ARTICLES:

SH Graham, J Chen, JQ Lan, and RP Simon

A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia
J Pharmacol Exp Ther 1996 276: 1-4. [Abstract] [PDF]  

G Endemann, Y Feng, CM Bryant, GS Hamilton, J Perumattam, RE Mewshaw, and DY Liu

Novel anti-inflammatory compounds prevent CD11b/CD18, alpha M beta 2 (Mac-1)-dependent neutrophil adhesion without blocking activation- induced changes in Mac-1
J Pharmacol Exp Ther 1996 276: 5-12. [Abstract] [PDF]  

SP Tofovic and EK Jackson

Tachyphylaxis to angiotensin II and [Phe4]-angiotensin II in the rat mesentery in vivo
J Pharmacol Exp Ther 1996 276: 13-20. [Abstract] [PDF]  

J Thornton-Manning, ML Appleton, FJ Gonzalez, and GS Yost

Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding
J Pharmacol Exp Ther 1996 276: 21-29. [Abstract] [PDF]  

A Rengasamy and RA Johns

Determination of Km for oxygen of nitric oxide synthase isoforms
J Pharmacol Exp Ther 1996 276: 30-33. [Abstract] [PDF]  

RD Trifunovic and MS Brodie

The effects of clomipramine on the excitatory action of ethanol on dopaminergic neurons of the ventral tegmental area in vitro
J Pharmacol Exp Ther 1996 276: 34-40. [Abstract] [PDF]  

GD Bartoszyk, J Harting, and KO Minck

Roxindole: psychopharmacological profile of a dopamine D2 autoreceptor agonist
J Pharmacol Exp Ther 1996 276: 41-48. [Abstract] [PDF]  

N Hotta, N Koh, F Sakakibara, J Nakamura, Y Hamada, T Wakao, T Hara, K Mori, K Naruse, E Nakashima, and N Sakamoto

Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin- induced diabetes: comparison with an aldose reductase inhibitor
J Pharmacol Exp Ther 1996 276: 49-55. [Abstract] [PDF]  

F Rodriguez de Fonseca, P Rubio, F Menzaghi, E Merlo-Pich, J Rivier, GF Koob, and M Navarro

Corticotropin-releasing factor (CRF) antagonist [D-Phe12,Nle21,38,C alpha MeLeu37]CRF attenuates the acute actions of the highly potent cannabinoid receptor agonist HU-210 on defensive-withdrawal behavior in rats
J Pharmacol Exp Ther 1996 276: 56-64. [Abstract] [PDF]  

PJ Monroe, AA Hawranko, DL Smith, and DJ Smith

Biochemical and pharmacological characterization of multiple beta- endorphinergic antinociceptive systems in the rat periaqueductal gray
J Pharmacol Exp Ther 1996 276: 65-73. [Abstract] [PDF]  

MH Chin, CL Cioffi, M Garay, RF Neale, SS Shetty, D DelGrande, B Mugrage, MA Sills, and KE Lipson

The unusual binding properties of the endothelin receptor antagonist CGS 27830 distinguishes receptor/agonist interactions
J Pharmacol Exp Ther 1996 276: 74-83. [Abstract] [PDF]  

M Shimizu-Sasamata, S Kawasaki-Yatsugi, M Okada, S Sakamoto, S Yatsugi, J Togami, K Hatanaka, J Ohmori, K Koshiya, S Usuda, and K Murase

YM90K: pharmacological characterization as a selective and potent alpha- amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist
J Pharmacol Exp Ther 1996 276: 84-92. [Abstract] [PDF]  

BF King, J Pintor, S Wang, AU Ziganshin, LE Ziganshina, and G Burnstock

A novel P1 purinoceptor activates an outward K+ current in follicular oocytes of Xenopus laevis
J Pharmacol Exp Ther 1996 276: 93-100. [Abstract] [PDF]  

W Tassaneeyakul, DJ Birkett, JW Edwards, ME Veronese, W Tassaneeyakul, RH Tukey, and JO Miners

Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene
J Pharmacol Exp Ther 1996 276: 101-108. [Abstract] [PDF]  

JX Mazoit, LS Cao, and K Samii

Binding of bupivacaine to human serum proteins, isolated albumin and isolated alpha-1-acid glycoprotein. Differences between the two enantiomers are partly due to cooperativity
J Pharmacol Exp Ther 1996 276: 109-115. [Abstract] [PDF]  

YB Peng, Q Lin, and WD Willis

The role of 5-HT3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats
J Pharmacol Exp Ther 1996 276: 116-124. [Abstract] [PDF]  

RM Edwards, W Trizna, EJ Stack, and J Weinstock

Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes
J Pharmacol Exp Ther 1996 276: 125-129. [Abstract] [PDF]  

LD Khac, S Arnaudeau, N Lepretre, J Mironneau, and S Harbon

Beta adrenergic receptor activation attenuates the generation of inositol phosphates in the pregnant rat myometrium. Correlation with inhibition of Ca++ influx, a cAMP-independent mechanism
J Pharmacol Exp Ther 1996 276: 130-136. [Abstract] [PDF]  

PB Osborne and MJ Christie

Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons
J Pharmacol Exp Ther 1996 276: 137-142. [Abstract] [PDF]  

CJ Hough, RP Irwin, XM Gao, MA Rogawski, and DM Chuang

Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells
J Pharmacol Exp Ther 1996 276: 143-149. [Abstract] [PDF]  

K Shiosaki, P Jenner, KE Asin, DR Britton, CW Lin, M Michaelides, L Smith, B Bianchi, S Didomenico, L Hodges, Y Hong, L Mahan, J Mikusa, T Miller, A Nikkel, M Stashko, D Witte, and M Williams

ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease
J Pharmacol Exp Ther 1996 276: 150-160. [Abstract] [PDF]  

S Subramaniam, SD Donevan, and MA Rogawski

Block of the N-methyl-D-aspartate receptor by remacemide and its des- glycine metabolite
J Pharmacol Exp Ther 1996 276: 161-168. [Abstract] [PDF]  

Y Xie, T McHugh, J McKay, GS Jr Jones, and RH Loring

Evidence that a nereistoxin metabolite, and not nereistoxin itself, reduces neuronal nicotinic receptors: studies in the whole chick ciliary ganglion, on isolated neurons and immunoprecipitated receptors
J Pharmacol Exp Ther 1996 276: 169-177. [Abstract] [PDF]  

X Liu and JM Farley

Acetylcholine-induced chloride current oscillations in swine tracheal smooth muscle cells
J Pharmacol Exp Ther 1996 276: 178-186. [Abstract] [PDF]  

M Hatch, RW Freel, S Shahinfar, and ND Vaziri

Effects of the specific angiotensin II receptor antagonist losartan on urate homeostasis and intestinal urate transport
J Pharmacol Exp Ther 1996 276: 187-193. [Abstract] [PDF]  

LH Lash, JJ Tokarz, Z Chen, BM Pedrosi, and EB Woods

ATP depletion by iodoacetate and cyanide in renal distal tubular cells
J Pharmacol Exp Ther 1996 276: 194-205. [Abstract] [PDF]  

D Wu, RJ Boado, and WM Pardridge

Pharmacokinetics and blood-brain barrier transport of [3H]-biotinylated phosphorothioate oligodeoxynucleotide conjugated to a vector-mediated drug delivery system
J Pharmacol Exp Ther 1996 276: 206-211. [Abstract] [PDF]  

B Conte, C Cutrufo, and S Manzini

Electrocorticographic desynchronization after application of visceral and somatic noxious stimuli in urethane-anesthetized rats: effect of intrathecal administration of tachykinin (NK 1 or NK 2) receptor antagonists
J Pharmacol Exp Ther 1996 276: 212-218. [Abstract] [PDF]  

EM van der Aa, AC Wouterse, CE Verrijt, JH Peereboom-Stegeman, and FG Russel

Uptake of cimetidine into syncytial microvillus membrane vesicles of human term placenta
J Pharmacol Exp Ther 1996 276: 219-222. [Abstract] [PDF]  

P Bouchard, F Roman, JL Junien, and R Quirion

Autoradiographic evidence for the modulation of in vivo sigma receptor labeling by neuropeptide Y and calcitonin gene-related peptide in the mouse brain
J Pharmacol Exp Ther 1996 276: 223-230. [Abstract] [PDF]  

K Saita, T Ohi, Y Hanaoka, S Furukawa, Y Furukawa, K Hayashi, and S Matsukura

A catechol derivative (4-methylcatechol) accelerates the recovery from experimental acrylamide-induced neuropathy
J Pharmacol Exp Ther 1996 276: 231-237. [Abstract] [PDF]  

JS Sidhu and CJ Omiecinski

Forskolin-mediated induction of CYP3A1 mRNA expression in primary rat hepatocytes is independent of elevated intracellular cyclic AMP
J Pharmacol Exp Ther 1996 276: 238-245. [Abstract] [PDF]  

WM Pardridge, YS Kang, A Diagne, and JA Zack

Cationized hyperimmune immunoglobulins: pharmacokinetics, toxicity evaluation and treatment of human immunodeficiency virus-infected human- peripheral blood lymphocytes-severe combined immune deficiency mice
J Pharmacol Exp Ther 1996 276: 246-252. [Abstract] [PDF]  

LY Chen and JL Mehta

Variable effects of L-arginine analogs on L-arginine-nitric oxide pathway in human neutrophils and platelets may relate to different nitric oxide synthase isoforms
J Pharmacol Exp Ther 1996 276: 253-257. [Abstract] [PDF]  

JC Kraner, ET Morgan, TS Poet, SL Born, VL Burnett, and JR Halpert

Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity
J Pharmacol Exp Ther 1996 276: 258-264. [Abstract] [PDF]  

G Yue, FF Sun, C Dunn, K Yin, and PY Wong

The 21-aminosteroid tirilazad mesylate can ameliorate inflammatory bowel disease in rats
J Pharmacol Exp Ther 1996 276: 265-270. [Abstract] [PDF]  

CP Peter, J Guy, M Shea, W Bagdon, WF Kline, and WC Hayes

Long-term safety of the aminobisphosphonate alendronate in adult dogs. I. General safety and biomechanical properties of bone
J Pharmacol Exp Ther 1996 276: 271-276. [Abstract] [PDF]  

R Balena, A Markatos, JG Seedor, M Gentile, C Stark, CP Peter, and GA Rodan

Long-term safety of the aminobisphosphonate alendronate in adult dogs. II. Histomorphometric analysis of the L5 vertebrae
J Pharmacol Exp Ther 1996 276: 277-283. [Abstract] [PDF]  

T Hussain, J Linden, and SJ Mustafa

125I-APE binding to adenosine receptors in coronary artery: photoaffinity labeling with 125I-azidoAPE
J Pharmacol Exp Ther 1996 276: 284-288. [Abstract] [PDF]  

M Gopalakrishnan, LM Monteggia, DJ Anderson, EJ Molinari, M Piattoni-Kaplan, D Donnelly-Roberts, SP Arneric, and JP Sullivan

Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor
J Pharmacol Exp Ther 1996 276: 289-297. [Abstract] [PDF]  

JB McMahon, RW Jr Buckheit, RJ Gulakowski, MJ Currens, DT Vistica, RH Shoemaker, SF Stinson, JD Russell, JP Bader, VL Narayanan, RJ Schultz, WG Brouwer, EE Felauer, and MR Boyd

Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor
J Pharmacol Exp Ther 1996 276: 298-305. [Abstract] [PDF]  

KL Widnell, DW Self, SB Lane, DS Russell, VA Vaidya, MJ Miserendino, CS Rubin, RS Duman, and EJ Nestler

Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens
J Pharmacol Exp Ther 1996 276: 306-315. [Abstract] [PDF]  

X Tao, LS Davis, K Hashimoto, and PE Lipsky

The Chinese herbal remedy, T2, inhibits mitogen-induced cytokine gene transcription by T cells, but not initial signal transduction
J Pharmacol Exp Ther 1996 276: 316-325. [Abstract] [PDF]  

DJ Hnatowich, G Mardirossian, M Fogarasi, T Sano, CL Smith, CR Cantor, M Rusckowski, and P Jr Winnard

Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in mice
J Pharmacol Exp Ther 1996 276: 326-334. [Abstract] [PDF]  

G Rossoni, A Sala, F Berti, T Testa, C Buccellati, C Molta, R Muller- Peddinghaus, J Maclouf, and GC Folco

Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes
J Pharmacol Exp Ther 1996 276: 335-341. [Abstract] [PDF]  

DG Standaert, CM Testa, GD Rudolf, and ZR Hollingsworth

Inhibition of N-methyl-D-aspartate glutamate receptor subunit expression by antisense oligonucleotides reveals their role in striatal motor regulation
J Pharmacol Exp Ther 1996 276: 342-352. [Abstract] [PDF]  

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