robert Frew

Effects of Bis(2-chloroethyl)sulfide on ATP Receptor-Mediated Responses of the Rat Vas Deferens: Possible Relationship to Cytotoxicity
J Pharmacol Exp Ther 1998 285: 299-306. [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Elise M. Weerts, Nancy A. Ator, Doreen M. Grech, and Roland R. Griffiths

Zolpidem Physical Dependence Assessed Across Increasing Doses Under a Once-Daily Dosing Regimen in Baboons
J Pharmacol Exp Ther 1998 285: 41-53. [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR PHARMACOLOGY:

Paul S. Pagel, Douglas A. Hettrick, Matthew W. Montgomery, Judy R. Kersten, Robert P. Steffen, and David C. Warltier

RSR13, a Synthetic Modifier of Hemoglobin-Oxygen Affinity, Enhances the Recovery of Stunned Myocardium in Anesthetized Dogs
J Pharmacol Exp Ther 1998 285: 1-8. [Abstract] [Full Text] [PDF]  

Angela Monopoli, Carlo Casati, Gianluca Lozza, Angelo Forlani, and Ennio Ongini

Cardiovascular Pharmacology of the A_2A Adenosine Receptor Antagonist, SCH 58261, in the Rat
J Pharmacol Exp Ther 1998 285: 9-15. [Abstract] [Full Text] [PDF]  

Junzhi Ji, Christina G. Benishin, and Peter K. T. Pang

Nitric Oxide Selectively Inhibits Intracellular Ca⁺⁺ Release Elicited by Inositol Trisphosphate but not Caffeine in Rat Vascular Smooth Muscle
J Pharmacol Exp Ther 1998 285: 16-21. [Abstract] [Full Text] [PDF]  

P. Ferrari, L. Torielli, M. Ferrandi, G. Padoani, L. Duzzi, M. Florio, F. Conti, P. Melloni, L. Vesci, N. Corsico, and G. Bianchi

PST2238: A New Antihypertensive Compound That Antagonizes the Long-Term Pressor Effect of Ouabain
J Pharmacol Exp Ther 1998 285: 83-94. [Abstract] [Full Text] [PDF]  

Elizabeth P. Baskin and Joseph J. Lynch Jr.

Differential Atrial versus Ventricular Activities of Class III Potassium Channel Blockers
J Pharmacol Exp Ther 1998 285: 135-142. [Abstract] [Full Text] [PDF]  

Joseph B. Thompson, Susan M. Wade, Jeffrey K. Harrison, Mina N. Salafranca, and Richard R. Neubig

Cotransfection of Second and Third Intracellular Loop Fragments Inhibit Angiotensin AT1a Receptor Activation of Phospholipase C in HEK-293 Cells
J Pharmacol Exp Ther 1998 285: 216-222. [Abstract] [Full Text] [PDF]  

Anne M. Gillis, Radzfel A. Geonzon, Heather J. Mathison, Ela Kulisz, Wanda M. Lester, and Henry J. Duff

The Effects of Barium, Dofetilide and 4-Aminopyridine (4-AP) on Ventricular Repolarization in Normal and Hypertrophied Rabbit Heart
J Pharmacol Exp Ther 1998 285: 262-270. [Abstract] [Full Text] [PDF]  

Rostislav Bychkov, Maik Gollasch, Tobias Steinke, Christian Ried, Friedrich C. Luft, and Hermann Haller

Calcium-Activated Potassium Channels and Nitrate-Induced Vasodilation in Human Coronary Arteries
J Pharmacol Exp Ther 1998 285: 293-298. [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR PHARMACOLOGY:

Shirley M. E. Wong, David L. Tauck, Eileen G. Fong, and Joan J. Kendig

Glutamate Receptor-Mediated Hyperexcitability after Ethanol Exposure in Isolated Neonatal Rat Spinal Cord
J Pharmacol Exp Ther 1998 285: 201-207. [Abstract] [Full Text] [PDF]  

Angela Wong, Shing Mei Hwang, Kyung Johanson, James Samanen, Donald Bennett, Scott W. Landvatter, Wenting Chen, J. Richard Heys, Fadia E. Ali, Thomas W. Ku, William Bondinell, Andrew J. Nichols, David A. Powers, and Jeffrey M. Stadel

Binding of [³H]-SK&F 107260 and [³H]-SB 214857 to Purified Integrin _IIb3: Evidence for a Common Binding Site for Cyclic Arginyl-Glycinyl-Aspartic Acid Peptides and Nonpeptides
J Pharmacol Exp Ther 1998 285: 228-235. [Abstract] [Full Text] [PDF]  

T. J. Searl and E. M. Silinsky

Increases in Acetylcholine Release Produced by Phorbol Esters Are Not Mediated by Protein Kinase C at Motor Nerve Endings
J Pharmacol Exp Ther 1998 285: 247-251. [Abstract] [Full Text] [PDF]  

Luc Marti, Nathalie Morin, Gemma Enrique-Tarancon, Danielle Prevot, Max Lafontan, Xavier Testar, Antonio Zorzano, and Christian Carpéné

Tyramine and Vanadate Synergistically Stimulate Glucose Transport in Rat Adipocytes by Amine Oxidase-Dependent Generation of Hydrogen Peroxide
J Pharmacol Exp Ther 1998 285: 342-349. [Abstract] [Full Text] [PDF]  

M. A. Varney, S. P. Rao, C. Jachec, C. Deal, S. D. Hess, L. P. Daggett, F.-F. Lin, E. C. Johnson, and G. Veliçelebi

Pharmacological Characterization of the Human Ionotropic Glutamate Receptor Subtype GluR3 Stably Expressed in Mammalian Cells
J Pharmacol Exp Ther 1998 285: 358-370. [Abstract] [Full Text] [PDF]  

Michael J. Marks, Kimberly W. Smith, and Allan C. Collins

Differential Agonist Inhibition Identifies Multiple Epibatidine Binding Sites in Mouse Brain
J Pharmacol Exp Ther 1998 285: 377-386. [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY/GENE THERAPY:

Shigehiro Ohdo, Naoko Arata, Taku Furukubo, Eiji Yukawa, Shun Higuchi, Shigeyuki Nakano, and Nobuya Ogawa

Chronopharmacology of Granulocyte Colony-Stimulating Factor in Mice
J Pharmacol Exp Ther 1998 285: 242-246. [Abstract] [Full Text] [PDF]  

DEVELOPMENTAL PHARMACOLOGY:

Tove Tuntland, Aleksandrs Odinecs, Connie Nosbisch, and Jashvant D. Unadkat

In Vivo Maternal-Fetal-Amniotic Fluid Pharmacokinetics of Zidovudine in the Pigtailed Macaque: Comparison of Steady-State and Single-Dose Regimens
J Pharmacol Exp Ther 1998 285: 54-62. [Abstract] [Full Text] [PDF]  

DRUG METABOLISM AND DISPOSITION:

T. J. Gillespie, A. Erenberg, S. Kim, J. Dong, J. E. Taylor, V. Hau, and T. P. Davis

Novel Somatostatin Analogs for the Treatment of Acromegaly and Cancer Exhibit Improved In Vivo Stability and Distribution
J Pharmacol Exp Ther 1998 285: 95-104. [Abstract] [Full Text] [PDF]  

M. Isabel Guillén, M. Teresa Donato, Ramiro Jover, José V. Castell, R. Fabra, R. Trullenque, and M. José Gómez-Lechón

Oncostatin M Down-regulates Basal and Induced Cytochromes P450 in Human Hepatocytes
J Pharmacol Exp Ther 1998 285: 127-134. [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL PHARMACOLOGY:

Myung-Gyu Choi, Michael Camilleri, Duane D. Burton, Steven Johnson, and Anthony Edmonds

Dose-Related Effects of N-Demethyl-N-Isopropyl-8,9-anhydroerythromycin A 6,9-hemiacetal on Gastric Emptying of Solids in Healthy Human Volunteers
J Pharmacol Exp Ther 1998 285: 37-40. [Abstract] [Full Text] [PDF]  

Gerhard J. Molderings, Kurt Donecker, Maria Burian, W. Alexander Simon, Detlev W. Schröder, and Manfred Göthert

Characterization of I₂ Imidazoline and  Binding Sites in the Rat and Human Stomach
J Pharmacol Exp Ther 1998 285: 170-177. [Abstract] [Full Text] [PDF]  

Xi-Long Zheng, Bernard Renaux, and Morley D. Hollenberg

Parallel Contractile Signal Transduction Pathways Activated by Receptors for Thrombin and Epidermal Growth Factor-Urogastrone in Guinea Pig Gastric Smooth Muscle: Blockade by Inhibitors of Mitogen-Activated Protein Kinase-Kinase and Phosphatidyl Inositol 3'-Kinase
J Pharmacol Exp Ther 1998 285: 325-334. [Abstract] [Full Text] [PDF]  

IMMUNOPHARMACOLOGY:

David S. Cissel, Paul F. Fraundorfer, and Michael A. Beaven

Thapsigargin-Induced Secretion Is Dependent on Activation of a Cholera Toxin-Sensitive and Phosphatidylinositol-3-kinase-Regulated Phospholipase D in a Mast Cell Line
J Pharmacol Exp Ther 1998 285: 110-118. [Abstract] [Full Text] [PDF]  

Giuliana Porro, Giorgio Bertolini, M. Antonietta Bonardi, Elena Giovanetti, Paola Lento, Flavio Leoni, Daniela Modena, Gianfranco Pavich, and Fabrizio Marcucci

Diaminic Carbonates, a New Class of Anti-inflammatory Compounds: Their Biological Characterization and Mode of Action
J Pharmacol Exp Ther 1998 285: 193-200. [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Yushan Wang and Thomas D. White

Effect of Protein Kinase C Activation on N-Methyl-D-Aspartate-Evoked Release of Adenosine and [³H]Norepinephrine from Rat Cortical Slices
J Pharmacol Exp Ther 1998 285: 105-109. [Abstract] [Full Text] [PDF]  

Åsa Malmberg, Åsa Mikaels, and Nina Mohell

Agonist and Inverse Agonist Activity at the Dopamine D₃ Receptor Measured by Guanosine 5'-[-Thio]Triphosphate-[³⁵S] Binding
J Pharmacol Exp Ther 1998 285: 119-126. [Abstract] [Full Text] [PDF]  

B.H.C. Westerink, P. Enrico, J. Feimann, and J.B. De Vries

The Pharmacology of Mesocortical Dopamine Neurons: A Dual-Probe Microdialysis Study in the Ventral Tegmental Area and Prefrontal Cortex of the Rat Brain
J Pharmacol Exp Ther 1998 285: 143-154. [Abstract] [Full Text] [PDF]  

Manami Kimura, Kohei Sawada, Takehiko Miyagawa, Manabu Kuwada, Kouichi Katayama, and Yukio Nishizawa

Role of Glutamate Receptors and Voltage-Dependent Calcium and Sodium Channels in the Extracellular Glutamate/Aspartate Accumulation and Subsequent Neuronal Injury Induced by Oxygen/Glucose Deprivation in Cultured Hippocampal Neurons
J Pharmacol Exp Ther 1998 285: 178-185. [Abstract] [Full Text] [PDF]  

Jeanne M. Fahey, Gary A. Pritchard, Lisa L. von Moltke, John S. Pratt, Jeffrey M. Grassi, Richard I. Shader, and David J. Greenblatt

Effects of Ketoconazole on Triazolam Pharmacokinetics, Pharmacodynamics and Benzodiazepine Receptor Binding in Mice
J Pharmacol Exp Ther 1998 285: 271-276. [Abstract] [Full Text] [PDF]  

Paul M. Kunko, Dawn French, and Sari Izenwasser

Alterations in Locomotor Activity during Chronic Cocaine Administration: Effect on Dopamine Receptors and Interaction with Opioids
J Pharmacol Exp Ther 1998 285: 277-284. [Abstract] [Full Text] [PDF]  

David G. Watson, Jeannette M. Watterson, and Robert H. Lenox

Sodium Valproate Down-regulates the Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) in Immortalized Hippocampal Cells: A Property of Protein Kinase C-Mediated Mood Stabilizers
J Pharmacol Exp Ther 1998 285: 307-316. [Abstract] [Full Text] [PDF]  

A. Chistina Grobin and Ariel Y. Deutch

Dopaminergic Regulation of Extracellular -Aminobutyric Acid Levels in the Prefrontal Cortex of the Rat
J Pharmacol Exp Ther 1998 285: 350-357. [Abstract] [Full Text] [PDF]  

Maryellen Fazen Eckenhoff and Roderic G. Eckenhoff

Quantitative Autoradiography of Halothane Binding in Rat Brain
J Pharmacol Exp Ther 1998 285: 371-376. [Abstract] [Full Text] [PDF]  

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS:

Joseph A. Hankin, Carl E. Clay, and Robert C. Murphy

The Effects of Ethanol and Acetaldehyde on the Metabolism of Prostaglandin E₂ and Leukotriene B₄ in Isolated Rat Hepatocytes
J Pharmacol Exp Ther 1998 285: 155-161. [Abstract] [Full Text] [PDF]  

Karsten Gronert, Sean P. Colgan, and Charles N. Serhan

Characterization of Human Neutrophil and Endothelial Cell Ligand-Operated Extracellular Acidification Rate by Microphysiometry: Impact of Reoxygenation
J Pharmacol Exp Ther 1998 285: 252-261. [Abstract] [Full Text] [PDF]  

RENAL PHARMACOLOGY:

Stephen H. Wright, Theresa M. Wunz, J. North, and James L. Stevens

Na-Dependent Transport of S-(1,2-Dichlorovinyl)-L-Cysteine by Renal Brush-Border Membrane Vesicles
J Pharmacol Exp Ther 1998 285: 162-169. [Abstract] [Full Text] [PDF]  

Toshiko Tanaka-Kagawa, Mieko Suzuki, Akira Naganuma, Nobuaki Yamanaka, and Nobumasa Imura

Strain Difference in Sensitivity of Mice to Renal Toxicity of Inorganic Mercury
J Pharmacol Exp Ther 1998 285: 335-341. [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

P. G. Gunasekar, J. L. Borowitz, and G. E. Isom

Cyanide-Induced Generation of Oxidative Species: Involvement of Nitric Oxide Synthase and Cyclooxygenase-2
J Pharmacol Exp Ther 1998 285: 236-241. [Abstract] [Full Text] [PDF]  

Raviprakash R. Dugyala, Raghubir P. Sharma, Masashi Tsunoda, and Ronald T. Riley

Tumor Necrosis Factor- as a Contributor in Fumonisin B₁ Toxicity
J Pharmacol Exp Ther 1998 285: 317-324. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.