ARTICLES:

JA Keiser, MJ Ryan, RL Panek, JC Hodges, and I Sircar

Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist
J Pharmacol Exp Ther 1995 272: 963-969. [Abstract] [PDF]  

DB Joseph and JM Bidlack

The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure
J Pharmacol Exp Ther 1995 272: 970-976. [Abstract] [PDF]  

P Ronde, H Ansanay, A Dumuis, R Miller, and J Bockaert

Homologous desensitization of 5-hydroxytryptamine4 receptors in rat esophagus: functional and second messenger studies
J Pharmacol Exp Ther 1995 272: 977-983. [Abstract] [PDF]  

M Pirmohamed, D Williams, S Madden, E Templeton, and BK Park

Metabolism and bioactivation of clozapine by human liver in vitro
J Pharmacol Exp Ther 1995 272: 984-990. [Abstract] [PDF]  

HA el-Fawal and RW Wood

Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine
J Pharmacol Exp Ther 1995 272: 991-996. [Abstract] [PDF]  

JL Ellis and ND Conanan

Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea
J Pharmacol Exp Ther 1995 272: 997-1004. [Abstract] [PDF]  

RS Sheldon and E Thakore

Ring and link requirements for tocainide binding to the class I antiarrhythmic drug receptor on rat cardiac myocytes
J Pharmacol Exp Ther 1995 272: 1005-1010. [Abstract] [PDF]  

WR Tracey, J Tse, and G Carter

Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors
J Pharmacol Exp Ther 1995 272: 1011-1015. [Abstract] [PDF]  

MF Hare and WD Atchison

Methylmercury mobilizes Ca++ from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells
J Pharmacol Exp Ther 1995 272: 1016-1023. [Abstract] [PDF]  

DM Dennis, JC Shryock, and L Belardinelli

Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node
J Pharmacol Exp Ther 1995 272: 1024-1035. [Abstract] [PDF]  

C Scavone, C Scanlon, M McKee, and JA Nathanson

Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase
J Pharmacol Exp Ther 1995 272: 1036-1043. [Abstract] [PDF]  

M Matsumoto, M Yoshioka, H Togashi, M Tochihara, T Ikeda, and H Saito

Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis
J Pharmacol Exp Ther 1995 272: 1044-1051. [Abstract] [PDF]  

DE Semler, EH Ohlstein, P Nambi, C Slater, and PH Stern

Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors
J Pharmacol Exp Ther 1995 272: 1052-1058. [Abstract] [PDF]  

NK Mello, Z Sarnyai, JH Mendelson, JM Drieze, and M Kelly

The acute effects of cocaine on anterior pituitary hormones in ovariectomized rhesus monkeys
J Pharmacol Exp Ther 1995 272: 1059-1066. [Abstract] [PDF]  

A Katoh, M Eigyo, C Ishibashi, Y Naitoh, M Takeuchi, N Ibii, M Ikeda, and A Matsushita

Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats
J Pharmacol Exp Ther 1995 272: 1067-1075. [Abstract] [PDF]  

JO Miners, DL Rees, L Valente, ME Veronese, and DJ Birkett

Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism
J Pharmacol Exp Ther 1995 272: 1076-1081. [Abstract] [PDF]  

R Patacchini, L Quartara, M Astolfi, C Goso, A Giachetti, and CA Maggi

Activity of cyclic pseudopeptide antagonists at peripheral tachykinin receptors
J Pharmacol Exp Ther 1995 272: 1082-1087. [Abstract] [PDF]  

H Zhong and KP Minneman

Coexisting beta-1 and beta-2-adrenergic receptors with differential receptor reserves in rat C6 glioma cells
J Pharmacol Exp Ther 1995 272: 1088-1094. [Abstract] [PDF]  

S Takahashi, Y Kato, M Adachi, N Agata, H Tanaka, and K Shigenobu

Effects of cyclopiazonic acid on rat myocardium: inhibition of calcium uptake into sarcoplasmic reticulum
J Pharmacol Exp Ther 1995 272: 1095-1100. [Abstract] [PDF]  

K Igarashi and K Williams

Antagonist properties of polyamines and bis(ethyl)polyamines at N- methyl-D-aspartate receptors
J Pharmacol Exp Ther 1995 272: 1101-1109. [Abstract] [PDF]  

A Parent, W Rowe, MJ Meaney, and R Quirion

Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic- glutamate and endothelin receptors
J Pharmacol Exp Ther 1995 272: 1110-1116. [Abstract] [PDF]  

DE Keyler, DG Le Couteur, SM Pond, JV St Peter, and PR Pentel

Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver
J Pharmacol Exp Ther 1995 272: 1117-1123. [Abstract] [PDF]  

ML Webb, JE Bird, EC Liu, PM Rose, R Serafino, PD Stein, and S Moreland

BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist
J Pharmacol Exp Ther 1995 272: 1124-1134. [Abstract] [PDF]  

TJ Martin, SI Dworkin, and JE Smith

Alkylation of mu opioid receptors by beta-funaltrexamine in vivo: comparison of the effects on in situ binding and heroin self- administration in rats
J Pharmacol Exp Ther 1995 272: 1135-1140. [Abstract] [PDF]  

JS Fedan, TE Warner, LX Yuan, Va Robinson, and DG Frazer

Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways
J Pharmacol Exp Ther 1995 272: 1141-1150. [Abstract] [PDF]  

S Takayanagi, H Hanai, J Kumagai, and E Kaneko

Serotonin uptake and its modulation in rat jejunal enterocyte preparation
J Pharmacol Exp Ther 1995 272: 1151-1159. [Abstract] [PDF]  

AA Hancock, SA Buckner, WJ Giardina, ME Brune, JY Lee, PA Morse, KW Oheim, DS Stanisic, RB Warner, and DJ Kerkman

Preclinical pharmacological actions of (+/-)-(1'R*,3R*)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine
J Pharmacol Exp Ther 1995 272: 1160-1169. [Abstract] [PDF]  

S Nishino, J Shelton, A Renaud, WC Dement, and E Mignot

Effect of 5-HT1A receptor agonists and antagonists on canine cataplexy
J Pharmacol Exp Ther 1995 272: 1170-1175. [Abstract] [PDF]  

BA Bennett, CH Wichems, CK Hollingsworth, HM Davies, C Thornley, T Sexton, and SR Childers

Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain
J Pharmacol Exp Ther 1995 272: 1176-1186. [Abstract] [PDF]  

JW Van Huysse, DP Henry, and LR Willis

In vivo renal production and tubular secretion of tyramine
J Pharmacol Exp Ther 1995 272: 1187-1192. [Abstract] [PDF]  

K Shinozuka, M Kunitomo, K Hattori, RA Bjur, and DP Westfall

Differences in purinoceptor modulation of norepinephrine release between caudal arteries of normotensive and hypertensive rats
J Pharmacol Exp Ther 1995 272: 1193-1198. [Abstract] [PDF]  

DW Bonhaus, KR Bley, CA Broka, DJ Fontana, E Leung, R Lewis, A Shieh, and EH Wong

Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine
J Pharmacol Exp Ther 1995 272: 1199-1203. [Abstract] [PDF]  

PL Smith, CP Lee, M Pullen, EH Ohlstein, G Beck, EP Eddy, and P Nambi

Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects
J Pharmacol Exp Ther 1995 272: 1204-1210. [Abstract] [PDF]  

S Rattan, GJ Rosenthal, and S Chakder

Human recombinant hemoglobin (rHb1.1) inhibits nonadrenergic noncholinergic (NANC) nerve-mediated relaxation of internal anal sphincter
J Pharmacol Exp Ther 1995 272: 1211-1216. [Abstract] [PDF]  

K Van Belle, S Sarre, G Ebinger, and Y Michotte

Brain, liver and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study
J Pharmacol Exp Ther 1995 272: 1217-1222. [Abstract] [PDF]  

M Kahonen, H Makynen, P Arvola, H Wuorela, and I Porsti

Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats
J Pharmacol Exp Ther 1995 272: 1223-1230. [Abstract] [PDF]  

SA Azer, V Kukongviriyapan, and NH Stacey

Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes
J Pharmacol Exp Ther 1995 272: 1231-1237. [Abstract] [PDF]  

G Bannenberg, J Xue, L Engman, I Cotgreave, P Moldeus, and A Ryrfeldt

Characterization of bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung
J Pharmacol Exp Ther 1995 272: 1238-1245. [Abstract] [PDF]  

LR Flores, SM Wahl, and BM Bayer

Mechanisms of morphine-induced immunosuppression: effect of acute morphine administration on lymphocyte trafficking
J Pharmacol Exp Ther 1995 272: 1246-1251. [Abstract] [PDF]  

M Sato, J Kim, LL Short, CW Slemenda, and HU Bryant

Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats
J Pharmacol Exp Ther 1995 272: 1252-1259. [Abstract] [PDF]  

I Mitrovic and TC Napier

Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum
J Pharmacol Exp Ther 1995 272: 1260-1270. [Abstract] [PDF]  

O Pol, E Planas, and MM Puig

Peripheral effects of naloxone in mice with acute diarrhea associated with intestinal inflammation
J Pharmacol Exp Ther 1995 272: 1271-1276. [Abstract] [PDF]  

EM Mokrzan, LE Kerper, N Ballatori, and TW Clarkson

Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L
J Pharmacol Exp Ther 1995 272: 1277-1284. [Abstract] [PDF]  

I Khan, N Lapierre, and PK Rangachari

Messenger RNAs for neurokinin and histamine receptor subtypes in isolated canine colonic crypts
J Pharmacol Exp Ther 1995 272: 1285-1292. [Abstract] [PDF]  

SE Shehin-Johnson, DE Williams, S Larsen-Su, DM Stresser, and RN Hines

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit
J Pharmacol Exp Ther 1995 272: 1293-1299. [Abstract] [PDF]  

K Kaechi, R Ikegami, N Nakamura, M Nakajima, Y Furukawa, and S Furukawa

4-Methylcatechol, an inducer of nerve growth factor synthesis, enhances peripheral nerve regeneration across nerve gaps
J Pharmacol Exp Ther 1995 272: 1300-1304. [Abstract] [PDF]  

X Tao, JJ Cai, and PE Lipsky

The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook. F
J Pharmacol Exp Ther 1995 272: 1305-1312. [Abstract] [PDF]  

MW Verghese, RT McConnell, AB Strickland, RC Gooding, SA Stimpson, DP Yarnall, JD Taylor, and PJ Furdon

Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors
J Pharmacol Exp Ther 1995 272: 1313-1320. [Abstract] [PDF]  

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