ARTICLES:

WC Duane

Effects of lovastatin in humans on biliary lipid composition and secretion as a function of dosage and treatment interval
J Pharmacol Exp Ther 1994 270: 841-845. [Abstract] [PDF]  

PJ Riviere, X Pascaud, E Chevalier, and JL Junien

Fedotozine reversal of peritoneal-irritation-induced ileus in rats: possible peripheral action on sensory afferents
J Pharmacol Exp Ther 1994 270: 846-850. [Abstract] [PDF]  

YN Cheng, T Kiyosue, and M Arita

Effects of KT-362, a new antiarrhythmic agent, on membrane ionic currents of guinea pig ventricular myocytes
J Pharmacol Exp Ther 1994 270: 851-857. [Abstract] [PDF]  

JA Awad, RF Burk, and LJ 2nd Roberts

Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats
J Pharmacol Exp Ther 1994 270: 858-864. [Abstract] [PDF]  

JP Uetrecht, N Zahid, and D Whitfield

Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis
J Pharmacol Exp Ther 1994 270: 865-872. [Abstract] [PDF]  

BM Tune and CY Hsu

Toxicity of cephaloridine to carnitine transport and fatty acid metabolism in rabbit renal cortical mitochondria: structure-activity relationships
J Pharmacol Exp Ther 1994 270: 873-880. [Abstract] [PDF]  

K Yamada, S Nakayama, T Shiotani, T Hasegawa, and T Nabeshima

Possible involvement of the activation of voltage-sensitive calcium channels in the ameliorating effects of nefiracetam on scopolamine- induced impairment of performance in a passive avoidance task
J Pharmacol Exp Ther 1994 270: 881-892. [Abstract] [PDF]  

PL Martin and AA Potts

The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N- ethylcarboxamidoadenosine and N6-cyclopentyladenosine
J Pharmacol Exp Ther 1994 270: 893-899. [Abstract] [PDF]  

TH Chen, B Lee, and WH Hsu

Arginine vasopressin-stimulated insulin secretion and elevation of intracellular Ca++ concentration in rat insulinoma cells: influences of a phospholipase C inhibitor 1-[6-[[17 beta-methoxyestra-1,3,5(10)-trien- 17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U-73122) and a phospholipase A2 inhibitor N-(p-amylcinnamoyl)anthranilic acid
J Pharmacol Exp Ther 1994 270: 900-904. [Abstract] [PDF]  

D Saphier and JE Welch

Central stimulation of adrenocortical secretion by 5- hydroxytryptamine1A agonists is mediated by sympathomedullary activation
J Pharmacol Exp Ther 1994 270: 905-917. [Abstract] [PDF]  

JE Welch and D Saphier

Central and peripheral mechanisms in the stimulation of adrenocortical secretion by the 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4- iodophenyl)-2-aminopropane
J Pharmacol Exp Ther 1994 270: 918-928. [Abstract] [PDF]  

R Ciccocioppo, L Onori, E Messori, SM Candura, T Coccini, and M Tonini

Role of nitric oxide-dependent and -independent mechanisms in peristalsis and accommodation in the rabbit distal colon
J Pharmacol Exp Ther 1994 270: 929-937. [Abstract] [PDF]  

PJ Pauwels and C Palmier

Differential functional activity of 5-hydroxytryptamine receptor ligands and beta adrenergic receptor antagonists at 5- hydroxytryptamine1B receptor sites in Chinese hamster lung fibroblasts and opossum renal epithelial cells
J Pharmacol Exp Ther 1994 270: 938-945. [Abstract] [PDF]  

A Renouard, PS Widdowson, and MJ Millan

Multiple alpha 2 adrenergic receptor subtypes. I. Comparison of [3H]RX821002-labeled rat R alpha-2A adrenergic receptors in cerebral cortex to human H alpha2A adrenergic receptor and other populations of alpha-2 adrenergic subtypes
J Pharmacol Exp Ther 1994 270: 946-957. [Abstract] [PDF]  

MJ Millan, K Bervoets, JM Rivet, P Widdowson, A Renouard, S Le Marouille- Girardon, and A Gobert

Multiple alpha-2 adrenergic receptor subtypes. II. Evidence for a role of rat R alpha-2A adrenergic receptors in the control of nociception, motor behavior and hippocampal synthesis of noradrenaline
J Pharmacol Exp Ther 1994 270: 958-972. [Abstract] [PDF]  

M Breuiller-Fouche, V Heluy, T Fournier, and F Ferre

Endothelin receptors: binding and phosphoinositide breakdown in human myometrium
J Pharmacol Exp Ther 1994 270: 973-978. [Abstract] [PDF]  

MR Escorbar, LT Wong, and DS Sitar

Bicarbonate-dependent amantadine transport by rat renal cortical proximal and distal tubules
J Pharmacol Exp Ther 1994 270: 979-986. [Abstract] [PDF]  

SA Zimmerman, MV Jones, and NL Harrison

Potentiation of gamma-aminobutyric acidA receptor Cl- current correlates with in vivo anesthetic potency
J Pharmacol Exp Ther 1994 270: 987-991. [Abstract] [PDF]  

CP France and LR Gerak

Behavioral effects of 6-methylene naltrexone (nalmefene) in rhesus monkeys
J Pharmacol Exp Ther 1994 270: 992-999. [Abstract] [PDF]  

A Giovanni, BA Sieber, RE Heikkila, and PK Sonsalla

Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration
J Pharmacol Exp Ther 1994 270: 1000-1007. [Abstract] [PDF]  

A Giovanni, PK Sonsalla, and RE Heikkila

Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium
J Pharmacol Exp Ther 1994 270: 1008-1014. [Abstract] [PDF]  

KA Criswell, EL Stuenkel, and R Loch-Caruso

Lindane increases intracellular calcium in rat myometrial smooth muscle cells through modulation of inositol 1,4,5-trisphosphate-sensitive stores
J Pharmacol Exp Ther 1994 270: 1015-1024. [Abstract] [PDF]  

SS Negus, ER Butelman, KJ Chang, B DeCosta, G Winger, and JH Woods

Behavioral effects of the systemically active delta opioid agonist BW373U86 in rhesus monkeys
J Pharmacol Exp Ther 1994 270: 1025-1034. [Abstract] [PDF]  

S Ozaki, M Ihara, T Saeki, T Fukami, K Ishikawa, and M Yano

Endothelin ETB receptors couple to two distinct signaling pathways in porcine kidney epithelial LLC-PK1 cells
J Pharmacol Exp Ther 1994 270: 1035-1040. [Abstract] [PDF]  

P Terry, JM Witkin, and JL Katz

Pharmacological characterization of the novel discriminative stimulus effects of a low dose of cocaine
J Pharmacol Exp Ther 1994 270: 1041-1048. [Abstract] [PDF]  

KE Vanover and WL Woolverton

Behavioral effects of the dopamine autoreceptor agonist PD 128483 alone and in combination with cocaine
J Pharmacol Exp Ther 1994 270: 1049-1056. [Abstract] [PDF]  

A Keshavarzian, O Zorub, M Sayeed, G Urban, C Sweeney, D Winship, and J Fields

Acute ethanol inhibits calcium influxes into esophageal smooth but not striated muscle: a possible mechanism for ethanol-induced inhibition of esophageal contractility
J Pharmacol Exp Ther 1994 270: 1057-1062. [Abstract] [PDF]  

CK Jr Kost, P Li, CA Pfeifer, and EK Jackson

Telemetric blood pressure monitoring in benign 2-kidney, 1-clip renovascular hypertension: effect of chronic caffeine ingestion
J Pharmacol Exp Ther 1994 270: 1063-1070. [Abstract] [PDF]  

JC Hartman, GM Kurc, TG Hullinger, TM Wall, RM Sheehy, and RJ Shebuski

Inhibition of nitric oxide synthase prevents myocardial protection by ramiprilat
J Pharmacol Exp Ther 1994 270: 1071-1076. [Abstract] [PDF]  

S Greenberg, C McGowan, J Xie, and WR Summer

Selective pulmonary and venous smooth muscle relaxation by furosemide: a comparison with morphine
J Pharmacol Exp Ther 1994 270: 1077-1085. [Abstract] [PDF]  

JE Zadina, LM Harrison, LJ Ge, AJ Kastin, and SL Chang

Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH- SY5Y human neuroblastoma cells
J Pharmacol Exp Ther 1994 270: 1086-1096. [Abstract] [PDF]  

F Courjault-Gautier, D Hoet, D Leroy, and HJ Toutain

Dissimilar alterations of sodium-coupled uptake by platinum- coordination complexes in renal proximal tubular cells in primary culture
J Pharmacol Exp Ther 1994 270: 1097-1104. [Abstract] [PDF]  

JW Karanian, HY Kim, and N Jr Salem

Inhibitory effects of n-6 and n-3 hydroxy fatty acids on thromboxane (U46619)-induced smooth muscle contraction
J Pharmacol Exp Ther 1994 270: 1105-1109. [Abstract] [PDF]  

NK Mello, JH Mendelson, JM Drieze, SK Teoh, ML Kelly, and JW Sholar

Effects of dopamine on prolactin: interactions with cocaine self- administration by female rhesus monkeys
J Pharmacol Exp Ther 1994 270: 1110-1120. [Abstract] [PDF]  

L Fernandez, LD Boada, OP Luzardo, M Zumbado, JC Diaz-Chico, BN Diaz-Chico, and R Chirino

Ethinylestradiol interacts with liver microsomes and induces binding sites for steroid hormones in the male rat liver
J Pharmacol Exp Ther 1994 270: 1121-1126. [Abstract] [PDF]  

DO Freier and BA Fuchs

A mechanism of action for morphine-induced immunosuppression: corticosterone mediates morphine-induced suppression of natural killer cell activity
J Pharmacol Exp Ther 1994 270: 1127-1133. [Abstract] [PDF]  

SK Teoh, Z Sarnyai, JH Mendelson, NK Mello, SA Springer, JW Sholar, M Wapler, JC Kuehnle, and H Gelles

Cocaine effects on pulsatile secretion of ACTH in men
J Pharmacol Exp Ther 1994 270: 1134-1138. [Abstract] [PDF]  

KJ LePard and RL Jr Stephens

Serotonin inhibits gastric acid secretion through a 5- hydroxytryptamine1-like receptor in the rat
J Pharmacol Exp Ther 1994 270: 1139-1144. [Abstract] [PDF]  

T Oguro, Z Gregus, C Madhu, L Liu, and CD Klaassen

Molybdate depletes hepatic 3-phosphoadenosine 5-phosphosulfate and impairs the sulfation of acetaminophen in rats
J Pharmacol Exp Ther 1994 270: 1145-1151. [Abstract] [PDF]  

AF Hajj-Ali, TM Reilly, and PC Wong

Modulation of renal vasoconstrictor effect of NG-nitro-L-arginine in rabbit by angiotensin II and alpha-1 adrenergic receptor blockade
J Pharmacol Exp Ther 1994 270: 1152-1157. [Abstract] [PDF]  

G Yadid, K Pacak, IJ Kopin, and DS Goldstein

Endogenous serotonin stimulates striatal dopamine release in conscious rats
J Pharmacol Exp Ther 1994 270: 1158-1165. [Abstract] [PDF]  

LB Fernandes, WC Hubbard, and BJ Undem

Release of inflammatory mediators from guinea pig trachea by electrical field stimulation: lack of neuronal involvement
J Pharmacol Exp Ther 1994 270: 1166-1170. [Abstract] [PDF]  

HC Lee, JJ Cai, and H Yu

Effect of protein kinase C on cyclic 3',5'-adenosine monophosphate- dependent phosphodiesterase in hypertrophic cardiomyopathic hamster hearts
J Pharmacol Exp Ther 1994 270: 1171-1176. [Abstract] [PDF]  

FL Smith, DA Brase, DS Dombrowski, and WL Dewey

Endogenous opioids released by suspending mice by the tail selectively enhance spinal mu opioid analgesia
J Pharmacol Exp Ther 1994 270: 1177-1185. [Abstract] [PDF]  

FP Lacreta, JM Brennan, SL Nash, RL Comis, KD Tew, and PJ O'Dwyer

Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer
J Pharmacol Exp Ther 1994 270: 1186-1191. [Abstract] [PDF]  

K Yin, PV Halushka, YT Yan, and PY Wong

Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F- series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets
J Pharmacol Exp Ther 1994 270: 1192-1196. [Abstract] [PDF]  

DE Wesson and SJ Elliott

Xanthine oxidase inhibits transmembrane signal transduction in vascular endothelial cells
J Pharmacol Exp Ther 1994 270: 1197-1207. [Abstract] [PDF]  

SC Black, CS Schasteen, RH Weiss, DP Riley, EM Driscoll, and BR Lucchesi

Inhibition of in vivo myocardial ischemic and reperfusion injury by a synthetic manganese-based superoxide dismutase mimetic
J Pharmacol Exp Ther 1994 270: 1208-1215. [Abstract] [PDF]  

JE Caldwell, J Szenohradszky, V Segredo, PM Wright, C McLoughlin, ML Sharma, LD Gruenke, DM Fisher, and RD Miller

The pharmacodynamics and pharmacokinetics of the metabolite 3- desacetylvecuronium (ORG 7268) and its parent compound, vecuronium, in human volunteers
J Pharmacol Exp Ther 1994 270: 1216-1222. [Abstract] [PDF]  

TG Kokate, BE Svensson, and MA Rogawski

Anticonvulsant activity of neurosteroids: correlation with gamma- aminobutyric acid-evoked chloride current potentiation
J Pharmacol Exp Ther 1994 270: 1223-1229. [Abstract] [PDF]  

BK Tolliver, JK Belknap, WE Woods, and JM Carney

Genetic analysis of sensitization and tolerance to cocaine
J Pharmacol Exp Ther 1994 270: 1230-1238. [Abstract] [PDF]  

TS Gaginella, N Mascolo, AA Izzo, G Autore, and F Capasso

Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase
J Pharmacol Exp Ther 1994 270: 1239-1245. [Abstract] [PDF]  

KM Standifer, J Cheng, AI Brooks, CP Honrado, W Su, LM Visconti, JL Biedler, and GW Pasternak

Biochemical and pharmacological characterization of mu, delta and kappa 3 opioid receptors expressed in BE(2)-C neuroblastoma cells
J Pharmacol Exp Ther 1994 270: 1246-1255. [Abstract] [PDF]  

A Nishida, Y Takinami, H Yuki, A Kobayashi, S Akuzawa, T Kamato, H Ito, M Yamano, Y Nagakura, and K Miyata

YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4- benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats
J Pharmacol Exp Ther 1994 270: 1256-1261. [Abstract] [PDF]  

J Auta, P Giusti, A Guidotti, and E Costa

Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat
J Pharmacol Exp Ther 1994 270: 1262-1269. [Abstract] [PDF]  

MM Foreman, RW Fuller, K Rasmussen, DL Nelson, DO Calligaro, L Zhang, JE Barrett, RN Booher, CJ Jr Paget, and ME Flaugh

Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity
J Pharmacol Exp Ther 1994 270: 1270-1281. [Abstract] [PDF]  

M O'Donnell, RJ Garippa, N Rinaldi, WM Selig, B Simko, L Renzetti, SA Tannu, MA Wasserman, A Welton, and DR Bolin

Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part I: In vitro and in vivo bronchodilator studies
J Pharmacol Exp Ther 1994 270: 1282-1288. [Abstract] [PDF]  

M O'Donnell, RJ Garippa, N Rinaldi, WM Selig, JE Tocker, SA Tannu, MA Wasserman, A Welton, and DR Bolin

Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part II: Effect on in vitro and in vivo models of pulmonary anaphylaxis
J Pharmacol Exp Ther 1994 270: 1289-1294. [Abstract] [PDF]  

XP Zeng and E Burcher

Use of selective antagonists for further characterization of tachykinin NK-2, NK-1 and possible "septide-selective" receptors in guinea pig bronchus
J Pharmacol Exp Ther 1994 270: 1295-1300. [Abstract] [PDF]  

A Lothe, P Li, C Tong, Y Yoon, H Bouaziz, DJ Detweiler, and JC Eisenach

Spinal cholinergic alpha-2 adrenergic interactions in analgesia and hemodynamic control: role of muscarinic receptor subtypes and nitric oxide
J Pharmacol Exp Ther 1994 270: 1301-1306. [Abstract] [PDF]  

CY Chen, VF Pang, and CS Chen

Assessment of ibuprofen-associated nephrotoxicity in renal dysfunction
J Pharmacol Exp Ther 1994 270: 1307-1312. [Abstract] [PDF]  

Y Kondo, SM Kuo, and JS Lazo

Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum
J Pharmacol Exp Ther 1994 270: 1313-1318. [Abstract] [PDF]  

K Okazaki, T Ishikawa, M Inui, M Tada, K Goshima, T Okamoto, and H Hidaka

KN-62, a specific Ca++/calmodulin-dependent protein kinase inhibitor, reversibly depresses the rate of beating of cultured fetal mouse cardiac myocytes
J Pharmacol Exp Ther 1994 270: 1319-1324. [Abstract] [PDF]  

TL Knight, KM Scatchard, FN Van Pelt, and JG Kenna

Sera from patients with halothane hepatitis contain antibodies to halothane-induced liver antigens which are not detectable by immunoblotting [published erratum appears in J Pharmacol Exp Ther 1995 Feb;272(2):962]
J Pharmacol Exp Ther 1994 270: 1325-1333. [Abstract] [PDF]  

W Zhu, C Newton, Y Daaka, H Friedman, and TW Klein

delta 9-Tetrahydrocannabinol enhances the secretion of interleukin 1 from endotoxin-stimulated macrophages
J Pharmacol Exp Ther 1994 270: 1334-1339. [Abstract] [PDF]  

JL Masferrer, ST Reddy, BS Zweifel, K Seibert, P Needleman, RS Gilbert, and HR Herschman

In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages
J Pharmacol Exp Ther 1994 270: 1340-1344. [Abstract] [PDF]  

CA Fornal, WJ Litto, CW Metzler, F Marrosu, K Tada, and BL Jacobs

Single-unit responses of serotonergic dorsal raphe neurons to 5-HT1A agonist and antagonist drug administration in behaving cats
J Pharmacol Exp Ther 1994 270: 1345-1358. [Abstract] [PDF]  

CA Fornal, F Marrosu, CW Metzler, K Tada, and BL Jacobs

Effects of the putative 5-hydroxytryptamine1A antagonists BMY 7378, NAN 190 and (-)-propranolol on serotonergic dorsal raphe unit activity in behaving cats
J Pharmacol Exp Ther 1994 270: 1359-1366. [Abstract] [PDF]  

JC Kraner, ET Morgan, and JR Halpert

Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol
J Pharmacol Exp Ther 1994 270: 1367-1372. [Abstract] [PDF]  

AB Noach, M Sakai, MC Blom-Roosemalen, HR de Jonge, AG de Boer, and DD Breimer

Effect of anisotonic conditions on the transport of hydrophilic model compounds across monolayers of human colonic cell lines
J Pharmacol Exp Ther 1994 270: 1373-1380. [Abstract] [PDF]  

K Raynor, H Kong, J Hines, G Kong, J Benovic, K Yasuda, GI Bell, and T Reisine

Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor
J Pharmacol Exp Ther 1994 270: 1381-1386. [Abstract] [PDF]  

EM Unterwald, A Ho, JM Rubenfeld, and MJ Kreek

Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration
J Pharmacol Exp Ther 1994 270: 1387-1396. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1994 270: 1397. [Abstract] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.