ANALGESIA AND DRUGS OF ABUSE:

Cuiping Chen and Gary M. Pollack

Blood-Brain Disposition and Antinociceptive Effects of [D-Penicillamine^2,5]enkephalin in the Mouse
J Pharmacol Exp Ther 1997 283: 1151-1159. [Abstract] [Full Text] [PDF]  

Sanjay N. Thorat and Donna L. Hammond

Modulation of Nociception by Microinjection of Delta-1 and Delta-2 Opioid Receptor Ligands in the Ventromedial Medulla of the Rat
J Pharmacol Exp Ther 1997 283: 1185-1192. [Abstract] [Full Text] [PDF]  

Benjamin Kest, Gabrielle McLemore, Bernard Kao, and Charles E. Inturrisi

The Competitive -Amino-3-Hydroxy-5-Methylisoxazole-4-Propionate Receptor Antagonist LY293558 Attenuates and Reverses Analgesic Tolerance to Morphine But Not to Delta or Kappa Opioids
J Pharmacol Exp Ther 1997 283: 1249-1255. [Abstract] [Full Text] [PDF]  

Philip G. Szekeres and John R. Traynor

Delta Opioid Modulation of the Binding of Guanosine-5-O-(3-[³⁵S]thio)triphosphate to NG108-15 Cell Membranes: Characterization of Agonist and Inverse Agonist Effects
J Pharmacol Exp Ther 1997 283: 1276-1284. [Abstract] [Full Text] [PDF]  

Robert M. Caudle, Andrew J. Mannes, and Michael J. Iadarola

GR89,696 Is a Kappa-2 Opioid Receptor Agonist and a Kappa-1 Opioid Receptor Antagonist in the Guinea Pig Hippocampus
J Pharmacol Exp Ther 1997 283: 1342-1349. [Abstract] [Full Text] [PDF]  

L. B. Hough, J. W. Nalwalk, B. Y. Li, R. Leurs, W.M.P.B. Menge, H. Timmerman, M. E. Carlile, C. Cioffi, and M. Wentland

Novel Qualitative Structure-Activity Relationships for the Antinociceptive Actions of H₂ Antagonists, H₃ Antagonists and Derivatives
J Pharmacol Exp Ther 1997 283: 1534-1543. [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

Kristina Reid, Tian-Zhi Guo, M. Frances Davies, and Mervyn Maze

Nifedipine, an L-type Calcium Channel Blocker, Restores the Hypnotic Response in Rats Made Tolerant to the Alpha-2 Adrenergic Agonist Dexmedetomidine
J Pharmacol Exp Ther 1997 283: 993-999. [Abstract] [Full Text] [PDF]  

Mitchell J. Picker

Discriminative Stimulus Effects of the Mixed-Opioid Agonist/Antagonist Dezocine: Cross-Substitution by Mu and Delta Opioid Agonists
J Pharmacol Exp Ther 1997 283: 1009-1017. [Abstract] [Full Text] [PDF]  

Chyan E. Lau and Anne C. Heatherington

Pharmacokinetic-Pharmacodynamic Modeling of Stimulatory and Sedative Effects of Alprazolam: Timing Performance Deficits
J Pharmacol Exp Ther 1997 283: 1119-1129. [Abstract] [Full Text] [PDF]  

David R. Compton and Billy R. Martin

The Effect of the Enzyme Inhibitor Phenylmethylsulfonyl Fluoride on the Pharmacological Effect of Anandamide in the Mouse Model of Cannabimimetic Activity
J Pharmacol Exp Ther 1997 283: 1138-1143. [Abstract] [Full Text] [PDF]  

Pat Bauco and Roy A. Wise

Synergistic Effects of Cocaine with Lateral Hypothalamic Brain Stimulation Reward: Lack of Tolerance or Sensitization
J Pharmacol Exp Ther 1997 283: 1160-1167. [Abstract] [Full Text] [PDF]  

Linda J. Bristow, Neil Collinson, Gina P. Cook, Neil Curtis, Stephen B. Freedman, Janusz J. Kulagowski, Paul D. Leeson, Smita Patel, C. Ian Ragan, Mark Ridgill, Kay L. Saywell, and Mark D. Tricklebank

L-745,870, a Subtype Selective Dopamine D₄ Receptor Antagonist, Does Not Exhibit a Neuroleptic-Like Profile in Rodent Behavioral Tests
J Pharmacol Exp Ther 1997 283: 1256-1263. [Abstract] [Full Text] [PDF]  

C. Sánchez, J. Arnt, B. Costall, M.E. Kelly, E. Meier, R.J. Naylor, and J. Perregaard

The Selective ₂-Ligand Lu 28-179 Has Potent Anxiolytic-Like Effects in Rodents
J Pharmacol Exp Ther 1997 283: 1323-1332. [Abstract] [Full Text] [PDF]  

H. H. Hansen, C. Sánchez, and E. Meier

Neonatal Administration of the Selective Serotonin Reuptake Inhibitor Lu 10-134-C Increases Forced Swimming-Induced Immobility in Adult Rats: A Putative Animal Model of Depression?
J Pharmacol Exp Ther 1997 283: 1333-1341. [Abstract] [Full Text] [PDF]  

Sven Ahlenius, Evalena Ericson, Viveka Hillegaart, Lars B. Nilsson, Peter Salmi, and Agneta Wijkström

In Vivo Effects of Remoxipride and Aromatic Ring Metabolites in the Rat
J Pharmacol Exp Ther 1997 283: 1356-1366. [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR PHARMACOLOGY:

Reid Hayward, Tareck O. Nossuli, and Allan M. Lefer

Heparinase III Exerts Endothelial and Cardioprotective Effects in Feline Myocardial Ischemia-Reperfusion Injury
J Pharmacol Exp Ther 1997 283: 1032-1038. [Abstract] [Full Text] [PDF]  

Cornelis J.J.G. Bol, Meindert Danhof, Donald R. Stanski, and Jaap W. Mandema

Pharmacokinetic-Pharmacodynamic Characterization of the Cardiovascular, Hypnotic, EEG and Ventilatory Responses to Dexmedetomidine in the Rat
J Pharmacol Exp Ther 1997 283: 1051-1058. [Abstract] [Full Text] [PDF]  

Francis G. Spinale, Henry H. Holzgrefe, Rupak Mukherjee, Maria L. Webb, R. Barry Hird, Martyn J. Cavallo, James R. Powell, and William H. Koster

Angiotensin-Converting Enzyme Inhibition and Angiotensin II Subtype-1 Receptor Blockade during the Progression of Left Ventricular Dysfunction: Differential Effects on Myocyte Contractile Processes
J Pharmacol Exp Ther 1997 283: 1082-1094. [Abstract] [Full Text] [PDF]  

Sébastien Roux, Volker Breu, Thomas Giller, Werner Neidhart, Henri Ramuz, Philippe Coassolo, Jean Paul Clozel, and Martine Clozel

Ro 61-1790, a New Hydrosoluble Endothelin Antagonist: General Pharmacology and Effects on Experimental Cerebral Vasospasm
J Pharmacol Exp Ther 1997 283: 1110-1118. [Abstract] [Full Text] [PDF]  

Sajida A. Khan, Nicole R. Higdon, Jackson B. Hester, and Kaushik D. Meisheri

Pharmacological Characterization of Novel Cyanoguanidines as Vascular K_ATP Channel Blockers
J Pharmacol Exp Ther 1997 283: 1207-1213. [Abstract] [Full Text] [PDF]  

Shizuo Yamada, Takashi Ohkura, Tooru Yamadera, Osamu Ito, Ryohei Kimura, Yoshihisa Nozawa, Shuji Hayashi, and Hidekazu Miyake

Abnormality in Plasma Catecholamines and Myocardial Adrenoceptors in Cardiomyopathic BIO 53.58 Syrian Hamsters and Improvement by Metoprolol Treatment
J Pharmacol Exp Ther 1997 283: 1389-1395. [Abstract] [Full Text] [PDF]  

Lynn P. Weber and Kathleen M. Macleod

Influence of Streptozotocin Diabetes on the Alpha-1 Adrenoceptor and Associated G Proteins in Rat Arteries
J Pharmacol Exp Ther 1997 283: 1469-1478. [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR PHARMACOLOGY:

William R. Kem, Vladimir M. Mahnir, Roger L. Papke, and Christopher J. Lingle

Anabaseine Is a Potent Agonist on Muscle and Neuronal Alpha-Bungarotoxin-Sensitive Nicotinic Receptors
J Pharmacol Exp Ther 1997 283: 979-992. [Abstract] [Full Text] [PDF]  

J. M. Loudon, S. M. Bromidge, F. Brown, M. S. G. Clark, J. P. Hatcher, J. Hawkins, G. J. Riley, G. Noy, and B. S. Orlek

SB 202026: A Novel Muscarinic Partial Agonist with Functional Selectivity for M₁ Receptors
J Pharmacol Exp Ther 1997 283: 1059-1068. [Abstract] [Full Text] [PDF]  

Jeffrey H. Sheldon, N. Wesley Norton, and Thomas M. Argentieri

Inhibition of Guinea Pig Detrusor Contraction by NS-1619 Is Associated with Activation of BK_Ca and Inhibition of Calcium Currents
J Pharmacol Exp Ther 1997 283: 1193-1200. [Abstract] [Full Text] [PDF]  

Jerzy Barankiewicz, Anne M. Danks, Elie Abushanab, Lewis Makings, Torsten Wiemann, Roi Ann Wallis, Palle V. P. Pragnacharyulu, Anthony Fox, and Paul J. Marangos

Regulation of Adenosine Concentration and Cytoprotective Effects of Novel Reversible Adenosine Deaminase Inhibitors
J Pharmacol Exp Ther 1997 283: 1230-1238. [Abstract] [Full Text] [PDF]  

G. Fischer, V. Mutel, G. Trube, P. Malherbe, J. N. C. Kew, E. Mohacsi, M. P. Heitz, and J. A. Kemp

Ro 25-6981, a Highly Potent and Selective Blocker of N-Methyl-D-aspartate Receptors Containing the NR2B Subunit. Characterization in Vitro
J Pharmacol Exp Ther 1997 283: 1285-1292. [Abstract] [Full Text] [PDF]  

Manickavasagom Alkondon, Edna F. R. Pereira, Catão T. F. Barbosa, and Edson X. Albuquerque

Neuronal Nicotinic Acetylcholine Receptor Activation Modulates -Aminobutyric Acid Release from CA1 Neurons of Rat Hippocampal Slices
J Pharmacol Exp Ther 1997 283: 1396-1411. [Abstract] [Full Text] [PDF]  

Robert L. Panek, Gina H. Lu, Sylvester R. Klutchko, Brian L. Batley, Tawny K. Dahring, James M. Hamby, Hussein Hallak, Annette M. Doherty, and Joan A. Keiser

In Vitro Pharmacological Characterization of PD 166285, a New Nanomolar Potent and Broadly Active Protein Tyrosine Kinase Inhibitor
J Pharmacol Exp Ther 1997 283: 1433-1444. [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY/GENE THERAPY:

Shigehiro Ohdo, Tomoko Makinosumi, Takashi Ishizaki, Eiji Yukawa, Shun Higuchi, Shigeyuki Nakano, and Nobuya Ogawa

Cell Cycle-Dependent Chronotoxicity of Irinotecan Hydrochloride in Mice
J Pharmacol Exp Ther 1997 283: 1383-1388. [Abstract] [Full Text] [PDF]  

Darin Hurnanen, Hing Man Chan, and Stan Kubow

The Protective Effect of Metallothionein Against Lipid Peroxidation Caused by Retinoic Acid in Human Breast Cancer Cells
J Pharmacol Exp Ther 1997 283: 1520-1528. [Abstract] [Full Text] [PDF]  

DEVELOPMENTAL PHARMACOLOGY:

D. G. McCarver, H. R. Thomasson, S. S. Martier, R. J. Sokol, and T.-K. Li

Alcohol Dehydrogenase-2*3 Allele Protects Against Alcohol-Related Birth Defects Among African Americans
J Pharmacol Exp Ther 1997 283: 1095-1101. [Abstract] [Full Text] [PDF]  

DRUG METABOLISM AND DISPOSITION:

Atsuyuki Kakee, Tetsuya Terasaki, and Yuichi Sugiyama

Selective Brain to Blood Efflux Transport of para-Aminohippuric Acid across the Blood-Brain Barrier: In Vivo Evidence by Use of the Brain Efflux Index Method
J Pharmacol Exp Ther 1997 283: 1018-1025. [Abstract] [Full Text] [PDF]  

Xue-Jun Zhao and Takashi Ishizaki

The In Vitro Hepatic Metabolism of Quinine in Mice, Rats and Dogs: Comparison with Human Liver Microsomes
J Pharmacol Exp Ther 1997 283: 1168-1176. [Abstract] [Full Text] [PDF]  

David J. Fraser, René Feyereisen, Greg R. Harlow, and James R. Halpert

Isolation, Heterologous Expression and Functional Characterization of a Novel Cytochrome P450 3A Enzyme from a Canine Liver cDNA Library
J Pharmacol Exp Ther 1997 283: 1425-1432. [Abstract] [Full Text] [PDF]  

Yukiko Minamiyama, Shigekazu Takemura, Susumu Imaoka, Yoshihiko Funae, Yuko Tanimoto, and Masayasu Inoue

Irreversible Inhibition of Cytochrome P450 by Nitric Oxide
J Pharmacol Exp Ther 1997 283: 1479-1485. [Abstract] [Full Text] [PDF]  

Gen-Fu Chen, Martin J. J. Ronis, Paul E. Thomas, David J. Flint, and Thomas M. Badger

Hormonal Regulation of Microsomal Cytochrome P450 2C11 in Rat Liver and Kidney
J Pharmacol Exp Ther 1997 283: 1486-1494. [Abstract] [Full Text] [PDF]  

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher, Danny D. Shen, Kent L. Kunze, Christopher L. Marsh, James D. Perkins, and Kenneth E. Thummel

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism
J Pharmacol Exp Ther 1997 283: 1552-1562. [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL PHARMACOLOGY:

Yukiko Mine, Takashi Yoshikawa, Seiko Oku, Ryuji Nagai, Naoyuki Yoshida, and Kanoo Hosoki

Comparison of Effect of Mosapride Citrate and Existing 5-HT₄ Receptor Agonists on Gastrointestinal Motility In Vivo and In Vitro
J Pharmacol Exp Ther 1997 283: 1000-1008. [Abstract] [Full Text] [PDF]  

Corrado Blandizzi, Rocchina Colucci, Diego Carignani, Gloria Lazzeri, and Mario Del Tacca

Positive Modulation of Pepsinogen Secretion by Gastric Acidity After Vagal Cholinergic Stimulation
J Pharmacol Exp Ther 1997 283: 1043-1050. [Abstract] [Full Text] [PDF]  

U. D. Sohn, K. M. Harnett, W. Cao, H. Rich, N. Kim, J. Behar, and P. Biancani

Acute Experimental Esophagitis Activates a Second Signal Transduction Pathway in Cat Smooth Muscle from the Lower Esophageal Sphincter
J Pharmacol Exp Ther 1997 283: 1293-1304. [Abstract] [Full Text] [PDF]  

Lu Liu and Ian M. Coupar

Involvement of Alpha-2 Adrenoceptors in the Effects of Moxonidine on Intestinal Motility and Fluid Transport
J Pharmacol Exp Ther 1997 283: 1367-1374. [Abstract] [Full Text] [PDF]  

Takako Yoshino and Isamu Yamaguchi

Possible Involvement of 5-HT₂ Receptor Activation in Aggravation of Diet-Induced Acute Pancreatitis in Mice
J Pharmacol Exp Ther 1997 283: 1495-1502. [Abstract] [Full Text] [PDF]  

IMMUNOPHARMACOLOGY:

Yoko Hieda, Dan E. Keyler, John T. Vandevoort, Justin K. Kane, Cathy A. Ross, Donna E. Raphael, R. Sam Niedbalas, and Paul R. Pentel

Active Immunization Alters the Plasma Nicotine Concentration in Rats
J Pharmacol Exp Ther 1997 283: 1076-1081. [Abstract] [Full Text] [PDF]  

Karl W. Mollison, Thomas A. Fey, Ruth A. Krause, Janet M. Andrews, Pat T. Bretheim, Julie A. Brandt, Megumi Kawai, Rolf Wagner, Gin C. Hsieh, and Jay R. Luly

Discovery of Less Nephrotoxic FK506 Analogs and Determining Immunophilin Dependence of Immunosuppressant Nephrotoxicity with a Novel Single-Dose Rat Cisplatin Potentiation Assay
J Pharmacol Exp Ther 1997 283: 1509-1519. [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Christopher W. Stewart, John F. Bowyer, and William Slikker Jr.

Elevated Environmental Temperatures Can Induce Hyperthermia During d-Fenfluramine Exposure and Enhance 5-Hydroxytryptamine (5-HT) Depletion in the Brain
J Pharmacol Exp Ther 1997 283: 1144-1150. [Abstract] [Full Text] [PDF]  

C. Thetford Smothers, James J. Mrotek, and David M. Lovinger

Chronic Ethanol Exposure Leads to a Selective Enhancement of N-Methyl-D-aspartate Receptor Function in Cultured Hippocampal Neurons
J Pharmacol Exp Ther 1997 283: 1214-1222. [Abstract] [Full Text] [PDF]  

Ilse Smolders, Ghous M. Khan, Hilde Lindekens, Steven Prikken, Craig A. Marvin, Jacqueline Manil, Guy Ebinger, and Yvette Michotte

Effectiveness of Vigabatrin against Focally Evoked Pilocarpine-Induced Seizures and Concomitant Changes in Extracellular Hippocampal and Cerebellar Glutamate, -Aminobutyric Acid and Dopamine Levels, a Microdialysis-Electrocorticography Study in Freely Moving Rats
J Pharmacol Exp Ther 1997 283: 1239-1248. [Abstract] [Full Text] [PDF]  

Chris G. Parsons, Wojciech Danysz, Günter Quack, Sabine Hartmann, Bianke Lorenz, Christine Wollenburg, Leokadia Baran, Edmund Przegalinski, Wojciech Kostowski, Pawel Krzascik, Boris Chizh, and P. Max. Headley

Novel Systemically Active Antagonists of the Glycine Site of the N-Methyl-D-aspartate Receptor: Electrophysiological, Biochemical and Behavioral Characterization
J Pharmacol Exp Ther 1997 283: 1264-1275. [Abstract] [Full Text] [PDF]  

Michael J. Owens, W. Neal Morgan, Susan J. Plott, and Charles B. Nemeroff

Neurotransmitter Receptor and Transporter Binding Profile of Antidepressants and Their Metabolites
J Pharmacol Exp Ther 1997 283: 1305-1322. [Abstract] [Full Text] [PDF]  

Melanie P. Gygi, Annette E. Fleckenstein, James W. Gibb, and Glen R. Hanson

Role of Endogenous Dopamine in the Neurochemical Deficits Induced by Methcathinone
J Pharmacol Exp Ther 1997 283: 1350-1355. [Abstract] [Full Text] [PDF]  

Edward F. Cregan, James Peeling, Dale Corbett, Alastair M. Buchan, John Saunders, Roland N. Auer, M. Gao, Dennis J. Mccarthy, Mark S. Eisman, T. Mark Campbell, Robert J. Murray, Mary L. Stagnitto, and Gene C. Palmer

[(S)-Alpha-Phenyl-2-Pyridine-Ethanamine Dihydrochloride], A Low Affinity Uncompetitive N-Methyl-D-Aspartic Acid Antagonist, Is Effective in Rodent Models of Global and Focal Ischemia
J Pharmacol Exp Ther 1997 283: 1412-1424. [Abstract] [Full Text] [PDF]  

Shin-Ichi Iwata, G. H. Keikilani Hewlett, Sandra T. Ferrell, Lana Kantor, and Margaret E. Gnegy

Enhanced Dopamine Release and Phosphorylation of Synapsin I and Neuromodulin in Striatal Synaptosomes after Repeated Amphetamine
J Pharmacol Exp Ther 1997 283: 1445-1452. [Abstract] [Full Text] [PDF]  

S. Bovetto, P.-A. Boyer, P. Skolnick, and L. H. Fossom

Chronic Administration of a Glycine Partial Agonist Alters the Expression of N-Methyl-D-aspartate Receptor Subunit mRNAs
J Pharmacol Exp Ther 1997 283: 1503-1508. [Abstract] [Full Text] [PDF]  

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS:

Yan Zhang, Alex Shaffer, Joseph Portanova, Karen Seibert, and Peter C. Isakson

Inhibition of Cyclooxygenase-2 Rapidly Reverses Inflammatory Hyperalgesia and Prostaglandin E₂ Production
J Pharmacol Exp Ther 1997 283: 1069-1075. [Abstract] [Full Text] [PDF]  

PULMONARY PHARMACOLOGY:

Shigeji Matsumoto, Mamoru Takeda, Chikako Saiki, Toshiaki Takahashi, and Kohei Ojima

Effects of Tachykinins on Rapidly Adapting Pulmonary Stretch Receptors and Total Lung Resistance in Anesthetized, Artificially Ventilated Rabbits
J Pharmacol Exp Ther 1997 283: 1026-1031. [Abstract] [Full Text] [PDF]  

Susan M. Cibulsky and David C. Thompson

Absence of Tachykinin Involvement in Leukotriene D₄ and Antigen-Induced Contraction of Guinea Pig Isolated Bronchus
J Pharmacol Exp Ther 1997 283: 1102-1109. [Abstract] [Full Text] [PDF]  

David C. Underwood, Steve Bochnowicz, Ruth R. Osborn, Mark A. Luttmann, and Douglas W. P. Hay

Nonpeptide Endothelin Receptor Antagonists. X. Inhibition of Endothelin-1- and Hypoxia-Induced Pulmonary Pressor Responses in the Guinea Pig by the Endothelin Receptor Antagonist, SB 217242
J Pharmacol Exp Ther 1997 283: 1130-1137. [Abstract] [Full Text] [PDF]  

Dianne D. Rees, Joseph D. Brain, Mary Ellen Wohl, John L. Humes, and Richard A. Mumford

Inhibition of Neutrophil Elastase in CF Sputum by L-658,758
J Pharmacol Exp Ther 1997 283: 1201-1206. [Abstract] [Full Text] [PDF]  

Stefan Uhlig, Roland Lewis Featherstone, Heinz-Dieter Held, Rolf Nüsing, Christian Schudt, and Albrecht Wendel

Attenuation by Phosphodiesterase Inhibitors of Lipopolysaccharide-Induced Thromboxane Release and Bronchoconstriction in Rat Lungs
J Pharmacol Exp Ther 1997 283: 1453-1459. [Abstract] [Full Text] [PDF]  

RENAL PHARMACOLOGY:

Satohiro Masuda, Hideyuki Saito, and Ken-Ichi Inui

Interactions of Nonsteroidal Anti-inflammatory Drugs with Rat Renal Organic Anion Transporter, OAT-K1
J Pharmacol Exp Ther 1997 283: 1039-1042. [Abstract] [Full Text] [PDF]  

K. J. Ullrich, G. Rumrich, T. R. Burke, S. P. Shirazi-Beechey, and H.-J. Lang

Interaction of Alkyl/Arylphosphonates, Phosphonocarboxylates and Diphosphonates with Different Anion Transport Systems in the Proximal Renal Tubule
J Pharmacol Exp Ther 1997 283: 1223-1229. [Abstract] [Full Text] [PDF]  

Herbert Schramek, Doris Wilflingseder, Verena Pollack, Ruth Freudinger, Sigrid Mildenberger, and Michael Gekle

Ochratoxin A-Induced Stimulation of Extracellular Signal-Regulated Kinases 1/2 is Associated with Madin-Darby Canine Kidney-C7 Cell Dedifferentiation
J Pharmacol Exp Ther 1997 283: 1460-1468. [Abstract] [Full Text] [PDF]  

Masahiko Satoh, Noriko Nishimura, Yoshitaka Kanayama, Akira Naganuma, Tsuguyoshi Suzuki, and Chiharu Tohyama

Enhanced Renal Toxicity by Inorganic Mercury in Metallothionein-Null Mice
J Pharmacol Exp Ther 1997 283: 1529-1533. [Abstract] [Full Text] [PDF]  

TOXICOLOGY:

Shayla L. Waters, Satinder S. Sarang, Kevin K. W. Wang, and Rick G. Schnellmann

Calpains Mediate Calcium and Chloride Influx During the Late Phase of Cell Injury
J Pharmacol Exp Ther 1997 283: 1177-1184. [Abstract] [Full Text] [PDF]  

Dominic P. Williams, Munir Pirmohamed, Dean J. Naisbitt, James L. Maggs, and B. Kevin Park

Neutrophil Cytotoxicity of the Chemically Reactive Metabolite(s) of Clozapine: Possible Role in Agranulocytosis
J Pharmacol Exp Ther 1997 283: 1375-1382. [Abstract] [Full Text] [PDF]  

Ramaswamy A. Iyer, Raymond B. Baggs, and M. W. Anders

Nephrotoxicity of the Glutathione and Cysteine S-Conjugates of the Sevoflurane Degradation Product 2-(Fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (Compound A) in Male Fischer 344 Rats
J Pharmacol Exp Ther 1997 283: 1544-1551. [Abstract] [Full Text] [PDF]  

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