ARTICLES:

M Lee, KH Yang, and NE Kaminski

Effects of putative cannabinoid receptor ligands, anandamide and 2- arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes
J Pharmacol Exp Ther 1995 275: 529-536. [Abstract] [PDF]  

A Takagi, H Masuda, Y Takakura, and M Hashida

Disposition characteristics of recombinant human interleukin-11 after a bolus intravenous administration in mice
J Pharmacol Exp Ther 1995 275: 537-543. [Abstract] [PDF]  

AA Larson and KF Kitto

Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide
J Pharmacol Exp Ther 1995 275: 544-550. [Abstract] [PDF]  

HS Kim and WK Park

Nitric oxide mediation of cocaine-induced dopaminergic behaviors: ambulation-accelerating activity, reverse tolerance and conditioned place preference in mice
J Pharmacol Exp Ther 1995 275: 551-557. [Abstract] [PDF]  

TE Jonassen, L Gronbeck, M Shalmi, JS Petersen, F Andreasen, and S Christensen

Supra-additive natriuretic synergism between bendroflumethiazide and furosemide in rats
J Pharmacol Exp Ther 1995 275: 558-565. [Abstract] [PDF]  

DS Sonnichsen, Q Liu, EG Schuetz, JD Schuetz, A Pappo, and MV Relling

Variability in human cytochrome P450 paclitaxel metabolism
J Pharmacol Exp Ther 1995 275: 566-575. [Abstract] [PDF]  

L Zhang and XQ Hu

Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state
J Pharmacol Exp Ther 1995 275: 576-583. [Abstract] [PDF]  

G Abou-Mohamed, A Papapetropoulos, D Ulrich, JD Catravas, RR Tuttle, and RW Caldwell

HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro
J Pharmacol Exp Ther 1995 275: 584-591. [Abstract] [PDF]  

J Schmider, DJ Greenblatt, LL von Moltke, JS Harmatz, and RI Shader

N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors
J Pharmacol Exp Ther 1995 275: 592-597. [Abstract] [PDF]  

CE Tedford, SL Yates, GP Pawlowski, JW Nalwalk, LB Hough, MA Khan, JG Phillips, GJ Durant, and RC Frederickson

Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies
J Pharmacol Exp Ther 1995 275: 598-604. [Abstract] [PDF]  

RB Parker, CL Williams, SC Laizure, and JJ Lima

Factors affecting serum protein binding of cocaine in humans
J Pharmacol Exp Ther 1995 275: 605-610. [Abstract] [PDF]  

PK Rangachari, PA Betti, ET Prior, and LJ 2nd Roberts

Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?
J Pharmacol Exp Ther 1995 275: 611-617. [Abstract] [PDF]  

V Neugebauer, G Geisslinger, P Rumenapp, F Weiretter, I Szelenyi, K Brune, and HG Schaible

Antinociceptive effects of R(-)- and S(+)-flurbiprofen on rat spinal dorsal horn neurons rendered hyperexcitable by an acute knee joint inflammation
J Pharmacol Exp Ther 1995 275: 618-628. [Abstract] [PDF]  

F Guirimand, M Chauvin, JC Willer, and D Le Bars

Effects of intrathecal and intracerebroventricular buprenorphine on a C- fiber reflex in the rat
J Pharmacol Exp Ther 1995 275: 629-637. [Abstract] [PDF]  

MM Usowicz, M Gigg, LM Jones, CW Cheung, and SA Hartley

Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644
J Pharmacol Exp Ther 1995 275: 638-645. [Abstract] [PDF]  

AA Houdi, RT Dowell, and JN Diana

Cardiovascular responses to cigarette smoke exposure in restrained conscious rats
J Pharmacol Exp Ther 1995 275: 646-653. [Abstract] [PDF]  

HJ Kim, JH Cho, and CD Klaassen

Depletion of hepatic 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and sulfate in rats by xenobiotics that are sulfated
J Pharmacol Exp Ther 1995 275: 654-658. [Abstract] [PDF]  

L Simon, B Ghaleh, L Puybasset, JF Giudicelli, and A Berdeaux

Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs
J Pharmacol Exp Ther 1995 275: 659-666. [Abstract] [PDF]  

S Cardin, AH Soll, and Y Tache

Different effects of indomethacin and nabumetone on prostaglandin- mediated gastric responses to central vagal activation in rats
J Pharmacol Exp Ther 1995 275: 667-673. [Abstract] [PDF]  

H Chen, H Li, and DM Chuang

Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: involvement of calcium influx and a calmodulin-dependent pathway
J Pharmacol Exp Ther 1995 275: 674-680. [Abstract] [PDF]  

M Gollasch, R Bychkov, C Ried, F Behrendt, S Scholze, FC Luft, and H Haller

Pinacidil relaxes porcine and human coronary arteries by activating ATP- dependent potassium channels in smooth muscle cells
J Pharmacol Exp Ther 1995 275: 681-692. [Abstract] [PDF]  

C Rundfeldt, P Wlaz, D Honack, and W Loscher

Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil
J Pharmacol Exp Ther 1995 275: 693-702. [Abstract] [PDF]  

RE Howell, LP Jenkins, and DE Howell

Inhibition of lipopolysaccharide-induced pulmonary edema by isozyme- selective phosphodiesterase inhibitors in guinea pigs
J Pharmacol Exp Ther 1995 275: 703-709. [Abstract] [PDF]  

J Ren, E Karpinski, and CG Benishin

Prostaglandin E2 contracts vascular smooth muscle and inhibits potassium currents in vascular smooth muscle cells of rat tail artery
J Pharmacol Exp Ther 1995 275: 710-719. [Abstract] [PDF]  

DC Deecher, OO Odusan, and EJ Mufson

Galanin receptors in human basal forebrain differ from receptors in the hypothalamus: characterization using [125I]galanin (porcine) and [125I]galantide
J Pharmacol Exp Ther 1995 275: 720-727. [Abstract] [PDF]  

M Suzuki, T Yamaguchi, Y Ozawa, M Ohyama, and M Yamamoto

Effects of (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L- tartrate monohydrate (YM796), a novel muscarinic agonist, on disturbance of passive avoidance learning behavior in drug-treated and senescence-accelerated mice
J Pharmacol Exp Ther 1995 275: 728-736. [Abstract] [PDF]  

BD Gitter, RF Bruns, JJ Howbert, DC Waters, PG Threlkeld, LM Cox, JA Nixon, KL Lobb, NR Mason, and PW Stengel

Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist
J Pharmacol Exp Ther 1995 275: 737-744. [Abstract] [PDF]  

NC Trippodo, JA Robl, MM Asaad, JE Bird, BC Panchal, TR Schaeffer, M Fox, MR Giancarli, and HS Cheung

Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure
J Pharmacol Exp Ther 1995 275: 745-752. [Abstract] [PDF]  

P Popik, RT Layer, LH Fossom, M Benveniste, B Geter-Douglass, JM Witkin, and P Skolnick

NMDA antagonist properties of the putative antiaddictive drug, ibogaine
J Pharmacol Exp Ther 1995 275: 753-760. [Abstract] [PDF]  

AH Tang, MW Smith, DB Carter, WB Im, and PF VonVoigtlander

U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes
J Pharmacol Exp Ther 1995 275: 761-767. [Abstract] [PDF]  

J Liu, Y Liu, A Parkinson, and CD Klaassen

Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice
J Pharmacol Exp Ther 1995 275: 768-774. [Abstract] [PDF]  

M Asano, Y Nomura, K Ito, Y Uyama, Y Imaizumi, and M Watanabe

Increased function of voltage-dependent Ca++ channels and Ca(++)- activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage
J Pharmacol Exp Ther 1995 275: 775-783. [Abstract] [PDF]  

R Yu and MK Ticku

Chronic neurosteroid treatment decreases the efficacy of benzodiazepine ligands and neurosteroids at the gamma-aminobutyric acidA receptor complex in mammalian cortical neurons
J Pharmacol Exp Ther 1995 275: 784-789. [Abstract] [PDF]  

AJ Roberts, CN Lessov, and TJ Phillips

Critical role for glucocorticoid receptors in stress- and ethanol- induced locomotor sensitization
J Pharmacol Exp Ther 1995 275: 790-797. [Abstract] [PDF]  

PK Gonzalez, J Zhuang, SR Doctrow, B Malfroy, PF Benson, MJ Menconi, and MP Fink

EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine
J Pharmacol Exp Ther 1995 275: 798-806. [Abstract] [PDF]  

YG Kwak, SK Park, HS Kang, JS Kim, SW Chae, KP Cho, SE Yoo, and D Kim

KR-30450, a newly synthesized benzopyran derivative, activates the cardiac ATP-sensitive K+ channel
J Pharmacol Exp Ther 1995 275: 807-812. [Abstract] [PDF]  

N Hayase, S Inagaki, and Y Abiko

Effects of photodegradation products of nifedipine: the nitroso- derivative relaxes contractions of the rat aortic strip induced by norepinephrine and other agonists
J Pharmacol Exp Ther 1995 275: 813-821. [Abstract] [PDF]  

R Schreiber, M Brocco, B Lefebvre de Ladonchamps, S Monneyron, and MJ Millan

A drug discrimination analysis of the actions of novel serotonin1A receptor ligands in the rat using the 5-HT1A receptor agonist, 8- hydroxy-2-(di-n-propylamino)tetralin
J Pharmacol Exp Ther 1995 275: 822-831. [Abstract] [PDF]  

M Kahonen, PA Doris, H Makynen, and I Porsti

Plasma digoxin immunoreactivity and arterial potassium relaxation after quinapril therapy in hypertensive rats
J Pharmacol Exp Ther 1995 275: 832-837. [Abstract] [PDF]  

DM Mooney, B Hu, and VV Senatorov

Muscarine induces an anomalous inhibition of synaptic transmission in rat auditory thalamic neurons in vitro
J Pharmacol Exp Ther 1995 275: 838-844. [Abstract] [PDF]  

L Steardo, P Monteleone, M d'Istria, I Serino, M Maj, and V Cuomo

(+)-N-allylnormetazocine enhances N-acetyltransferase activity and melatonin synthesis: preliminary evidence for a functional role of sigma receptors in the rat pineal gland
J Pharmacol Exp Ther 1995 275: 845-849. [Abstract] [PDF]  

F Buttgereit, I Brink, B Thiele, GR Burmester, F Hiepe, and ED Hall

Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells
J Pharmacol Exp Ther 1995 275: 850-853. [Abstract] [PDF]  

O Edling, G Bao, M Feelisch, T Unger, and P Gohlke

Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril
J Pharmacol Exp Ther 1995 275: 854-863. [Abstract] [PDF]  

R Bouchard and D Fedida

Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5
J Pharmacol Exp Ther 1995 275: 864-876. [Abstract] [PDF]  

J Wang and KM Johnson

Regulation of striatal cyclic-3',5'-adenosine monophosphate accumulation and GABA release by glutamate metabotropic and dopamine D1 receptors
J Pharmacol Exp Ther 1995 275: 877-884. [Abstract] [PDF]  

MJ Millan, JL Peglion, J Vian, JM Rivet, M Brocco, A Gobert, A Newman-Tancredi, C Dacquet, K Bervoets, and S Girardon

Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy
J Pharmacol Exp Ther 1995 275: 885-898. [Abstract] [PDF]  

A Gobert, JM Rivet, V Audinot, L Cistarelli, M Spedding, J Vian, JL Peglion, and MJ Millan

Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways
J Pharmacol Exp Ther 1995 275: 899-913. [Abstract] [PDF]  

C Casati, A Monopoli, A Forlani, E Bonizzoni, and E Ongini

Telemetry monitoring of hemodynamic effects induced over time by adenosine agonists in spontaneously hypertensive rats
J Pharmacol Exp Ther 1995 275: 914-919. [Abstract] [PDF]  

K Ito, K Ito, Y Sawada, J Kamei, M Misawa, and T Iga

Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig
J Pharmacol Exp Ther 1995 275: 920-925. [Abstract] [PDF]  

CE Groves, MN Morales, AJ Gandolfi, WH Dantzler, and SH Wright

Peritubular paraquat transport in isolated renal proximal tubules
J Pharmacol Exp Ther 1995 275: 926-932. [Abstract] [PDF]  

C Chou, AJ McLachlan, and M Rowland

Membrane permeability and lipophilicity in the isolated perfused rat liver: 5-ethyl barbituric acid and other compounds
J Pharmacol Exp Ther 1995 275: 933-940. [Abstract] [PDF]  

CF Toombs, GL DeGraaf, JP Martin, JG Geng, DC Anderson, and RJ Shebuski

Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis
J Pharmacol Exp Ther 1995 275: 941-949. [Abstract] [PDF]  

YC Han and SB Pruett

Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking
J Pharmacol Exp Ther 1995 275: 950-957. [Abstract] [PDF]  

T Lindmark, T Nikkila, and P Artursson

Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers
J Pharmacol Exp Ther 1995 275: 958-964. [Abstract] [PDF]  

RA Dean, J Zhang, MR Brzezinski, and WF Bosron

Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein
J Pharmacol Exp Ther 1995 275: 965-971. [Abstract] [PDF]  

M Shimada, N Murayama, Y Yamazoe, H Hashimoto, H Ishikawa, and R Kato

Age- and sex-related alterations of microsomal drug- and testosterone- oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats
J Pharmacol Exp Ther 1995 275: 972-977. [Abstract] [PDF]  

EE Daniel, V Gaspar, I Berezin, and CY Kwan

Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons
J Pharmacol Exp Ther 1995 275: 978-986. [Abstract] [PDF]  

M Bencherif, K Fowler, RJ Lukas, and PM Lippiello

Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain
J Pharmacol Exp Ther 1995 275: 987-994. [Abstract] [PDF]  

PB Jacobson, SL Kuchera, A Metz, C Schachtele, K Imre, and DJ Schrier

Anti-inflammatory properties of Go 6850: a selective inhibitor of protein kinase C
J Pharmacol Exp Ther 1995 275: 995-1002. [Abstract] [PDF]  

MJ Picklo, RG Wiley, S Lonce, DA Lappi, and D Robertson

Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats
J Pharmacol Exp Ther 1995 275: 1003-1010. [Abstract] [PDF]  

EG Schuetz, KN Furuya, and JD Schuetz

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms
J Pharmacol Exp Ther 1995 275: 1011-1018. [Abstract] [PDF]  

RC Pierce and PW Kalivas

Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine
J Pharmacol Exp Ther 1995 275: 1019-1029. [Abstract] [PDF]  

DC Perry and KJ Kellar

[3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study
J Pharmacol Exp Ther 1995 275: 1030-1034. [Abstract] [PDF]  

MA Scofield, F Liu, PW Abel, and WB Jeffries

Quantification of steady state expression of mRNA for alpha-1 adrenergic receptor subtypes using reverse transcription and a competitive polymerase chain reaction
J Pharmacol Exp Ther 1995 275: 1035-1042. [Abstract] [PDF]  

HM Cherwinski, RG Cohn, P Cheung, DJ Webster, YZ Xu, JP Caulfield, JM Young, G Nakano, and JT Ransom

The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis
J Pharmacol Exp Ther 1995 275: 1043-1049. [Abstract] [PDF]  

RL Smith, RJ Barrett, and E Sanders-Bush

Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor
J Pharmacol Exp Ther 1995 275: 1050-1057. [Abstract] [PDF]  

LW Liu, L Thuneberg, and JD Huizinga

Cyclopiazonic acid, inhibiting the endoplasmic reticulum calcium pump, reduces the canine colonic pacemaker frequency
J Pharmacol Exp Ther 1995 275: 1058-1068. [Abstract] [PDF]  

M Visentin, R Bellasio, and MT Tacconi

Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine
J Pharmacol Exp Ther 1995 275: 1069-1075. [Abstract] [PDF]  

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