ARTICLES:

MA Hill, MJ Davis, J Song, and H Zou

Calcium dependence of indolactam-mediated contractions in resistance vessels
J Pharmacol Exp Ther 1996 276: 867-874. [Abstract] [PDF]  

NY Fan, CA Powers, and CT Jr Stier

Lack of antidiuretic activity of lanreotide in the diabetes insipidus rat
J Pharmacol Exp Ther 1996 276: 875-881. [Abstract] [PDF]  

RJ Primus, J Yu, J Xu, C Hartnett, M Meyyappan, C Kostas, TV Ramabhadran, and DW Gallager

Allosteric uncoupling after chronic benzodiazepine exposure of recombinant gamma-aminobutyric acid(A) receptors expressed in Sf9 cells: ligand efficacy and subtype selectivity
J Pharmacol Exp Ther 1996 276: 882-890. [Abstract] [PDF]  

X Bossuyt, M Muller, B Hagenbuch, and PJ Meier

Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver
J Pharmacol Exp Ther 1996 276: 891-896. [Abstract] [PDF]  

KJ Rhoden, G Tallini, and JS Douglas

H+-K+ ATPase inhibitors cause relaxation of guinea pig and human airway smooth muscle in vitro
J Pharmacol Exp Ther 1996 276: 897-903. [Abstract] [PDF]  

EP Prinssen, MS Kleven, J Vignon, JM Kamenka, and W Koek

Effects of repeated administration of N-[1-(2-benzo(b)- thiophenyl)cyclohexy]piperidine and cocaine on locomotor activity in C57BL/6 mice
J Pharmacol Exp Ther 1996 276: 904-911. [Abstract] [PDF]  

JF Tjia, J Colbert, and DJ Back

Theophylline metabolism in human liver microsomes: inhibition studies
J Pharmacol Exp Ther 1996 276: 912-917. [Abstract] [PDF]  

SD Yoo, JW Holladay, TK Fincher, H Baumann, and MJ Dewey

Altered disposition and antidepressant activity of imipramine in transgenic mice with elevated alpha-1-acid glycoprotein
J Pharmacol Exp Ther 1996 276: 918-922. [Abstract] [PDF]  

S Ouwerkerk-Mahadevan, JH van Boom, and GJ Mulder

Isoenzyme-selective inhibition of glutathione conjugation in vivo: selective inhibition of the conjugation of S-2-Bromoisovalerylurea in the rat
J Pharmacol Exp Ther 1996 276: 923-928. [Abstract] [PDF]  

Q Chen, PD Banick, and SR Thom

Functional inhibition of rat polymorphonuclear leukocyte B2 integrins by hyperbaric oxygen is associated with impaired cGMP synthesis
J Pharmacol Exp Ther 1996 276: 929-933. [Abstract] [PDF]  

H Kan, Y Ruan, and U Malik K

Localization and characterization of the subtypes(s) of muscarinic receptor involved in prostacyclin synthesis in rabbit heart
J Pharmacol Exp Ther 1996 276: 934-941. [Abstract] [PDF]  

J Bergman, RD Spealman, BK Madras, and S Rosenzweig-Lipson

Agonist efficacy and the behavioral effects of dopamine D1 receptor ligands: drug interaction studies in squirrel monkeys
J Pharmacol Exp Ther 1996 276: 942-950. [Abstract] [PDF]  

GZ Sudo and MC Sanguinetti

Intracellular [Mg++] determines specificity of K+ channel block by a class III antiarrhythmic drug
J Pharmacol Exp Ther 1996 276: 951-957. [Abstract] [PDF]  

Q Lin, YB Peng, and WD Willis

Antinociception and inhibition from the periaqueductal gray are mediated in part by spinal 5-hydroxytryptamine(1A) receptors
J Pharmacol Exp Ther 1996 276: 958-967. [Abstract] [PDF]  

M Leist, S Auer-Barth, and A Wendel

Tumor necrosis factor production in the perfused mouse liver and its pharmacological modulation by methylxanthines
J Pharmacol Exp Ther 1996 276: 968-976. [Abstract] [PDF]  

L Schmid, M Bottlaender, E Brouillet, C Fuseau, and M Maziere

Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon
J Pharmacol Exp Ther 1996 276: 977-983. [Abstract] [PDF]  

NA Payne and JG Gerber

The effect of beta andrenoceptor stimulation of canine stomach on pentagastrin-stimulated histamine release
J Pharmacol Exp Ther 1996 276: 984-988. [Abstract] [PDF]  

S Matsuyama, H Sakiyama, K Nei, and C Tanaka

Identification of putative 5-hydroxytryptamine(4) (5-HT4) receptors in guinea pig stomach: The effect of TKS159, a novel agonist, on gastric motility and acetylcholine release
J Pharmacol Exp Ther 1996 276: 989-995. [Abstract] [PDF]  

K Morita, K Teraoka, M Oka, and M Levine

Inhibitory action of palytoxin on ascorbic acid transport into cultured bovine adrenal chromaffin cells
J Pharmacol Exp Ther 1996 276: 996-1001. [Abstract] [PDF]  

J Peris

Repeated cocaine injections decrease the function of striatal gamma- aminobutyric acid(A) receptors
J Pharmacol Exp Ther 1996 276: 1002-1008. [Abstract] [PDF]  

R Leurs, M Kathmann, RC Vollinga, WM Menge, E Schlicker, and H Timmerman

Histamine homologues discriminating between two functional H3 receptor assays. Evidence for H3 receptor heterogeneity?
J Pharmacol Exp Ther 1996 276: 1009-1015. [Abstract] [PDF]  

GJ Wang, J Shan, PK Pang, MC Yang, CJ Chou, and CF Chen

The vasorelaxing action of rutaecarpine: direct paradoxical effects on intracellular calcium concentration of vascular smooth muscle and endothelial cells
J Pharmacol Exp Ther 1996 276: 1016-1021. [Abstract] [PDF]  

CW Lin, BR Bianchi, TR Miller, MA Stashko, SS Wang, P Curzon, L Bednarz, KE Asin, and DR Britton

Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636
J Pharmacol Exp Ther 1996 276: 1022-1029. [Abstract] [PDF]  

JM Herbert, A Bernat, F Dol, JP Herault, B Crepon, and JC Lormeau

DX 9065A a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies
J Pharmacol Exp Ther 1996 276: 1030-1038. [Abstract] [PDF]  

S Sagan, G Chassaing, L Pradier, and S Lavielle

Tachykinin peptides affect differently the second messenger pathways after binding to CHO-expressed human NK-1 receptors
J Pharmacol Exp Ther 1996 276: 1039-1048. [Abstract] [PDF]  

TJ Abbruscato, SA Williams, A Misicka, AW Lipkowski, VJ Hruby, and TP Davis

Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives
J Pharmacol Exp Ther 1996 276: 1049-1057. [Abstract] [PDF]  

JE Dildy-Mayfield, EI 2nd Eger, and RA Harris

Anesthetics produce subunit-selective actions on glutamate receptors
J Pharmacol Exp Ther 1996 276: 1058-1065. [Abstract] [PDF]  

MP Gygi, JW Gibb, and GR Hanson

Methcathinone: an initial study of its effects on monoaminergic systems
J Pharmacol Exp Ther 1996 276: 1066-1072. [Abstract] [PDF]  

N Chiu, I Park, and IA Reid

Stimulation of renin secretion by the phosphodiesterase IV inhibitor rolipram
J Pharmacol Exp Ther 1996 276: 1073-1077. [Abstract] [PDF]  

FJ Dumont, H Ok, S Lin, CA Kastner, J Cryan, MM Martin, G Wiederrecht, and MJ Staruch

Mixed agonist/antagonist activity of an FK-506-related immunosuppressant: biological and biochemical characterization
J Pharmacol Exp Ther 1996 276: 1078-1088. [Abstract] [PDF]  

G Liapakis, C Hoeger, J Rivier, and T Reisine

Development of a selective agonist at the somatostatin receptor subtype sstr1
J Pharmacol Exp Ther 1996 276: 1089-1094. [Abstract] [PDF]  

DA Cox and ML Cohen

Selective enhancement of 5-hydroxytryptamine-induced contraction of porcine coronary artery by oxidized low-density lipoprotein
J Pharmacol Exp Ther 1996 276: 1095-1103. [Abstract] [PDF]  

RA Hahn, BR MacDonald, M Chastain, BW Grinnell, and PJ Simpson

Evaluation of activated protein C on canine infarct size in a nonthrombotic model of myocardial reperfusion injury
J Pharmacol Exp Ther 1996 276: 1104-1110. [Abstract] [PDF]  

PJ Winsauer, MA Bixler, and PC Mele

Comparison of the effects of typical and atypical anxiolytics on learning in monkeys and rats
J Pharmacol Exp Ther 1996 276: 1111-1127. [Abstract] [PDF]  

MI Rosen, TJ McMahon, FA Hameedi, HR Pearsall, SW Woods, MJ Kreek, and TR Kosten

Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal
J Pharmacol Exp Ther 1996 276: 1128-1135. [Abstract] [PDF]  

M Ocana, M Barrios, and JM Baeyens

Cromakalim differentially enhances antinociception induced by agonists of alpha(2)adrenoceptors, gamma-aminobutyric acid(B), mu and kappa opioid receptors
J Pharmacol Exp Ther 1996 276: 1136-1142. [Abstract] [PDF]  

T Ohtomo, H Saito, N Inotsume, M Yasuhara, and KI Inui

Transport of levofloxacin in a kidney epithelial cell line, LLC-PK1: interaction with organic cation transporters in apical and basolateral membranes
J Pharmacol Exp Ther 1996 276: 1143-1148. [Abstract] [PDF]  

MP Davies, LC Freeman, and RS Kass

Dual actions of the novel class III antiarrhythmic drug NE-10064 on delayed potassium channel currents in guinea pig ventricular and sinoatrial node cells
J Pharmacol Exp Ther 1996 276: 1149-1154. [Abstract] [PDF]  

XF Deng, S Chemtob, G Almazan, and DR Varma

Ontogenic differences in the functions of myocardial alpha1 adrenoceptor subtypes in rats
J Pharmacol Exp Ther 1996 276: 1155-1161. [Abstract] [PDF]  

O Porat, D Neumann, O Zamir, S Nachshon, E Feigin, J Cohen, and N Zamir

Erythropoietin stimulates atrial natriuretic peptide secretion from adult rat cardiac atrium
J Pharmacol Exp Ther 1996 276: 1162-1168. [Abstract] [PDF]  

T Wang, X Chen, RL Schecter, S Baruchel, M Alaoui-Jamali, D Melnychuk, and G Batist

Modulation of glutathione by a cysteine pro-drug enhances in vivo tumor response
J Pharmacol Exp Ther 1996 276: 1169-1173. [Abstract] [PDF]  

GB Glavin, S Szabo, BR Johnson, PL Xing, RE Morales, M Plebani, and L Nagy

Isolated rat gastric mucosal cells: optimal conditions for cell harvesting, measures of viability and direct cytoprotection
J Pharmacol Exp Ther 1996 276: 1174-1179. [Abstract] [PDF]  

RH Schwinger, J Muller-Ehmsen, M Bohm, and E Erdmann

Enantioselective inotropic actions of the Na+-channel activators BDF 9148, BDF 9196 and BDF 9167 in human failing and nonfailing myocardium
J Pharmacol Exp Ther 1996 276: 1180-1188. [Abstract] [PDF]  

KD Adkison and DD Shen

Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter
J Pharmacol Exp Ther 1996 276: 1189-1200. [Abstract] [PDF]  

TA Thompson, JM Lewis, NS Dejneka, WB Severs, R Polavarapu, and ML Billingsley

Induction of apoptosis by organotin compounds in vitro: neuronal protection with antisense oligonucleotides directed against stannin
J Pharmacol Exp Ther 1996 276: 1201-1216. [Abstract] [PDF]  

J Liu, Y Liu, AE Michalska, KH Choo, and CD Klaassen

Metallothionein plays less of a protective role in cadmium- metallothionein-induced nephrotoxicity than in cadmium chloride-induced hepatotoxicity
J Pharmacol Exp Ther 1996 276: 1216-1223. [Abstract] [PDF]  

BM Taylor, WE Fleming, CW Benjamin, Y Wu, WR Mathews, and FF Sun

The mechanism of cytoprotective action of lazaroids I: Inhibition of reactive oxygen species formation and lethal cell injury during periods of energy depletion
J Pharmacol Exp Ther 1996 276: 1224-1231. [Abstract] [PDF]  

D Bustamante, C Paeile, JC Willer, and D Le Bars

Effects of intravenous nonsteroidal antiinflammatory drugs on a C-fiber reflex elicited by a wide range of stimulus intensities in the rat
J Pharmacol Exp Ther 1996 276: 1232-1243. [Abstract] [PDF]  

MS Reid, K Hsu, BK Tolliver, CA Crawford, and SP Berger

Evidence for the involvement of phospholipase A2 mechanisms in the development of stimulant sensitization
J Pharmacol Exp Ther 1996 276: 1244-1256. [Abstract] [PDF]  

TC Jeong, SD Jordan, RA Matulka, ED Stanulis, SS Park, and MP Holsapple

Immunosuppression induced by acute exposure to cocaine is dependent on metabolism by cytochrome P-450
J Pharmacol Exp Ther 1996 276: 1257-1265. [Abstract] [PDF]  

M Ali, AZ Gawin, and JN Baraniuk

Effects of bombesin family peptides and antagonists on guinea pig nasal mucosal secretion
J Pharmacol Exp Ther 1996 276: 1266-1271. [Abstract] [PDF]  

S Regunathan, C Youngson, W Raasch, H Wang, and DJ Reis

Imidazoline receptors and agmatine in blood vessels: a novel system inhibiting vascular smooth muscle proliferation
J Pharmacol Exp Ther 1996 276: 1272-1282. [Abstract] [PDF]  

PH Wu, JF Liu, WL Wu, AJ Lanca, and H Kalant

Development of alcohol tolerance in the rat after a single exposure to combined treatment with arginine8-vasopressin and ethanol
J Pharmacol Exp Ther 1996 276: 1283-1291. [Abstract] [PDF]  

D Simms and JP Gallagher

Modification of serotonin responses in rat dorsolateral septal nucleus neurons by acute and chronic cocaine
J Pharmacol Exp Ther 1996 276: 1292-1303. [Abstract] [PDF]  

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