ARTICLES:

ML Pucci, LB Dick, KB Miller, CJ Smith, and A Nasjletti

Enhanced responses to L-arginine in aortic rings from rats with angiotensin-dependent hypertension
J Pharmacol Exp Ther 1995 274: 1-7. [Abstract] [PDF]  

JY Xu and LF Tseng

Nitric oxide/cyclic guanosine monophosphate system in the spinal cord differentially modulates intracerebroventricularly administered morphine- and beta-endorphin-induced antinociception in the mouse
J Pharmacol Exp Ther 1995 274: 8-16. [Abstract] [PDF]  

CP France, LR Gerak, D Flynn, GD Winger, F Medzihradsky, JR Bagley, LL Brockunier, and JH Woods

Behavioral effects and receptor binding affinities of fentanyl derivatives in rhesus monkeys
J Pharmacol Exp Ther 1995 274: 17-28. [Abstract] [PDF]  

DM Ford, RE Thieme, CA Lamp, SJ Covington, and BA Molitoris

HWA-448 reduces gentamicin toxicity in LLC-PK1 cells
J Pharmacol Exp Ther 1995 274: 29-33. [Abstract] [PDF]  

HM Amin, AM Sopchak, BF Esposito, LG Henson, RL Batenhorst, AW Fox, and EM Camporesi

Naloxone-induced and spontaneous reversal of depressed ventilatory responses to hypoxia during and after continuous infusion of remifentanil or alfentanil
J Pharmacol Exp Ther 1995 274: 34-39. [Abstract] [PDF]  

I Nakae, M Takahashi, T Kinoshita, T Matsumoto, and M Kinoshita

The effects of S-nitrosocaptopril on canine coronary circulation
J Pharmacol Exp Ther 1995 274: 40-46. [Abstract] [PDF]  

GC Wellman and JA Bevan

Barium inhibits the endothelium-dependent component of flow but not acetylcholine-induced relaxation in isolated rabbit cerebral arteries
J Pharmacol Exp Ther 1995 274: 47-53. [Abstract] [PDF]  

L Lacinova, A Welling, E Bosse, P Ruth, V Flockerzi, and F Hofmann

Interaction of Ro 40-5967 and verapamil with the stably expressed alpha 1-subunit of the cardiac L-type calcium channel
J Pharmacol Exp Ther 1995 274: 54-63. [Abstract] [PDF]  

V Ralevic, P Karoon, and G Burnstock

Long-term sensory denervation by neonatal capsaicin treatment augments sympathetic neurotransmission in rat mesenteric arteries by increasing levels of norepinephrine and selectively enhancing postjunctional actions
J Pharmacol Exp Ther 1995 274: 64-71. [Abstract] [PDF]  

JM Goldhill, FD Finkelman, SC Morris, and T Shea-Donohue

Neural control of mouse small intestinal longitudinal muscle: interactions with inflammatory mediators
J Pharmacol Exp Ther 1995 274: 72-77. [Abstract] [PDF]  

RR Nadeau, C Ostrowski, G Ni-Wu, and DJ Liberato

Pharmacokinetics and pharmacodynamics of recombinant human interleukin- 12 in male rhesus monkeys
J Pharmacol Exp Ther 1995 274: 78-83. [Abstract] [PDF]  

CC Tenn and LP Niles

Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism
J Pharmacol Exp Ther 1995 274: 84-89. [Abstract] [PDF]  

WP Melega, AE Williams, DA Schmitz, EW DiStefano, and AK Cho

Pharmacokinetic and pharmacodynamic analysis of the actions of D- amphetamine and D-methamphetamine on the dopamine terminal
J Pharmacol Exp Ther 1995 274: 90-96. [Abstract] [PDF]  

SM Knepper, SA Buckner, ME Brune, JF DeBernardis, MD Meyer, and AA Hancock

A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype
J Pharmacol Exp Ther 1995 274: 97-103. [Abstract] [PDF]  

SN Tuzel-Kox, HM Patel, and WJ Kox

Uptake of drug-carrier liposomes by placenta: transplacental delivery of drugs and nutrients
J Pharmacol Exp Ther 1995 274: 104-109. [Abstract] [PDF]  

CB Washington, CM Brett, X Wu, and KM Giacomini

The effect of N-ethylmaleimide on the Na(+)-dependent nucleoside transporter (N3) in rabbit choroid plexus
J Pharmacol Exp Ther 1995 274: 110-114. [Abstract] [PDF]  

E Kuhls, IS Gauntlett, M Lau, R Brown, CD Rudolph, DF Teitel, and DM Fisher

Effect of increased intra-abdominal pressure on hepatic extraction and clearance of fentanyl in neonatal lambs
J Pharmacol Exp Ther 1995 274: 115-119. [Abstract] [PDF]  

A Sanbe and S Takeo

Effects of NKH477, a water-soluble forskolin derivative, on cardiac function in rats with chronic heart failure after myocardial infarction [published erratum appears in J Pharmacol Exp Ther 1996 Jan;276(1):352]
J Pharmacol Exp Ther 1995 274: 120-126. [Abstract] [PDF]  

A Pap and CW Bradberry

Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens
J Pharmacol Exp Ther 1995 274: 127-133. [Abstract] [PDF]  

NT Burford, AB Tobin, and SR Nahorski

Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells
J Pharmacol Exp Ther 1995 274: 134-142. [Abstract] [PDF]  

K Groen, DD Breimer, A Brouwer, G Schijff, EJ Jansen, and CF van Bezooijen

The influence of dietary restriction on the metabolism of theophylline and antipyrine in the ageing female BN/BiRij rat
J Pharmacol Exp Ther 1995 274: 143-147. [Abstract] [PDF]  

F Oury-Donat, P Carayon, O Thurneyssen, V Pailhon, X Emonds-Alt, P Soubrie, and G Le Fur

Functional characterization of the nonpeptide neurokinin3 (NK3) receptor antagonist, SR142801 on the human NK3 receptor expressed in Chinese hamster ovary cells
J Pharmacol Exp Ther 1995 274: 148-154. [Abstract] [PDF]  

M Mortensen, PD Suzdak, and C Thomsen

The effect of lorazepam tolerance and withdrawal on metabotropic glutamate receptor function
J Pharmacol Exp Ther 1995 274: 155-163. [Abstract] [PDF]  

DM Lovinger

Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: relation to the actions of ifenprodil
J Pharmacol Exp Ther 1995 274: 164-172. [Abstract] [PDF]  

A Bourson, E Borroni, RH Austin, FJ Jr Monsma, and AJ Sleight

Determination of the role of the 5-ht6 receptor in the rat brain: a study using antisense oligonucleotides
J Pharmacol Exp Ther 1995 274: 173-180. [Abstract] [PDF]  

SM Aziz, MP Gosland, PA Crooks, JW Olson, and MN Gillespie

A novel polymeric spermine conjugate inhibits polyamine transport in pulmonary artery smooth muscle cells
J Pharmacol Exp Ther 1995 274: 181-186. [Abstract] [PDF]  

N Sugihara, T Suetsugu, and K Furuno

High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid
J Pharmacol Exp Ther 1995 274: 187-193. [Abstract] [PDF]  

BM Tune and CY Hsu

Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates
J Pharmacol Exp Ther 1995 274: 194-199. [Abstract] [PDF]  

EA Konorev, MM Tarpey, J Joseph, JE Baker, and B Kalyanaraman

S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest-evidence for a cardioprotective effect of nitric oxide
J Pharmacol Exp Ther 1995 274: 200-206. [Abstract] [PDF]  

BE Garrett and SG Holtzman

Does adenosine receptor blockade mediate caffeine-induced rotational behavior?
J Pharmacol Exp Ther 1995 274: 207-214. [Abstract] [PDF]  

EF McCance, LH Price, TR Kosten, and PI Jatlow

Cocaethylene: pharmacology, physiology and behavioral effects in humans
J Pharmacol Exp Ther 1995 274: 215-223. [Abstract] [PDF]  

AI Sacaan, JL Dunlop, and GK Lloyd

Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices
J Pharmacol Exp Ther 1995 274: 224-230. [Abstract] [PDF]  

SM Florin, R Kuczenski, and DS Segal

Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations
J Pharmacol Exp Ther 1995 274: 231-241. [Abstract] [PDF]  

A Camins, E Escubedo, J Camarasa, J Carretero, AH Newman, and ME Kammuller

Dog neutrophil stimulation and cell surface expression of heat shock proteins induced by AHN 086
J Pharmacol Exp Ther 1995 274: 242-248. [Abstract] [PDF]  

ZH Zhang and MI Steinberg

LY 97241 accelerates the apparent rate of inactivation of transient outward K+ current: characterization of open channel block
J Pharmacol Exp Ther 1995 274: 249-257. [Abstract] [PDF]  

JH Todd and GH Hottendorf

Renal brush border membrane vesicle aminoglycoside binding and nephrotoxicity
J Pharmacol Exp Ther 1995 274: 258-263. [Abstract] [PDF]  

JH Lin, M Chiba, IW Chen, KJ Vastag, JA Nishime, BD Dorsey, SR Michelson, and SL McDaniel

Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys
J Pharmacol Exp Ther 1995 274: 264-269. [Abstract] [PDF]  

TK Chang, G Chen, and DJ Waxman

Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism
J Pharmacol Exp Ther 1995 274: 270-275. [Abstract] [PDF]  

AJ Eshleman, RL Neve, A Janowsky, and KA Neve

Characterization of a recombinant human dopamine transporter in multiple cell lines
J Pharmacol Exp Ther 1995 274: 276-283. [Abstract] [PDF]  

CM Handler, DJ Mondgock, SF Zhao, EB Geller, and MW Adler

Interaction between opioid agonists and neurotensin on thermoregulation in the rat. I. Body temperature
J Pharmacol Exp Ther 1995 274: 284-292. [Abstract] [PDF]  

NF Jensen and TD Egan

Defining the concentration-effect relationship of volatile anesthetics in vessels using an in vitro nonsteady-state technique
J Pharmacol Exp Ther 1995 274: 293-299. [Abstract] [PDF]  

KS Murthy, L McHenry, JR Grider, and GM Makhlouf

Adenosine A1 and A2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells
J Pharmacol Exp Ther 1995 274: 300-306. [Abstract] [PDF]  

W Loscher and D Honack

Anticonvulsant and antiepileptogenic effect of L-deprenyl (selegiline) in the kindling model of epilepsy
J Pharmacol Exp Ther 1995 274: 307-314. [Abstract] [PDF]  

T Yamashita, T Nakajima, E Hamada, H Hazama, M Omata, and Y Kurachi

Flecainide inhibits the transient outward current in atrial myocytes isolated from the rabbit heart
J Pharmacol Exp Ther 1995 274: 315-321. [Abstract] [PDF]  

P Holzer, W Schluet, and CA Maggi

Substance P stimulates and inhibits intestinal peristalsis via distinct receptors
J Pharmacol Exp Ther 1995 274: 322-328. [Abstract] [PDF]  

T Kikuchi, K Tottori, Y Uwahodo, T Hirose, T Miwa, Y Oshiro, and S Morita

7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl] butyloxy)-3,4-dihydro-2(1H)- quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity
J Pharmacol Exp Ther 1995 274: 329-336. [Abstract] [PDF]  

Y Odagaki and K Fuxe

Pharmacological characterization of the 5-hydroxytryptamine-1A receptor- mediated activation of high-affinity GTP hydrolysis in rat hippocampal membranes
J Pharmacol Exp Ther 1995 274: 337-344. [Abstract] [PDF]  

LJ Brunner, JT DiPiro, and S Feldman

Antipyrine pharmacokinetics in the tail-suspended rat model
J Pharmacol Exp Ther 1995 274: 345-352. [Abstract] [PDF]  

E Sanna, MP Mascia, RL Klein, PJ Whiting, G Biggio, and RA Harris

Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits
J Pharmacol Exp Ther 1995 274: 353-360. [Abstract] [PDF]  

SL Walsh, KL Preston, GE Bigelow, and ML Stitzer

Acute administration of buprenorphine in humans: partial agonist and blockade effects
J Pharmacol Exp Ther 1995 274: 361-372. [Abstract] [PDF]  

Y Taki, T Sakane, T Nadai, H Sezaki, GL Amidon, P Langguth, and S Yamashita

Gastrointestinal absorption of peptide drug: quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine
J Pharmacol Exp Ther 1995 274: 373-377. [Abstract] [PDF]  

GZ Dong, K Kameyama, A Rinken, and T Haga

Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells
J Pharmacol Exp Ther 1995 274: 378-384. [Abstract] [PDF]  

RB Rothman, ML Silverthorn, MH Baumann, CB Goodman, JL Cadet, D Matecka, KC Rice, FI Carroll, JB Wang, and GR Uhl

Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate
J Pharmacol Exp Ther 1995 274: 385-395. [Abstract] [PDF]  

SR Jones, PA Garris, and RM Wightman

Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens
J Pharmacol Exp Ther 1995 274: 396-403. [Abstract] [PDF]  

JM Rhoads, RA Argenzio, W Chen, and GG Gomez

Asparagine stimulates piglet intestinal Cl- secretion by a mechanism requiring a submucosal glutamate receptor and nitric oxide
J Pharmacol Exp Ther 1995 274: 404-412. [Abstract] [PDF]  

S Hoshida, N Yamashita, J Igarashi, M Nishida, M Hori, T Kamada, T Kuzuya, and M Tada

Nitric oxide synthase protects the heart against ischemia-reperfusion injury in rabbits
J Pharmacol Exp Ther 1995 274: 413-418. [Abstract] [PDF]  

J Sun and DJ Triggle

Calcium channel antagonists: cardiovascular selectivity of action
J Pharmacol Exp Ther 1995 274: 419-426. [Abstract] [PDF]  

AM Mayer, S Brenic, R Stocker, and KB Glaser

Modulation of superoxide generation in in vivo lipopolysaccharide- primed rat alveolar macrophages by arachidonic acid and inhibitors of protein kinase C, phospholipase A2, protein serine-threonine phosphatase(s), protein tyrosine kinase(s) and phosphatase(s)
J Pharmacol Exp Ther 1995 274: 427-436. [Abstract] [PDF]  

L Ratnakumari, IA Qureshi, D Maysinger, and RF Butterworth

Developmental deficiency of the cholinergic system in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine
J Pharmacol Exp Ther 1995 274: 437-443. [Abstract] [PDF]  

D Rampe, Z Wang, B Fermini, B Wible, RC Dage, and S Nattel

Voltage- and time-dependent block by perhexiline of K+ currents in human atrium and in cells expressing a Kv1.5-type cloned channel
J Pharmacol Exp Ther 1995 274: 444-449. [Abstract] [PDF]  

M Sala, D Braida, M Colombo, A Groppetti, S Sacco, E Gori, and M Parenti

Behavioral and biochemical evidence of opioidergic involvement in cocaine sensitization
J Pharmacol Exp Ther 1995 274: 450-457. [Abstract] [PDF]  

P Alberts

Classification of the presynaptic muscarinic receptor subtype that regulates 3H-acetylcholine secretion in the guinea pig urinary bladder in vitro
J Pharmacol Exp Ther 1995 274: 458-468. [Abstract] [PDF]  

R Sato, S Koumi, I Hisatome, H Takai, Y Aida, M Oyaizu, S Karasaki, H Mashiba, and R Katori

A new class III antiarrhythmic drug, MS-551, blocks the inward rectifier potassium channel in isolated guinea pig ventricular myocytes
J Pharmacol Exp Ther 1995 274: 469-474. [Abstract] [PDF]  

PY Wong, G Yue, K Yin, M Miyasaka, CL Lane, AM Manning, DC Anderson, and FF Sun

Antibodies to intercellular adhesion molecule-1 ameliorate the inflammatory response in acetic acid-induced inflammatory bowel disease
J Pharmacol Exp Ther 1995 274: 475-480. [Abstract] [PDF]  

H Karam, P Bruneval, JP Clozel, BM Loffler, J Bariety, and M Clozel

Role of endothelin in acute renal failure due to rhabdomyolysis in rats
J Pharmacol Exp Ther 1995 274: 481-486. [Abstract] [PDF]  

T Kanda, H Nagaoka, K Kaneko, JE Wilson, BM McManus, S Imai, T Suzuki, K Murata, and I Kobayashi

Synergistic effects of tacrolimus and human interferon-alpha A/D in murine viral myocarditis
J Pharmacol Exp Ther 1995 274: 487-493. [Abstract] [PDF]  

T Kanda, T Yokoyama, S Imai, T Suzuki, K Murata, and I Kobayashi

Effect of combination therapy with OK432 and recombinant human interferon-alpha A/D on atrial natriuretic peptide gene expression in mice with viral myocarditis
J Pharmacol Exp Ther 1995 274: 494-498. [Abstract] [PDF]  

JR Wu-Wong, WJ Chiou, SR Magnuson, and TJ Opgenorth

Endothelin receptor in human astrocytoma U373MG cells: binding, dissociation, receptor internalization
J Pharmacol Exp Ther 1995 274: 499-507. [Abstract] [PDF]  

HJ Duff, M Stemler, T Thannhauser, S Laganiere, E Rude, and W Lester

Proarrhythmia of a class Ic drug: suppression by combination with a drug prolonging repolarization in the dog late after infarction
J Pharmacol Exp Ther 1995 274: 508-515. [Abstract] [PDF]  

ML Dahl, I Johansson, L Bertilsson, M Ingelman-Sundberg, and F Sjoqvist

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis
J Pharmacol Exp Ther 1995 274: 516-520. [Abstract] [PDF]  

JY Wang, SA McCormack, MJ Viar, and LR Johnson

Inhibition of ornithine decarboxylase activity but not expression of the gene by cimetidine in intestinal mucosal cells
J Pharmacol Exp Ther 1995 274: 521-529. [Abstract] [PDF]  

J Neumann, S Herzig, P Boknik, M Apel, G Kaspareit, W Schmitz, H Scholz, M Tepel, and N Zimmermann

On the cardiac contractile, biochemical and electrophysiological effects of cantharidin, a phosphatase inhibitor
J Pharmacol Exp Ther 1995 274: 530-539. [Abstract] [PDF]  

DC McMillan, JV Simson, RA Budinsky, and DJ Jollow

Dapsone-induced hemolytic anemia: effect of dapsone hydroxylamine on sulfhydryl status, membrane skeletal proteins and morphology of human and rat erythrocytes
J Pharmacol Exp Ther 1995 274: 540-547. [Abstract] [PDF]  

DS Fletcher, DG Osinga, K Keenan, RJ Bonney, JB Doherty, PE Finke, SK Shah, and P Davies

An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung
J Pharmacol Exp Ther 1995 274: 548-554. [Abstract] [PDF]  

A Fujita, T Takeuchi, H Nakajima, H Nishio, and F Hata

Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens
J Pharmacol Exp Ther 1995 274: 555-561. [Abstract] [PDF]  

KL Dopke, KE Vrana, LJ Vogt, and BA Vogt

AF-DX 384 binding in rabbit cingulate cortex: two site kinetics and section autoradiography
J Pharmacol Exp Ther 1995 274: 562-569. [Abstract] [PDF]  

ML Donadoni, R Gavezzotti, F Borella, AM Di Giulio, and A Gorio

Experimental diabetic neuropathy. Inhibition of protein mono-ADP- ribosylation prevents reduction of substance P axonal transport
J Pharmacol Exp Ther 1995 274: 570-576. [Abstract] [PDF]  

M Allard, S Labrouche, A Nosjean, and R Laguzzi

Mechanisms underlying the cardiovascular responses to peripheral administration of NPFF in the rat
J Pharmacol Exp Ther 1995 274: 577-583. [Abstract] [PDF]  

H Takemura, J Tamaoki, E Tagaya, A Chiyotani, and K Konno

Isoproterenol increases Cl diffusion potential difference of rabbit trachea through nitric oxide generation
J Pharmacol Exp Ther 1995 274: 584-588. [Abstract] [PDF]  

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