ARTICLES:

M Gekle, S Mildenberger, R Freudinger, and S Silbernagl

The mycotoxin ochratoxin-A impairs protein uptake in cells derived from the proximal tubule of the kidney (opossum kidney cells)
J Pharmacol Exp Ther 1994 271: 1-6. [Abstract] [PDF]  

U Scheurer, E Drack, and F Halter

Substance P activates rat colonic motility via excitatory and inhibitory neural pathways and direct action on muscles
J Pharmacol Exp Ther 1994 271: 7-13. [Abstract] [PDF]  

K Niiya, S Uchida, T Tsuji, and RA Olsson

Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists
J Pharmacol Exp Ther 1994 271: 14-19. [Abstract] [PDF]  

M Oshita, Y Takei, S Kawano, H Fusamoto, and T Kamada

Protective effect of ebselen on constrictive hepatic vasculature: prevention of alcohol-induced effects on portal pressure in perfused livers
J Pharmacol Exp Ther 1994 271: 20-24. [Abstract] [PDF]  

SD Donevan, S Yamaguchi, and MA Rogawski

Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3- benzodiazepines: relationship to anticonvulsant activity
J Pharmacol Exp Ther 1994 271: 25-29. [Abstract] [PDF]  

GA Skeen, HS White, and RE Twyman

The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)- evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel
J Pharmacol Exp Ther 1994 271: 30-38. [Abstract] [PDF]  

MB Parrish, KD Rainsford, DM Johnson, and EE Daniel

NK1 receptors mediated release of 6-keto-PGF1 alpha from the ex vivo perfused canine ileum
J Pharmacol Exp Ther 1994 271: 39-47. [Abstract] [PDF]  

KL Preston and GE Bigelow

Drug discrimination assessment of agonist-antagonist opioids in humans: a three-choice saline-hydromorphone-butorphanol procedure
J Pharmacol Exp Ther 1994 271: 48-60. [Abstract] [PDF]  

TD Hexum, J Zheng, and J Zhu

Neuropeptide Y inhibition of nicotinic receptor-mediated chromaffin cell secretion
J Pharmacol Exp Ther 1994 271: 61-66. [Abstract] [PDF]  

LJ Chandler, NJ Guzman, C Sumners, and FT Crews

Magnesium and zinc potentiate ethanol inhibition of N-methyl-D- aspartate-stimulated nitric oxide synthase in cortical neurons
J Pharmacol Exp Ther 1994 271: 67-75. [Abstract] [PDF]  

KA Sluka, WD Willis, and KN Westlund

Inflammation-induced release of excitatory amino acids is prevented by spinal administration of a GABAA but not by a GABAB receptor antagonist in rats
J Pharmacol Exp Ther 1994 271: 76-82. [Abstract] [PDF]  

S Prisco, S Pagannone, and E Esposito

Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo
J Pharmacol Exp Ther 1994 271: 83-90. [Abstract] [PDF]  

L Perrier, M Bourrie, E Marti, C Tronquet, D Masse, Y Berger, J Magdalou, and G Fabre

In vitro N-glucuronidation of SB 47436 (BMS 186295), a new AT1 nonpeptide angiotensin II receptor antagonist, by rat, monkey and human hepatic microsomal fractions
J Pharmacol Exp Ther 1994 271: 91-99. [Abstract] [PDF]  

K Nomura, N Maeda, T Yoshino, and I Yamaguchi

A mechanism of 5-HT3 receptor mediation is involved etiologically in the psychological stress lesion the stomach of the mouse
J Pharmacol Exp Ther 1994 271: 100-106. [Abstract] [PDF]  

C Dominice, MN Dufour, N Patino, O Manzoni, E Grazzini, P Jouin, and G Guillon

Dual effects of nordidemnin on WRK1 cells: inhibition of phosphoinositide metabolism and cell proliferation
J Pharmacol Exp Ther 1994 271: 107-117. [Abstract] [PDF]  

LJ Murphey and GD Olsen

Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression
J Pharmacol Exp Ther 1994 271: 118-124. [Abstract] [PDF]  

AC Collins, Y Luo, S Selvaag, and MJ Marks

Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion
J Pharmacol Exp Ther 1994 271: 125-133. [Abstract] [PDF]  

M Buerke, AS Weyrich, T Murohara, C Queen, CK Klingbeil, MS Co, and AM Lefer

Humanized monoclonal antibody DREG-200 directed against I-selectin protects in feline myocardial reperfusion injury
J Pharmacol Exp Ther 1994 271: 134-142. [Abstract] [PDF]  

CS Aulakh, P Mazzola-Pomietto, JL Hill, and DL Murphy

Role of various 5-HT receptor subtypes in mediating neuroendocrine effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) in rats
J Pharmacol Exp Ther 1994 271: 143-148. [Abstract] [PDF]  

P Cuq, R Magous, and JP Bali

Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum
J Pharmacol Exp Ther 1994 271: 149-155. [Abstract] [PDF]  

T Yamamoto, N Shimoyama, H Asano, and T Mizuguchi

Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin- B receptor agonist
J Pharmacol Exp Ther 1994 271: 156-163. [Abstract] [PDF]  

DA Finn and KW Gee

The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid
J Pharmacol Exp Ther 1994 271: 164-170. [Abstract] [PDF]  

H Vidrio

Potentiation of cardiovascular responses to hydralazine by diverse hydrazine derivatives
J Pharmacol Exp Ther 1994 271: 171-175. [Abstract] [PDF]  

AM Gillis, M Choi, HJ Mathison, and HG Parsons

Influence of dietary fat on the pharmacodynamics of quinidine, procainamide and tocainide in isolated perfused rabbit hearts
J Pharmacol Exp Ther 1994 271: 176-183. [Abstract] [PDF]  

JS Pasnani and GR Ferrier

Pro- and antiarrhythmic effects of d-sotalol and dl-sotalol in an isolated tissue model of ischemia and reperfusion
J Pharmacol Exp Ther 1994 271: 184-192. [Abstract] [PDF]  

H Defacque, J Dornand, T Commes, S Cabane, C Sevilla, and J Marti

Different combinations of retinoids and vitamin D3 analogs efficiently promote growth inhibition and differentiation of myelomonocytic leukemia cell lines
J Pharmacol Exp Ther 1994 271: 193-199. [Abstract] [PDF]  

BS Stewart, GA Lemaire, JD Roache, and RA Meisch

Establishing benzodiazepines as oral reinforcers: midazolam and diazepam self-administration in rhesus monkeys
J Pharmacol Exp Ther 1994 271: 200-211. [Abstract] [PDF]  

GM Gonzalez-Alvear and LL Werling

Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands
J Pharmacol Exp Ther 1994 271: 212-219. [Abstract] [PDF]  

S Desai, T Hadlock, C Messam, R Chafetz, and G Strichartz

Ionization and adsorption of a series of local anesthetics in detergent micelles: studies of drug fluorescence
J Pharmacol Exp Ther 1994 271: 220-228. [Abstract] [PDF]  

SR Doctrow, SM Abelleira, LA Curry, R Heller-Harrison, JW Kozarich, B Malfroy, LA McCarroll, KG Morgan, AR Morrow, and GF Musso

The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells
J Pharmacol Exp Ther 1994 271: 229-237. [Abstract] [PDF]  

ZY Friedman

The antitumor agent tamoxifen inhibits breakdown of polyphosphoinositides in GH4C1 cells
J Pharmacol Exp Ther 1994 271: 238-245. [Abstract] [PDF]  

JM O'Donnell, S Frith, and J Wilkins

Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol
J Pharmacol Exp Ther 1994 271: 246-254. [Abstract] [PDF]  

GE Torres, IL Holt, and R Andrade

Antagonists of 5-HT4 receptor-mediated responses in adult hippocampal neurons
J Pharmacol Exp Ther 1994 271: 255-261. [Abstract] [PDF]  

P Fan, S Visentin, and FF Weight

Effects of cocaine on the serotonin-induced inward current in rat nodose ganglion neurons
J Pharmacol Exp Ther 1994 271: 262-266. [Abstract] [PDF]  

C Labbe-Jullie, S Deschaintres, D Gully, G Le Fur, and P Kitabgi

Effect of the nonpeptide neurotensin antagonist, SR 48692, and two enantiomeric analogs, SR 48527 and SR 49711, on neurotensin binding and contractile responses in guinea pig ileum and colon
J Pharmacol Exp Ther 1994 271: 267-276. [Abstract] [PDF]  

T Shibamoto, S Chakder, and S Rattan

Role of hypogastric nerve activity in opossum internal anal sphincter function: influence of surgical and chemical denervation
J Pharmacol Exp Ther 1994 271: 277-284. [Abstract] [PDF]  

HW Broening, L Bacon, and W Jr Slikker

Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine
J Pharmacol Exp Ther 1994 271: 285-293. [Abstract] [PDF]  

P Bauco and RA Wise

Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: examination of repeated treatment
J Pharmacol Exp Ther 1994 271: 294-301. [Abstract] [PDF]  

T Sawanobori, H Adaniya, T Namiki, and M Hiraoka

Rate-dependent effects of sematilide on action potential duration in isolated guinea pig ventricular myocytes
J Pharmacol Exp Ther 1994 271: 302-310. [Abstract] [PDF]  

J Mattana, N Gibbons, and PC Singhal

Cocaine interacts with macrophages to modulate mesangial cell proliferation
J Pharmacol Exp Ther 1994 271: 311-318. [Abstract] [PDF]  

YQ Xu, WJ Jr Crumb, and CW Clarkson

Cocaethylene, a metabolite of cocaine and ethanol, is a potent blocker of cardiac sodium channels
J Pharmacol Exp Ther 1994 271: 319-325. [Abstract] [PDF]  

F Zhang and AH Morice

Effect of levcromakalim on hypoxia-, KCl- and prostaglandin F2 alpha- induced contractions in isolated rat pulmonary artery
J Pharmacol Exp Ther 1994 271: 326-333. [Abstract] [PDF]  

SS Osmanovic and SA Shefner

Ethanol enhances inward rectification in rat locus ceruleus neurons by increasing the extracellular potassium concentration
J Pharmacol Exp Ther 1994 271: 334-342. [Abstract] [PDF]  

I Krisch, B Bole-Vunduk, M Pepelnak, B Lavric, A Ocvirk, MV Budihna, and D Sket

Pharmacological studies with two new ergoline derivatives, the potential antipsychotics LEK-8829 and LEK-8841
J Pharmacol Exp Ther 1994 271: 343-352. [Abstract] [PDF]  

JD Brioni, AB O'Neill, DJ Kim, MJ Buckley, MW Decker, and SP Arneric

Anxiolytic-like effects of the novel cholinergic channel activator ABT- 418
J Pharmacol Exp Ther 1994 271: 353-361. [Abstract] [PDF]  

X Xu, TD Tsai, J Wang, EW Lee, and KS Lee

Modulation of three types of K+ currents in canine coronary artery smooth muscle cells by NS-004, or 1-(2'-hydroxy-5'-chlorophenyl)-5- trifluoromethyl-2(3H) benzimidazolone
J Pharmacol Exp Ther 1994 271: 362-369. [Abstract] [PDF]  

H Shimamura, H Suzuki, M Hanano, A Suzuki, O Tagaya, T Horie, and Y Sugiyama

Multiple systems for the biliary excretion of organic anions in rats: liquiritigenin conjugates as model compounds
J Pharmacol Exp Ther 1994 271: 370-378. [Abstract] [PDF]  

H Miyahara, Y Kawai, and T Ohhashi

5-Hydroxytryptamine-2 and -4 receptors located on bovine isolated mesenteric lymphatics
J Pharmacol Exp Ther 1994 271: 379-385. [Abstract] [PDF]  

HP Voss, S Shukrula, TS Wu, D Donnell, and A Bast

A functional beta-2 adrenoceptor-mediated chronotropic response in isolated guinea pig heart tissue: selectivity of the potent beta-2 adrenoceptor agonist TA 2005
J Pharmacol Exp Ther 1994 271: 386-389. [Abstract] [PDF]  

GC Smith, RA Coleman, and JC McGrath

Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus
J Pharmacol Exp Ther 1994 271: 390-396. [Abstract] [PDF]  

F Ueda, Y Kameda, O Yamamoto, and Y Shibata

Beta-adrenergic regulation of gap-junctional intercellular communication in cultured rabbit gastric epithelial cells
J Pharmacol Exp Ther 1994 271: 397-402. [Abstract] [PDF]  

FX Beck, A Ohno, A Dorge, and K Thurau

Loop diuretics affect transcellular electrolyte transport in cells of the distal convoluted tubule
J Pharmacol Exp Ther 1994 271: 403-407. [Abstract] [PDF]  

JF Ewing, VS Raju, and MD Maines

Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3':5'-guanosine monophosphate
J Pharmacol Exp Ther 1994 271: 408-414. [Abstract] [PDF]  

LA Erickson, PD Bonin, DG Wishka, J Morris, RJ Dalga, DJ Williams, GJ Wilson, JL Hoover, CA Simmons, and SJ Humphrey

In vitro and in vivo inhibition of rat vascular smooth muscle cell migration and proliferation by a 2-aminochromone U-86983
J Pharmacol Exp Ther 1994 271: 415-421. [Abstract] [PDF]  

P Butkerait, HY Wang, and E Friedman

Increases in guanine nucleotide binding to striatal G proteins is associated with dopamine receptor supersensitivity
J Pharmacol Exp Ther 1994 271: 422-428. [Abstract] [PDF]  

CP Sung, AJ Arleth, BL Storer, and EH Ohlstein

Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle
J Pharmacol Exp Ther 1994 271: 429-437. [Abstract] [PDF]  

P Liu, SL Vonderfecht, GM McGuire, MA Fisher, A Farhood, and H Jaeschke

The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats
J Pharmacol Exp Ther 1994 271: 438-445. [Abstract] [PDF]  

DJ Crutchley, LB Conanan, and BG Que

Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alpha and interleukin-1 beta in human monocytic THP-1 cells
J Pharmacol Exp Ther 1994 271: 446-451. [Abstract] [PDF]  

X Ligneau, M Garbarg, ML Vizuete, J Diaz, K Purand, H Stark, W Schunack, and JC Schwartz

[125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors
J Pharmacol Exp Ther 1994 271: 452-459. [Abstract] [PDF]  

KM Merchant, DJ Dobie, FM Filloux, M Totzke, M Aravagiri, and DM Dorsa

Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions
J Pharmacol Exp Ther 1994 271: 460-471. [Abstract] [PDF]  

JP Wagner, FJ Seidler, SE Lappi, EC McCook, and TA Slotkin

Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression
J Pharmacol Exp Ther 1994 271: 472-483. [Abstract] [PDF]  

DW Bonhaus, DN Loury, LB Jakeman, SA Hsu, ZP To, E Leung, KD Zeitung, RM Eglen, and EH Wong

[3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma- 1 but not sigma-2 binding sites in guinea pig brain
J Pharmacol Exp Ther 1994 271: 484-493. [Abstract] [PDF]  

M Alkondon, S Reinhardt, C Lobron, B Hermsen, A Maelicke, and EX Albuquerque

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization
J Pharmacol Exp Ther 1994 271: 494-506. [Abstract] [PDF]  

D Gelperin, D Mann, J del Valle, and JW Wiley

Bradykinin (Bk) increases cytosolic calcium in cultured rat myenteric neurons via Bk-2 type receptors coupled to mobilization of extracellular and intracellular sources of calcium: evidence that calcium influx is prostaglandin dependent
J Pharmacol Exp Ther 1994 271: 507-514. [Abstract] [PDF]  

ME Fitzsimmons, RB Baggs, and MW Anders

Nephrotoxicity and hepatotoxicity of 5,6-dichloro-4-thia-5-hexenoic acid: evidence for fatty acid beta-oxidation-dependent bioactivation
J Pharmacol Exp Ther 1994 271: 515-523. [Abstract] [PDF]  

ZH Meng and MS Dar

Intrastriatal Ro15-4513 functionally antagonizes ethanol-induced motor incoordination and striatal adenosinergic modulation of ethanol-induced motor incoordination in rats
J Pharmacol Exp Ther 1994 271: 524-534. [Abstract] [PDF]  

J Neumann, P Boknik, S Herzig, W Schmitz, H Scholz, K Wiechen, and N Zimmermann

Biochemical and electrophysiological mechanisms of the positive inotropic effect of calyculin A, a protein phosphatase inhibitor
J Pharmacol Exp Ther 1994 271: 535-541. [Abstract] [PDF]  

MK Sapru, I Diamond, and AS Gordon

Adenosine receptors mediate cellular adaptation to ethanol in NG108-15 cells
J Pharmacol Exp Ther 1994 271: 542-548. [Abstract] [PDF]  

KE Thummel, DD Shen, TD Podoll, KL Kunze, WF Trager, PS Hartwell, VA Raisys, CL Marsh, JP McVicar, and DM Barr

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients
J Pharmacol Exp Ther 1994 271: 549-556. [Abstract] [PDF]  

KE Thummel, DD Shen, TD Podoll, KL Kunze, WF Trager, CE Bacchi, CL Marsh, JP McVicar, DM Barr, and JD Perkins

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation
J Pharmacol Exp Ther 1994 271: 557-566. [Abstract] [PDF]  

YW Liu, Y Asaoka, H Suzuki, T Yoshimoto, S Yamamoto, and WC Chang

Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells
J Pharmacol Exp Ther 1994 271: 567-573. [Abstract] [PDF]  

M Satoh, T Sakai, I Sano, K Fujikura, H Koyama, K Ohshima, Z Itoh, and S Omura

EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum
J Pharmacol Exp Ther 1994 271: 574-579. [Abstract] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.