ARTICLES:

F Noble, C Smadja, and BP Roques

Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists
J Pharmacol Exp Ther 1994 271: 1127-1134. [Abstract] [PDF]  

Z Li, V Barrios, JN Buchholz, TC Glenn, and SP Duckles

Chronic nicotine administration does not affect peripheral vascular reactivity in the rat
J Pharmacol Exp Ther 1994 271: 1135-1142. [Abstract] [PDF]  

PJ Silver, RL Dundore, DC Bode, L de Garavilla, RA Buchholz, G van Aller, LT Hamel, E Bacon, B Singh, and GY Lesher

Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor
J Pharmacol Exp Ther 1994 271: 1143-1149. [Abstract] [PDF]  

AA Abdel-Rahman

Acute effects of ethanol on cardiac output and its derivatives in spontaneously hypertensive and normotensive rats
J Pharmacol Exp Ther 1994 271: 1150-1158. [Abstract] [PDF]  

DW Wilde

Isoflurane reduces Ca++ channel current and accelerates current decay in guinea pig portal vein smooth muscle cells
J Pharmacol Exp Ther 1994 271: 1159-1166. [Abstract] [PDF]  

G Dent, MA Giembycz, PM Evans, KF Rabe, and PJ Barnes

Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol
J Pharmacol Exp Ther 1994 271: 1167-1174. [Abstract] [PDF]  

AM Lin, RK Freund, BJ Hoffer, and MR Palmer

Ethanol-induced depressions of cerebellar Purkinje neurons are potentiated by beta-adrenergic mechanisms in rat brain
J Pharmacol Exp Ther 1994 271: 1175-1180. [Abstract] [PDF]  

ML Pucak and AA Grace

Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors
J Pharmacol Exp Ther 1994 271: 1181-1192. [Abstract] [PDF]  

U Schroder, H Schroder, W Augustin, and BA Sabel

Haloperidol-induced behavioral supersensitivity is increased by monosialoganglioside treatment in rats without affecting spiroperidol- binding
J Pharmacol Exp Ther 1994 271: 1193-1196. [Abstract] [PDF]  

JH Lin, IW Chen, and TH Lin

Blood-brain barrier permeability and in vivo activity of partial agonists of benzodiazepine receptor: a study of L-663,581 and its metabolites in rats
J Pharmacol Exp Ther 1994 271: 1197-1202. [Abstract] [PDF]  

MS Chintala, V Bernardino, and PJ Chiu

Cyclic GMP but not cyclic AMP prevents renal platelet accumulation after ischemia-reperfusion in anesthetized rats
J Pharmacol Exp Ther 1994 271: 1203-1208. [Abstract] [PDF]  

N Lepretre, S Arnaudeau, J Mironneau, L Rakotoarisoa, C Mironneau, and A Galiano

Electrophysiological and radioligand binding studies of elgodipine and derivatives in portal vein myocytes
J Pharmacol Exp Ther 1994 271: 1209-1215. [Abstract] [PDF]  

MH Baumann, GU Char, BR De Costa, KC Rice, and RB Rothman

GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat
J Pharmacol Exp Ther 1994 271: 1216-1222. [Abstract] [PDF]  

SS Shetty and D DelGrande

Inhibition by nickel of endothelin-1-induced tension and associated 45Ca movements in rabbit aorta
J Pharmacol Exp Ther 1994 271: 1223-1227. [Abstract] [PDF]  

AS Goetz, MW Lutz, TJ Rimele, and DL Jr Saussy

Characterization of alpha-1 adrenoceptor subtypes in human and canine prostate membranes
J Pharmacol Exp Ther 1994 271: 1228-1233. [Abstract] [PDF]  

SE Robinson, EK Enters, GF Jackson, VM Chinchilli, JR Maher, KP McDowell, HM Allen, and H Guo

Maternal and fetal brain and plasma levels of cocaine and benzoylecgonine after acute or chronic maternal intravenous administration of cocaine
J Pharmacol Exp Ther 1994 271: 1234-1239. [Abstract] [PDF]  

TH Chen and WH Hsu

Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP
J Pharmacol Exp Ther 1994 271: 1240-1245. [Abstract] [PDF]  

E Meller and K Bohmaker

Differential receptor reserve for 5-HT1A receptor-mediated regulation of plasma neuroendocrine hormones
J Pharmacol Exp Ther 1994 271: 1246-1252. [Abstract] [PDF]  

A Chaudhry and JG Granneman

Influence of cell type upon the desensitization of the beta 3- adrenergic receptor
J Pharmacol Exp Ther 1994 271: 1253-1258. [Abstract] [PDF]  

M Imamura, E Poli, AT Omoniyi, and R Levi

Unmasking of activated histamine H3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release
J Pharmacol Exp Ther 1994 271: 1259-1266. [Abstract] [PDF]  

S Yanai, H Okada, M Misaki, K Saito, Y Kuge, Y Ogawa, and H Toguchi

Antitumor activity of a medium-chain triglyceride solution of the angiogenesis inhibitor TNP-470 (AGM-1470) when administered via the hepatic artery to rats bearing Walker 256 carcinosarcoma in the liver
J Pharmacol Exp Ther 1994 271: 1267-1273. [Abstract] [PDF]  

DJ Pillion, JA Atchison, RX Wang, and E Meezan

Alkylglycosides enhance systemic absorption of insulin applied topically to the rat eye
J Pharmacol Exp Ther 1994 271: 1274-1280. [Abstract] [PDF]  

JS Kreeger, KF Kitto, and AA Larson

Substance P N-terminal metabolites and nitric oxide mediate capsaicin- induced antinociception in the adult mouse
J Pharmacol Exp Ther 1994 271: 1281-1285. [Abstract] [PDF]  

MS Dordal, M Jackson-Stone, AC Ho, JN Winter, and AJ Jr Atkinson

Decreased intracellular compartmentalization of doxorubicin in cell lines expressing P-glycoprotein
J Pharmacol Exp Ther 1994 271: 1286-1290. [Abstract] [PDF]  

YH Lee, K Spuhler-Phillips, PK Randall, and SW Leslie

Effects of prenatal ethanol exposure on N-methyl-D-aspartate-mediated calcium entry into dissociated neurons
J Pharmacol Exp Ther 1994 271: 1291-1298. [Abstract] [PDF]  

D Krajnc, TA Wemlinger, NH Neff, and M Hadjiconstantinou

Neonatal hypoxia: early neurotransmitter responses and the consequences of treatment with GM1 ganglioside
J Pharmacol Exp Ther 1994 271: 1299-1305. [Abstract] [PDF]  

JJ Idanpaan-Heikkila, EA Kalso, and T Seppala

Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli
J Pharmacol Exp Ther 1994 271: 1306-1313. [Abstract] [PDF]  

A Wilkinson, M Courtney, A Westlind-Danielsson, G Hallnemo, and KE Akerman

Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow
J Pharmacol Exp Ther 1994 271: 1314-1319. [Abstract] [PDF]  

KT Delle Donne and PK Sonsalla

Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation
J Pharmacol Exp Ther 1994 271: 1320-1326. [Abstract] [PDF]  

M Ries, U Wenzel, and H Daniel

Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems
J Pharmacol Exp Ther 1994 271: 1327-1333. [Abstract] [PDF]  

S Verma, S Bhanot, and JH McNeill

Antihypertensive effects of metformin in fructose-fed hyperinsulinemic, hypertensive rats
J Pharmacol Exp Ther 1994 271: 1334-1337. [Abstract] [PDF]  

A Bjork, E Christensson, A Albinsson, B Gustafsson, E Pettersson, G Pettersson, J Svartengren, and G Andersson

In the search for a novel class of antipsychotic drugs: preclinical pharmacology of FG5803, a 1-piperazinecarboxamide derivative
J Pharmacol Exp Ther 1994 271: 1338-1347. [Abstract] [PDF]  

G Romey and M Lazdunski

Effects of a new class of calcium antagonists, SR33557 (fantofarone) and SR33805, on neuronal voltage-activated Ca++ channels
J Pharmacol Exp Ther 1994 271: 1348-1352. [Abstract] [PDF]  

C Cussac, M Rapp, E Mounetou, JC Madelmont, JC Maurizis, D Godeneche, JM Dupuy, J Sauzieres, JP Baudry, and A Veyre

Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea- resistant human malignant melanocytes
J Pharmacol Exp Ther 1994 271: 1353-1358. [Abstract] [PDF]  

K Amano, M Hori, H Ozaki, Y Matsuda, and H Karaki

Ca++ mobilization mediated by endothelin ETA receptor in endothelium of rabbit aortic valve
J Pharmacol Exp Ther 1994 271: 1359-1364. [Abstract] [PDF]  

RYu Yukhananov and AA Larson

Involvement of NMDA receptors in naloxone-induced contractions of the isolated guinea pig ileum after preincubation with morphine
J Pharmacol Exp Ther 1994 271: 1365-1370. [Abstract] [PDF]  

L Belardinelli, J Lu, D Dennis, J Martens, and JC Shryock

The cardiac effects of a novel A1-adenosine receptor agonist in guinea pig isolated heart
J Pharmacol Exp Ther 1994 271: 1371-1382. [Abstract] [PDF]  

F Fan, DR Compton, S Ward, L Melvin, and BR Martin

Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212
J Pharmacol Exp Ther 1994 271: 1383-1390. [Abstract] [PDF]  

G Schulteis, A Markou, LH Gold, L Stinus, and GF Koob

Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis
J Pharmacol Exp Ther 1994 271: 1391-1398. [Abstract] [PDF]  

DC Argentieri, DM Ritchie, MP Ferro, T Kirchner, MP Wachter, DW Anderson, ME Rosenthale, and RJ Capetola

Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile
J Pharmacol Exp Ther 1994 271: 1399-1408. [Abstract] [PDF]  

CP Cheng, K Pettersson, and WC Little

Effects of felodipine on left ventricular systolic and diastolic performance in congestive heart failure
J Pharmacol Exp Ther 1994 271: 1409-1417. [Abstract] [PDF]  

PR Farina, AG Graham, AF Hoffman, JM Watrous, P Borgeat, M Nadeau, G Hansen, RM Dinallo, J Adams, and CK Miao

BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils
J Pharmacol Exp Ther 1994 271: 1418-1426. [Abstract] [PDF]  

BE Daikh, JM Lasker, JL Raucy, and DR Koop

Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9
J Pharmacol Exp Ther 1994 271: 1427-1433. [Abstract] [PDF]  

KX Huang and JR Walters

Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output
J Pharmacol Exp Ther 1994 271: 1434-1443. [Abstract] [PDF]  

ME Reith and LL Coffey

Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts
J Pharmacol Exp Ther 1994 271: 1444-1452. [Abstract] [PDF]  

G Battaglia and TM Cabrera

Potentiation of 5-HT1A receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: evidence for gender differences
J Pharmacol Exp Ther 1994 271: 1453-1461. [Abstract] [PDF]  

SP Zhang, LW Zhou, and B Weiss

Oligodeoxynucleotide antisense to the D1 dopamine receptor mRNA inhibits D1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine
J Pharmacol Exp Ther 1994 271: 1462-1470. [Abstract] [PDF]  

O Yamamoto, Y Matsunaga, Y Shiba, N Haga, I Sano, and Z Itoh

Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs
J Pharmacol Exp Ther 1994 271: 1471-1476. [Abstract] [PDF]  

BL Tepperman, JF Brown, R Korolkiewicz, and BJ Whittle

Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge
J Pharmacol Exp Ther 1994 271: 1477-1482. [Abstract] [PDF]  

G Mehrke, XG Zong, V Flockerzi, and F Hofmann

The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L- type Ca++ channels
J Pharmacol Exp Ther 1994 271: 1483-1488. [Abstract] [PDF]  

CA Maggi, M Astolfi, S Giuliani, C Goso, S Manzini, S Meini, R Patacchini, V Pavone, C Pedone, and L Quartara

MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors
J Pharmacol Exp Ther 1994 271: 1489-1500. [Abstract] [PDF]  

RC Pitts and LA Dykstra

Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys
J Pharmacol Exp Ther 1994 271: 1501-1508. [Abstract] [PDF]  

E Yodoya, K Uemura, T Tenma, T Fujita, M Murakami, A Yamamoto, and S Muranishi

Enhanced permeability of tetragastrin across the rat intestinal membrane and its reduced degradation by acylation with various fatty acids
J Pharmacol Exp Ther 1994 271: 1509-1513. [Abstract] [PDF]  

P Wheelan, A Sala, G Folco, S Nicosia, JR Falck, RK Bhatt, and RC Murphy

Stereochemical analysis and biological activity of 3-hydroxy- leukotriene B4: a metabolite from ethanol-treated rat hepatocytes
J Pharmacol Exp Ther 1994 271: 1514-1519. [Abstract] [PDF]  

AG Shi and RC Deth

Precoupling of alpha-2B adrenergic receptors and G-proteins in transfected PC-12 cell membranes: influence of pertussis toxin and a lysine-directed cross-linker
J Pharmacol Exp Ther 1994 271: 1520-1527. [Abstract] [PDF]  

J Cleary, G Mikus, A Somogyi, and F Bochner

The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model
J Pharmacol Exp Ther 1994 271: 1528-1534. [Abstract] [PDF]  

T Kuwabara, Y Kato, S Kobayashi, H Suzuki, and Y Sugiyama

Nonlinear pharmacokinetics of a recombinant human granulocyte colony- stimulating factor derivative (nartograstim): species differences among rats, monkeys and humans
J Pharmacol Exp Ther 1994 271: 1535-1543. [Abstract] [PDF]  

M Thuong-Guyot, O Domarle, JJ Pocidalo, and G Hayem

Effects of fluoroquinolones on cultured articular chondrocytes flow cytometric analysis of free radical production
J Pharmacol Exp Ther 1994 271: 1544-1549. [Abstract] [PDF]  

IM Khan, P Taylor, and TL Yaksh

Stimulatory pathways and sites of action of intrathecally administered nicotinic agents
J Pharmacol Exp Ther 1994 271: 1550-1557. [Abstract] [PDF]  

S Uhlen, AC Porter, and RR Neubig

The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors
J Pharmacol Exp Ther 1994 271: 1558-1565. [Abstract] [PDF]  

Z Nie, SG Madamba, and GR Siggins

Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms
J Pharmacol Exp Ther 1994 271: 1566-1573. [Abstract] [PDF]  

TM Filtz, W Guan, RP Artymyshyn, M Facheco, C Ford, and PB Molinoff

Mechanisms of up-regulation of D2L dopamine receptors by agonists and antagonists in transfected HEK-293 cells
J Pharmacol Exp Ther 1994 271: 1574-1582. [Abstract] [PDF]  

CC Chien and GW Pasternak

Selective antagonism of opioid analgesia by a sigma system
J Pharmacol Exp Ther 1994 271: 1583-1590. [Abstract] [PDF]  

KW Hong, BY Rhim, YW Shin, and SE Yoo

Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta
J Pharmacol Exp Ther 1994 271: 1591-1596. [Abstract] [PDF]  

NH Chen and ME Reith

Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats
J Pharmacol Exp Ther 1994 271: 1597-1610. [Abstract] [PDF]  

G Wiemer, E Fink, W Linz, M Hropot, BE Scholkens, and P Wohlfart

Furosemide enhances the release of endothelial kinins, nitric oxide and prostacyclin
J Pharmacol Exp Ther 1994 271: 1611-1615. [Abstract] [PDF]  

A Pomes, E Rodriguez-Farre, and C Sunol

Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons
J Pharmacol Exp Ther 1994 271: 1616-1623. [Abstract] [PDF]  

T Watanabe and M Egawa

Effects of an antistroke agent MCl-186 on cerebral arachidonate cascade
J Pharmacol Exp Ther 1994 271: 1624-1629. [Abstract] [PDF]  

PJ Emmerson, MR Liu, JH Woods, and F Medzihradsky

Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes
J Pharmacol Exp Ther 1994 271: 1630-1637. [Abstract] [PDF]  

MA Casado, MA Sevilla, MJ Alonso, J Marin, and M Salaices

Muscarinic receptors involved in modulation of norepinephrine release and vasodilatation in guinea pig carotid arteries
J Pharmacol Exp Ther 1994 271: 1638-1646. [Abstract] [PDF]  

PA Rittenhouse, EA Bakkum, AD Levy, Q Li, M Carnes, and LD van de Kar

Evidence that ACTH secretion is regulated by serotonin2A/2C (5-HT2A/2C) receptors
J Pharmacol Exp Ther 1994 271: 1647-1655. [Abstract] [PDF]  

P Guillaume, J Gutkowska, and C Gianoulakis

Increased plasma atrial natriuretic peptide after acute injection of alcohol in rats
J Pharmacol Exp Ther 1994 271: 1656-1665. [Abstract] [PDF]  

S Matzno, M Gohda, M Eda, H Ebisu, S Uno, N Ishida, N Nakamura, and K Yamanouchi

A possible mechanism of action of a new potassium channel opener, AL0671, on lipid metabolism in obese Zucker rats
J Pharmacol Exp Ther 1994 271: 1666-1671. [Abstract] [PDF]  

R Igarashi, J Hoshino, A Ochiai, Y Morizawa, and Y Mizushima

Lecithinized superoxide dismutase enhances its pharmacologic potency by increasing its cell membrane affinity
J Pharmacol Exp Ther 1994 271: 1672-1677. [Abstract] [PDF]  

JK Staley, WL Hearn, AJ Ruttenber, CV Wetli, and DC Mash

High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims
J Pharmacol Exp Ther 1994 271: 1678-1685. [Abstract] [PDF]  

PY Law, TM McGinn, MJ Wick, LJ Erikson, C Evans, and HH Loh

Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density?
J Pharmacol Exp Ther 1994 271: 1686-1694. [Abstract] [PDF]  

LM Kamendulis and GB Corcoran

DNA as a critical target in toxic cell death: enhancement of dimethylnitrosamine cytotoxicity by DNA repair inhibitors
J Pharmacol Exp Ther 1994 271: 1695-1698. [Abstract] [PDF]  

GE Duncan, DJ Knapp, KY Little, and GR Breese

Neuroanatomical specificity and dose dependence in the time course of imipramine-induced beta adrenergic receptor down-regulation in rat brain
J Pharmacol Exp Ther 1994 271: 1699-1704. [Abstract] [PDF]  

P Patrignani, MR Panara, A Greco, O Fusco, C Natoli, S Iacobelli, F Cipollone, A Ganci, C Creminon, and J Maclouf

Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases
J Pharmacol Exp Ther 1994 271: 1705-1712. [Abstract] [PDF]  

JY Lee, Y Uchida, T Sakamoto, A Hirata, S Hasegawa, and F Hirata

Alteration of G protein levels in antigen-challenged guinea pigs
J Pharmacol Exp Ther 1994 271: 1713-1720. [Abstract] [PDF]  

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