ARTICLES:

BF Pan, A Dutt, and JA Nelson

Enhanced transepithelial flux of cimetidine by Madin-Darby canine kidney cells overexpressing human P-glycoprotein
J Pharmacol Exp Ther 1994 270: 1-7. [Abstract] [PDF]  

J Bralet, C Marie, C Mossiat, JM Lecomte, C Gros, and JC Schwartz

Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril
J Pharmacol Exp Ther 1994 270: 8-14. [Abstract] [PDF]  

PJ Bushnell, KL Kelly, and TR Ward

Repeated inhibition of cholinesterase by chlorpyrifos in rats: behavioral, neurochemical and pharmacological indices of tolerance
J Pharmacol Exp Ther 1994 270: 15-25. [Abstract] [PDF]  

HL McLeod, L Fang, X Luo, EP Scott, and WE Evans

Ethnic differences in erythrocyte catechol-O-methyltransferase activity in black and white Americans
J Pharmacol Exp Ther 1994 270: 26-29. [Abstract] [PDF]  

A Delaunois, P Gustin, and M Ansay

Modulation of the acetylcholine- and substance P-induced pulmonary edema by calcitonin gene-related peptide in the rabbit
J Pharmacol Exp Ther 1994 270: 30-36. [Abstract] [PDF]  

Y Miyamoto, WD Bowen, PS Portoghese, and AE Takemori

Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice
J Pharmacol Exp Ther 1994 270: 37-39. [Abstract] [PDF]  

T Tang, JG Kiang, and BM Cox

Opioids acting through delta receptors elicit a transient increase in the intracellular free calcium concentration in dorsal root ganglion- neuroblastoma hybrid ND8-47 cells
J Pharmacol Exp Ther 1994 270: 40-46. [Abstract] [PDF]  

K Derakhchan, P Page, C Lambert, and T Kus

Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia
J Pharmacol Exp Ther 1994 270: 47-54. [Abstract] [PDF]  

M Domae, K Yamada, T Inoue, M Satoh, and T Furukawa

Endothelins stimulate cyclic AMP accumulation in the isolated rat anterior pituitary gland: possible involvement of ETA receptor activation and prostaglandin E2 production
J Pharmacol Exp Ther 1994 270: 55-60. [Abstract] [PDF]  

LG Aguayo and FC Pancetti

Ethanol modulation of the gamma-aminobutyric acidA- and glycine- activated Cl- current in cultured mouse neurons
J Pharmacol Exp Ther 1994 270: 61-69. [Abstract] [PDF]  

JR Atack, AM Prior, SR Fletcher, K Quirk, R McKernan, and CI Ragan

Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers
J Pharmacol Exp Ther 1994 270: 70-76. [Abstract] [PDF]  

O Valverde, R Maldonado, MC Fournie-Zaluski, and BP Roques

Cholecystokinin B antagonists strongly potentiate antinociception mediated by endogenous enkephalins
J Pharmacol Exp Ther 1994 270: 77-88. [Abstract] [PDF]  

E Romeo, DL Cheney, I Zivkovic, E Costa, and A Guidotti

Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone
J Pharmacol Exp Ther 1994 270: 89-96. [Abstract] [PDF]  

M Johnson, PK Sonsalla, AA Letter, GR Hanson, and JW Gibb

Role of the 5-HT2 receptor in the methamphetamine-induced neurochemical alterations
J Pharmacol Exp Ther 1994 270: 97-103. [Abstract] [PDF]  

M Isosaki, N Minami, and T Nakashima

Pharmacological evidence for regulation of Na(+)-Ca++ exchange by Ca++/calmodulin-dependent protein kinase in isolated bovine adrenal medullary cells
J Pharmacol Exp Ther 1994 270: 104-110. [Abstract] [PDF]  

JT Gordon, EE Tomlinson, J Greenberg, and MB Dratman

An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3- induced hyperthyroid rats: implications for tricyclic antidepressant therapy
J Pharmacol Exp Ther 1994 270: 111-117. [Abstract] [PDF]  

RF Covert, MD Schreiber, IR Tebbett, and LJ Torgerson

Hemodynamic and cerebral blood flow effects of cocaine, cocaethylene and benzoylecgonine in conscious and anesthetized fetal lambs
J Pharmacol Exp Ther 1994 270: 118-126. [Abstract] [PDF]  

CS Aulakh, P Mazzola-Pomietto, KM Wozniak, JL Hill, and DL Murphy

Evidence that 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane-induced hypophagia and hyperthermia in rats is mediated by serotonin-2A receptors
J Pharmacol Exp Ther 1994 270: 127-132. [Abstract] [PDF]  

JM Masserano, D Venable, and RJ Wyatt

Effects of chronic cocaine administration on [3H]dopamine uptake in the nucleus accumbens, striatum and frontal cortex of rats
J Pharmacol Exp Ther 1994 270: 133-141. [Abstract] [PDF]  

PJ Winsauer, JF Verrees, KP O'Halloran, MA Bixler, and PC Mele

Effects of chlordiazepoxide, 8-OH-DPAT and ondansetron on radiation- induced decreases in food intake in rats
J Pharmacol Exp Ther 1994 270: 142-149. [Abstract] [PDF]  

IM Khan, P Taylor, and TL Yaksh

Cardiovascular and behavioral responses to nicotinic agents administered intrathecally
J Pharmacol Exp Ther 1994 270: 150-158. [Abstract] [PDF]  

IM Khan, TL Yaksh, and P Taylor

Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine
J Pharmacol Exp Ther 1994 270: 159-166. [Abstract] [PDF]  

A Berson, L Schmets, C Fisch, D Fau, C Wolf, B Fromenty, D Deschamps, and D Pessayre

Inhibition by nilutamide of the mitochondrial respiratory chain and ATP formation. Possible contribution to the adverse effects of this antiandrogen
J Pharmacol Exp Ther 1994 270: 167-176. [Abstract] [PDF]  

PL Prather, AW Tsai, and PY Law

Mu and delta opioid receptor desensitization in undifferentiated human neuroblastoma SHSY5Y cells
J Pharmacol Exp Ther 1994 270: 177-184. [Abstract] [PDF]  

SL Durham, CM Hare, MR Angelastro, JP Burkhart, JR Koehl, AL Marquart, S Mehdi, NP Peet, and MJ Janusz

Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase [published erratum appears in J Pharmacol Exp Ther 1994 Dec;271(3):1720]
J Pharmacol Exp Ther 1994 270: 185-191. [Abstract] [PDF]  

SP Gygi, JW Gibb, and GR Hanson

Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions
J Pharmacol Exp Ther 1994 270: 192-197. [Abstract] [PDF]  

PA Scott, JM Chou, H Tang, and A Frazer

Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists
J Pharmacol Exp Ther 1994 270: 198-208. [Abstract] [PDF]  

SB Caine and GF Koob

Effects of dopamine D-1 and D-2 antagonists on cocaine self- administration under different schedules of reinforcement in the rat
J Pharmacol Exp Ther 1994 270: 209-218. [Abstract] [PDF]  

PB Smith, DR Compton, SP Welch, RK Razdan, R Mechoulam, and BR Martin

The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice
J Pharmacol Exp Ther 1994 270: 219-227. [Abstract] [PDF]  

M Clozel, V Breu, GA Gray, B Kalina, BM Loffler, K Burri, JM Cassal, G Hirth, M Muller, and W Neidhart

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist
J Pharmacol Exp Ther 1994 270: 228-235. [Abstract] [PDF]  

PM Hellstrom, KS Murthy, JR Grider, and GM Makhlouf

Coexistence of three tachykinin receptors coupled to Ca++ signaling pathways in intestinal muscle cells
J Pharmacol Exp Ther 1994 270: 236-243. [Abstract] [PDF]  

YX Wang, GD Clarke, M Sbacchi, G Petrone, and DP Brooks

Contribution of alpha-2 adrenoceptors to kappa opioid agonist-induced water diuresis in the rat
J Pharmacol Exp Ther 1994 270: 244-249. [Abstract] [PDF]  

DC Underwood, CJ Kotzer, S Bochnowicz, RR Osborn, MA Luttmann, DW Hay, and TJ Torphy

Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs
J Pharmacol Exp Ther 1994 270: 250-259. [Abstract] [PDF]  

JW Ryan, FA Valido, MJ Sequeira, AY Chung, P Berryer, XL Chen, and JD Catravas

Estimation of rate constants for reactions of pulmonary microvascular angiotensin converting enzyme with an inhibitor and a substrate in vivo
J Pharmacol Exp Ther 1994 270: 260-268. [Abstract] [PDF]  

RJ Altiere, DC Travis, J Roberts, and DC Thompson

Pharmacological characterization of muscarinic receptors mediating acetylcholine-induced contraction and relaxation in rabbit intrapulmonary arteries
J Pharmacol Exp Ther 1994 270: 269-276. [Abstract] [PDF]  

G Cuadra, K Summers, and E Giacobini

Cholinesterase inhibitor effects on neurotransmitters in rat cortex in vivo
J Pharmacol Exp Ther 1994 270: 277-284. [Abstract] [PDF]  

KS Pang, F 3rd Barker, AJ Schwab, and CA Goresky

Demonstration of rapid entry and a cellular binding space for salicylamide in perfused rat liver: a multiple indicator dilution study
J Pharmacol Exp Ther 1994 270: 285-295. [Abstract] [PDF]  

RB Rothman, JL Cadet, HC Akunne, ML Silverthorn, MH Baumann, FI Carroll, KC Rice, BR de Costa, JS Partilla, and JB Wang

Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55
J Pharmacol Exp Ther 1994 270: 296-309. [Abstract] [PDF]  

SP Arneric, JP Sullivan, CA Briggs, D Donnelly-Roberts, DJ Anderson, JL Raszkiewicz, ML Hughes, ED Cadman, P Adams, and DS Garvey

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization
J Pharmacol Exp Ther 1994 270: 310-318. [Abstract] [PDF]  

MW Decker, JD Brioni, JP Sullivan, MJ Buckley, RJ Radek, JL Raszkiewicz, CH Kang, DJ Kim, WJ Giardina, and JT Wasicak

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization
J Pharmacol Exp Ther 1994 270: 319-328. [Abstract] [PDF]  

K Higaki, K Kadono, S Goto, and M Nakano

Stereoselective renal tubular secretion of an organic anion in the isolated perfused rat kidney
J Pharmacol Exp Ther 1994 270: 329-335. [Abstract] [PDF]  

WK Kim, RG Johnson, LT Izu, and RA Rabin

Chronic ethanol exposure inhibits ATP-stimulated but not KCl-stimulated dopamine release in PC 12 cells
J Pharmacol Exp Ther 1994 270: 336-341. [Abstract] [PDF]  

A Ohnishi, M Mihara, S Yasuda, Y Tomono, J Hasegawa, and T Tanaka

Aquaretic effect of the stable dynorphin-A analog E2078 in the human
J Pharmacol Exp Ther 1994 270: 342-347. [Abstract] [PDF]  

RW Nims, RM McClain, PS Manchand, PS Belica, PE Thomas, DW Mellini, WE Jr Utermahlen, and RA Lubet

Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat
J Pharmacol Exp Ther 1994 270: 348-355. [Abstract] [PDF]  

KK Burkhart, D Beard, and ML Billingsley

Enhanced elimination of biotinylated antibodies by avidin-based hemoperfusion in rats
J Pharmacol Exp Ther 1994 270: 356-361. [Abstract] [PDF]  

SY Sakurai, A Kume, DE Burdette, and RL Albin

Quantitative autoradiography of [3H]t-butylbicycloorthobenzoate binding to the gamma-aminobutyric acid receptorA complex
J Pharmacol Exp Ther 1994 270: 362-370. [Abstract] [PDF]  

RP Lee and PG Forkert

In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice
J Pharmacol Exp Ther 1994 270: 371-376. [Abstract] [PDF]  

LC Knickle, RM Philpot, and JR Bend

N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo
J Pharmacol Exp Ther 1994 270: 377-385. [Abstract] [PDF]  

O Pol, I Ferrer, and MM Puig

Diarrhea associated with intestinal inflammation increases the potency of mu and delta opioids on the inhibition of gastrointestinal transit in mice
J Pharmacol Exp Ther 1994 270: 386-391. [Abstract] [PDF]  

AS Salhab, CL DeVane, T Medrano, WC Buhi, IR Tebbett, and KT Shiverick

Fetoplacental growth and placental protein synthesis in rats after chronic maternal cocaine administration
J Pharmacol Exp Ther 1994 270: 392-398. [Abstract] [PDF]  

KM Metters, Y Gareau, A Lord, C Rochette, and N Sawyer

Characterization of specific binding sites for cysteinyl leukotrienes in sheep lung
J Pharmacol Exp Ther 1994 270: 399-406. [Abstract] [PDF]  

D Wu and AI Cederbaum

Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney
J Pharmacol Exp Ther 1994 270: 407-413. [Abstract] [PDF]  

T Shimada, H Yamazaki, M Mimura, Y Inui, and FP Guengerich

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians
J Pharmacol Exp Ther 1994 270: 414-423. [Abstract] [PDF]  

TP Abrahams, PJ Hornby, K Chen, AM Dasilva, and RA Gillis

The non-NMDA subtype of excitatory amino acid receptor plays the major role in control of cardiovascular function by the subretrofacial nucleus in cats
J Pharmacol Exp Ther 1994 270: 424-432. [Abstract] [PDF]  

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