ARTICLES:

MA Simmons, CR Schneider, and JE Krause

Regulation of the responses to gonadotropin-releasing hormone, muscarine and substance P in sympathetic neurons by changes in cellular constituents and intracellular application of peptide fragments of the substance P receptor
J Pharmacol Exp Ther 1994 271: 581-589. [Abstract] [PDF]  

B Yu and P Shinnick-Gallagher

Interleukin-1 beta inhibits synaptic transmission and induces membrane hyperpolarization in amygdala neurons
J Pharmacol Exp Ther 1994 271: 590-600. [Abstract] [PDF]  

ET Iwamoto and L Marion

Pharmacologic evidence that spinal muscarinic analgesia is mediated by an L-arginine/nitric oxide/cyclic GMP cascade in rats
J Pharmacol Exp Ther 1994 271: 601-608. [Abstract] [PDF]  

A Asplund, D Grant, and JO Karlsson

Mangafodipir (MnDPDP)-and MnCl2-induced endothelium-dependent relaxation in bovine mesenteric arteries
J Pharmacol Exp Ther 1994 271: 609-614. [Abstract] [PDF]  

EWE Jonsson and SE Dahlen

Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma
J Pharmacol Exp Ther 1994 271: 615-623. [Abstract] [PDF]  

JP Sullivan, MW Decker, JD Brioni, D Donnelly-Roberts, DJ Anderson, AW Bannon, CH Kang, P Adams, M Piattoni-Kaplan, and MJ Buckley

(+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors
J Pharmacol Exp Ther 1994 271: 624-631. [Abstract] [PDF]  

K Kon, E Krause, and H Gogelein

Inhibition of K+ channels by chlorpromazine in rat ventricular myocytes
J Pharmacol Exp Ther 1994 271: 632-637. [Abstract] [PDF]  

G Mittleman, AL Rosner, and CL Schaub

Polydipsia and dopamine: behavioral effects of dopamine D1 and D2 receptor agonists and antagonists
J Pharmacol Exp Ther 1994 271: 638-650. [Abstract] [PDF]  

X Yang and JJ Buccafusco

Effect of chronic central treatment with the acetylcholine analog methylcarbamylcholine on cortical nicotinic receptors: correlation between receptor changes and behavioral function
J Pharmacol Exp Ther 1994 271: 651-659. [Abstract] [PDF]  

M Orihata and SK Sarna

Inhibition of nitric oxide synthase delays gastric emptying of solid meals
J Pharmacol Exp Ther 1994 271: 660-670. [Abstract] [PDF]  

JK Williams, YD Kim, MR Adams, MF Chen, AK Myers, and PW Ramwell

Effects of estrogen on cardiovascular responses of premenopausal monkeys
J Pharmacol Exp Ther 1994 271: 671-676. [Abstract] [PDF]  

RP Irwin, SZ Lin, MA Rogawski, RH Purdy, and SM Paul

Steroid potentiation and inhibition of N-methyl-D-aspartate receptor- mediated intracellular Ca++ responses: structure-activity studies
J Pharmacol Exp Ther 1994 271: 677-682. [Abstract] [PDF]  

SM Evans, JR 2nd Troisi, and RR Griffiths

Tandospirone and alprazolam: comparison of behavioral effects and abuse liability in humans
J Pharmacol Exp Ther 1994 271: 683-694. [Abstract] [PDF]  

K Kuratani, H Kodama, and I Yamaguchi

The differential roles of sympathetic nerve activity in the pathogenesis of antral and corpus lesions induced by indomethacin in rats
J Pharmacol Exp Ther 1994 271: 695-702. [Abstract] [PDF]  

M Sugiura, Y Shoyama, H Saito, and K Abe

Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in vivo
J Pharmacol Exp Ther 1994 271: 703-707. [Abstract] [PDF]  

JJ McGuire, DJ Anderson, and BM Bennett

Inhibition of the biotransformation and pharmacological actions of glyceryl trinitrate by the flavoprotein inhibitor, diphenyleneiodonium sulfate
J Pharmacol Exp Ther 1994 271: 708-714. [Abstract] [PDF]  

TF Burke, JH Woods, JW Lewis, and F Medzihradsky

Irreversible opioid antagonist effects of clocinnamox on opioid analgesia and mu receptor binding in mice
J Pharmacol Exp Ther 1994 271: 715-721. [Abstract] [PDF]  

WJ Wu, RM Wolcott, and SB Pruett

Ethanol decreases the number and activity of splenic natural killer cells in a mouse model for binge drinking
J Pharmacol Exp Ther 1994 271: 722-729. [Abstract] [PDF]  

NJ Lodge

Direct vasoconstrictor effects of sandimmune (cyclosporine A) are mediated by its vehicle cremophor EL: inhibition by the thromboxane A2/prostaglandin endoperoxide receptor antagonist ifetroban
J Pharmacol Exp Ther 1994 271: 730-734. [Abstract] [PDF]  

MF O'Rourke, LJ Iversen, JW Lomasney, and DB Bylund

Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors
J Pharmacol Exp Ther 1994 271: 735-740. [Abstract] [PDF]  

SS Hedge, TM Moy, MR Perry, M Loeb, and RM Eglen

Evidence for the involvement of 5-hydroxytryptamine 4 receptors in 5- hydroxytryptophan-induced diarrhea in mice
J Pharmacol Exp Ther 1994 271: 741-747. [Abstract] [PDF]  

HM Vargas, L Zhou, and AJ Gorman

Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat
J Pharmacol Exp Ther 1994 271: 748-754. [Abstract] [PDF]  

P Nambi, N Elshourbagy, HL Wu, M Pullen, EH Ohlstein, DP Brooks, MA Lago, JD Elliott, JG Gleason, and RR Jr Ruffolo

Nonpeptide endothelin receptor antagonists. I. Effects on binding and signal transduction on human endothelinA and endothelinB receptors
J Pharmacol Exp Ther 1994 271: 755-761. [Abstract] [PDF]  

EH Ohlstein, GR Jr Beck, SA Douglas, P Nambi, MA Lago, JG Gleason, RR Jr Ruffolo, G Feuerstein, and JD Elliott

Nonpeptide endothelin receptor antagonists. II. Pharmacological characterization of SB 209670
J Pharmacol Exp Ther 1994 271: 762-768. [Abstract] [PDF]  

DP Brooks, PD dePalma, M Gellai, P Nambi, EH Ohlstein, JD Elliott, JG Gleason, and RR Jr Ruffolo

Nonpeptide endothelin receptor antagonists. III. Effect of SB 209670 and BQ123 on acute renal failure in anesthetized dogs
J Pharmacol Exp Ther 1994 271: 769-775. [Abstract] [PDF]  

RB McCall, NA Escandon, LT Harris, and ME Clement

Tolerance development to the vagal-mediated bradycardia produced by 5- HT1A receptor agonists
J Pharmacol Exp Ther 1994 271: 776-781. [Abstract] [PDF]  

JL Ellis and ND Conanan

Effect of potassium channel blockers on relaxations to a nitric oxide donor and to nonadrenergic nerve stimulation in guinea pig trachea
J Pharmacol Exp Ther 1994 271: 782-786. [Abstract] [PDF]  

VP Bakshi, NR Swerdlow, and MA Geyer

Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response
J Pharmacol Exp Ther 1994 271: 787-794. [Abstract] [PDF]  

MW Lutz, PH Morgan, MK James, PL Feldman, MF Brackeen, AP Lahey, SV James, JM Bilotta, and JC Pressley

A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesics
J Pharmacol Exp Ther 1994 271: 795-803. [Abstract] [PDF]  

VJ Gorbea-Oppliger, MG Melaragno, GS Potter, RL Petit, and GD Fink

Time course of losartan blockade of angiotensin II hypertension versus blockade of angiotensin II fast pressor effects
J Pharmacol Exp Ther 1994 271: 804-810. [Abstract] [PDF]  

BJ Undem, SN Meeker, and J Chen

Inhibition of neurally mediated nonadrenergic, noncholinergic contractions of guinea pig bronchus by isozyme-selective phosphodiesterase inhibitors
J Pharmacol Exp Ther 1994 271: 811-817. [Abstract] [PDF]  

X Gao, CA Buffington, and JL Au

Effect of interstitial cystitis on drug absorption from urinary bladder
J Pharmacol Exp Ther 1994 271: 818-823. [Abstract] [PDF]  

MR James-Kracke, RB Sexe, and SD Shukla

Picomolar platelet-activating factor mobilizes Ca to change platelet shape without activating phospholipase C or protein kinase C; simultaneous fluorometric measurement of intracellular free Ca concentration and aggregation
J Pharmacol Exp Ther 1994 271: 824-831. [Abstract] [PDF]  

SW Watts, DA Cox, BG Johnson, DD Schoepp, and ML Cohen

Contractile serotonin-2A receptor signal transduction in guinea pig trachea: importance of protein kinase C and extracellular and intracellular calcium but not phosphoinositide hydrolysis
J Pharmacol Exp Ther 1994 271: 832-844. [Abstract] [PDF]  

JC Wanstall

In vitro hypoxia attenuates vasorelaxation by potassium channel opening drugs and nitroprusside in isolated pulmonary arteries from rats
J Pharmacol Exp Ther 1994 271: 845-851. [Abstract] [PDF]  

KM Tramposch, FH Chilton, PL Stanley, RC Franson, MB Havens, DO Nettleton, LB Davern, IM Darling, and RJ Bonney

Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity
J Pharmacol Exp Ther 1994 271: 852-859. [Abstract] [PDF]  

E Koyama, DR Sohn, SG Shin, K Chiba, JG Shin, YH Kim, H Echizen, and T Ishizaki

Metabolic disposition of imipramine in oriental subjects: relation to metoprolol alpha-hydroxylation and S-mephenytoin 4'-hydroxylation phenotypes
J Pharmacol Exp Ther 1994 271: 860-867. [Abstract] [PDF]  

EV Mishina, J Binder, JW Kupiec-Weglinski, and WJ Jusko

Effect of liposomal methylprednisolone on heart allograft survival and immune function in rats
J Pharmacol Exp Ther 1994 271: 868-874. [Abstract] [PDF]  

RB McCall, AG Romero, MJ Bienkowski, DW Harris, JC McGuire, MF Piercey, ME Shuck, MW Smith, KA Svensson, and PJ Schreur

Characterization of U-92016A as a selective, orally active, high intrinsic activity 5-hydroxytryptamine1A agonist
J Pharmacol Exp Ther 1994 271: 875-883. [Abstract] [PDF]  

Y Itoh, T Ogasawara, T Mushiroi, A yamazaki, Y Ukai, and K Kimura

Effect of NS-3, a thyrotropin-releasing hormone analog, on in vivo acetylcholine release in rat brain: regional differences and its sites of action
J Pharmacol Exp Ther 1994 271: 884-890. [Abstract] [PDF]  

CM Maciag, AR Logue, WJ Tinker, JA Saydoff, SW Tam, and R Zaczek

Studies on the role of K+, Cl- and Na+ ion permeabilities in the acetylcholine release enhancing effects of linopirdine (DuP 996) in rat cortical slices
J Pharmacol Exp Ther 1994 271: 891-897. [Abstract] [PDF]  

TK Machu and RA Harris

Alcohols and anesthetics enhance the function of 5-hydroxytryptamine3 receptors expressed in Xenopus laevis oocytes
J Pharmacol Exp Ther 1994 271: 898-905. [Abstract] [PDF]  

JR Hammond

Functional reconstitution of pharmacologically distinct subtypes of nucleoside transporters in liposomal membranes
J Pharmacol Exp Ther 1994 271: 906-917. [Abstract] [PDF]  

LM Hryhorenko, Z Woskowska, and JA Fox-Threlkeld

Nitric oxide (NO) inhibits release of acetylcholine from nerves of isolated circular muscle of the canine ileum: relationship to motility and release of nitric oxide
J Pharmacol Exp Ther 1994 271: 918-926. [Abstract] [PDF]  

O Laneuville, DK Breuer, DL Dewitt, T Hla, CD Funk, and WL Smith

Differential inhibition of human prostaglandin endoperoxide H synthases- 1 and -2 by nonsteroidal anti-inflammatory drugs
J Pharmacol Exp Ther 1994 271: 927-934. [Abstract] [PDF]  

QY Liu, E Karpinski, and PK Pang

The L-type calcium channel current is increased by alpha-1 adrenoceptor activation in neonatal rat ventricular cells
J Pharmacol Exp Ther 1994 271: 935-943. [Abstract] [PDF]  

QY Liu, E Karpinski, and PK Pang

L-channel modulation by alpha-1 adrenoceptor activation in neonatal rat ventricular cells: intracellular mechanisms
J Pharmacol Exp Ther 1994 271: 944-951. [Abstract] [PDF]  

CB Unal, MD Owen, and WR Millington

Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing
J Pharmacol Exp Ther 1994 271: 952-958. [Abstract] [PDF]  

EA Walker, MM Makhay, JD House, and AM Young

In vivo apparent pA2 analysis for naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats
J Pharmacol Exp Ther 1994 271: 959-968. [Abstract] [PDF]  

B Hitzemann, K Dains, S Kanes, and R Hitzemann

Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy
J Pharmacol Exp Ther 1994 271: 969-976. [Abstract] [PDF]  

S Zalcman, JM Green-Johnson, L Murray, W Wan, DM Nance, and AH Greenberg

Interleukin-2-induced enhancement of an antigen-specific IgM plaque- forming cell response is mediated by the sympathetic nervous system
J Pharmacol Exp Ther 1994 271: 977-982. [Abstract] [PDF]  

E Sehic, Y Ruan, and KU Malik

Attenuation by alpha,beta-methylenadenosine-5'-triphosphate of periarterial nerve stimulation-induced renal vasoconstriction is not due to desensitization of purinergic receptors
J Pharmacol Exp Ther 1994 271: 983-992. [Abstract] [PDF]  

LR Gerak, ER Butelman, JH Woods, and CP France

Antinociceptive and respiratory effects of nalbuphine in rhesus monkeys
J Pharmacol Exp Ther 1994 271: 993-999. [Abstract] [PDF]  

JL Goudreau, EJ Wagner, KJ Lookingland, and KE Moore

gamma-Aminobutyric acid receptor-mediated regulation of periventricular- hypophysial dopaminergic neurons: possible role in mediating stress- and 5-hydroxytryptamine-induced decreases in neuronal activity
J Pharmacol Exp Ther 1994 271: 1000-1006. [Abstract] [PDF]  

GA Knock, MH Sullivan, A McCarthy, MG Elder, JM Polak, and J Wharton

Angiotensin II (AT1) vascular binding sites in human placentae from normal-term, preeclamptic and growth retarded pregnancies
J Pharmacol Exp Ther 1994 271: 1007-1015. [Abstract] [PDF]  

PK Rangachari and T Prior

Functional subtyping of histamine receptors on the canine proximal colonic mucosa
J Pharmacol Exp Ther 1994 271: 1016-1026. [Abstract] [PDF]  

S Takano, S Gately, JB Jiang, and S Brem

A diaminoantraquinone inhibitor of angiogenesis
J Pharmacol Exp Ther 1994 271: 1027-1033. [Abstract] [PDF]  

DD D'Angelo, MG Davis, S Ali, and GW 2nd Dorn

Cloning and pharmacologic characterization of a thromboxane A2 receptor from K562 (human chronic myelogenous leukemia) cells
J Pharmacol Exp Ther 1994 271: 1034-1041. [Abstract] [PDF]  

EA Thomas and FJ Ehlert

Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis
J Pharmacol Exp Ther 1994 271: 1042-1050. [Abstract] [PDF]  

SM Roberts, RD Harbison, and RC James

Methamphetamine potentiation of carbon tetrachloride hepatotoxicity in mice
J Pharmacol Exp Ther 1994 271: 1051-1057. [Abstract] [PDF]  

GS Robertson, H Matsumura, and HC Fibiger

Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity
J Pharmacol Exp Ther 1994 271: 1058-1066. [Abstract] [PDF]  

NA Pampori and BH Shapiro

Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate
J Pharmacol Exp Ther 1994 271: 1067-1073. [Abstract] [PDF]  

H Farrington, F Mendelsohn, S Chan, L Reinlib, and SE Guggino

Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids
J Pharmacol Exp Ther 1994 271: 1074-1079. [Abstract] [PDF]  

CJ Kirk, NL Reddy, JB Fischer, TC Wolcott, AG Knapp, and RN McBurney

In vitro neuroprotection by substituted guanidines with varying affinities for the N-methyl-D-aspartate receptor ionophore and for sigma sites
J Pharmacol Exp Ther 1994 271: 1080-1085. [Abstract] [PDF]  

PM Lacal, A Puglianiello, E Bonmassar, and C D'Onofrio

Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. I. Cell differentiation determines sensitivity to prostaglandins and virus infection
J Pharmacol Exp Ther 1994 271: 1086-1095. [Abstract] [PDF]  

PM Lacal, C Amici, E Bonmassar, and C D'Onofrio

Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. II. Regulation of synthesis of inducible p72 heat shock protein
J Pharmacol Exp Ther 1994 271: 1096-1102. [Abstract] [PDF]  

CA Branch and MM Knuepfer

Causes of differential cardiovascular sensitivity to cocaine. II: Sympathetic, metabolic and cardiac effects
J Pharmacol Exp Ther 1994 271: 1103-1113. [Abstract] [PDF]  

MB Grisham, RD Specian, and TE Zimmerman

Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis
J Pharmacol Exp Ther 1994 271: 1114-1121. [Abstract] [PDF]  

MS Grotewiel, H Chu, and E Sanders-Bush

m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts
J Pharmacol Exp Ther 1994 271: 1122-1126. [Abstract] [PDF]  

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