ARTICLES:

K Fecho, KA Maslonek, LA Dykstra, and DT Lysle

Mechanisms whereby macrophage-derived nitric oxide is involved in morphine-induced suppression of splenic lymphocyte proliferation
J Pharmacol Exp Ther 1995 272: 477-483. [Abstract] [PDF]  

I Grattagliano, P Wieland, C Schranz, and BH Lauterburg

Disposition of glutathione monoethyl ester in the rat: glutathione ester is a slow release form of extracellular glutathione
J Pharmacol Exp Ther 1995 272: 484-488. [Abstract] [PDF]  

D Mullikin-Kilpatrick and SN Treistman

Inhibition of dihydropyridine-sensitive Ca++ channels by ethanol in undifferentiated and nerve growth factor-treated PC12 cells: interaction with the inactivated state
J Pharmacol Exp Ther 1995 272: 489-497. [Abstract] [PDF]  

ML Veyries, M Sinet, B Desforges, and B Rouveix

Effects of morphine on the pathogenesis of murine Friend retrovirus infection
J Pharmacol Exp Ther 1995 272: 498-504. [Abstract] [PDF]  

M Ohtani, H Kotaki, Y Sawada, and T Iga

Comparative analysis of buprenorphine- and norbuprenorphine-induced analgesic effects based on pharmacokinetic-pharmacodynamic modeling
J Pharmacol Exp Ther 1995 272: 505-510. [Abstract] [PDF]  

DR Luthin and J Linden

Comparison of A4 and A2a binding sites in striatum and COS cells transfected with adenosine A2a receptors
J Pharmacol Exp Ther 1995 272: 511-518. [Abstract] [PDF]  

S Apparsundaram and DC Eikenburg

Role of prejunctional beta adrenoceptors in rat cardiac sympathetic neurotransmission
J Pharmacol Exp Ther 1995 272: 519-526. [Abstract] [PDF]  

L Garofalo and AC Cuello

Pharmacological characterization of nerve growth factor and/or monosialoganglioside GM1 effects on cholinergic markers in the adult lesioned brain
J Pharmacol Exp Ther 1995 272: 527-545. [Abstract] [PDF]  

A Ohnishi, Y Orita, N Takagi, T Fujita, T Toyoki, Y Ihara, Y Yamamura, T Inoue, and T Tanaka

Aquaretic effect of a potent, orally active, nonpeptide V2 antagonist in men [published erratum appears in J Pharmacol Exp Ther 1995 Sep;274(3):1573]
J Pharmacol Exp Ther 1995 272: 546-551. [Abstract] [PDF]  

ED Pakarinen, JH Woods, and JM Moerschbaecher

Repeated acquisition of behavioral chains in squirrel monkeys: comparisons of a mu, kappa and delta opioid agonist
J Pharmacol Exp Ther 1995 272: 552-559. [Abstract] [PDF]  

JL Azorlosa, MK Greenwald, and ML Stitzer

Marijuana smoking: effects of varying puff volume and breathhold duration
J Pharmacol Exp Ther 1995 272: 560-569. [Abstract] [PDF]  

GK Mumford, CR Rush, and RR Griffiths

Abecarnil and alprazolam in humans: behavioral, subjective and reinforcing effects
J Pharmacol Exp Ther 1995 272: 570-580. [Abstract] [PDF]  

JE Piletz, DN Chikkala, and P Ernsberger

Comparison of the properties of agmatine and endogenous clonidine- displacing substance at imidazoline and alpha-2 adrenergic receptors
J Pharmacol Exp Ther 1995 272: 581-587. [Abstract] [PDF]  

G Luo and TM Guenthner

Metabolism of allylbenzene 2',3'-oxide and estragole 2',3'-oxide in the isolated perfused rat liver
J Pharmacol Exp Ther 1995 272: 588-596. [Abstract] [PDF]  

GH Dillon, WB Im, JF Pregenzer, DB Carter, and BJ Hamilton

[4-Dimethyl-3-t-butylcarboxyl-4,5-dihydro (1,5-a) quinoxaline] is a novel ligand to the picrotoxin site on GABAA receptors, and decreases single-channel open probability
J Pharmacol Exp Ther 1995 272: 597-603. [Abstract] [PDF]  

ZM Quezado, C Natanson, SM Banks, DW Alling, CA Koev, RL Danner, RJ Elin, JM Hosseini, TS Parker, and DM Levine

Therapeutic trial of reconstituted human high-density lipoprotein in a canine model of gram-negative septic shock
J Pharmacol Exp Ther 1995 272: 604-611. [Abstract] [PDF]  

HT Beauchamp, RS Chang, PK Siegl, and RE Gibson

In vivo receptor occupancy of the angiotensin II receptor by nonpeptide antagonists: relationship to in vitro affinities and in vivo pharmacologic potency
J Pharmacol Exp Ther 1995 272: 612-618. [Abstract] [PDF]  

NC Trippodo, BC Panchal, and M Fox

Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure
J Pharmacol Exp Ther 1995 272: 619-627. [Abstract] [PDF]  

EC Strain, KL Preston, IA Liebson, and GE Bigelow

Buprenorphine effects in methadone-maintained volunteers: effects at two hours after methadone
J Pharmacol Exp Ther 1995 272: 628-638. [Abstract] [PDF]  

M Murray and AM Butler

Identification of a reversible component in the in vitro inhibition of rat hepatic cytochrome P450 2B1 by parathion
J Pharmacol Exp Ther 1995 272: 639-644. [Abstract] [PDF]  

JM Spitsbergen and WD Atchison

The paralytic agent 2,4-dithiobiuret decreases open time of murine skeletal muscle acetylcholine receptor channels
J Pharmacol Exp Ther 1995 272: 645-651. [Abstract] [PDF]  

IM Maisonneuve, A Ho, and MJ Kreek

Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: an in vivo microdialysis study
J Pharmacol Exp Ther 1995 272: 652-657. [Abstract] [PDF]  

JV Garaulet, MV Milanes, and ML Laorden

Cross-tolerance between kappa and mu opioid agonists in the guinea pig ileum myenteric plexus
J Pharmacol Exp Ther 1995 272: 658-662. [Abstract] [PDF]  

WH Dantzler, KK Evans, and SH Wright

Kinetics of interactions of para-aminohippurate, probenecid, cysteine conjugates and N-acetyl cysteine conjugates with basolateral organic anion transporter in isolated rabbit proximal renal tubules
J Pharmacol Exp Ther 1995 272: 663-672. [Abstract] [PDF]  

Y Dumont, A Fournier, S St-Pierre, and R Quirion

Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [125I][Leu31,Pro34]peptide YY and [125I]peptide YY3- 36 as selective Y1 and Y2 radioligands
J Pharmacol Exp Ther 1995 272: 673-680. [Abstract] [PDF]  

C Carpene, P Collon, A Remaury, A Cordi, A Hudson, D Nutt, and M Lafontan

Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites
J Pharmacol Exp Ther 1995 272: 681-688. [Abstract] [PDF]  

CR Albrightson, PJ Bugelski, TA Berkhout, B Jackson, WD Kerns, AJ Organ, and AM Badger

Separation of immunomodulatory and cholesterol-lowering activities of heterocyclic azaspiranes
J Pharmacol Exp Ther 1995 272: 689-698. [Abstract] [PDF]  

E Fride, J Barg, R Levy, D Saya, E Heldman, R Mechoulam, and Z Vogel

Low doses of anandamides inhibit pharmacological effects of delta 9- tetrahydrocannabinol
J Pharmacol Exp Ther 1995 272: 699-707. [Abstract] [PDF]  

DJ Sanger and G Perrault

Effects of typical and atypical antipsychotic drugs on response decrement patterns in rats
J Pharmacol Exp Ther 1995 272: 708-713. [Abstract] [PDF]  

FG de Lorenzi, TR Bridal, and W Spinelli

Voltage-dependent inhibition of the ATP-sensitive K+ current by the class Ia agent disopyramide in cat ventricular myocytes
J Pharmacol Exp Ther 1995 272: 714-723. [Abstract] [PDF]  

RL Bell, JB Bouska, PE Malo, C Lanni, RR Harris, ER Otis, AO Stewart, DW Brooks, and GW Carter

Optimization of the potency and duration of action of N-hydroxyurea 5- lipoxygenase inhibitors
J Pharmacol Exp Ther 1995 272: 724-731. [Abstract] [PDF]  

HA Campos and J Dominguez

Interaction between noradrenergic and histamine-containing neurons in the rat vas deferens
J Pharmacol Exp Ther 1995 272: 732-738. [Abstract] [PDF]  

M Tomita, M Hayashi, and S Awazu

Absorption-enhancing mechanism of sodium caprate and decanoylcarnitine in Caco-2 cells
J Pharmacol Exp Ther 1995 272: 739-743. [Abstract] [PDF]  

Y Furukawa, H Nakano, T Oguchi, M Kasama, Y Hoyano, and S Chiba

Selective inhibition by zatebradine and discrete parasympathetic stimulation of the positive chronotropic response to sympathetic stimulation in anesthetized dogs
J Pharmacol Exp Ther 1995 272: 744-749. [Abstract] [PDF]  

A Hilditch, AA Hunt, A Travers, J Polley, GM Drew, D Middlemiss, DB Judd, BC Ross, and MJ Robertson

Pharmacological effects of GR138950, a novel angiotensin AT1 receptor antagonist
J Pharmacol Exp Ther 1995 272: 750-757. [Abstract] [PDF]  

DF Woodward, AL Nieves, CS Spada, LS Williams, and RP Tuckett

Characterization of a behavioral model for peripherally evoked itch suggests platelet-activating factor as a potent pruritogen
J Pharmacol Exp Ther 1995 272: 758-765. [Abstract] [PDF]  

SM Russo, JA Pepe, S Donohue, EE Cable, RW Lambrecht, and HL Bonkovsky

Tissue distribution of zinc-mesoporphyrin in rats: relationship to inhibition of heme oxygenase
J Pharmacol Exp Ther 1995 272: 766-774. [Abstract] [PDF]  

A Madan and MD Faiman

Characterization of diethyldithiocarbamate methyl ester sulfine as an intermediate in the bioactivation of disulfiram
J Pharmacol Exp Ther 1995 272: 775-780. [Abstract] [PDF]  

M Diana, M Pistis, A Muntoni, and G Gessa

Profound decrease of mesolimbic dopaminergic neuronal activity in morphine withdrawn rats
J Pharmacol Exp Ther 1995 272: 781-785. [Abstract] [PDF]  

IG Johansson-Rydberg, N Grundstrom, and RG Andersson

Pertussis toxin attenuates presynaptic inhibition of cholinergic but not nonadrenergic noncholinergic contraction in guinea pig airways
J Pharmacol Exp Ther 1995 272: 786-790. [Abstract] [PDF]  

CW Schindler, SR Tella, J Prada, and SR Goldberg

Calcium channel blockers antagonize some of cocaine's cardiovascular effects, but fail to alter cocaine's behavioral effects
J Pharmacol Exp Ther 1995 272: 791-798. [Abstract] [PDF]  

GP Dube, JA Jakubowski, KA Brune, KG Bemis, and WL Kurtz

In vivo effects of a novel thromboxane A2/prostaglandin H2 (TXA2/PGH2) partial agonist, (+)5(Z)-7-[3-endo-phenylsulfonylamino[2.2.1]- bicyclohept-2-exo-yl]-heptenoic acid [(+)-S-145], on vascular, platelet and cardiac function
J Pharmacol Exp Ther 1995 272: 799-807. [Abstract] [PDF]  

M Watanabe, Y Kawase, J Tanabe, KR Min, S Mue, and K Ohuchi

Suppression of interleukin-1 alpha production by protein kinase C activators in human vascular endothelial cells
J Pharmacol Exp Ther 1995 272: 808-814. [Abstract] [PDF]  

J Raber, GF Koob, and FE Bloom

Interleukin-2 (IL-2) induces corticotropin-releasing factor (CRF) release from the amygdala and involves a nitric oxide-mediated signaling; comparison with the hypothalamic response
J Pharmacol Exp Ther 1995 272: 815-824. [Abstract] [PDF]  

T Saeki, H Adachi, Y Takase, S Yoshitake, S Souda, and I Saito

A selective type V phosphodiesterase inhibitor, E4021, dilates porcine large coronary artery
J Pharmacol Exp Ther 1995 272: 825-831. [Abstract] [PDF]  

AJ Farre, M Colombo, I Alvarez, and GB Glavin

Some novel 5-hydroxytryptamine1A (5-HT1A) receptor agonists reduce gastric acid and pepsin secretion, reduce experimental gastric mucosal injury and enhance gastric mucus in rats
J Pharmacol Exp Ther 1995 272: 832-837. [Abstract] [PDF]  

T Oguchi, Y Furukawa, S Sawaki, M Kasama, and S Chiba

Are negative chronotropic and inotropic responses to adenosine differentiated at the receptor or postreceptor levels in isolated dog hearts?
J Pharmacol Exp Ther 1995 272: 838-844. [Abstract] [PDF]  

ER Butelman, G Winger, G Zernig, and JH Woods

Butorphanol: characterization of agonist and antagonist effects in rhesus monkeys
J Pharmacol Exp Ther 1995 272: 845-853. [Abstract] [PDF]  

PJ Blanchet, F Calon, JC Martel, PJ Bedard, T Di Paolo, RR Walters, and MF Piercey

Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U- 91356A) in MPTP-exposed monkeys
J Pharmacol Exp Ther 1995 272: 854-859. [Abstract] [PDF]  

GM Farfel and LS Seiden

Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX
J Pharmacol Exp Ther 1995 272: 860-867. [Abstract] [PDF]  

GM Farfel and LS Seiden

Role of hypothermia in the mechanism of protection against serotonergic toxicity. II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan
J Pharmacol Exp Ther 1995 272: 868-875. [Abstract] [PDF]  

WP Watson and HJ Little

Identification of distinct components, with different time courses, of the changes in response to convulsive stimuli during ethanol withdrawal
J Pharmacol Exp Ther 1995 272: 876-884. [Abstract] [PDF]  

B Desta, M Nakashima, M Kirchengast, PM Vanhoutte, and CM Boulanger

Previous exposure to bradykinin unmasks an endothelium-dependent relaxation to the converting enzyme inhibitor trandolaprilat in isolated canine coronary arteries
J Pharmacol Exp Ther 1995 272: 885-891. [Abstract] [PDF]  

F Orzi, Y Sun, K Pettigrew, L Sokoloff, and CB Smith

Effects of acute and delayed effects of prior chronic cocaine administration on regional rates of cerebral protein synthesis in rats
J Pharmacol Exp Ther 1995 272: 892-900. [Abstract] [PDF]  

LJ Porrino, HM Davies, and SR Childers

Behavioral and local cerebral metabolic effects of the novel tropane analog, 2 beta-propanoyl-3 beta-(4-tolyl)-tropane
J Pharmacol Exp Ther 1995 272: 901-910. [Abstract] [PDF]  

H Shinyama, H Nagai, T Kawamura, Y Narita, T Uchida, M Watanabe, and Y Kagitani

Protective effects of AE0047, a novel calcium antagonist, on incidence of stroke and hemodynamic disturbances in stroke-prone spontaneously hypertensive rats
J Pharmacol Exp Ther 1995 272: 911-919. [Abstract] [PDF]  

T Jolas, R Schreiber, AM Laporte, M Chastanet, J De Vry, T Glaser, J Adrien, and M Hamon

Are postsynaptic 5-HT1A receptors involved in the anxiolytic effects of 5-HT1A receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat?
J Pharmacol Exp Ther 1995 272: 920-929. [Abstract] [PDF]  

R Botla, JR Spivey, H Aguilar, SF Bronk, and GJ Gores

Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection
J Pharmacol Exp Ther 1995 272: 930-938. [Abstract] [PDF]  

T Hiroi, N Ohishi, S Imaoka, Y Yabusaki, H Fukui, and Y Funae

Mepyramine, a histamine H1 receptor antagonist, inhibits the metabolic activity of rat and human P450 2D forms
J Pharmacol Exp Ther 1995 272: 939-944. [Abstract] [PDF]  

MS Finkel, CV Oddis, OH Mayer, BG Hattler, and RL Simmons

Nitric oxide synthase inhibitor alters papillary muscle force-frequency relationship
J Pharmacol Exp Ther 1995 272: 945-952. [Abstract] [PDF]  

MJ Potchoiba, TG Tensfeldt, MR Nocerini, and BM Silber

A novel quantitative method for determining the biodistribution of radiolabeled xenobiotics using whole-body cryosectioning and autoradioluminography
J Pharmacol Exp Ther 1995 272: 953-962. [Abstract] [PDF]  

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