ARTICLES:

B Cemerikic, R Zamah, and MS Ahmed

Opioid tolerance in human placenta due to in vitro methadone administration
J Pharmacol Exp Ther 1995 273: 987-994. [Abstract] [PDF]  

C Bonnafous, P Lefevre, and L Bueno

Benzodiazepine-withdrawal-induced gastric emptying disturbances in rats: evidence for serotonin receptor involvement
J Pharmacol Exp Ther 1995 273: 995-1000. [Abstract] [PDF]  

K Nomura, N Maeda, T Yoshino, and I Yamaguchi

Different mechanisms mediated by dopamine D1 and D2 receptors are involved etiologically in activity-stress gastric lesion of the rat
J Pharmacol Exp Ther 1995 273: 1001-1007. [Abstract] [PDF]  

A Botella, M Delvaux, J Fioramonti, J Frexinos, and L Bueno

Receptor subtypes involved in dual effects induced by prostaglandin E2 in circular smooth muscle from dog colon
J Pharmacol Exp Ther 1995 273: 1008-1014. [Abstract] [PDF]  

CE Pendley, LR Fitzpatrick, AJ Capolino, MA Davis, NJ Esterline, A Jakubowska, P Bertrand, C Guyon, MC Dubroeucq, and GE Martin

RP 73870, a gastrin/cholecystokinin-B receptor antagonist with potent anti-ulcer activity in the rat
J Pharmacol Exp Ther 1995 273: 1015-1022. [Abstract] [PDF]  

GC Palmer, ML Stagnitto, GE Garske, JJ Napier, EW Harris, FC Kaiser, RC Griffith, JH Woodhead, HS White, and HH Wolf

Anticonvulsant efficacy/safety properties of 2-amino-N-(1,2- diphenylethyl)acetamide hydrochloride
J Pharmacol Exp Ther 1995 273: 1023-1031. [Abstract] [PDF]  

A Gobert, F Lejeune, JM Rivet, V Audinot, A Newman-Tancredi, and MJ Millan

Modulation of the activity of central serotoninergic neurons by novel serotonin1A receptor agonists and antagonists: a comparison to adrenergic and dopaminergic neurons in rats
J Pharmacol Exp Ther 1995 273: 1032-1046. [Abstract] [PDF]  

LY Liu-Chen, HH Yang, S Li, and JU Adams

Effect of intracerebroventricular beta-funaltrexamine on mu opioid receptors in the rat brain: consideration of binding condition
J Pharmacol Exp Ther 1995 273: 1047-1056. [Abstract] [PDF]  

PJ Monroe, DL Smith, HR Kirk, and DJ Smith

Spinal nonadrenergic imidazoline receptors do not mediate the antinociceptive action of intrathecal clonidine in the rat
J Pharmacol Exp Ther 1995 273: 1057-1062. [Abstract] [PDF]  

BK Yamamoto, JF Nash, and GA Gudelsky

Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra
J Pharmacol Exp Ther 1995 273: 1063-1070. [Abstract] [PDF]  

M Feletou, P Robineau, M Lonchampt, E Bonnardel, C Thurieau, JL Fauchere, P Widdowson, JP Mahieu, B Serkiz, and JP Volland

S 16118 (p-guanidobenzoyl-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin) is a potent and long-acting bradykinin B2 receptor antagonist, in vitro and in vivo
J Pharmacol Exp Ther 1995 273: 1071-1077. [Abstract] [PDF]  

M Feletou, M Lonchampt, P Robineau, I Jamonneau, C Thurieau, JL Fauchere, P Villa, P Ghezzi, JF Prost, and E Canet

Effects of the bradykinin B2 receptor antagonist S 16118 (p- guanidobenzoyl-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin) in different in vivo animal models of inflammation
J Pharmacol Exp Ther 1995 273: 1078-1084. [Abstract] [PDF]  

LL Howell

Effects of caffeine on ventilation during acute and chronic nicotine administration in rhesus monkeys
J Pharmacol Exp Ther 1995 273: 1085-1094. [Abstract] [PDF]  

A Zaza, G Malfatto, and PJ Schwartz

Effects on atrial repolarization of the interaction between K+ channel blockers and muscarinic receptor stimulation
J Pharmacol Exp Ther 1995 273: 1095-1104. [Abstract] [PDF]  

NA Shahabi and BM Sharp

Antiproliferative effects of delta opioids on highly purified CD4+ and CD8+ murine T cells
J Pharmacol Exp Ther 1995 273: 1105-1113. [Abstract] [PDF]  

T Kuwabara, T Uchimura, K Takai, H Kobayashi, S Kobayashi, and Y Sugiyama

Saturable uptake of a recombinant human granulocyte colony-stimulating factor derivative, nartograstim, by the bone marrow and spleen of rats in vivo
J Pharmacol Exp Ther 1995 273: 1114-1122. [Abstract] [PDF]  

GW Gullikson, RF Loeffler, DV Mehrotra, JJ Casler, RG Bianchi, RE Schmidt, N Khoshaba, and WE Perkins

Polymeric delivery of the active isomer of misoprostol reduces systemic availability and uterotonic activity
J Pharmacol Exp Ther 1995 273: 1123-1131. [Abstract] [PDF]  

S Birnstiel and SG Beck

Modulation of the 5-hydroxytryptamine4 receptor-mediated response by short-term and long-term administration of corticosterone in rat CA1 hippocampal pyramidal neurons
J Pharmacol Exp Ther 1995 273: 1132-1138. [Abstract] [PDF]  

MS Brodie, RD Trifunovic, and SA Shefner

Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains
J Pharmacol Exp Ther 1995 273: 1139-1146. [Abstract] [PDF]  

MC Chabot-Fletcher, DC Underwood, JJ Breton, JL Adams, A Kagey-Sobotka, DE Griswold, LA Marshall, HM Sarau, JD Winkler, and DW Hay

Pharmacological characterization of SB 202235, a potent and selective 5- lipoxygenase inhibitor: effects in models of allergic asthma
J Pharmacol Exp Ther 1995 273: 1147-1155. [Abstract] [PDF]  

Z Jayyosi, D Knoble, M Muc, J Erick, PE Thomas, and M Kelley

Cytochrome P-450 2E1 is not the sole catalyst of chlorzoxazone hydroxylation in rat liver microsomes. off
J Pharmacol Exp Ther 1995 273: 1156-1161. [Abstract] [PDF]  

JJ Buccafusco, CA Lapp, KL Westbrooks, and P Ernsberger

Role of medullary I1-imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats
J Pharmacol Exp Ther 1995 273: 1162-1171. [Abstract] [PDF]  

IB Adams, W Ryan, M Singer, BF Thomas, DR Compton, RK Razdan, and BR Martin

Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs
J Pharmacol Exp Ther 1995 273: 1172-1181. [Abstract] [PDF]  

H Matsuda, K Miyatake, and SE Dahlen

Pharmacodynamics of 15(S)-hydroperoxyeicosatetraenoic (15-HPETE) and 15(S)-hydroxyeicosatetraenoic acid (15-HETE) in isolated arteries from guinea pig, rabbit, rat and human
J Pharmacol Exp Ther 1995 273: 1182-1189. [Abstract] [PDF]  

J Greven

Effects of cicletanine on kidney function. 1. Clearance and micropuncture studies in anesthetized rats
J Pharmacol Exp Ther 1995 273: 1190-1196. [Abstract] [PDF]  

J Greven, A Rahn, and E Brandle

Effects of cicletanine on kidney function. 2. Role of renal prostaglandins and kinins, and of muscarinic receptors
J Pharmacol Exp Ther 1995 273: 1197-1202. [Abstract] [PDF]  

GN Ervin, LS Birkemo, MF Johnson, LK Conger, JT Mosher, and JA Jr Menius

The effects of anorectic and aversive agents on deprivation-induced feeding and taste aversion conditioning in rats
J Pharmacol Exp Ther 1995 273: 1203-1210. [Abstract] [PDF]  

HY Wang, JM Yeung, and E Friedman

Prenatal cocaine exposure selectively reduces mesocortical dopamine release
J Pharmacol Exp Ther 1995 273: 1211-1215. [Abstract] [PDF]  

KL McCoy, D Gainey, and GA Cabral

delta 9-Tetrahydrocannabinol modulates antigen processing by macrophages
J Pharmacol Exp Ther 1995 273: 1216-1223. [Abstract] [PDF]  

LM Gracz and BK Madras

[3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum
J Pharmacol Exp Ther 1995 273: 1224-1234. [Abstract] [PDF]  

SP Welch, LD Dunlow, GS Patrick, and RK Razdan

Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception
J Pharmacol Exp Ther 1995 273: 1235-1244. [Abstract] [PDF]  

SS Negus, NK Mello, PS Portoghese, SE Lukas, and JH Mendelson

Role of delta opioid receptors in the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys
J Pharmacol Exp Ther 1995 273: 1245-1256. [Abstract] [PDF]  

H Tsukagoshi, EB Haddad, PJ Barnes, and KF Chung

Bradykinin receptor subtypes in rat lung: effect of interleukin-1 beta
J Pharmacol Exp Ther 1995 273: 1257-1263. [Abstract] [PDF]  

A Bril, JF Faivre, MC Forest, B Cheval, B Gout, P Linee, RR Jr Ruffolo, and RH Poyser

Electrophysiological effect of BRL-32872, a novel antiarrhythmic agent with potassium and calcium channel blocking properties, in guinea pig cardiac isolated preparations
J Pharmacol Exp Ther 1995 273: 1264-1272. [Abstract] [PDF]  

T Ogura, LM Shuba, and TF McDonald

Action potentials, ionic currents and cell water in guinea pig ventricular preparations exposed to dimethyl sulfoxide
J Pharmacol Exp Ther 1995 273: 1273-1286. [Abstract] [PDF]  

W Erdbrugger, M Raulf, T Otto, and MC Michel

Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2- adrenoceptor agonist high-affinity sites than [3H]rauwolscine? A comparison of nine tissues and cell lines
J Pharmacol Exp Ther 1995 273: 1287-1294. [Abstract] [PDF]  

WR Tracey, M Nakane, J Kuk, G Budzik, V Klinghofer, R Harris, and G Carter

The nitric oxide synthase inhibitor, L-NG-monomethylarginine, reduces carrageenan-induced pleurisy in the rat
J Pharmacol Exp Ther 1995 273: 1295-1299. [Abstract] [PDF]  

CA Snel, MM Moons, FG Russel, and GJ Mulder

Disposition of the bromosulfophthalein-glutathione conjugate in the isolated perfused rat kidney
J Pharmacol Exp Ther 1995 273: 1300-1306. [Abstract] [PDF]  

DM Thompson, J Auta, A Guidotti, and E Costa

Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys
J Pharmacol Exp Ther 1995 273: 1307-1312. [Abstract] [PDF]  

M Hosokawa, H Tsukada, S Ueda, M Sakai, M Okuma, K Oda, M Takimoto, T Okada, and Y Urade

Regulation of ion transport by endothelins in rat colonic mucosa: effects of an ETA antagonist (FR139317) and an ETB agonist (IRL1620)
J Pharmacol Exp Ther 1995 273: 1313-1322. [Abstract] [PDF]  

D Deleu, S Sarre, G Ebinger, and Y Michotte

The effect of carbidopa and entacapone pretreatment on the L-dopa pharmacokinetics and metabolism in blood plasma and skeletal muscle in beagle dog: an in vivo microdialysis study
J Pharmacol Exp Ther 1995 273: 1323-1331. [Abstract] [PDF]  

CY Ng, PW Angus, H Ghabrial, ST Chou, L Arnolda, DJ Morgan, and RA Smallwood

Right heart failure impairs hepatic oxygenation and theophylline clearance in rats
J Pharmacol Exp Ther 1995 273: 1332-1336. [Abstract] [PDF]  

H Koganei, T Kimura, and S Satoh

Effects of beta adrenoceptor agonists and antagonists on adrenal catecholamine release in response to splanchnic nerve stimulation in anesthetized dogs: role of beta-1 and beta-2 adrenoceptors
J Pharmacol Exp Ther 1995 273: 1337-1344. [Abstract] [PDF]  

EA Walker, G Zernig, and JH Woods

Buprenorphine antagonism of mu opioids in the rhesus monkey tail- withdrawal procedure
J Pharmacol Exp Ther 1995 273: 1345-1352. [Abstract] [PDF]  

RT Windh and CM Kuhn

Increased sensitivity to mu opiate antinociception in the neonatal rat despite weaker receptor-guanyl nucleotide binding protein coupling
J Pharmacol Exp Ther 1995 273: 1353-1360. [Abstract] [PDF]  

RT Windh, PJ Little, and CM Kuhn

The ontogeny of mu opiate tolerance and dependence in the rat: antinociceptive and biochemical studies
J Pharmacol Exp Ther 1995 273: 1361-1374. [Abstract] [PDF]  

JH Ludens, MA Clark, and JA Lawson

Effects of a K+ channel blocker on glomerular filtration rate and electrolyte excretion in conscious rats
J Pharmacol Exp Ther 1995 273: 1375-1381. [Abstract] [PDF]  

T Wang, WH Wang, G Klein-Robbenhaar, and G Giebisch

Effects of a novel KATP channel blocker on renal tubule function and K channel activity
J Pharmacol Exp Ther 1995 273: 1382-1389. [Abstract] [PDF]  

R Ishii, K Shinozuka, M Kunitomo, T Hashimoto, and K Takeuchi

Characterization of the facilitatory prejunctional purinoceptor on adrenergic nerves of the rabbit ear artery
J Pharmacol Exp Ther 1995 273: 1390-1395. [Abstract] [PDF]  

MS Barnette, M Grous, LB Cieslinski, M Burman, SB Christensen, and TJ Torphy

Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site
J Pharmacol Exp Ther 1995 273: 1396-1402. [Abstract] [PDF]  

S Takeo, K Tanonaka, M Hayashi, K Yamamoto, JX Liu, T Kamiyama, N Yamaguchi, A Miura, and T Natsukawa

A possible involvement of sodium channel blockade of class-I-type antiarrhythmic agents in postischemic contractile recovery of isolated, perfused hearts [published erratum appears in J Pharmacol Exp Ther 1995 Oct;275(1):527]
J Pharmacol Exp Ther 1995 273: 1403-1409. [Abstract] [PDF]  

EE Reynolds, JA Keiser, SJ Haleen, DM Walker, B Olszewski, RL Schroeder, DG Taylor, O Hwang, KM Welch, and MA Flynn

Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist
J Pharmacol Exp Ther 1995 273: 1410-1417. [Abstract] [PDF]  

MJ Millan, JM Rivet, V Audinot, A Gobert, F Lejeune, M Brocco, A Newman- Tancredi, S Maurel-Remy, and K Bervoets

Antagonist properties of LY 165,163 at pre- and postsynaptic dopamine D2, D3 and D1 receptors: modulation of agonist actions at 5-HT1A receptors in vivo
J Pharmacol Exp Ther 1995 273: 1418-1427. [Abstract] [PDF]  

GM Pitcher, K Yashpal, TJ Coderre, and JL Henry

mu-, delta- and kappa-opiate receptors mediate antinociception in the rat tail flick test following noxious thermal stimulation of one hindpaw
J Pharmacol Exp Ther 1995 273: 1428-1433. [Abstract] [PDF]  

DJ Anderson, M Williams, JR Pauly, JL Raszkiewicz, JE Campbell, G Rotert, B Surber, SB Thomas, J Wasicak, and SP Arneric

Characterization of [3H]ABT-418: a novel cholinergic channel ligand
J Pharmacol Exp Ther 1995 273: 1434-1441. [Abstract] [PDF]  

TL Yue, X Wang, JL Gu, RR Jr Ruffolo, and GZ Feuerstein

Carvedilol, a new vasodilating beta-adrenoceptor blocker, inhibits oxidation of low-density lipoproteins by vascular smooth muscle cells and prevents leukocyte adhesion to smooth muscle cells
J Pharmacol Exp Ther 1995 273: 1442-1449. [Abstract] [PDF]  

C Betancur, M Canton, D Gully, G Vela, D Pelaprat, and W Rostene

Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain
J Pharmacol Exp Ther 1995 273: 1450-1458. [Abstract] [PDF]  

K Ishihara, M Alkondon, JG Montes, and EX Albuquerque

Ontogenically related properties of N-methyl-D-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead
J Pharmacol Exp Ther 1995 273: 1459-1470. [Abstract] [PDF]  

K Ishihara, M Alkondon, JG Montes, and EX Albuquerque

Nicotinic responses in acutely dissociated rat hippocampal neurons and the selective blockade of fast-desensitizing nicotinic currents by lead
J Pharmacol Exp Ther 1995 273: 1471-1482. [Abstract] [PDF]  

KE Asin, L Bednarz, A Nikkel, and R Perner

Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa
J Pharmacol Exp Ther 1995 273: 1483-1490. [Abstract] [PDF]  

SM Belkowski, C Alicea, TK Eisenstein, MW Adler, and TJ Rogers

Inhibition of interleukin-1 and tumor necrosis factor-alpha synthesis following treatment of macrophages with the kappa opioid agonist U50, 488H
J Pharmacol Exp Ther 1995 273: 1491-1496. [Abstract] [PDF]  

Y Dai and AI Cederbaum

Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells
J Pharmacol Exp Ther 1995 273: 1497-1505. [Abstract] [PDF]  

M Bradshaw, MS Rutherford, BJ Hoeper, CD McWhinney, DR Borcherding, LB Schook, and CK 3rd. Edwards

Specific transcriptional inhibition of bone marrow-derived macrophage tumor necrosis factor-alpha gene expression and protein production using novel enantiomeric carbocyclic nucleoside analogues
J Pharmacol Exp Ther 1995 273: 1506-1518. [Abstract] [PDF]  

S Chandrasekhar, AK Harvey, CP Dell, SJ Ambler, and CW Smith

Identification of a novel chemical series that blocks interleukin-1- stimulated metalloprotease activity in chondrocytes
J Pharmacol Exp Ther 1995 273: 1519-1528. [Abstract] [PDF]  

M Katsura, S Ohkuma, A Tsujimura, and K Kuriyama

Increase of diazepam binding inhibitor mRNA levels in the brains of chronically ethanol-treated and -withdrawn mice
J Pharmacol Exp Ther 1995 273: 1529-1533. [Abstract] [PDF]  

PK Banerjee and OC 3rd Snead

Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GHB
J Pharmacol Exp Ther 1995 273: 1534-1543. [Abstract] [PDF]  

G Thomas, K Ito, E Zikic, T Bhatti, C Han, and PW Ramwell

Specific inhibition of the contraction of the rat aorta by estradiol 17 beta
J Pharmacol Exp Ther 1995 273: 1544-1550. [Abstract] [PDF]  

JM Little, RR Drake, R Vonk, F Kuipers, R Lester, and A Radominska

Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs
J Pharmacol Exp Ther 1995 273: 1551-1559. [Abstract] [PDF]  

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